scholarly journals INNOVATION, IMITATION AND ENTREPRENEURSHIP

2006 ◽  
Vol 51 (02) ◽  
pp. 147-173 ◽  
Author(s):  
GRACE LI ANN YONG ◽  
KONG WENG HO

This paper analyzes the gradual shift in the technological paradigm of an economy as it approaches the world technology frontier. The model developed in this paper consists of firms which employ skilled workers as an important input in technological advancement, but the novel feature here is the entrepreneur, who is the brain of technological progress. The entrepreneur has to decide to undertake either imitative or innovative activities, of which decision both affects and is affected by the country's distance to frontier. Specifically, the entrepreneur needs to have a minimum ability threshold level in order to carry out innovation. This endogenous threshold level falls as the economy moves closer to the technological frontier, enabling more entrepreneurs to be engaged in an innovation-based strategy, and consequently, moving the economy from a technological structure that is based on imitation of foreign technologies to one where domestic innovation dominates. The transitional dynamics of the model shows that there exists a steady state distance from the world frontier that countries will eventually converge to. We also find that it is possible for countries under certain conditions, to be trapped in a regime carrying out only imitation of world technologies.

2020 ◽  
Vol 8 (3) ◽  
pp. 1
Author(s):  
Seidu A. Richard ◽  
Nana Y.B Manaphraim ◽  
Nii Korley Kortei

Aflatoxins B1(AFB1) is an ancillary lethal metabolite archetypally spawned by Aspergillus flavus as well as A. parasiticus mostly found all over the world but more in tropic and humid regions. AFB1 has been isolated is almost all food products. The isolation of AFB1 in humans was demonstrated using human fluid like urine, serum as well as breast milk. Also, AFB1 was isolated in human placenta in pregnant women. ELISA is extremely sensitive in detecting AFB1. AFB1 was capable of compromising the activities of the blood-brain barrier (BBB). AFB1 was capable of triggering peripheral and central nervous degeneration. Acute central nervous system (CNS) symptoms like coma, cerebral edema as well as death has been observed in AFB1 exposure to the brain. Also, symptoms of brain destruction such as dullness, restlessness, muscle tremor, convulsions, loss of memory, epilepsy, idiocy, loss of muscle coordination, and abnormal sensations have been associated with deficiencies of these neurotransmitter during AFB1exposure. AFB1 was capable of influencing the end products of proteins as well as amino acid metabolism leading to hyper-ammonemia which easily cross the BBB to trigger the synthesis of glutamate neurotransmitters which are cytotoxic to the brain cells and causes encephalopathy. Glutathione (GHS) depletion resulted in destruction to critical cellular components such as DNA, lipids and proteins via the 8,9 epoxides of AFB1.This review therefore elucidates the novel neurotoxic and neuroimmunotoxic roles of AFB1 on the CNS.


2018 ◽  
Vol 8 (6) ◽  
pp. 131
Author(s):  
Saba Zaidi ◽  
Mehwish Sahibzada ◽  
Saman Salah ◽  
Anisa Tul Mehdi ◽  
Durdana Rafique

Technological advancement has made the world a complex arena of day to day transforming phenomenon. In such a complex and technologically progressive world nothing is static instead things have become technology oriented. The socio-historical phenomena like orientalism and imperialism are also not free from technological progress. Similarly, literature of the contemporary times has become Postmodernist for it now aims to represent the current human experiences. The quality of the Postmodernist literature is to represent and dismantle the socio-cultural constructions that use to perpetuate control and power. The objective of this research is twofold; it has projected the world of technological progress and innovation through the analysis of the selected Post-cyberpunk novel Accelerando (2005) by Charles Stross, The Windup Girl (2009) by Paolo Bacigalupi and The Rapture of the Nerds (2012) by Cory Doctorow and Charles Stross. Socio-Cognitive analysis (van Dijk, 2008) has projected the linguistic discursive analysis of techno-colonialism in order to answer the research questions. The study has also introduced Post-cyberpunk as the genre of Postmodernist twenty-first century literature. The findings of the research have suggested that the selected Post-cyberpunk novels have not only represented techno-colonialism but they have also characterized the impact and influence of the techno-colonizers throughout the world.


2020 ◽  
Vol 13 ◽  
pp. 117864692097824
Author(s):  
Chenthamara Dhrisya ◽  
Murugan Prasathkumar ◽  
Robert Becky ◽  
Salim Anisha ◽  
Subramaniam Sadhasivam ◽  
...  

