scholarly journals Assessing seropositivity for IgG antibodies against SARS-CoV-2 in Ahmedabad city of India: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e044101
Author(s):  
Om Prakash ◽  
Bhavin Solanki ◽  
Jay K Sheth ◽  
Bhavin Joshi ◽  
Mina Kadam ◽  
...  
Keyword(s):  
Age Groups ◽  
Cross Sectional Study ◽  
Effective Vaccine ◽  
Igg Antibodies ◽  
Sectional Study ◽  
Time Zone ◽  
Cross Sectional ◽  
The People ◽  
Primary Health Centres ◽  
The Difference

ObjectivesTo study the percentage seropositivity for SARS-CoV-2 to understand the pandemic status and predict the future situations in Ahmedabad.Study designCross-sectional study.SettingsField area of Ahmedabad Municipal Corporation.ParticipantsMore than 30 000 individuals irrespective of their age, sex, acute/past COVID-19 infection participated in the serosurvey which covered all the 75 Urban Primary Health Centres (UPHCs) across 48 wards and 7 zones of the city. Study also involved healthcare workers (HCWs) from COVID-19/non-COVID-19 hospitals.InterventionsSeropositivity of IgG antibodies against SARS-CoV-2 was measured as a mark of COVID-19 infection.Primary and secondary outcomesSeropositivity was used to calculate cumulative incidence. Correlation of seropositivity with available demographic detail was used for valid and precise assessment of the pandemic situation.ResultsFrom 30 054 samples, the results were available for 29 891 samples and the crude seropositivity is 17.61%. For all the various age groups, the seropositivity calculated between 15% and 20%. The difference in seropositivity for both the sex group is statistically not significant. The seropositivity is significantly lower (13.64%) for HCWs as compared with non-HCWs (18.71%). Seropositivity shows increasing trend with time. Zone with maximum initial cases has high positivity as compared with other zones. UPHCs with recent rise in cases are leading in seropositivity as compared with earlier and widely affected UPHCs.ConclusionsThe results of serosurveillance suggest that the population of Ahmedabad is still largely susceptible. People still need to follow preventive measures to protect themselves till an effective vaccine is available to the people at large. The data indicate the possibility of vanishing immunity over time and need further research to cross verify with scientific evidences.

scholarly journals Correlation between bone turnover and metabolic markers with age and gender: a cross-sectional study of hospital information system data

2020 ◽  
Author(s):  
Shao Ju ◽  
Shaosong Zhou ◽  
Yuan Qu ◽  
bibo liang ◽  
Qing-Hong Yu ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Age And Gender ◽  
Metabolic Markers ◽  
The Difference ◽  
Highly Correlated ◽  
And Gender

Abstract Background: Bone turnover and metabolic indicators are related to age and gender. Age and gender should be matched in subjects in disease control research of bone turnover and metabolism, but strict matching of gender and age increases the difficulty and cost of the research. Therefore, the aim of this study was to solve the question of whether it is necessary to strictly match age and gender in clinical research in bone metabolism.METHODS: Patient data were extracted from the HIS of ZhuJiang Hospital, Southern Medical University. From these data, a cross-sectional study was conducted. Data relating to seven bone turnover and metabolic indicators from 1036 patients between January 2018 and October 2019 were analyzed. A total of 156 patients aged under 20 were identified and analyzed separately. RESULTS: P1NP, β-CTx and 25(OH)D were significant different in individuals younger than 20 years of age. ALP was significantly higher in those under 20 years of age and lower at age 20-39 compared with other age groups. The concentrations of Ca and P were different among the groups aged 0-19, 20-39, and 40-59 years of age groups but exhibited no difference above 60 years of age. PTH expression was not dependent on age. P1NP, β-CTx and PTH concentrations were not significantly different between the genders within the same age group. ALP was significantly different between genders within the age range 20-59 years. Ca and 25(OH)D were significantly different between the genders for those older than 60. Serum P was significantly different in the two genders for those aged 40-79. CONCLUSION: P1NP and β-CTx were highly correlated with age. If these two indictors require analysis in a case control study, the patients and controls should be strictly matched by age under 20 years. The demarcation point for ALP was 40 years of age. Ca and P were strongly recommended strict matching according to age in disease research. The difference in P1NP, β-CTx, 25(OH)D and ALP between genders depends on age differences.

