scholarly journals Sports-related concussions and subconcussive impacts in athletes: incidence, diagnosis, and the emerging role of EPA and DHA

2020 ◽  
Vol 45 (8) ◽  
pp. 886-892
Author(s):  
Cody A.C. Lust ◽  
Margo Mountjoy ◽  
Lindsay E. Robinson ◽  
Jonathan M. Oliver ◽  
David W.L. Ma
Keyword(s):  
Structural Damage ◽  
Brain Injuries ◽  
Professional Sports ◽  
Experimental Models ◽  
The Body ◽  
Pufa Supplementation ◽  
Epa And Dha ◽  
Biomechanical Force

Sports-related concussions (SRC) are traumatic brain injuries induced as the result of a biomechanical force to the body that temporarily impair neurological functions. Not all traumatic impacts reach the threshold necessary to produce concussive symptoms; however, the culmination of these events is known as a subconcussive impact (SCI). Athletes who have been diagnosed with a SRC or those who accumulate multiple SCI have exhibited structural damage to the brain, impairments to learning and memory, and an increase in depressive symptoms. This area is rapidly evolving, and current clinical definitions of injury, diagnosis, and treatment of SRC and SCI are reviewed. In tandem, there is also growing research examining the role of nutrition in brain injuries, focusing primarily on n-3 polyunsaturated fatty acids (PUFA). The potential role of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in reducing inflammation and promoting recovery following brain injury are also reviewed. Overall, advancements in the evaluation of SRC and SCI coupled with n-3 PUFA supplementation show promise in the management of brain injuries, leading to better long-term health outcomes for athletes. Novelty SRC have garnered widespread attention due to the growing body of reported prevalence in youth and professional sports. Current definitions and protocol(s) for diagnosing SRC and SCI have improved, but still require further evaluation. n-3, EPA and DHA, reduce inflammation and promote recovery following brain injuries in experimental models.

Neuroprotective Role of Nutritional Supplementation in Athletes

2021 ◽  
Vol 14 ◽  
Author(s):  
Supriya Mishra ◽  
Vikram Jeet Singh ◽  
Pooja A Chawla ◽  
Viney Chawla
Keyword(s):  
Neurodegenerative Disorders ◽  
Brain Injuries ◽  
Recovery Process ◽  
Traumatic Brain Injuries ◽  
Omega 3 ◽  
Long Run ◽  
Pathological Mechanism ◽  
Injury Recovery

Background: Neurodegenerative disorders belong to different classes of progressive/chronic conditions that affect the peripheral/central nervous system. It has been shown through studies that athletes who play sports involving repeated head trauma and sub-concussive impacts are more likely to experience neurological impairments and neurodegenerative disorders in the long run. Aims: The aim of the current narrative review article is to provide a summary of various nutraceuticals that offer promise in the prevention or management of sports-related injuries, especially concussions and mild traumatic brain injuries. Methods: This article reviews the various potential nutraceutical agents and their possible mechanisms in providing a beneficial effect in the injury recovery process. A thorough survey of the literature was carried out in the relevant databases to identify studies published in recent years. In the present article, we have also highlighted the major neurological disorders along with the associated nutraceutical(s) therapy in the management of disorders. Results: The exact pathological mechanism behind neurodegenerative conditions is complex as well as idiopathic. However, mitochondrial dysfunction, oxidative stress as well as intracellular calcium overload are some common reasons responsible for the progression of these neurodegenerative disorders. Owing to the multifaceted effects of nutraceuticals (complementary medicine), these supplements have gained importance as neuroprotective. These diet-based approaches inhibit different pathways in a physiological manner without eliciting adverse effects. Food habits and lifestyle of an individual also affect neurodegeneration. Conclusion: Studies have shown nutraceuticals (such as resveratrol, omega-3-fatty acids) to be efficacious in terms of their neuroprotection against several neurodegenerative disorders and to be used as supplements in the management of traumatic brain injuries. Protection prior to injuries is needed since concussions or sub-concussive impacts may trigger several pathophysiological responses or cascades that can lead to long-term complications associated with CNS. Thus, the use of nutraceuticals as prophylactic treatment for neurological interventions has been proposed.

scholarly journals HYPERMNESIA EUPHORIA OR ANY OTHER DESIRABLE FROM THE POINT OF VIEW OF THE CONSUMER, A PSYCHOTROPIC EFFECT - FIRST AND LEADING ELEMENT IN THE OCCURRENCE AND PRESERVATION OF THE BODY’S DEPENDENCE ON PSYCHOACTIVE FACTORS

2017 ◽  
Vol 9 (3) ◽  
pp. 40-46
Author(s):  
D G Baitubayev ◽  
M D Baitubayeva
Keyword(s):  
Substance Dependence ◽  
Point Of View ◽  
The Body ◽  
Long Term Memory ◽  
Vegetative Nervous System ◽  
Term Memory ◽  
Psychotropic Effect

