scholarly journals Prevalence and factors associated with fatigue in the Lausanne middle-aged population: a population-based, cross-sectional survey

BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e027070 ◽  
Author(s):  
Coralie Galland-Decker ◽  
Pedro Marques-Vidal ◽  
Peter Vollenweider

ObjectiveTo assess the prevalence and factors associated with fatigue in the general population.DesignPopulation-based, cross-sectional survey performed between May 2014 and April 2017.SettingGeneral population of the city of Lausanne, Switzerland.Participants2848 participants (53.2% women, age range 45–86 years).Primary outcome measurePrevalence of fatigue the previous week, defined as a score of ≥4 using the Fatigue Severity Scale.ResultsThe prevalence of fatigue was 21.9% (95% CI 20.4% to 23.4%) in the total sample. On bivariate analysis, participants with fatigue were younger, had a higher body mass index, a lower handgrip strength and lower ferritin levels. Participants with fatigue were more frequently women, had a lower educational level, presented more frequently with clinical insomnia, diabetes, anaemia, depression and low thyroid stimulating hormone (TSH) values, had a higher consumption of antihistamines, antidepressants and hypnotics, and rated more frequently their health as bad or very bad. Multivariable analysis showed that obesity (OR 1.40 (95% CI 1.03 to 1.91)), insomnia categories (p value for trend <0.001), depression (OR 3.26 (95% CI 2.38 to 4.46)), anaemia (OR 1.70 (95% CI 1.00 to 2.89)) and low self-rated health status (p value for trend <0.001) were positively associated with fatigue, while older age (p value for trend 0.002) was negatively associated with fatigue. Conversely, no association was found for diabetes, TSH levels, antihistamines or hypnotics.ConclusionIn a population-based sample aged 45–86, fatigue was present in one out of five subjects. Regarding clinical factors, sleep disturbances such as insomnia and sleep apnoea should be assessed first, followed by depression. Regarding biological factors, anaemia should be ruled out, while screening for hypothyroidism is not recommended as a first step. Sleep complaints and fatigue in older subjects are not due to ageing and should prompt identification of the underlying cause.

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
V Chekanova ◽  
P Marques-Vidal ◽  
N Abolhassani

Abstract Funding Acknowledgements Type of funding sources: None. Aims Identify the clinical and genetic factors associated with poor control of high cholesterol in the Swiss population. Methods Data from three waves [baseline, N = 617; first, N = 844 and second, N = 798 follow-ups] of a population-based, prospective study conducted in Lausanne, Switzerland. Inadequate management of dyslipidemia was assessed according to the most common Swiss guideline. Genetic scores for lipid levels were computed based on the existing literature. Results Prevalence of inadequately managed dyslipidemia was 30%, 31.5% and 17.4% in the baseline, first and second follow-up. On multivariable analysis, participants at high risk of CVD had a lower likelihood of being adequately managed: odds ratio (OR) and (95% confidence interval) for high-risk relative to low-risk: 0.10 (0.06-0.18), 0.11 (0.07-0.17) and 0.15 (0.09-0.27) for the baseline, first and second follow-up (p for trend &lt; 0.001). Use of more potent statins increased the likelihood of adequate management, OR and (95% CI) for third vs. first level: 2.89 (1.76-4.74) and 5.17 (2.51-10.6) in the first and second follow-up (p for trend &lt; 0.001). No differences in total cholesterol, LDL and HDL genetic scores were found between adequately and inadequately managed participants: for the total cholesterol, -3.7 ± 9.6 vs. -2.7 ± 9.4; -3.5 ± 8.9 vs. -3.7 ± 9.5 and -3.8 ± 8.9 vs. -3.3 ± 9.4 in the baseline, first and second follow-up, p = NS. Those findings were replicated when the thresholds for adequate control were relaxed. Conclusion Management of dyslipidemia is suboptimal in Switzerland. Use of newer, more potent statins in high-risk patients could improve this status. The use of genetic scores appears to be of little interest. Multivariate Analysis First FUOR (95% CI) p-value Second FUOR (95% CI) p-value CVD risk Intermediate 0.18 (0.10 - 0.32) &lt;0.001 0.22 (0.09 - 0.55) 0.001 High 0.07 (0.04 - 0.12) &lt;0.001 0.09 (0.04 - 0.2) &lt;0.001 p-value for trend &lt;0.001 &lt;0.001 Swiss vs Non-Swiss 1.34 (0.87 - 2.05) 0.181 0.79 (0.43 - 1.43) 0.428 FH dyslipidemia (yes/no) 1.02 (0.63 - 1.63) 0.948 0.55 (0.29 - 1.03) 0.060 Statins potency First 1 (ref.) 1 (ref.) Second 2.00 (1.22 - 3.27) 0.006 2.59 (1.23 - 5.44) 0.012 Third 2.89 (1.76 - 4.74) &lt;0.001 5.17 (2.51 - 10.6) &lt;0.001 p-value for trend &lt;0.001 &lt;0.001


