Facile One-Step Dialysis Strategy for Preparation of Porous Silica Nanoparticles with Rough Surface

NANO ◽  
2020 ◽  
Vol 15 (03) ◽  
pp. 2050038
Author(s):  
Zhe Chen ◽  
Jiaqiong Xu ◽  
Xuechen Xiang ◽  
Dongfang Ren ◽  
Ning Chen ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Rough Surface ◽  
Mesoporous Silica Nanoparticles ◽  
Porous Silica ◽  
Catalytic Performance ◽  
Ammonia Solution ◽  
Type Iv ◽  
Organic Surfactant ◽  
One Step ◽  
Adsorption Desorption

In this study, porous silica nanoparticles were fabricated in the absence of organic surfactant template at room temperature by a facile one-step dialysis method. By using a dialysis system comprising an ammonia solution as the dialysate, a series of porous silica nanoparticles with a rough surface (e.g., raspberry-like) were obtained by the initiation of a homogeneous ternary tetraethylsilicate-water-ethanol system with different ammonia solution concentrations. The specific surface area and pore volume of porous nanoparticles were regulated by changing the dialysate concentrations. N2 adsorption–desorption measurements revealed that the porous silica nanoparticles owned both mesopores and micropores and exhibited a type IV isotherm, hence, these nanoparticles can be used as mesoporous silica nanoparticles (MSNs). The Au@MSN nanocomposite can be used as a catalyst for the typical reduction of 4-nitrophenol to 4-aminophenol by NaBH4 and exhibited excellent catalytic performance.

scholarly journals Synthesis and Testing of Functional Mesoporous Silica Nanoparticles for Removal of Cr(VI) Ions From Water

2020 ◽  
Vol 11 (2) ◽  
pp. 8599-8607
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Porous Silica ◽  
Nitrogen Adsorption ◽  
Attenuated Total Reflection ◽  
Functionalized Mesoporous Silica ◽  
Adsorption Removal ◽  
Transmission Electron ◽  
Adsorption Desorption

This work reports a reliable and reproducible synthesis and in situ functionalization protocol for the synthesis of amino-functionalized mesoporous silica nanoparticles (MSNs). The porous amino-functional (pSiO2-NH2) nanoparticles were fully characterized by high-resolution transmission electron microscopy (TEM), X-ray diffraction (XRD), Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) and nitrogen adsorption-desorption (BET) analyses. The size of the particles was in the range of 80-200 nm with a specific surface area (SSA) of 721 m2 g-1, and the pore diameter was 31Å. The pSiO2-NH2 nanoparticles were tested for their efficiency in removing Cr(VI) ions from water. Almost quantitative removal of the ions was achieved by using the particles just within two hours. The adsorption efficiency of the particles was about 50 mg g-1. The synthesized porous silica particles can be repeatedly used as nano adsorbent for the adsorption removal of Cr(VI) ions from water. The nanoparticles can be potentially used for the selective capture, removal, and recovery of various other metal ions that can be complexed by amino groups.

scholarly journals Structural and Oxidative Properties of Manganese Incorporated Mesostructure Silica for Methane Oxidation

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Rihem Dardouri ◽  
Anis Gannouni ◽  
Mongia Saïd Zina
Keyword(s):  
Ion Exchange ◽  
Methane Oxidation ◽  
Crystalline Phase ◽  
Synthesis Method ◽  
Porous Silica ◽  
Chemical Properties ◽  
Active Phase ◽  
Catalytic Performance ◽  
Adsorption Desorption ◽  
Mcm 41

Manganese catalysts containing templated mesostructured porous silica were prepared using different methods of preparation, namely, the direct hydrothermal (DHT), solid-state ion exchange (SSI), template ion exchange (TIE), and impregnation (Imp) methods. The physical-chemical properties of materials were characterized by X-ray diffraction (XRD), N2 adsorption-desorption, FT-IR, TEM, EDX, UV-Vis, EPR, and H2 TPR techniques. The results of this study indicate that the obtained catalysts retained their hexagonal mesopore structure after introducing Mn into MCM-41. On the contrary, the crystalline phase of manganese oxide was stabilized on the external surface and inside the mesoporosity of the MCM-41 and seems to be dependent on the synthesis method used. Catalytic performances of synthesized materials were then investigated in methane oxidation at atmospheric pressure. The results showed that the metal loading and catalysts synthesis procedure influence the catalytic performance of the obtained materials. Moreover, the activity of the catalyst depends on the crystalline phase and particularly on the environment of the active phase.

scholarly journals The Engineering of Porous Silica and Hollow Silica Nanoparticles to Enhance Drug-loading Capacity

Processes ◽  
2019 ◽  
Vol 7 (11) ◽  
pp. 805 ◽  
Author(s):  
Ngoc-Tram Nguyen-Thi ◽  
Linh Phuong Pham Tran ◽  
Ngoc Thuy Trang Le ◽  
Minh-Tri Cao ◽  
The-Nam Tran ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Loading ◽  
Sol Gel ◽  
Porous Silica ◽  
High Capacity ◽  
X Ray Diffraction ◽  
Transmission Electron ◽  
Hollow Mesoporous Silica ◽  
Hollow Silica Nanoparticles

