Thermal Environmental Effect on Breast Tumor Growth

2009 ◽  
Author(s):  
Na Ma ◽  
Ping Liu ◽  
Chao Chen ◽  
Aili Zhang ◽  
Lisa X. Xu
Keyword(s):  
Oxidative Phosphorylation ◽  
Atp Hydrolysis ◽  
Malignant Tumors ◽  
Performance Status ◽  
Symptomatic Improvement ◽  
The Body ◽  
Hyperthermia Treatment ◽  
Short Period ◽  
The Relationship

Tissue hypoxia is a common and important feature of rapidly growing malignant tumors and their metastases. Tumor cells mainly depend on energy production thru anaerobic glycolysis rather than aerobic oxidative phosphorylation in mitochondria [1]. Intervening the tumor metabolic process via thermal energy infusion is worthy attempting. And hyperthermia, mildly elevated local temperature above the body temperature, is one of such kind. Previously, after being heated for a short period of time, tumor glucose and lactate level increased and ATP level decreased, which suggested energy metabolism was modified following hyperthermia through increased ATP hydrolysis, intensified glycolysis and impaired oxidative phosphorylation [2]. Many researchers designed experiments to determine thermal dose in hyperthermia [3], but few focused on the relationship between tumor and energy, especially for a long-term local hyperthermia treatment. One clinical trial indicated the effective long-term hyperthermo-therapy for maintaining performance status, symptomatic improvement, and prolongation of survival time in patients with peritoneal dissemination [4].

Fear of the Thirty Years War

Facing Fear ◽  
2012 ◽  
Author(s):  
David Lederer
Keyword(s):  
Political Culture ◽  
Body Politic ◽  
The Body ◽  
Fear Response ◽  
The Relationship

This chapter explores the relationship between fears and crises by focusing on the Thirty Years War. It considers how the war evoked a universal fear response and highlights expressions of preexisting apocalyptic fears in the material context of a long-term crisis. It also examines universal and traditional elements in contemporary portrayals of fear aroused by the specific events of the war. During the Thirty Years War, the body politic often appeared twisted, contorted, or monstrous in form, suggesting a fearful condition affecting society as a whole. In other words, the body functioned as a repository of fear during the conflict. The chapter argues that the linchpin of the relationship between crises and fear during the Thirty Years War was their literal embodiment by contemporary political culture and a peculiar understanding of history.

scholarly journals The Digital Heritage of Covid-19 's Governance: How to Upgrade and Use the "Health Code" in the Post-Epidemic Era

2021 ◽  
Vol 2 (2) ◽  
pp. 235-241
Author(s):  
Wu Siqi ◽  
Wu Yi
Keyword(s):  
Digital Media ◽  
The Body ◽  
Ethical Problems ◽  
Digital Heritage ◽  
Full State ◽  
The Media ◽  
Digital Projection ◽  
And Control ◽  
The Relationship

The outbreak of Covid-19 accelerated the practice of digital survival, and the "health code" launched based on the needs of epidemic prevention and control has become the representative of digital survival media, which is jointly built by science and technology enterprises and government departments. it has realized the full-state use in China, and accumulated long-term digital survival experience for the country, enterprises and individuals. At the same time, there are some media ethical problems in the use of Health Code, such as distinguishing users, leaking information, imprisoning the body and leading to the lack of subjects. In order to resolve the risk, we should re-examine the relationship between people and the media from the perspective of the subject, treat "health code" as a digital projection of personal health, and regain the service principle of digital technology. Humanize the "health code" and other digital media.

scholarly journals PATHOMORPHOLOGICAL CHANGES IN THE ORGANS OF A CAT WITH ADENOCARCINOMA

2021 ◽  
Vol 247 (3) ◽  
pp. 70-74
Author(s):  
I.N. Zalyalov ◽  
◽  
E.N. Bulatova ◽  
I.S. Konstantinova ◽  
◽  
...  
Keyword(s):  
Statistical Data ◽  
Malignant Tumors ◽  
The Body ◽  
Cytological Diagnosis ◽  
Functional Disorders ◽  
Large Cities ◽  
Oncological Diseases ◽  
Domestic Carnivores ◽  
Oncological Pathology

Oncological diseases of unproductive animals are becoming increasingly common in veterinary practice, especially in large cities. The basis of tumor growth is the unlimited uncontrolled reproduction of cells by the body, which leads to a complex of structural and functional disorders. Despite the significant achievements of modern veterinary medicine in the field of diagnosis of benign and malignant tumors in animals, the issues of histological and cytological diagnosis of the forms of manifestation of this pathology remain problematic. Long-term statistical data show that there is a tendency to increase the incidence of oncological pathology in domestic carnivores, especially in the malignant form.

scholarly journals The Implementation of Embodied Learning: A Literature Review

Edukasi ◽  
2021 ◽  
Vol 15 (1) ◽  
pp. 8-18
Author(s):  
Yulvia Sani ◽  
Ossy Firstanti Wardany ◽  
Heni Herlina ◽  
Genesa Vernanda
Keyword(s):  
Literature Review ◽  
Foreign Language ◽  
Motor Skills ◽  
The Body ◽  
Long Term Memory ◽  
Learning Approach ◽  
Embodied Learning ◽  
Psychology Education ◽  
The Relationship