2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
N. E. Udonwa ◽  
E. K. Uko ◽  
B. M. Ikpeme ◽  
I. A. Ibanga ◽  
B. O. Okon

A population-based-cross-sectional survey was carried out to investigate the potential risk of exposure to premium motor spirit (PMS) fumes in Calabar, Nigeria, among Automobile Mechanics (AM), Petrol Station Attendants (PSA) and the general population. Structured questionnaire was administered on the randomly chosen subjects to elicit information on their exposure to PMS. Duration of exposure was taken as the length of work in their various occupations. Venous blood was taken for methaemoglobin (MetHb) and packed cells volume (PCV). Mean MetHb value was higher in AM (7.3%) and PSA (5.8%) than in the subjects from the general population (2.7%). PCV was lower in PSA (30.8%), than AM (33.3%) and the subjects from the general population (40.8%). MetHb level was directly proportional, and PCV inversely related, to the duration of exposure. The study suggested increased exposure to petrol fumes among AM, PSA, and MetHb as a useful biomarker in determining the level of exposure to benzene in petrol vapour.


Author(s):  
Hesteria F.A.S ◽  
I.W.G. Artawan Eka Putra ◽  
Dyah Pradnyaparamita Duarsa

Background and purpose: Working mothers and mothers who leave their babies in their home for more than 8 hours a day almost do not exclusively breastfeed their babies. The aim of this study was to determine the proportion of exclusive breastfeeding among mothers who work at home and factors associated with it.Methods: Cross-sectional survey was conducted by convenience sampling of 132 mothers with 6-12 months babies at Puskesmas Marga I Tabanan Regency from March-April 2016. The data was collected by interview about social-demographic characteristic, knowledge, perception, pregnancy and maternity counseling, early breastfeeding initiation, families support, medical assistant and exclusive breastfeeding. The data analyzed by univariate, bivariate, multivariate using STATA 12.1. Chi square applied in bivariate analysis and poison regression applied in multivariate analysis.Results: Proportion of respondents who exclusively breastfeed their babies for 6 months was 66.67%. Reasons for not exclusively breastfeed were not enough breastmilk (32.58%), no breastmilk (13.64%), families suggestion (8.33%), babies refused breastmilk (6.06%), health provider suggestion (2.27%) and to avoid the shape of the breast (1.52%). Multivariate analysis found that variables associated with the exclusive breastfeeding were parity (APR=1.50; 95%CI: 1.01-2.15), early breasfeeding initiation (APR=1.80; 95%CI: 1.13-2.90) and families support (APR=1.4; 95%CI: 1.10-1.76).Conclusion: Factors significantly associated with exclusive breastfeeding were parities less than 3, early breasfeeding initiation and families support.


2020 ◽  
Vol 5 (4) ◽  
pp. e002141
Author(s):  
Elise Farley ◽  
Modupe Juliana Oyemakinde ◽  
Jorien Schuurmans ◽  
Cono Ariti ◽  
Fatima Saleh ◽  
...  

