High- and moderate-intensity aerobic exercise and excess post-exercise oxygen consumption in men with metabolic syndrome

2013 ◽  
Vol 24 (3) ◽  
pp. e174-e179 ◽  
Author(s):  
I. Larsen ◽  
B. Welde ◽  
C. Martins ◽  
A. E. Tjønna
2021 ◽  
Author(s):  
Ali Osali ◽  
Alireza Rostami

Abstract Backgrounds and ObjectivesThe use of anti-inflammatory supplements is important in improving the executive function of obese people. The aim of this research was to investigate the effect of 6 weeks of aerobic exercise with moderate intensity and consumption of nanocurcumin on IL1β, nitric oxide, and depression in women aged 60-65 with metabolic syndrome. Materials and Methods44 women with metabolic syndrome (MetS) were randomly selected and divided into four groups of 10, including MetS exercise+ Curcumin (MECU), MetS exercise (ME), MetS NanoCurcumin (MCU), MetS control (MC Training groups performed an exercise protocol of aerobic exercise for 6 weeks (three sessions per week). Blood samples were obtained before and after the training period for antioxidant indicators and lipid degradation measurement. Also, the Beck anxiety questionnaire was used for evaluating levels of anxiety. T-test and one-way analysis of variance were used for the evaluation of within-group and between-group differences, respectively.ResultsThere was a significant difference in IL1β, nitric oxide (NO), and depression before and after exercise in all three experimental groups (p≤0.05). Also, the results showed a significant difference in the level of NO and depression in the research groups. The highest decrease in these variables was observed in the aerobic training group and training with nanocurcumin consumption group (p≤0.05).ConclusionThese findings indicated that six-week nanocurcumin supplementation with aerobic training is a suitable method for reducing IL1β and NO and depression, preventing metabolic, cardiovascular, and inflammatory diseases in women with metabolic syndrome.Name of the registry: IR.SEMUMS.REC.1396.107Trial registration number: IRCT2017082335857N1


2020 ◽  
Vol 29 (2) ◽  
pp. 162-169
Author(s):  
Yejin Kang ◽  
Ruda Lee ◽  
Moon-Hyon Hwang ◽  
Myong-Joo Lim

PURPOSE: This study aimed to compare the acute effects of different types (treadmill vs. cycle) of moderate-intensity aerobic exercise on cerebral blood flow and cognitive function in young adults.METHODS: By a randomized crossover study design, ten participants were initially assigned to either treadmill exercise (TE; n=5) or cycle ergometer exercise (CE; n=5) and then they performed the other with seven-day wash-out period. Both exercises were implemented at the target heart rate corresponding to 70% of heart rate reserve for 30 minutes. Cognitive function was assessed by the Stroop Color-Word test at pre- and post-exercise. Cerebral blood flow was continuously monitored using near-infrared spectroscopy technique during rest, cognitive function test (CFT), and exercise.RESULTS: There was a significant group by time interaction in tissue saturation index (TSI) (<i>p</i>=.046). Post-hoc analysis presented that TSI at post-exercise CFT was higher than during exercise in TE (<i>p</i>=.02). In both exercises, TSI at pre-exercise CFT significantly increased compared to the resting value (<i>p</i>=.001). Cerebral oxyhemoglobin level was significantly increased during exercise and at post-exercise CFT compared to the resting value in both exercises (<i>p</i><.001). The reaction time for certain cognitive tasks such as color, word with matched color, word with color interference, and color with word interference was improved after both exercises (<i>p</i><.05).CONCLUSIONS: One-bout of moderate-intensity aerobic exercise acutely improves cerebral blood flow and cognitive function even in healthy young adults. Exercise types with the same intensity do not seem to make meaningful difference in the positive effects of aerobic exercise.


Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1540 ◽  
Author(s):  
Milena Barbon de Carvalho ◽  
Camila Fernanda Cunha Brandao ◽  
Priscila Giacomo Fassini ◽  
Thiago Mantello Bianco ◽  
Gabriela Batitucci ◽  
...  

Based on the fact that taurine can increase lipid metabolism, the objective of the present study was to evaluate the effects of different doses of acute taurine supplementation on lipid oxidation levels in healthy young men after a single bout of fasting aerobic exercise. A double-blind, acute, and crossover study design was conducted. Seventeen men (age 24.8 ± 4.07y; BMI: 23.9 ± 2.57 kg/m²) participated in the present study. Different doses of taurine (TAU) (3 g or 6 g) or placebo were supplemented 90 min before a single bout of fasting aerobic exercise (on a treadmill at 60% of VO2 max). The subjects performed three trials, and each one was separated by seven days. Blood samples were collected at baseline and after the exercise protocol of each test to analyze plasma levels of glycerol and taurine. Lipid and carbohydrate oxidation were determined immediately after exercise for 15 min by indirect calorimetry. We observed that TAU supplementation (6 g) increased lipid oxidation (38%) and reduced the respiratory coefficient (4%) when compared to the placebo (p < 0.05). However, no differences in lipid oxidation were observed between the different doses of taurine (3 g and 6 g). For glycerol concentrations, there were no differences between trials. Six grams of TAU supplementation 90 min before a single bout of aerobic exercise in a fasted state was sufficient to increase the lipid oxidation post-exercise in healthy young men.