This literature review aims to determine the implementation of the embodied learning approach in children. The research method used is a narrative review of ten articles that have met the criteria. The criteria for the article are to be found in Google Scholar, published in the last 8 years (2012-2021), and the title contains "Embodied Learning". There are five things that are studied, namely the concept of embodied learning; the relationship between psychology, education, and the environment; student age; tools and materials (technology); and materials that can be provided through an embodied learning approach. This literature review shows that embodied learning is a learning approach that emphasizes the involvement of the body in the process of receiving and responding to the material. Embodied learning can be implemented to improve children's language skills, motor skills, memory skills, and learning foreign language material. The ages of students who accept this embodied learning approach are range from 4 years to 12 years, or kindergarten and elementary school ages. From the ten articles studied, it was found that the involvement of the body in the learning process can build information in students' long-term memory.

scholarly journals Effects of preweaning nutritional deprivation on basal metabolism and thermoregulatory thermogenesis in the rat

1986 ◽  
Vol 56 (3) ◽  
pp. 615-623 ◽  
Author(s):  
D. V. Muralidhara ◽  
P. S. Shetty
Keyword(s):  
Body Size ◽  
The Body ◽  
Metabolic Efficiency ◽  
Nutritional Rehabilitation ◽  
Adequate Diet ◽  
Nutritional Deprivation ◽  
Short Period ◽  
Body Weights ◽  
Before And After

1. Nutritional deprivation was induced preweaning in Wistar rats by increasing the litter size to sixteen, while paired litters with only five pups served as controls. The nutritionally deprived pups were rehabilitated after weaning by ad lib. access to an adequate diet.2. The body-weights and body lengths were significantly lower in the nutritionally deprived group and significant differences persisted even after 9 weeks of rehabilitation.3. The body temperature of the nutritionally deprived animals was significantly lower than that of their paired controls, both before and following nutritional rehabilitation, except for a short period after weaning when the nutritionally deprived animals were initially given the diet ad lib.4. The resting oxygen consumption of the nutritionally deprived animals was comparable to that of the controls when corrected for metabolic body size, both before and after weaning. Noradrenaline-stimulated increase in 02 consumption (non-shivering thermogenesis; NST) was reduced by 50% at weaning in the nutritionally deprived animals and returned to levels comparable to those of controls within a short period of rehabilitation.5. The decrease in NST capacity seen in the nutritionally deprived animals was associated with an inability to thermoregulate when exposed to cold (5°), resulting in death. Cold-induced thermogenesis (CIT) also reappeared soon after nutritional rehabilitation.6. Reduction in metabolic rate, NST and CIT seen in the animals nutritionally deprived preweaning was short-lived and disappeared soon after nutritional rehabilitation. Rapid reversal of these physiological changes indicates that they do not confer any long-term benefit or change in metabolic efficiency and are unlike the changes in body size and growth which do not completely recover following nutritional rehabilitation.

scholarly journals A General Origin for Multiplanetary Systems With Significantly Misaligned USP Planets

2021 ◽  
Vol 162 (6) ◽  
pp. 242
Author(s):  
L. Brefka ◽  
J. C. Becker
Keyword(s):  
Perturbation Theory ◽  
The Past ◽  
Short Period ◽  
Mutual Inclination ◽  
Dynamical Parameters ◽  
Orbital Periods ◽  
Star Ages ◽  
The Relationship ◽  
Host Stars

Abstract Ultra-short-period (USP) planets are exoplanets that have orbital periods of less than one day and are unique because they orbit inside the nominal magnetic truncation gap of their host stars. In some cases, USP planets have also been observed to exhibit unique dynamical parameters such as significant misalignments in inclination angle with respect to nearby planets. In this paper, we explore how the geometry of a multiplanet system hosting a USP planet can be expected to evolve as a star ages. In particular, we explore the relationship between the mutual inclination of the USP planet and the quadrupole moment (J 2) of the host star. We use secular perturbation theory to predict the past evolution of the example TOI-125 system, and then confirm the validity of our results using long-term N-body simulations. Through investigating how the misalignment between the candidate USP planet and the three other short-period planets in the TOI-125 system arose, we intend to derive a better understanding of the population of systems with misaligned USP planets and how their observed parameters can be explained in the context of their dynamical histories.

scholarly journals Embodied intersubjectivity, sedimentation and non-actual motion expressions

2016 ◽  
Vol 39 (2) ◽  
pp. 185-208 ◽  
Author(s):  
Jordan Zlatev ◽  
Johan Blomberg
Keyword(s):  
Cognitive Linguistics ◽  
Mental Simulation ◽  
The Body ◽  
Linguistic Meaning ◽  
The Road ◽  
Actual Motion ◽  
Linguistic Conventions ◽  
The Relationship ◽  
Embodied Intersubjectivity