BackgroundNoma, a rapidly progressing infection of the oral cavity, mainly affects children. The true burden is unknown. This study reports estimated noma prevalence in children in northwest Nigeria.MethodsOral screening was performed on all ≤15 year olds, with caretaker consent, in selected households during this cross-sectional survey. Noma stages were classified using WHO criteria and caretakers answered survey questions. The prevalence of noma was estimated stratified by age group (0–5 and 6–15 years). Factors associated with noma were estimated using logistic regression.ResultsA total of 177 clusters, 3499 households and 7122 children were included. In this sample, 4239 (59.8%) were 0–5 years and 3692 (52.1%) were female. Simple gingivitis was identified in 3.1% (n=181; 95% CI 2.6 to 3.8), acute necrotising gingivitis in 0.1% (n=10; CI 0.1 to 0.3) and oedema in 0.05% (n=3; CI 0.02 to 0.2). No cases of late-stage noma were detected. Multivariable analysis in the group aged 0–5 years showed having a well as the drinking water source (adjusted odds ratio (aOR) 2.1; CI 1.2 to 3.6) and being aged 3–5 years (aOR 3.9; CI 2.1 to 7.8) was associated with being a noma case. In 6–15 year olds, being male (aOR 1.5; CI 1.0 to 2.2) was associated with being a noma case and preparing pap once or more per week (aOR 0.4; CI 0.2 to 0.8) was associated with not having noma. We estimated that 129120 (CI 105294 to 1 52 947) individuals <15 years of age would have any stage of noma at the time of the survey within the two states. Most of these cases (93%; n=120 082) would be children with simple gingivitis.ConclusionsOur study identified a high prevalence of children at risk of developing advanced noma. This disease is important but neglected and therefore merits inclusion in the WHO neglected tropical diseases list.


2021 ◽  
Vol 13 (7) ◽  
pp. 115
Author(s):  
Emilia Shiwa Ashipala ◽  
Linda Ndeshipandula Lukolo

INTRODUCTION: Hypertension complications are responsible for 9.4 million deaths worldwide and among these deaths, 51 % are due to stroke and 45% are due to heart disease like heart failure. This study aims to investigate the hypertension risk factors among adult in Oshikoto region, Namibia. METHODS: A community population-based, cross- sectional survey was conducted using WHO STEPwise approach among 375 adults in Oshikoto region. Bivariate and multivariate analysis was done to determine the association between risk factors and Hypertension, based on p-value &lt;0.05. RESULTS: Overall prevalence for risk factors was: physical inactivity (25.3%), unhealthy diet (75.7%), tobacco use (9.1%), harmful use of alcohol (40.8%). 20.5% overweight with majority (85.7%) of them were females. Obesity was 9.1% in which 91.2% were females. Hypertension prevalence was 24.3%. Four percent of individuals were having two multiple risk factors for hypertension, 2.4% with four risk factors and 1.1% with more than four risk factors. Age group (OR=2.48, 95%CI=1.44-4.26, P=0.001), Obesity (OR=3.48, 95%CI=1.55-7.79, P=0.003), and overweight (OR=2.34, 95%CI=1.31-4.19, P =0.004) were significant risk factors for hypertension. CONCLUSIONS: This study revealed a high prevalence and burden of hypertension risk factors such as obesity and overweight among adults in Oshikoto region, thus, these results highlight the need for interventions to reduce and prevent those risk factors of hypertension in Oshikoto region, Namibia.