Fear is an indispensable characteristic of any infectious disease, and the alarm will be further amplified when the infection spreads uncontrollable, unpredictable, and global. The novel corona virus (SARS CoV-2) lead Covid-19, has been declared as a global emergency by WHO as it has affected millions of people with a high mortality rate. The non-availability of medicine for Covid-19 and the various control measures such as social distancing, self-isolation, house quarantine, and the new normal implementation by different nations across the world to control the spread of Covid-19 made people vulnerable to fear and anxiety. As a result, considerable number of Covid-19-related suicidal deaths has been reported across the world during this pandemic. There have been several studies which describe the psychosocial aspects of suicidal ideation. However, the research on the biological aspects of suicidal ideation/suicidal risk factors that are related to pandemic are unreported. Hence this review article is intended to provide a comprehensive analysis of suicidal deaths during Covid-19 and also aimed to addresses the possible link between suicidal ideation and different factors, including psycho-social, behavioral, neurobiological factors (proximal, distal, and inflammatory) and immunity. The alterations in glutamatergic and GABAergic neurotransmitters had upregulated the GABARB3, GABARA4, GABARA3, GABARR1, GABARG2, and GAD2 gene expressions in suicidal victims. The changes in the Kynurenine (KYN) pathway, Hypothalamus-Pituitary-Adrenal axis (HPA axis) hyperactivation, and dysregulation of serotonin biosynthesis would significantly alter the brain chemistry in people with suicide ideation.


2012 ◽  
Vol 21 (26) ◽  
pp. 59-70
Author(s):  
Maxim Shadurski

Utopian thought, conventionally seeking to harmonize the world, witnessed an essential revision in the 20th century. This period of grand political and social upheavals, world wars, an arms race, scientific and technological progress, ecological concerns, and globalization radically undermined mankind’s faith in the humanistic potential of utopian projects. However, in Aldous Huxley’s writings, the intention to summon up a utopian experiment superseded any agonies of doubt about programmes of social reconstruction. Huxley turned to utopia when mass distrust in the constructive impulse of the genre had become notable in the socio-cultural climate. In Huxley’s last novel, Island (1962), “the poetry of silence” can be seen to render an optimistic response to the unholy state of the world.This article examines the novel’s lyrical interspersions, which arguably create a specific concept of silence through a series of thematic explorations comprising the ideas of noiselessness, speechlessness, and peace. The idea of noiselessness endorses a form of overcoming the world’s invincible cacophony. This kind of omnipotent dissonance can be diminished only by a supernatural power which integrates man’s disparate relationships with the universe. Like Nature for Wordsworth, Huxley’s image of the noiseless movement of the world unveils an image of unity to those who bring with them “a heart that watches and receives.” The idea of speechlessness surfaces in the lyrical fragments of the novel that touch upon intuition. Intuitive discoveries lie at the heart of a religion unfettered from dogma, and allow access to the perennial wisdom which becomes “suddenly visible” through the act of elevation to the summit of the universe. The idea of peace is placed outside the conventional frame of existential discrepancies. For this reason, the image of Shiva is meant to transcend the opposition of life and death. As long as Shiva dances simultaneously in all the planes of reality, the Palanese can learn from him how to exist in non-attachment. The acceptance of the world’s entropic progression checked by the poetry of silence leads the protagonist to a spiritual awakening and stirs his empathy for the utopian order realized in Pala.The poetry of silence embraces the beauty of the world which comes into existence from what Huxley calls a “pregnant emptiness.” The mystery of this creation cannot be subjected to any scientific, philosophical, or even theological systems of reference. One may only sense this mystery without reasoning. Wisdom converges with the skyin emptiness, dubbed “the womb of love,” and creates a universe from the poetry of silence. In Island, utopian thought, traditionally focusing on the regular patterns of a perfect society and state, attains a mystical profile promoted by the poetry of silence.


Author(s):  
Adedapo AA ◽  
Demokun BO

With the rapid technological advancement, which the world is now witnessing, and the continuous transformation of the world economies through globalization, there is a great pressure than before in many countries to develop their vocational education system to meet their developmental needs. That is why it is important for schools to prepare and supply future worker with appropriate knowledge and skills to enhance their productivity and therefore promote economic growth. Skills acquisition has sometimes become a tool for addressing the economic, political and social stability of some nations. As a result of rising unemployment, lack of skilled workers, high dropout rate, and the changing demographic nature of the workforce, these have placed the issue of education reform agenda high in many countries. It will further enhance the education implementers to focus on possible policies that will encourage skills acquisition among the youths in Ibadan North local government. Skills acquisition helps youths develop a positive attitude towards work and labour helps youths to be self-reliant and independent. A skill-acquired man is a self-employed man. A self-employed person can never go hungry because the skill he acquired provides food for him/her on a daily basis. But one who lacks skill acquisition will find it difficult to be self-employed because he/she has nothing to offer. Skill acquisition program is perceived as one of the crucial element in enhancing self-employment and economic productivity. It is vital for educational institutions to provide the resources needed to teach skill acquisition in schools. It is significant for parents, educators and even the government to note the relevance of scholars studying this skills in school because it provides students with life skills to become productive entrepreneurs, as it breeds creative and innovative ideas. In the long run, it impacts on the economy will be tremendously felt and will also increase personal freedom.