scholarly journals PERBANDINGAN DENYUT NADI ANTARA PENDUDUK YANG TINGGAL DI DATARAN TINGGI DAN DATARAN RENDAH

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Ivanny Kasenda ◽  
Sylviah Marunduh ◽  
Herlina Wungouw
Keyword(s):  
Cross Sectional Study ◽  
Statistical Test ◽  
The Body ◽  
Analytic Method ◽  
Sectional Study ◽  
Mountain Area ◽  
Cross Sectional ◽  
The People ◽  
Significant Difference ◽  
The Difference

Abstract: The pulse is a pressure that is delivered in the form of a wave when the heart pumped up blood around the body.  Pulse is determined by the elasticity of blood vessels.  There are research showing the difference in pulse rate in the highlands and lowlands.  This research aimed to determine the ratio between the pulse of the people that live in the highlands (mountain area) and lowlands (coastal area). This research is an analytic method using cross sectional study.  The subjects of this research is 80 people living in the highlands and 80 people living in the lowlands.  The subjects are 18-65 years, physically and mentally healthy and they have been living at the area for 5 years.  The data were analyzed using non-parametric test Mann Whitney test. Based on the results of the Mann Whitney statistical test, it shows that there is a difference between the result  of pulse measurement  of the people living in the highlands and lowlands with asymp value. Sig. (2-tailed) α = 0:03 (α <0.05), which means that there are significant difference between highlands and lowlands. The result of this research can be concluded that there is a significant difference in the measurement of the pulse between people living in the highlands and lowlands. Keywords: Pulse, highlands, lowlands.     Abstrak: Denyut nadi adalah suatu tekanan yang dihantarkan dalam bentuk gelombang saat darah dipompa jantung ke seluruh tubuh. Denyut nadi ditentukan oleh elastisitas pembuluh darah. Terdapat penelitian yang menunjukkan adanya perbedaan denyut nadi di dataran tinggi dan dataran rendah. Penelitian ini bertujuan untuk mengetahui perbandingan denyut nadi  antara penduduk yang tinggal di dataran tinggi (daerah pegunungan) dan dataran rendah (daerah pesisir pantai). Jenis penelitian ini adalah bersifat metode analitik dengan pendekatan rancangan cross sectional study. Subjek dari penelitian ini adalah 80 orang yang tinggal di dataran tinggi dan 80 orang yang tinggal di dataran rendah. Subjek berumur 18- 65 tahun, sehat jasmani dan rohani serta tinggal menetap 5 tahun. Data di analisis menggunakan uji non parametrik yaitu uji Mann Whitney. Berdasarkan hasil uji statistik Mann Whitney menunjukkan bahwa ada perbedaan hasil pengukuran denyut nadi antara penduduk yang tinggal di dataran tinggi dan dataran rendah dengan nilai asymp. Sig. (2-tailed) α = 0.03(α < 0.05) yang berarti terdapat perbedaan yang bermakna antara dataran tinggi dan dataran rendah. Hasil penelitian ini dapat disimpulkan bahwa terdapat perbedaan yang bermakna pada pengukuran denyut nadi antara penduduk yang tinggal di dataran tinggi dan dataran rendah. Kata kunci denyut nadi, dataran tinggi, dataran rendah.