Author(s):  
Bella Nichole Kantor ◽  
Jonathan Kantor

AbstractPandemic coronavirus disease 2019 (COVID-19) may lead to significant mental health stresses, potentially with modifiable risk factors. To determine the presence of and magnitude of associations between baseline associations and anxiety and depression in the US general population, we performed an internet-based cross-sectional survey of an age-, sex-, and race-stratified representative sample from the US general population. Degrees of anxiety, depression, and loneliness were assessed using the 7-item Generalized Anxiety Disorder scale (GAD-7), the 9-item Patient Health Questionnaire (PHQ-9), and the 8-item UCLA Loneliness Scale, respectively. Unadjusted and multivariable logistic regression analyses were performed to determine associations with baseline demographic characteristics. A total of 1,005 finished surveys were returned of the 1,020 started, yielding a completion rate of 98.5% in the survey panel. The mean (SD) age of respondents was 45 (16), and 494 (48.8%) were male. Baseline demographic data were similar between those that were (n=663, 66.2%) and were not (n=339, 33.8%) under a shelter in place/ stay at home order, with the exception of sex and geographic location. Overall, 264 subjects (26.8%) met criteria for an anxiety disorder based on a GAD-7 cutoff of 10; a cutoff of 7 yielded 416 subjects (41.4%) meeting clinical criteria for anxiety. On multivariable analysis, male sex (OR 0.65, 95% CI [0.49, 0.87]) and living in a larger home (OR 0.46, 95% CI [0.24, 0.88]) were associated with a decreased odds of meeting anxiety criteria. Rural location (OR 1.39, 95% CI [1.03, 1.89]), loneliness (OR 4.92, 95% CI [3.18, 7.62]), and history of hospitalization (OR 2.04, 95% CI [1.38, 3.03]), were associated with increased odds of meeting anxiety criteria. 232 subjects (23.6%) met criteria for clinical depression. On multivariable analysis, male sex (OR 0.71, 95% CI [0.53, 0.95]), increased time outdoors (OR 0.51, 95% CI [0.29, 0.92]), and living in a larger home (OR 0.35, 95% CI [0.18, 0.69]), were associated with decreased odds of meeting depression criteria. Having lost a job (OR 1.64, 95% CI [1.05, 2.54]), loneliness (OR 10.42, 95% CI [6.26, 17.36]), and history of hospitalization (OR 2.42, 95% CI [1.62, 3.62]), were associated with an increased odds of meeting depression criteria. Income, media consumption, and religiosity were not associated with mental health outcomes. Anxiety and depression are common in the US general population in the context of the COVID-19 pandemic, and are associated with potentially modifiable factors.


Author(s):  
UBADA AQEEL ◽  
MOHAMMAD DAUD ALI ◽  
ZEENAT IQBAL ◽  
MOHD. AAMIR MIRZA

Objective: In the given study, we have carried out a survey among general population of Delhi NCR (India) for the knowledge, perceptions, and attitude toward coronavirus disease (COVID-19) and also attempted to reach to a few conclusions in the form of recommendations. Methods: A cross-sectional questionnaire based online survey (using Google Forms) was conducted between April 2020 and May 2020 to investigative knowledge, perceptions, and attitude toward COVID-19. Chi-square test was used for the computation of p-value. Results: There were total 823 respondents, with 43.01% females and 56.98% males. Around 73.74% respondents believe that it has become a social stigma. About 75.09% were of the opinion that sneezing etiquettes can help in curbing the infection. About 93.43% of study population follows the personal hygiene, 24.78% wished to get insurance coverage. Similarly, interesting data were collected over different aspects of COVID-19. Conclusions: The current pandemic is the first exposure at such a large scale to the existing population but with the progression of time, authorities and general population are collating knowledge about the same. It is to be fought at all the fronts such as medical, social, economic, and psychological. Hence, this type of survey becomes an important tool in decision making.


2020 ◽  
Author(s):  
Georges Nguefack-Tsague ◽  
Brian Bongwong Tamfon ◽  
Ismael Ngnie-Teta ◽  
Marie Nicole Ngoufack ◽  
Basile Keugoung ◽  
...  