The work shows the role of the vegetative nervous system (VNS) in the functioning of long-term memory, identity mechanisms of long-term memory in the human evolutionary adaptation and substance dependence. It is shown that, depending on the substance of the body are states like pro- gressive adaptation, that the bodycondition, depending on the chemical and psychogenic psychoactive- factors state of the same circle. It proposed the creation of a branch of medicine that combines study of the dependence of the organism, both on the chemical and psychoactive psychogenic factors. Given the classification of psychoactive factors.Onomastics formulated definitions of terminology changes and additions to be used in a new branch of medicine. Proposed allocation of the International Classifica- tion of diseases separate chapter for the classification of states like progressive adaptation of the body depending on psychoactive factors.

scholarly journals The Long and Short of It: The Role of Telomeres in Fetal Origins of Adult Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Stephanie E. Hallows ◽  
Timothy R. H. Regnault ◽  
Dean H. Betts
Keyword(s):  
Intrauterine Growth Restriction ◽  
The Body ◽  
Premature Aging ◽  
Fetal Origins ◽  
Maternal Malnutrition ◽  
Adult Disease ◽  
Increased Risk

Placental insufficiency, maternal malnutrition, and other causes of intrauterine growth restriction (IUGR) can significantly affect short-term growth and long-term health. Following IUGR, there is an increased risk for cardiovascular disease and Type 2 Diabetes. The etiology of these diseases is beginning to be elucidated, and premature aging or cellular senescence through increased oxidative stress and DNA damage to telomeric ends may be initiators of these disease processes. This paper will explore the areas where telomere and telomerase biology can have significant effects on various tissues in the body in IUGR outcomes.

scholarly journals COVID-19: Nutrition to Boost Immune System to Fight Infection

2020 ◽  
pp. 1-4
Author(s):  
Syed M. Shahid ◽  
◽  
Muhammad Jawed ◽  
Keyword(s):  
Immune System ◽  
Fruits And Vegetables ◽  
Daily Intake ◽  
The Body ◽  
Food And Nutrition ◽  
Working Together ◽  
Scientific Significance ◽  
Global Population

The immunity and immune system functions to fight against infections are significantly impacted by inappropriate food and nutrition. Long term malnutrition is universally considered as the leading cause of immune system deficiency. A substantial proportion of the global population does not meet the recommended daily intake of nutrients. The COVID-19 pandemic has focused attention on the role of the immune system, with health scientists and nutritionists urging people to take supplements and/or eat particular foods (nutrients) to super-charge their immune systems.The immune system is the most complex system of human body. This system is made up of a complex network of structural and functional units like cells, molecules, tissues and organs all working together to safeguard the body as a whole.This precise review provides a chance to go through the efficacy, efficiency and scientific significance of nutritional components and relevant food (especially fruits and vegetables). This will help you keep appropriate food items in your daily meals so that you can get a progressive increment in your body’s defence mechanisms and immunity to fight appropriately against COVID-19. This will also help to decrease your risk for catching the viral infection and/or reducing the chances of having complications from COVID-19.

scholarly journals Urban Mining of e-Waste and the Role of Consumers

2021 ◽  
Author(s):  
Dimitris Georgantzis Garcia ◽  
Sven Kevin van Langen
Keyword(s):  
Consumer Behaviour ◽  
Final Section ◽  
Keyword Search ◽  
Survey Methods ◽  
The Body ◽  
Urban Mining ◽  
Closed Loop Supply Chains

This chapter adds to the body of literature on the Circular Economy (CE), urban mining, and their intersection with consumer behaviour, by first providing a review of existing and emergent EU regulations aimed towards enhancing the collection rate of household WEEE. The fast growth of the EEE waste stream and its potential for Urban Mining as well as the inability of WEEE collection to keep up with the growth of the EEE industry is showcased with statistical data. The final section critically analyses the literature the intersection between consumer behaviour and closed-loop supply chains for EEE, identified through a systematic keyword search to ensure replicability. The findings point at a lack of theoretical, methodological and product-case heterogeneity among the identified sources, with most of them employing the Theory of Planned Behaviour and survey methods and focusing on mobile phones or general WEEE. While the literature suggests important behavioural differences across EEE categories, this was not representatively explored. The final section contributes to filling this gap by developing a taxonomy of EEE categories based on characteristics that may predispose consumer behaviour. The identified dimensions are: size, involvement, long-term reliability expectations, value type, internet access, multifunctionality, the quality of being outdated and social meaning.

scholarly journals Potential therapeutic manipulations of the CXCR3 chemokine axis for the treatment of inflammatory fibrosing diseases

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 1197
Author(s):  
Morgan K. Groover ◽  
Jillian M. Richmond
Keyword(s):  
Wound Healing ◽  
Tumor Metastasis ◽  
Ex Vivo ◽  
Experimental Models ◽  
The Body ◽  
Human Tissues ◽  
Inflammatory Processes ◽  
Opinion Article ◽  
Different Tissues