Author(s):  
Jordan C. Patik ◽  
Joseph M. Stock ◽  
Ninette Shenouda ◽  
Nicholas V. Chouramanis ◽  
Justin D. Mehrer ◽  
...  

Following aerobic exercise, sustained vasodilation and concomitant reductions in total peripheral resistance (TPR) result in a reduction in blood pressure that is maintained for two or more hours. However, the time course for postexercise changes in reflected wave amplitude and other indices of pulsatile load on the left ventricle have not been thoroughly described. Therefore, we tested the hypothesis that reflected wave amplitude is reduced beyond an hour after cycling at 60% V̇O2peak for 60 min. Aortic pressure waveforms were derived in 14 healthy adults (7 men, 7 women; 26 ± 3 yr) from radial pulse waves acquired via high-fidelity applanation tonometry at baseline and every 20 min for 120 min postexercise. Concurrently, left ventricle outflow velocities were acquired via Doppler echocardiography and pressure-flow analyses were performed. Aortic characteristic impedance (Zc), forward (Pf) and backward (Pb) pulse wave amplitude, reflected wave travel time (RWTT), and wasted pressure effort were derived. Reductions in aortic blood pressure, Zc, Pf, and Pb were all sustained postexercise while increases in RWTT emerged from 60-100 min post exercise (all P<0.05). WPE was reduced by ~40% from 40-100 min post exercise (all P<0.02). Stepwise multiple regression analysis revealed that the peak ∆WPE was associated with ∆RWTT (β=-0.57, P=0.003) and ∆Pb (β=0.52, P=0.006), but not ∆cardiac output, ∆TPR, ∆Zc, or ∆Pf. These results suggest that changes in pulsatile hemodynamics are sustained for ≥100 min following moderate intensity aerobic exercise. Moreover, decreased and delayed reflected pressure waves are associated with decreased left ventricular wasted effort after exercise.


2021 ◽  
pp. 1-10
Author(s):  
S. Sugiharto ◽  
D. Merawati ◽  
H. Susanto ◽  
A. Pranoto ◽  
A. Taufiq

A passive lifestyle and lack of exercise are triggering factors in increasing metabolic syndrome, whereas metabolic syndrome is associated with increased morbidity and mortality. This study aimed to analyse an exercise-based non-pharmacological approach combined with instrumental music to the plasma levels of irisin. The study employed a randomised pretest-posttest-only group design recruiting 30 male participants. The individuals aged between 19-21 years, body mass index (BMI) 18.5-24.9 kg/m2, normal blood pressure, normal resting heart rate (RHR), VO2max 40-50 ml/kg bodyweight/min, normal haemoglobin (Hb). The subjects were randomly divided into three groups, MIE (n=10, moderate-intensity exercise), MIEM (n=10, moderate-intensity exercise + instrumental music), and HIE (n=10, high-intensity exercise). Blood sampling was collected from pre- and 5 min post-exercise treatment. ELISA method was used to measure the circulating irisin levels. The non-parametric Kruskal-Wallis test, Mann Whitney test and Spearman correlation were chosen to analyse the data. The results showed that there is no significant difference in pre-exercise irisin levels (ng/ml) in MIE (1.58±0.89), MIEM (1.77±3.12), and HIE (1.65±0.88) with a P-value of 0.098. Importantly, the alteration of irisin levels post-exercise program revealed that the level of this peptide (ng/ml) is higher in HIE (7.28±5.11) compared to MIE (1.95±1.85) and MIEM (4.16±3.40) with a P-value of 0.019. The plasma levels of irisin significantly correlate to energy expenditure (r=0.353, P≤0.01), plasma peroxisome proliferator-activated receptor gamma coactivator-1α (r=0.597, P≤0.001), and high-density lipoprotein (r=0.513, P≤0.01). In summary, increased irisin secretion may directly contribute to the gradual alteration of energy expenditure and correlate to physical exercise intensity-related musical treatment.


Author(s):  
Laura Zlibinaite ◽  
Albertas Skurvydas ◽  
Sandra Kilikeviciene ◽  
Rima Solianik

Background: The effect of globally recommended levels of physical activity on cognition and motor behavior is not completely understood. Therefore, the main aim of this study was to assess the effect of 300 minutes per week of moderate-intensity aerobic exercise on cognitive and motor performance among overweight and obese working-age women. Methods: Overweight and obese participants aged 38–56 years were randomized to either a control or an experimental group performing aerobic exercise at 50% to 60% of the peak oxygen consumption for a 2-month period. Changes in aerobic fitness, cardiac autonomic function, brain-derived neurotropic factor levels, and cognitive and motor performance were assessed. Results: Although aerobic exercise reduced body weight (P < .05) and improved peak oxygen consumption (P < .05), the brain-derived neurotropic factor levels and cognitive and motor performance remained unchanged. Heart rate and blood pressure decreased (P < .05), whereas heart rate variability indices were not affected. No significant correlations between changes in heart rate variability indices and cognition were observed. Conclusions: Two months of moderate-intensity aerobic exercise decreased sympathetic activity and improved cardiovascular fitness but had no impact on cognition or motor control among these middle-aged, overweight, and obese women.


