THE LONG-TERM EFFECTS OF AEROBIC TRAINING VERSUS COMBINED TRAINING ON PHYSICAL FITNESS AND CARDIOVASCULAR DISEASES RISK FACTORS IN OVERWEIGH ELDERLY MEN WITH HIGH BLOOD PRESSURE

2013 ◽  
Vol 47 (10) ◽  
pp. e3.15-e3
Author(s):  
Nelson Sousa ◽  
Romeu Mendes ◽  
Catarina Abrantes ◽  
Jaime Sampaio ◽  
José Oliveira
2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
H Bergum ◽  
I Sandven ◽  
TO Klemsdal

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): The Norwegian health department Background The evidence of the long-term effects of multiple lifestyle intervention on cardiovascular risk is uncertain. We aimed to summarize the evidence from randomized clinical trials examining the efficacy of lifestyle intervention on major cardiovascular risk factors in subjects at high cardiovascular risk. Methods  Eligible trials investigated the impact of lifestyle intervention versus usual care with minimum 24 months follow-up, reporting more than one major cardiovascular risk factor. A literature search updated April 15, 2020 identified 12 eligible studies. The results from individual trials were combined using fixed and random effect models, using the standardized mean difference (SMD) to estimate effect sizes. Small-study effect was evaluated, and heterogeneity between studies examined by subgroup and meta-regression analyses considering patient- and study-level variables. Results  Small-study effect was not identified. Lifestyle intervention reduced systolic blood pressure modestly with an estimated SMD of -0.13, 95% confidence interval (CI): -0.21 to -0.04, with moderate heterogeneity (I² = 59%), corresponding to a mean difference of approximately 2 mmHg (MD = -1.86, 95% CI: -3.14 to -0.57, p = 0.0046). This effect disappeared in the subgroup of trials judged at low risk of bias (SMD = 0.02, 95% CI: -0.08 to 0.11). For the outcome total cholesterol SMD was -0.06, 95% CI: -0.13 to 0.00, with no heterogeneity (I² = 0%), indicating no effect of the intervention. Conclusion  Lifestyle intervention resulted in only a modest effect on systolic blood pressure and no effect on total cholesterol after 24 months. Further lifestyle trials should consider the challenge of maintaining larger long-term benefits to ensure impact on cardiovascular outcomes.


2020 ◽  
Vol 9 (6) ◽  
pp. 1810
Author(s):  
E. Venturini ◽  
G. Iannuzzo ◽  
A. D’Andrea ◽  
M. Pacileo ◽  
L. Tarantini ◽  
...  

Cancer and cardiovascular diseases are globally the leading causes of mortality and morbidity. These conditions are closely related, beyond that of sharing many risk factors. The term bidirectional relationship indicates that cardiovascular diseases increase the likelihood of getting cancer and vice versa. The biological and biochemical pathways underlying this close relationship will be analyzed. In this new overlapping scenario, physical activity and exercise are proven protective behaviors against both cardiovascular diseases and cancer. Many observational studies link an increase in physical activity to a reduction in either the development or progression of cancer, as well as to a reduction in risk in cardiovascular diseases, a non-negligible cause of death for long-term cancer survivors. Exercise is an effective tool for improving cardio-respiratory fitness, quality of life, psychological wellbeing, reducing fatigue, anxiety and depression. Finally, it can counteract the toxic effects of cancer therapy. The protection obtained from physical activity and exercise will be discussed in the various stages of the cancer continuum, from diagnosis, to adjuvant therapy, and from the metastatic phase to long-term effects. Particular attention will be paid to the shelter against chemotherapy, radiotherapy, cardiovascular risk factors or new onset cardiovascular diseases. Cardio-Oncology Rehabilitation is an exercise-based multi-component intervention, starting from the model of Cardiac Rehabilitation, with few modifications, to improve care and the prognosis of a patient’s cancer. The network of professionals dedicated to Cardiac Rehabilitation is a ready-to-use resource, for implementing Cardio-Oncology Rehabilitation.


1985 ◽  
Vol 3 (4) ◽  
pp. 403
Author(s):  
K Dorst ◽  
H Lehnert ◽  
K Kaluza ◽  
H Schmidt ◽  
H Vetter ◽  
...  

2018 ◽  
Vol 64 (1) ◽  
pp. 7-11
Author(s):  
José Pacheco-Romero

The 2017 ACC/AHA/AAPA/ABC/ACPM/ AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults published in November 2017(1) designates new categories of blood pressure in adults: Normal <120/140/>90 mm Hg. A previous report based on blood pressure readings in 19.1 million adults pooled from 1 479 studies found that the global age-standardized prevalence of raised blood pressure was 24.1% (21.4–27.1) in men and 20.1% (17.8–22.5) in women in 2015(2). The Peruvian Tornasol II study on Risk Factors for Cardiovascular Diseases reported in 2011 a prevalence of 27.3% for arterial hypertension(3), showing an increase compared to the previous value of 23.7% in 2006(4).