CATARACT DISEASE;

2017 ◽  
Vol 24 (09) ◽  
pp. 1420-1424
Author(s):  
Shahan Saleem ◽  
Muhammad Saleem Azeemi ◽  
Rehan Abdullah
Keyword(s):  
Risk Factors ◽  
Low Vision ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Late Presentation ◽  
Delayed Presentation ◽  
Sectional Study ◽  
Cross Sectional ◽  
The People ◽  
Study Setting

Introduction: Cataract is one of the reversible cause of decreased vision orcataract. Its highest incidence can be seen among senile and diabetics. Patients present inOpthalmology OPD with the cataract or with one of the complications of cataract. Objectives:To study the awareness of cataract disease, knowledge of risk factors and major barrierswhich result in the delayed presentation. Study Design: Cross sectional study. Setting: Itwas conducted in ophthalmology OPD. Duration: January 2017 to March 2017 (3 months).Materials & Methods: About 100 patients were selected by nonrandom purposive sampling.They were given questionnaires or direct questions were asked to fill the questionnaires.Results: 69% were males and 31% were females with age groups ranging from 35 to 95 yearsof age. Mean age was 60.90 with an SD of 11.28. About 74% of the patients were having alow educational level. For 71% of the patients, ophthalmologist was the source of informationabout his/her ailment. 57% of the people know about the nature of their disease. Regardingthe delay in presentation (36%) presented in less than 3 months after they first noticed blurringof vision. About 20% patient presented after a period of 1 year after feeling of low vision. 59%of patients knew that cataract incidence increases with age. 72% of patients knew that visioncan be restored after cataract surgery. Knowledge about the improvement of the eye conditionby microsurgery was 66%. Knowledge about the complications of cataract was estimated todecreased vision (61%), blindness (23%), pain (9%), cosmetic problems (2%), others (5%).Reasons for delay include waiting for cataract to mature (53%), financial problems (13%), toofar no people to accompany (12%), no time ( 10%), afraid (6%), don’t want to operate (4%),no reason (2%). Knowledge about the risk factors was estimated to be as diabetes (67%),hypertension (23%), others NOS (10%). Conclusion: There is a lack of awareness about thecataract disease, its complications and risk factors which result in the late presentation of thecataract patients. Patients, as well as general public, need to be educated by various means toprevent the complications of cataract and blindness.

scholarly journals Assessment of Palatal Masticatory Mucosa: A Cross-sectional Study

2013 ◽  
Vol 14 (3) ◽  
pp. 536-543 ◽  
Author(s):  
BR Anuradha ◽  
Anne Gopinadh ◽  
Bugude Shiva Shankar ◽  
Bijoy John ◽  
KA Ravi Varma Prasad ◽  
...  
Keyword(s):  
Age Groups ◽  
Young Patients ◽  
Cross Sectional Study ◽  
Wilcoxon Test ◽  
Age Group ◽  
Sectional Study ◽  
Tissue Thickness ◽  
Cross Sectional ◽  
Donor Tissue ◽  
The Difference

ABSTRACT Aim To treat mucogingival problems palatal masticatory mucosa is used as a donor material. This study aimed to determine the thickness of donor palatal mucosa and associations of age and gender in Indian subjects aged 14 to 60 years by direct clinical technique. Materials and methods Forty systemically and periodontally healthy Indian subjects (20 males; 20 females; age range of 14 to 60 years) enrolled in this study. Under local anesthesia bone sounding technique was performed at 15 defined and predetermined points. The Wilcoxon test was used to determine the difference in mucosal thickness between the age groups and between genders. Significance of the difference between individuals of different body mass index (BMI) was assessed by independent t-test. Results With mean thickness of 2.0 to 3.7 mm, the younger age group demonstrated significantly thinner donor mucosa (mean 2.8 ± 0.3 mm) than the older age group (mean 3.1 ± 0.3 mm). Within the same age group though statistically not significant; males had thicker mucosa than females. From the canine to second premolar areas and in the sites furthest from the gingival margin mucosa thickness increased. When correlated with subject's BMI, in all probed sites males demonstrated significantly a thicker mucosa than females. Within each group subjects with high BMI demonstrated thicker donor mucosa. Conclusion Current study showed that in both adult and young individuals, premolar and canine areas can be the right site for harvesting donor tissue. Even in young subjects subepithelial connective tissue (CT) graft can be harvested in adequate volume. Donor tissue thickness can be influenced by factors like genetics and race, which need to be further evaluated. Clinical significance Premolar and canine areas serve as appropriate choice to harvest palatal masticatory mucosa. Even in young patients the volume of donor tissue available is sufficient enough to consider the subepithelial CT graft procedure. Donor tissue thickness can be influenced by factors like genetics and race, which need to be further evaluated. How to cite this article Anuradha BR, Shankar BS, John B, Prasad KARV, Gopinadh A, Devi KNN. Assessment of Palatal Masticatory Mucosa: A Cross-sectional Study. J Contemp Dent Pract 2013;14(3):536-543.

