FORMATION OF ?-LACTOSE FROM THE STABLE FORMS OF ANHYDROUS �-LACTOSE

1980 ◽  
Vol 45 (1) ◽  
pp. 68-70 ◽  
Author(s):  
F. W. PARRISH ◽  
K. D. ROSS ◽  
K. M. VALENTINE
2020 ◽  
Vol 17 (4) ◽  
pp. 86-95
Author(s):  
R. M. Kachalov ◽  
Yu. A. Sleptsova

The article considers the manifestations of the phenomenon of economic risk in the socioeconomic ecosystems of industrial enterprises, examines and differentiates the pragmatic and cultural aspects of the concept of "economic risk management". In terms of methodology, the study is based on the operational theory of risk management, and also uses tools to describe the organizational culture of risk management. Pragmatic and cultural differences in the characteristics of economic risk are identified at the level of stable forms of management activity with the involvement of the main provisions of the operational theory of risk management. The phenomenon of risk is considered in the ontological space as an artificial category of activity of industrial enterprises and other economic agents that form a socio-economic ecosystem. This phenomenon is studied as a specific form of social communication associated with the desire to assess the uncertain future in the present time, mainly from the point of view of analysis and management of the level of economic risk in the enterprise.


2015 ◽  
Vol 2 (2) ◽  
pp. 39-44
Author(s):  
V. Lopushniak

Aim. To establish the effect of different fertilization systems in short fi eld crop rotation on the change in the state of humus in the dark gray podzolic soils in Western Forest-Steppe of Ukraine. Methods. Field studies were carried out in a stationary experiment of the Department of Soil Science and Agricultural Chemistry of the L’viv National Agrarian University; determination of humus content – according to DSTU 4289:2004, and that of its labile forms – in accordance with DSTU 4732:2007, fraction-group composition – by Ponomare- va-Plotnikova’s method, according to the measurement procedure 31-497058-008-2002. Results. The use of organo-mineral fertilizer system in short fi eld crop rotation with the saturation of organic fertilizers of 15 t/ha of crop rotation contributes to the humus content increase by 0.7 % after the third rotation in 0–40 cm layer of dark gray podzolic soil, the increase in the share of stable forms of humic compounds up to 57–59 % and the increase in the ratio of R HA :R FA to 1.3–1.4. The study demonstrated very high dependence of amount of gross energy reserves in the humus on the R HA :R FA ratio. Conclusions. The combined application of organic fertili- zers in the form of manure, non-market of the crop (straw) and siderate, along with mineral fertilizers is re- commended in short fi eld crop rotations of Western Forest-Steppe of Ukraine toensure expanded reproduction of fertility of dark gray podzolic soil, improvement of its humus status, increase in gross energy reserves and the share of the stable forms and humic acids in the humus.


1986 ◽  
Vol 66 (1) ◽  
pp. 105-119 ◽  
Author(s):  
B. I. WAGAR ◽  
J. W. B. STEWART ◽  
J. O. MOIR

A sequential phosphorus (P) fractionation procedure was used to measure the changes in the labile and stable forms of inorganic and organic P following single broadcast P applications to Canadian Chernozemic soils under cereal cropping. Approximately half of the fertilizer residues remained in plant-available forms (resin, NaHCO3). In a Black Waskada clay loam 8 yr after the application of 200 and 400 kg P ha−1, residual fertilizer P consisted of resin-P, 30–40%; HCl-P, 25–30%; residue-P, 10–15%; NaOH-P, 10–15%, NaHCO3-P, 10%; and aggregate protected P, 3%. The residues in a Dark Brown Sutherland clay 5 yr after the application of 160 kg P ha−1 were: resin-P, 35%; NaOH-P, 30–40%; NaHCO3-P, 15%; HCl-P, 0–5%; H2SO4-P, 5%; and aggregate protected P, 5%. The soils differed in the quantity of fertilizer recovered in inorganic HCl-extractable forms. In the Sutherland soil the change from wheat-fallow to continuous wheat cropping produced a build-up of organic P which occurred with and without the addition of P fertilizer. Key words: Residual P, P transformations, Labile Pi; labile Po, stable Pi stable Po


MicroRNA ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Younes El Founini ◽  
Imane Chaoui ◽  
Hind Dehbi ◽  
Mohammed El Mzibri ◽  
Roger Abounader ◽  
...  

: Noncoding RNAs have emerged as key regulators of the genome upon gene expression profiling and genome-wide sequencing. Among these noncoding RNAs, microRNAs are short noncoding RNAs that regulate a plethora of functions, biological processes and human diseases by targeting the messenger RNA stability through 3’UTR binding, leading to either mRNA cleavage or translation repression, depending on microRNA-mRNA complementarity degree. Additionally, strong evidence has suggested that dysregulation of miRNAs contribute to the etiology and progression of human cancers, such as lung cancer, the most common and deadliest cancer worldwide. Indeed, by acting as oncogenes or tumor suppressors, microRNAs control all aspects of lung cancer malignancy, including cell proliferation, survival, migration, invasion, angiogenesis, cancer stem cells, immune-surveillance escape, and therapy resistance; and their expressions are often associated with clinical parameters. Moreover, several deregulated microRNAs in lung cancer are carried by exosomes, microvesicles and secreted in body fluids, mainly the circulation where they conserve their stable forms. Subsequently, seminal efforts have been focused on extracellular microRNAs levels as noninvasive diagnostic and prognostic biomarkers in lung cancer. In this review, focusing on recent literature, we summarize the deregulation, mechanisms of action, functions and highlight clinical applications of miRNAs for better management and design of future lung cancer targeted therapies.