Abstract Background: Routine Health Information Systems (RHIS) of low-income countries function below the globally expected standard, characterised by the production and use of poor-quality data, or the non-use of good quality data for informed decision making. This has negatively influenced the health service delivery and uptake. This study focuses on identifying the factors associated with the performance of RHIS of the health facilities (HF) in Yaoundé, so as to guide targeted RHIS strengthening.Methods: A HF-based cross-sectional study in the 6 health districts (HDs) of Yaoundé was conducted. HFs were chosen using stratified sampling with probability proportional to size per HD. Data were collected, entered into Microsoft Excel 2013 and analysed with IBM- SPSS version 25. Consistency of the questionnaire was measured using Cronbach’s alpha coefficient. Pearson’s chi-square (and Fisher exact where relevant) tests were used to establish relationships between qualitative variables. Associations were further quantified using unadjusted Odd ratio (OR) for univariable analysis and adjusted odds ratio (aOR) for multivariable analysis with 95% confidence interval (CI). A p-value of less than 0.05 was considered statistically significant.Results: Of 111 selected HFs; 16 (14.4%) were public and 95 (85.6%) private. Respondents aged 24-60 years with an average of 38.3±9.3 years; 58 (52.3%) males and 53(47.7%) females. Cronbach’s alpha was 0.96 (95%CI: 0.95 – 0.98, p<0.001), proving that the questionnaire was reliable in measuring RHIS performances. At univariable level, the following factors were positively associated with good performances: supportive supervision (OR = 3.03 (1.1, 8.3); p = 0.02), receiving feedback from hierarchy (OR = 3.6 (0.99, 13.2); p = 0.05), having received training on health information (OR = 5.0 (1.6, 16.0); p = 0.003), and presence of a performance evaluation plan (OR = 3.3 (1.4, 8.2), p = 0.007). At multivariable level, the only significantly associated factor was having received training on health information (aOR = 3.3 (1.01, 11.1), p = 0.04).Conclusion: Training of health staff in the RHIS favors RHIS good performance. Hence, emphasis should be laid on training and empowering staff, frequent and regular RHIS supervision, and frequent and regular feedback, for an efficient RHIS strengthening in Yaoundé.


2021 ◽  
Vol 7 (2) ◽  
pp. 170-175
Author(s):  
Hardianti Mukkadas ◽  
I Made Cristian B ◽  
Wa Ode Salma

Pregnant women who experience chronic energy deficiency (KEK) tend to give birth to LBW babies and have a greater risk of death. Objective: This study was to analyze the factors associated with the incidence of KEK in pregnant women. Methods: The study was conducted for 2 months, in 2020 at Anggaberi Health Center and Soropia Health Center in Konawe district. Design: cross sectional, quantitative data collection and secondary data. The research sample was pregnant women who were registered in the maternal cohort data, which were taken randomly as many as 115 people. Univariate data analysis was carried out descriptively to see the distribution of the values ​​of the causal factors, bivariate analysis was carried out to analyze the relationship between the causal factors and the incidence of KEK through statistics, namely Chi-square test and cross tabulation with a significance value of 0.05. The results of the study found that the factors associated with the incidence of KEK were age (p-value = 0.000), education level (p-value = 0.000), employment status (p-value = 0.000), and pregnancy weight (p-value = 0.000 ). The incidence of KEK is more likely in mothers who have characteristics such as age < 20 years and > 35 years, low education, not working and low pregnant weight. Therefore, it is hoped that an increase in food security at the family level can be socialized through providing information to preconception women through counseling, flip-charts and posters.


Author(s):  
Balasubramaniam Bharath ◽  
Sannapaneni Krishnaiah ◽  
Ahmed Imtiaz ◽  
Ramanathan V. Ramani

Background: Cataract is the leading cause of avoidable blindness in most parts of developing world, including India. The objectives were to assess cataract surgical coverage (CSC) and investigate the determinants for CSC among people aged 50 years or older in India.Methods: A population-based, cross-sectional survey was conducted to include 2023 residents aged ≥50 years old from 72 clusters of 20 districts in six states from various parts of India. Presenting visual acuity (VA), history of cataract surgery and operable cataract were assessed by trained professionals. Prevalence of CSC and factors influencing cataract surgery (CS) were studied in the multivariable logistic regression model. A two-sided p-value of <0.05 was considered to be statistically significant.Results: Cataract surgery was done in 478 (23.6%) people in both eyes. Using VA<6/18 cut-off, the CSC was estimated as 67.2% in persons. In LR model, increased age was significantly associated with increased CS (P<0.0001). The odds of prevalence of CS was significantly lower in Uttar Pradesh; adjusted Odds Ratio (OR), 0.59; (95% CI: 0.36-0.95; p=0.032) and in persons with diabetes; OR: 0.61; (95% CI: 0.38-0.94; p=0.028).Conclusions: Cataract surgical need is currently not being met in India and the increasing prevalence of diabetes is an additional major challenge in addressing the gap in CS.


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