scholarly journals Correlation between bone turnover and metabolic markers with age and gender: a cross-sectional study of hospital information system data

2020 ◽  
Author(s):  
Shao Ju ◽  
Shaosong Zhou ◽  
Yuan Qu ◽  
bibo liang ◽  
Qing-Hong Yu ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Age And Gender ◽  
Metabolic Markers ◽  
The Difference ◽  
Highly Correlated ◽  
And Gender

Abstract Background : Bone turnover and metabolic indicators are related to age and gender. Age and gender should be matched in subjects in disease control research of bone turnover and metabolism, but strict matching of gender and age increases the difficulty and cost of the research. Therefore, the aim of this study was to solve the question of whether it is necessary to strictly match age and gender in clinical research in bone metabolism. METHODS: Patient data were extracted from the HIS of ZhuJiang Hospital, Southern Medical University. From these data, a cross-sectional study was conducted. Data relating to seven bone turnover and metabolic indicators from 1036 patients between January 2018 and October 2019 were analyzed. A total of 156 patients aged under 20 were identified and analyzed separately. RESULTS: P1NP, β-CTx and VitD 3 were significant different in individuals younger than 20 years of age. ALP was significantly higher in those under 20 years of age and lower at age 20-39 compared with other age groups. The concentrations of Ca and P were different among the groups aged 0-19, 20-39, and 40-59 years of age groups but exhibited no difference above 60 years of age. PTH expression was not dependent on age. P1NP, β-CTx and PTH concentrations were not significantly different between the genders within the same age group. ALP was significantly different between genders within the age range 20-59 years. Ca and VitD 3 were significantly different between the genders for those older than 60. Serum P was significantly different in the two genders for those aged 40-79. CONCLUSION: P1NP and β-CTx were highly correlated with age. If these two indictors require analysis in a case control study, the patients and controls should be strictly matched by age under 20 years. The demarcation point for ALP was 40 years of age. Ca and P were strongly recommended strict matching according to age in disease research. The difference in P1NP, β-CTx, VitD3 and ALP between genders depends on age differences.

CONCENTRATION OF THE SERUM TGF-BETA1 IN HEALTHY ADULT PEOPLE

2014 ◽  
pp. 90-93
Author(s):  
Van Tuan Nguyen ◽  
Tam Vo ◽  
Bui Bao Hoang
Keyword(s):  
Transforming Growth Factor ◽  
Healthy Adult ◽  
Age Groups ◽  
Elevated Serum ◽  
Cross Sectional Study ◽  
Healthy People ◽  
Sectional Study ◽  
Transforming Growth Factor Beta1 ◽  
Cross Sectional ◽  
And Gender

Elevated serum Transforming growth factor-beta1 (TGF-beta1) levels have been linked to tissue fibrosis including chronic kidney disease. Objectives: (1) Investigate serum TGF-beta1 levels in healthy adult people and (2) Examined the relation between serum TGF-beta1 level and gender, age, body mass index (BMI). Method: A cross-sectional study. TGF-beta1 were quantified by ELISA. Results: Levels of serum TGF-beta1 in healthy people were 13,45 ± 7,17 ng/mL mL (0,59 - 33,10 ng/mL). There are no difference of serum TGF-beta1 levels between men and women, between the age groups (<40 years, 40 to < 60 years and ≥ 60 years), between BMI groups < 23 and BMI group ≥ 23. Key words: TGF-beta1, healthy people