Metabolites ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 116 ◽  
Author(s):  
Aikaterina Siopi ◽  
Olga Deda ◽  
Vasiliki Manou ◽  
Ioannis Kosmidis ◽  
Despina Komninou ◽  
...  

Exercise plays a beneficial role in the treatment of metabolic syndrome (MetS). Metabolomics can provide new insights and facilitate the optimization of exercise prescription. This study aimed to investigate whether the response of the human serum metabolic fingerprint to exercise depends on exercise mode or the presence of MetS. Twenty-three sedentary men (nine with MetS and fourteen healthy) completed four trials: Resting, high-intensity interval exercise (HIIE), continuous moderate-intensity exercise (CME), and resistance exercise (RE). Blood samples were collected pre-exercise, immediately after exercise, and 1 h post-exercise for targeted metabolomic analysis in serum by liquid chromatography–mass spectrometry. Time exerted the strongest differentiating effect, followed by exercise mode. The largest changes from baseline were found in the immediate post-exercise samples. RE caused the strongest responses overall, followed by HIIE, while CME had minimal effect. Unlike previous results in urine, no valid model could separate the two groups in serum. Exercise exerted a beneficial effect on prominent serum biomarkers of metabolic risks, such as branched-chain amino acids, alanine, acetylcarnitine, choline, and betaine. These findings contribute to the ongoing research efforts to map the molecular responses to exercise and to optimize exercise guidelines for individuals at cardiometabolic risk.


2020 ◽  
Vol 47 (1) ◽  
Author(s):  
Reham M. Shaat ◽  
Tamer O. Elsaid ◽  
Aymen EL Baz ◽  
Rehan Monir ◽  
Shereen Aly Machaly

Abstract Background Obesity and osteoarthritis are often concomitant. Both are accompanied by oxidative stress and stimulated inflammatory response. Exercise is considered a substantial treatment in rehabilitation of both conditions. Yet most of literature reported the benefits of regular exercising, while there is paucity about the effects of single low to moderate exercise session. This study aimed to investigate the possible potential effects of a single bout of moderate exercise in obese middle-aged individuals with knee osteoarthritis (KOA). Results Score of pain and Western Ontario and Mc-Master University (WOMAC) had been improved 24 h after exercise. Glutathione reductase (GR) activity increased post-exercise but decreased the next 24 h though remained higher than baseline. Blood glucose level was reduced post-exercise whereas blood lipids still uninfluenced by exercise. Markers of inflammation remained unchanged after exercise session. Conclusion A single bout moderate-intensity aerobic exercise is effective in improving pain and antioxidant activity among middle-aged obese patients with primary knee OA. Single bout of mild to moderate exercise may help in treatment of obese patients with KOA. Trial registration Clinical Trials.gov Identifier: NCT03927339


2016 ◽  
Vol 33 (01) ◽  
pp. 032-036
Author(s):  
L. Sousa ◽  
S. Saucedo ◽  
A. Veloso ◽  
J. Machi ◽  
R. Wichi ◽  
...  

Abstract Introduction: Metabolic syndrome (MS) corresponds to a sum of alteration in which, glucose intolerance is characterized as one of the most important. Among these are included: insulin resistance, type 2 diabetes mellitus, hypertension, obesity, dyslipidemia, endothelial dysfunction and others Nonalcoholic steatohepatitis (NASH) is also currently cited as a risk factor for MS Studies have demonstrated a strong correlation between physical inactivity and MS. The aim of this paper was to evaluate the effects of aerobic exercise training of different intensities on the liver of metabolic syndrome rats. Methods: 20 male Wistar rats were used and divided into four groups (n=5): control (C) sedentary MS (MS), walking MS (WMS) and running MS (RMS). Fructose-drinking rats received D-fructose (100 g/l). MS Training rats were assigned to a treadmill training protocol at low and moderate intensity during 1 h/day, 5 days/week for 8 weeks. At the end of the experiment, the livers were collected and submitted to a histological technique (HE). The images were captured and morphometric and stereological analysis of the hepatic tissue were performed. Results: It was verified that MS promoted a hypertrophy of the hepatocytes, a significant increase in the density volume of the hepatocytes, of the Kupffer cells, and hepatic sinusoids, and that, in both intensities (Running and Walking) the exercise training has mitigated the alterations. Conclusions: The data suggest, as nonpharmacological treatment, the walking (low intensity) is the most eficient, able to reverse the alterations caused by metabolic syndrome, the results being approximate to those of control group.


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