2018 ◽  
Vol 8 (1) ◽  
pp. 72-80 ◽  
Author(s):  
В. Славский ◽  
V. Slavskiy ◽  
Михаил Чернышов ◽  
Mikhail Chernyshov

Given the high value of Juglans nuts, the increase in their production should not only be due to the identification and breeding of the best forms, but also by shifting the established border of cultivation to the North. In this regard, the main purpose of the work is to study and analyze the adaptive characteristics of plants in winter. The paper considers garden, park and field protection plantations, plantations, landscape groups and stand-alone trees of Juglans family nuts on adaptive signs of frost resistance and frost stability, as well as the most stable forms, which should form the basis of the breeding fund. Comparison of resistance of the genus Juglans to the various factors of ethnology gives the following results: decreasing resistance to low negative temperatures, plants can be placed as J. cenerea, J. manshurica, J. nigra, J. cordiformis, J. regia.


2021 ◽  
Author(s):  
Chihiro Kikuchi ◽  
Hina Kurane ◽  
Takuma Watanabe ◽  
Makoto Demura ◽  
Takashi Kikukawa ◽  
...  

Abstract Ion channel proteins are physiologically important molecules in living organisms. Their molecular functions have been investigated using electrophysiological methods, which enable quantitative, precise and advanced measurements and thus require complex instruments and experienced operators. For simpler and easier measurements, we measured the anion transport activity of light-gated anion channelrhodopsins (ACRs) using a pH electrode method, which has already been established for ion pump rhodopsins. Using that method, we successfully measured the anion transport activity and its dependence on the wavelength of light, i.e. its action spectra, and on the anion species, i.e. its selectivity or preference, of several ACRs expressed in yeast cells. In addition, we identified the strong anion transport activity and the preference for NO3- of an ACR from a marine cryptophyte algae Proteomonas sulcata, named PsuACR_353. Such a preference was discovered for the first time in microbial pump- or channel-type rhodopsins. Nitrate is one of the most stable forms of nitrogen and is used as a nitrogen source by most organisms including plants. Therefore, PsuACR_353 may play a role in NO3- transport and might take part in NO3--related cellular functions in nature. Measurements of a mutant protein revealed that a Thr residue in the 3rd transmembrane helix, which corresponds to Cys102 in GtACR1, contributed to the preference for NO3-. These findings will be helpful to understand the mechanisms of anion transport, selectivity and preference of PsuACR_353.


2017 ◽  
Vol 95 (5) ◽  
pp. 398-403
Author(s):  
K. Yu. Bondar ◽  
O. L. Belaya ◽  
O. M. Lazutina ◽  
I. S. Mikhailova ◽  
T. V. Smorkalova ◽  
...  

The gender-specific features of cardiovascular diseases (CVD) are actively being discussed which puts on the agenda the development of a differentiated approach to the treatment of cardiac diseases in men and women. Аim. To assess the gender-specific features of the antioxidant status and antioxidative activity of atorvastatin in patients with stable forms of coronary heart disease (CHD) and dyslipidemia (DLP). Material and methods. The study included 102 patients with stable forms of CHD divided into 2 groups according to sex and 40 healthy individuals. The generally accepted methods were used to determine plasma lipids, products of their peroxidation (diene conjugates, DC) and the products reacting with 2-thiobarbituric acid (TBA-RP), the antioxidant enzymes glutathione peroxidase (GP) and superoxide dismutase (SOD) in erythrocytes; the activity of the ceruloplasmin/transferrin antioxidant system (AOA AOS CP/TF) in blood plasma was measured by electron paramagnetic resonance and the final metabolites of nitric oxide with the use of the Griss reagent. The endothelial function was studied by ultrasound with the assessment of endothelium-dependent vasodilatation as described by D. Celermajer et al. (1992). All parameters were evaluated before and 6 months after the onset of the treatment. Results. The men with CHD, unlike women, underwent a reduction of AOA AOS CP/TF by 10%, SOD by 12% and GP by 19% (p<0.05) as well as excessive accumulation of DC up to 9% and TBA-RP to 11% (p<0.05). The homocysteine level in men, was 1.5 times higher (p=0.01), and that of final nitric oxide metabolites 12% lower (p=0.03) than in women. Atorvastatin administered for 6 months as a component of combined cardiac therapy more significantly increased the activity of AOS CP/TF and endothelium-dependent vasodilatation in men than in women. Conclusion. CHD is associated with significant sex differences in processes of lipid peroxidation - antioxidant protection, metabolism of nitric oxide, found, dilatation and anti-oxidation effect of atorvastatin.


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