The Prevalence of Insecticide Treated Net/malaria :cross section study (Preprint)

2019 ◽  
Author(s):  
Chanda Chalela
Keyword(s):  
Study Design ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Malaria Prevalence ◽  
Malaria Patient ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Itn Use ◽  
Structured Questionnaire

BACKGROUND ABSTRACT Introduction a study on prevalence of ITN use was carried out in Buchi community Kitwe Zambia from August to October 2019 OBJECTIVE Prevalence of ITN in BUchi METHODS Methodology: This was a cross sectional study design. A structured questionnaire was used to ascertain ownership and utilization and oral interviews, 200 households were targeted 844 individual covered across the 200 households. Data was analyzed with SPSS version 23. RESULTS ABSTRACT Introduction a study on prevalence of ITN use was carried out in Buchi community Kitwe Zambia from August to October 2019 Methodology: This was a cross sectional study design. A structured questionnaire was used to ascertain ownership and utilization and oral interviews, 200 households were targeted 844 individual covered across the 200 households. Data was analyzed with SPSS version 23. Findings: household ownership of at least an ITN was 52% and individual utilization at 37.6%, with 0.825 ITN/households and 0.195ITN /individual. Malaria prevalence of 52.4% /household and a 12.4% of the population. With 47.6% malaria patient coming from households with ITN and 60% of households with ITN have insufficient coverage.61% of malaria patient were female and 31 % male. however there was no significant relation between Gender and malaria prevalence in study area (p value was >0.05). Malaria cases distribution with age groups, 0-15yrs old represented 49.5%, 16-30 yrs., was at 27.6% and the over 30 yrs. case were at 22.9% .use of other preventive measures 23% used mosquito repellent ,others methods 1% with those not using any other methods 76%. CONCLUSIONS Conclusion The study showed clearly that malaria still poses a problem .the prevalence rate of malaria was still high 12.4% of the population and 52.4% of households. With high prevalence of malaria of 49.5% for 0-15yrs.the difference between ownership 52% and Utilization 37.6% showed that even household with ITN, the ITN were not sufficient.60% of households with ITN, the ITN were not sufficient for all occupants

scholarly journals A cross-sectional study measuring contact patterns using diaries in an urban and a rural community in South Africa, 2018

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jackie Kleynhans ◽  
Stefano Tempia ◽  
Meredith L. McMorrow ◽  
Anne von Gottberg ◽  
Neil A. Martinson ◽  
...  
Keyword(s):  
South Africa ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Rural Site ◽  
Urban Site ◽  
Contact Rate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Contact Rates ◽  
Contact Patterns

Abstract Background Describing contact patterns is crucial to understanding infectious disease transmission dynamics and guiding targeted transmission mitigation interventions. Data on contact patterns in Africa, especially South Africa, are limited. We measured and compared contact patterns in a rural and urban community, South Africa. We assessed participant and contact characteristics associated with differences in contact rates. Methods We conducted a cross-sectional study nested in a prospective household cohort study. We interviewed participants to collect information on persons in contact with for one day. We described self-reported contact rates as median number people contacted per day, assessed differences in contact rates based on participant characteristics using quantile regression, and used a Poisson model to assess differences in contact rates based on contact characteristics within age groups. We also calculated cumulative person hours in contact within age groups at different locations. Results We conducted 535 interviews (269 rural, 266 urban), with 17,252 contacts reported. The overall contact rate was 14 (interquartile range (IQR) 9–33) contacts per day. Those ≤18 years had higher contact rates at the rural site (coefficient 17, 95% confidence interval (95%CI) 10–23) compared to the urban site, for those aged 14–18 years (13, 95%CI 3–23) compared to < 7 years. No differences were observed for adults. There was a strong age-based mixing, with age groups interacting more with similar age groups, but also interaction of participants of all ages with adults. Children aged 14–18 years had the highest cumulative person hours in contact (116.3 rural and 76.4 urban). Conclusions Age played an important role in the number and duration of contact events, with children at the rural site having almost double the contact rate compared to the urban site. These contact rates can be utilized in mathematical models to assess transmission dynamics of infectious diseases in similar communities.