As part of a long-term project investigating the relevance of phenomenology for (cognitive) linguistics we analyse two central, interrelated concepts:embodied intersubjectivity(intercorporeality) andsedimentation. With respect to the first, we spell out a number of different intercorporeal structures, emanating at the most fundamental level from the dualLeibkörpernature of the body. Further, we demonstrate that sedimentation is more than a ‘geological metaphor’ as meaning is intrinsically layered in human experience. This is first illustrated by reviewing evidence from ontogenetic semiotic development within the framework of the Mimesis Hierarchy model (Zlatev 2013). Then, we focus on the linguistic construal of situations lacking actual motion in dynamic terms through expressions of non-actual motion such asThe road goes through the forestandHe was uplifted by her smile. We review studies of non-actual motion in Swedish, English, French, Bulgarian and Thai extending and re-formulating previous analyses. We argue that the present analysis is more adequate than cognitive linguistic explanations in terms of ‘mental simulation’ and ‘conceptual metaphor’. We conclude by pointing out how our phenomenological investigation can help resolve a number of classical dilemmas in semantics: Is language primarily grounded in the body or in society? Is the ontology of linguistic meaning mental or social? What is the relationship between pre-linguistic experiences and linguistic conventions?

The Relationship of Height and Weight Velocities of Adolescent Boys to the Total Hydroxyproline:Creatinine Ratio in Their Random Urines

1973 ◽  
Vol 44 (4) ◽  
pp. 359-365 ◽  
Author(s):  
B. A. Wharton ◽  
G. Gough ◽  
C. A. Pennock
Keyword(s):  
Growth Rate ◽  
Growth Velocity ◽  
Adolescent Boys ◽  
Short Period ◽  
Relationship Of ◽  
The Relationship ◽  
Sequential Studies

1. The total hydroxyproline:creatinine ratios in random urines collected every 3 months for 1 year from twenty-six adolescent boys (11–14 years) have been compared with the observed height and weight velocities of the boys during that year. 2. There were significant correlations of both height and weight velocities over 6 and 12 month periods with the ratios in the random urines collected during the same period. 3. The ratio in most boys fell from July to April and then rose during the final 3 months of the study. Sequential changes in the ratio correlated significantly with sequential changes in growth velocity (i.e. acceleration or deceleration) but the changes in the ratio occurring throughout the year could not be wholly explained by variation in growth rate. 4. The urinary total hydroxyproline:creatinine ratio is probably most useful as an index of growth rate in comparisons between children studied over the same period of time, or in sequential studies of the same child over a short period. In long-term sequential studies allowances must be made for factors other than growth velocity so that interpretation is more difficult.

scholarly journals Impact of Knowledge-based Program Management Resource on Social Enterprise Sustainability: A Structural Equation Modelling Approach

2021 ◽  
Vol VI (I) ◽  
pp. 130-142
Author(s):  
Arif-Ud-Din ◽  
Syed Mohsin Ali Shah ◽  
Muhammad Jahangir
Keyword(s):  
Structural Equation Modelling ◽  
Social Enterprise ◽  
Structural Equation ◽  
The Body ◽  
Substantial Impact ◽  
Knowledge Based ◽  
Equation Modelling ◽  
Starting Point ◽  
The Relationship

The focus of this research is to look at knowledge-based programme management resources as a starting point for investigating the relationship between Team programme management resources and social enterprise sustainability in underdeveloped countries. This article examines data from 300 programme management personnel of social businesses in Pakistan who responded to a self-administered and online survey. The link between team programme management resources and social business sustainability was investigated using structural equation modelling (CB-SEM). A total of 9 critical indicators of the team programme management assets have a substantial impact on the three sustainability pillars (Social, economic and environmental). This research contributes to the understanding of the relationship between programme management resources and the long-term sustainability of social enterprises. Few publications have looked into intangible programme management resources as a basis of sustainability using the RBV of the organization. This study adds to the body of knowledge on the RBV of the business and advances our consideration of programme management resources as a foundation of long-term sustainability.

scholarly journals Body Representations and Cognitive Ontology: Drawing the boundaries of the body image

2019 ◽  
Author(s):  
Stephen Gadsby
Keyword(s):  
Body Image ◽  
Cognitive Neuroscience ◽  
Body Schema ◽  
Body Representation ◽  
The Body ◽  
Reciprocal Interaction ◽  
Body Representations ◽  
Alice In Wonderland ◽  
The Relationship

The distinction between body image and body schema has been incredibly influential in cognitive neuroscience. Recently, researchers have begun to speculate about the relationship between these representations (Gadsby, 2017; 2018; Pitron & de Vignemont, 2017; Pitron et al., 2018). Within this emerging literature, Pitron and colleagues (2018) proposed that the long-term body image and long-term body schema co-construct one another, through a process of reciprocal interaction. In proposing this model, they make two assumptions: that the long-term body image incorporates the spatial characteristics of tools, and that it is distorted in the case of Alice in wonderland syndrome. Here, I challenge these assumptions, with a closer examination of what the term “long-term body image” refers to. In doing so, I draw out some important taxonomic principles for research into body representation.

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