Sains Insani ◽  
2018 ◽  
Vol 1 (1) ◽  
pp. 69-77
Author(s):  
Intan Suria Hamzah ◽  
Sity Daud

Malaysia experienced a number of the entry of foreigners in the world, mainly as low-skilled workers. Malaysia has been experiencing shortage of workers in main sectors such as construction, agriculture, industrial and service. Foreign workers are workers came from other countries who come to work in Malaysia for a certain period, they are also known as economic’s workers. The study found that foreign workers give benefits for country development process in variuos sectors but with their numbers growing and reaching millions of peoples were disturbing economy and local communities.Keywords: Foreign worker, demand, economy, PATI, crime, security Abstrak: Malaysia mengalami jumlah kemasukan warga asing yang besar di dunia, terutamanya sebagai buruh berkemahiran rendah. Malaysia telah mengalami masalah kekurangan buruh dalam sektor-sektor utama negara seperti pembinaan, perladangan, perindustrian dan perkhidmatan. Pekerja asing atau buruh asing merupakan pekerja yang berasal dari negara luar yang datang bekerja di Malaysia bagi sesuatu tempoh tertentu, ianya juga dikenali sebagai buruh ekonomi. Hasil kajian, mendapati pekerja asing telah membawa manfaat dalam proses pembangunan negara Malaysia dalam pelbagai sektor namun begitu dengan jumlah mereka yang semakin meningkat dan mencecah jutaan orang telah mengganggu-gugat ekonomi dan masyarakat tempatan.Kata kunci: Pekerja asing, permintaan, ekonomi, PATI, jenayah, keselamatan.


Author(s):  
Jesse Schotter

Hieroglyphs have persisted for so long in the Western imagination because of the malleability of their metaphorical meanings. Emblems of readability and unreadability, universality and difference, writing and film, writing and digital media, hieroglyphs serve to encompass many of the central tensions in understandings of race, nation, language and media in the twentieth century. For Pound and Lindsay, they served as inspirations for a more direct and universal form of writing; for Woolf, as a way of treating the new medium of film and our perceptions of the world as a kind of language. For Conrad and Welles, they embodied the hybridity of writing or the images of film; for al-Hakim and Mahfouz, the persistence of links between ancient Pharaonic civilisation and a newly independent Egypt. For Joyce, hieroglyphs symbolised the origin point for the world’s cultures and nations; for Pynchon, the connection between digital code and the novel. In their modernist interpretations and applications, hieroglyphs bring together writing and new media technologies, language and the material world, and all the nations and languages of the globe....


2020 ◽  
Vol 26 (2) ◽  
pp. 350-356
Author(s):  
Anca Sîrbu

AbstractWith the rapid onset of an unprecedented lifestyle due to the new coronavirus COVID-19 the world academic scene was forced to reform and adapt to the novel circumstances. Although online education cannot be regarded as a groundbreaking endeavour anymore in the21st century, its current character of exclusivity calls for deeper understanding of, and a sharper focus on the “end-consumer” thereof as well as more cautious procedures to be exercised while teaching. While millennials are no longer thought of as being born with a silver spoon in their mouth but with an iPad or any sort of device in their hand (irrespective of their social status), adults are more hesitant when coerced to alter course unexpectedly and turn to new methods of attaining their learning goals. This is why proper communicative approaches need to be thoroughly considered by online instructors. This article aims at presenting teachers with a set of strategies to employ when the beneficiaries of online academic education are adult learners.


2016 ◽  
Vol 1 (3) ◽  
pp. 141
Author(s):  
Rana Sağıroğlu

Margaret Atwood, one of the most spectacular authors of postmodern movement, achieved to unite debatable and in demand critical points of 21st century such as science fiction, postmodernism and ecocriticism in the novel The Year of The Flood written in 2009. The novel could be regarded as an ecocritical manifesto and a dystopic mirror against today’s degenerated world, tending to a superficial base to keep the already order in use, by moving away from the fundamental solution of all humanity: nature. Although Atwood does not want her works to be called science fiction, it is obvious that science fiction plays an introductory role and gives the novel a ground explaining all ‘why’ questions of the novel. However, Atwood is not unjust while claiming that her works are not science fiction because of the inevitable rapid change of 21st century world becoming addicted to technology, especially Internet. It is easily observed by the reader that what she fictionalises throughout the novel is quite close to possibility, and the world may witness in the near future what she creates in the novel as science fiction. Additionally, postmodernism serves to the novel as the answerer of ‘how’ questions: How the world embraces pluralities, how heterogeneous social order is needed, and how impossible to run the world by dichotomies of patriarchal social order anymore. And lastly, ecocriticism gives the answers of ‘why’ questions of the novel: Why humanity is in chaos, why humanity has organized the world according to its own needs as if there were no living creatures apart from humanity. Therefore, The Year of The Flood meets the reader as a compact embodiment of science fiction, postmodernism and ecocriticism not only with its theme, but also with its narrative techniques.


2020 ◽  
Author(s):  
Micael Davi Lima de Oliveira ◽  
Kelson Mota Teixeira de Oliveira

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.


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