scholarly journals Reference values of electrographic and cardiac ultrasound parameters in Russian healthy children and adolescents

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Geraldine Landon ◽  
Isabelle Denjoy ◽  
Enora Clero ◽  
Aleksandr Silenok ◽  
Irina Kurnosova ◽  
...  
Keyword(s):  
Age Groups ◽  
Cross Sectional Study ◽  
Healthy Children ◽  
Cardiac Ultrasound ◽  
Relevant Feature ◽  
Sectional Study ◽  
Cross Sectional ◽  
Echocardiographic Parameters ◽  
Electrocardiographic Parameters ◽  
Ultrasound Parameters

AbstractBetween 2009 and 2013, a large cross-sectional study on the health consequences of the Chernobyl nuclear accident was performed in the contaminated and uncontaminated territories of the Bryansk Oblast (Russian Federation). The objective of this work was to confirm or refute a possible association between childhood cardiac arrhythmia and a chronic exposure to caesium-137. As part of this study, a large number of electrocardiographic and cardiac ultrasound parameters were collected from 18,152 children aged 2–18 years including 12,512 healthy ones not contaminated with caesium-137. It seemed therefore relevant for us to share in a second publication these medical data based on healthy and uncontaminated children with the scientific community because of the large quantities and the limited availability of such kind of data. In the present study, relating to electrocardiographic parameters, the measurements performed fully reflect the expected evolution of the paediatric electrocardiogram between 5 and 18 years of age. Thus, the median values were generally quite close to those available in the literature. In contrast, differences in the 2nd and 98th percentiles were notable and could be explained in particular by the type of equipment used, the number of subjects included in the study and racial disparities. As for echocardiographic parameters, the evolution of the measured values in age groups is consistent with what was expected considering factors such as growth. In comparison with other scientific studies that have investigated these echocardiographic parameters, some differences by age groups have been identified. The ethnic factor truly appears to be a relevant feature to consider. In view of the results, it appeared essential to the authors to approach the methodological conditions of the scientific studies already published on the topic to be truly comparable and thus to provide a reliable answer on a topic for which real expectations in terms of medical care are required.

scholarly journals Study of Maternal and Fetal Outcome among Booked and Unbooked Patients at tertiary Hospital

2020 ◽  
Vol 5 (2) ◽  
pp. 1027-1030
Author(s):  
Shanti Sunuwar Subedi ◽  
Rakina Bhansakarya ◽  
Sajjan Kumar Sharma
Keyword(s):  
Sampling Technique ◽  
Secondary Level ◽  
Tertiary Hospital ◽  
Fetal Outcome ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Spontaneous Vaginal Delivery ◽  
Significant Difference ◽  
The Difference

Introduction: To evaluate the maternal and perinatal outcome in booked and unbooked cases. Objectives: To assess the maternal and fetal outcomes in unbooked and booked patients. Methodology: This was a cross-sectional comparative study conducted in the Department of Obstetrics and Gynecology from Augustti2019 to January 2020. Using a convenient sampling technique, 204 samples were taken and cross-sectional study was done. Results: There were total 204 cases in this study;102were booked and 102 were unbooked. In this study, 85(83%) of booked cases were educated up to secondary level as compared toti65 (64%) of unbooked cases. There was no significant difference in Apgar score in 1 and 5 minute between booked and unbooked cases. More babies in the unbooked group were transferred to NICU as compared to the booked group and the difference was significant (9.8%vs 1.9%). Greater proportion of booked cases had spontaneous vaginal delivery (81.3% vs 59.8%) and complications like preterm delivery, anemia, preeclampsia/ eclampsia, complicated labor and puerperal sepsis was also less in the booked group. Conclusions: The study showed that unbooked mothers and their newborns had higher chance of having complications.

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