2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e19009-e19009 ◽  
Author(s):  
Jade Jones ◽  
Binsah George ◽  
Christine B Peterson ◽  
Jan Andreas Burger ◽  
Nitin Jain ◽  
...  

e19009 Background: Ibrutinb is approved for treatment of CLL. Hypertension (HTN) has been reported as a side effect of ibrutinib in 1-23% of patients. We previously reported HTN in CLL patients after 6 months of treatment with ibrutinib. In this study we describe the effects of long-term treatment with ibrutinib on blood pressure (BP). Methods: We performed a retrospective study, evaluating 150 CLL patients on ibrutinib-based clinical trials from 2010 to 2015. Patient demographics, co-morbidities, tobacco use, anti-HTN therapy were recorded. BP was evaluated at baseline and sequentially for up to 5 yrs. New onset HTN was defined as systolic BP (SBP) of ≥ 130 mmHg and/or diastolic BP (DBP) ≥ 80 on two separate visits with no prior HTN or anti-HTN therapy. An increase in baseline SBP by ≥10 and/or increase in DBP by ≥10 was considered significant regardless of the absolute BP. Univariate logistic regression analysis was performed to assess relationship of HTN risk factors and new HTN. Results: Patients’ median age was 65 yrs (68% male and 88% white). Median follow-up was 3 yrs. Pre-existing HTN was present in 44% of patients, 40% were on anti-HTN therapy prior to ibrutinib. New HTN developed in 65% of patients without prior diagnosis of HTN; 32 % of patients were started on anti-HTN therapy or received additional anti-HTN therapy. Of the patients who experienced an increase in BP, 33% experienced isolated systolic HTN. Median SBP was 130 at baseline, 132 at 1mo, 137 at 3mo, 135 at 6mo, 139 at 12mo, 138 at 3yrs, 144 at 5yrs (mean increase in SBP: 7.2, P < 0.001). In patients whose SBP was < 130 at baseline the median SBP was 119 at baseline, 122 at 1mo, 134 at 3mo, 130 at 6mo, 134 at 12mo, 135 at 3yrs and 141 at 5yrs (mean increase in SBP: 15.7, p < 0.001). 74% of patients experienced and increase in SBP ≥10. New HTN on ibrutinib was not associated with: tobacco use, obesity, chronic kidney disease or obstructive sleep apnea (p > 0.05). Conclusions: In this study we demonstrated a high rate of new HTN in patients on prolonged ibrutinib treatment. HTN in these patients is persistent, linear and independent of other risk factors. The increase in BP remained despite initiation of anti-HTN therapy. Additional studies are ongoing to define cardiovascular and renal complications associated with HTN in these patients.


2020 ◽  
Vol 28 (6) ◽  
pp. 962-970
Author(s):  
Thaís Reichert ◽  
Rochelle Rocha Costa ◽  
Bruna Machado Barroso ◽  
Vitória de Mello Bones da Rocha ◽  
Henrique Bianchi Oliveira ◽  
...  

The aim of the study was to compare the effects of three water-based training on blood pressure (BP) in older women. A total of 57 participants were randomized into the following groups: (a) aerobic training (AT), (b) concurrent training in which resistance training progresses to the use of resistive equipment (CTRE), and (c) concurrent training in which resistance training progresses to multiple sets (CTMS). The participants trained twice a week for 16 weeks. Systolic BP decreased from pretraining to after 8 weeks of training and, subsequently, to after 16 weeks of training (AT: −6.53 mmHg, CTRE: −10.45 mmHg, and CTMS: −10.73 mmHg). Diastolic BP decreased from pretraining to after 8 and 16 weeks of training (AT: −6.23 mmHg, CTRE: −4.61 mmHg, and CTMS: −6.19 mmHg). Furthermore, 16% of the AT participants, 23% of the CTRE participants, and 28.5% of the CTMS participants were no longer classified as hypertensive. Water-based aerobic and concurrent training are efficient nonpharmacological measures to reduce BP in older women.


2020 ◽  
Vol 6 (3) ◽  
pp. 7-11
Author(s):  
S. V. Romanov ◽  
M. N. Doronina ◽  
O. P. Abaeva ◽  
N. G. Shilova ◽  
E. K. Sokolovskaya

The purpose of the study. To study the health status of employees of the sea, river fleet and mixed river — sea navigation on the basis of the results of mandatory periodic and preliminary medical examinations.Materials and methods. The results of inspections of 2048 employees became the materials of the investigation. Results. There is a high incidence of respirator, endocrine and cardiovascular diseases, which is formed against the background of exposure to a number of risk factors, primarily smoking and high blood pressure. Conclusion. The most important component of health protection for this contingent of employees is the quality of preliminary and periodic medical examinations, the results of which will allow timely identification of chronic noncommunicable diseases and form a set of necessary rehabilitation measures.


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