Chemokines play important roles in homeostasis and inflammatory processes. While their roles in leukocyte recruitment are well-appreciated, chemokines play additional roles in the body, including mediating or regulating angiogenesis, tumor metastasis and wound healing. In this opinion article, we focus on the role of CXCR3 and its ligands in fibrotic processes. We emphasize differences of the effects of each ligand, CXCL9, CXCL10 and CXCL11, on fibroblasts in different tissues of the body. We include discussions of differences in signaling pathways that may account for protective or pro-fibrotic effects of each ligand in different experimental models and ex vivo analysis of human tissues. Our goal is to highlight potential reasons why there are disparate findings in different models, and to suggest ways in which this chemokine axis could be manipulated for the treatment of fibrosis.

Aviation as a specific field for issuing opinions by court experts

2015 ◽  
Vol 290 ◽  
pp. 109-114
Author(s):  
Robert Konieczka ◽  
Keyword(s):  
Law Enforcement ◽  
Initial Phase ◽  
Expert Witness ◽  
The Body ◽  
Criminal Proceedings ◽  
Aircraft Accidents ◽  
Legal Proceedings ◽  
State Commission

This article attempts to provide a synthetic presentation of aviation as an area amenable to issuing opinions by court-appointed experts in the field. It presents basic issues concerning the participation of aviation experts in legal proceedings related to aviation, especially to air accidents. As indicated, aviation is an interdisciplinary industry employing highly diversified equipment. Subsequently, the article illustrates the role of an aviation expert in the proceedings conducted by law enforcement and judicial authorities, related to accident occurrence and other infringements of aviation law regulations. Basic issues that may be brought to the attention of the body conducting the proceedings are defined. The article emphasizes the uniqueness of the objectives of criminal proceedings and the activities aimed at determining the cause of an accident undertaken by the State Commission on Aircraft Accidents lnvestigation. The author’s long-term practice as an aviation expert witness was exploited to familiarize the reader with aviation-related issues, which can be helpful in conducting a pre-trial procedure, in particular its initial phase.

Equine obesity and the role of the veterinary nurse

UK-Vet Equine ◽  
2021 ◽  
Vol 5 (6) ◽  
pp. 265-268
Author(s):  
Clarissa Seeley ◽  
Stella Chapman
Keyword(s):  
Body Condition ◽  
The Body ◽  
Body Condition Scoring ◽  
Client Education ◽  
Inherent Problem ◽  
Equine Obesity ◽  
The Individual ◽  
The Uk

Equine obesity is defined as a medical disease in which excess body fat has accumulated to such an extent that it has an adverse effect on the general health of the horse. Obesity is a cause for concern, with one-third of the equine population in the UK being regarded as obese, although owner recognition of obesity in horses is an inherent problem, with many underestimating the body condition or weight of their horse. This is further complicated by the fact that with larger framed horses, or horses that are already overweight, assessing body condition is more difficult. There are a number of ways to assess body condition and the most practical means of regular assessment is body condition scoring, although this is regarded as subjective. As with many diseases and disorders, the cause of obesity is multifactorial. However, the most common reason for a horse to become obese is overfeeding, coupled with a lack of exercise. Obesity can be addressed with client education and veterinary nurses can provide advice on weight management programmes. However, these need to be tailored to the individual horse and owners need to recognise that they are entering into a long-term commitment.

scholarly journals FructationIn Vivo: Detrimental and Protective Effects of Fructose

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
H. M. Semchyshyn
Keyword(s):  
Oxidative Stress ◽  
Side Effects ◽  
Experimental Models ◽  
Oxygen Species ◽  
Protective Effects ◽  
Compelling Evidence ◽  
Animal Tissues

There is compelling evidence that long-term intake of excessive fructose can have deleterious side effects in different experimental models. However, the role of fructosein vivoremains controversial, since acute temporary application of fructose is found to protect yeast as well as animal tissues against exogenous oxidative stress. This review suggests the involvement of reactive carbonyl and oxygen species in both the cytotoxic and defensive effects of fructose. Potential mechanisms of the generation of reactive species by fructose in the nonenzymatic reactions, their implication in the detrimental and protective effects of fructose are discussed.

scholarly journals Mental health and politics since the eurozone crisis: The role of mental health professionals

2019 ◽  
Vol 62 ◽  
pp. 28-29 ◽  
Author(s):  
Isabel M. Perera
Keyword(s):  
Mental Health ◽  
Economic Crisis ◽  
Mental Health Professionals ◽  
Health Professionals ◽  
The Body ◽  
Generalized Anxiety ◽  
Eurozone Crisis ◽  
The Mind

Abstract Some of the most immediate health effects of the 2008 economic crisis concerned the mind, not the body. Rates of generalized anxiety, chronic depression, and even suicide spiked in many European societies. This viewpoint highlights the role of mental health professionals in responding to this emergency, and argues that their sustained mobilization is necessary to its long-term resolution.

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