As a promising candidate for expanding the capacity of drug loading in silica nanoplatforms, hollow mesoporous silica nanoparticles (HMSNs) are gaining increasing attention. In this study, porous nanosilica (PNS) and HMSNs were prepared by the sol-gel method and template assisted method, then further used for Rhodamine (RhB) loading. To characterize the as-synthesized nanocarriers, a number of techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM), nitrogen absorption-desorption isotherms, dynamic light scattering (DLS), thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) were employed. The size of HMSN nanoparticles in aqueous solution averaged 134.0 ± 0.3 nm, which could be adjusted by minor changes during synthesis, whereas that of PNS nanoparticles was 63.4 ± 0.6 nm. In addition, the encapsulation of RhB into HMSN nanoparticles to form RhB-loaded nanocarriers (RhB/HMSN) was successful, achieving high loading efficiency (51.67% ± 0.11%). This was significantly higher than that of RhB-loaded PNS (RhB/PNS) (12.24% ± 0.24%). Similarly, RhB/HMSN also possessed a higher RhB loading content (10.44% ± 0.02%) compared to RhB/PNS (2.90% ± 0.05%). From those results, it is suggested that prepared HMSN nanocarriers may act as high-capacity carriers in drug delivery applications.

scholarly journals Macrophage-like THP-1 cells show effective uptake of silica nanoparticles carrying inactivated diphtheria toxoid for vaccination

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Xinyue Huang ◽  
Danielle Paixão Cavalcante ◽  
Helen E Townley
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Sol Gel ◽  
Porous Silica ◽  
Diphtheria Toxoid ◽  
Similar Distribution ◽  
Antigen Delivery ◽  
Before And After ◽  
Post Synthesis

AbstractNanoparticles may be used in vaccinology as an antigen delivery and/or an immunostimulant to enhance immunity. Porous silica has been identified as an effective adjuvant for more than a decade, and we have therefore investigated the take up rate by an immortalized macrophage-like cell line of a number of mesoporous silica nanoparticles (MSNPs) with differing diameter and pore size. The MSNPs were synthesized using a sol-gel reaction and post-synthesis removal of the template. The MSNPs showed a clear distribution in take up rate peaking at 217 nm, whereas a comparison with solid spherical nanoparticles showed a similar distribution peaking at 377 nm. The MSNPs were investigated before and after loading with antigen. Diphtheria toxoid was used as a proof-of-concept antigen and showed a peak macrophage internalization of 53.42% for loaded LP3 particles which had a diameter of 217.75 ± 5.44 nm and large 16.5 nm pores. Optimal MSNP sizes appeared to be in the 200–400 nm range, and larger pores showed better antigen loading. The mesoporous silica particles were shown to be generally biocompatible, and cell viability was not altered by the loading of particles with or without antigen.

scholarly journals The effect of pore morphology on the catalytic performance of β-glucosidase immobilized into mesoporous silica

2019 ◽  
Vol 91 (10) ◽  
pp. 1583-1592 ◽  
Author(s):  
Valeria Califano ◽  
Aniello Costantini ◽  
Brigida Silvestri ◽  
Virginia Venezia ◽  
Stefano Cimino ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Catalytic Performance ◽  
Morphological Characterization ◽  
Transmission Electron ◽  
Cellobiose Hydrolysis ◽  
Two Samples ◽  
Bet Method ◽  
Key Factor

Abstract β-Glucosidase (BG) was immobilized by adsorption on wrinkled silica nanoparticles (WSNs) and on tannic acid-templated mesoporous silica nanoparticles (TA-MSNPs). The effect induced by a different morphology of the pores of the sorbent on the catalytic performance of β-glucosidase was investigated. A complete textural and morphological characterization of the two samples was performed by Brunauer–Emmett–Teller (BET) method, Fourier Transform Infrared (FT-IR) and transmission electron microscopy (TEM). The results demonstrated that the catalytic performance of the immobilized enzyme depends on the pores size of sorbent but a key factor is the pores morphology. In fact, the BG immobilized on WSNs and TA-MSNPs (BG/WSNs and BG/TA-MSNPs) shows in both cases good catalytic performances in cellobiose hydrolysis, but the catalyst with the best performance is BG/WSNs, in which the support exhibits a central-radial pore structure and a hierarchical trimodal micro-mesoporous pore size. This peculiar morphology allows the enzyme to settle in a place where the interactions with the walls are maximized, increasing its conformational rigidity. Furthermore, the enzyme is prevalently collocated in the interior of pore so that the pores are not completely capped.

scholarly journals Recent Trends in Morphology-Controlled Synthesis and Application of Mesoporous Silica Nanoparticles

Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2122
Author(s):  
Nabanita Pal ◽  
Jun-Hyeok Lee ◽  
Eun-Bum Cho
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
High Surface Area ◽  
Porous Silica ◽  
The United States ◽  
Structural Features ◽  
Energy Applications ◽  
Silica Materials

The outstanding journey towards the investigation of mesoporous materials commences with the discovery of high surface area porous silica materials, named MCM-41 (Mobil Composition of Matter-41) according to the inventors’ name Mobile scientists in the United States. Based on a self-assembled supramolecular templating mechanism, the synthesis of mesoporous silica has extended to wide varieties of silica categories along with versatile applications of all these types in many fields. These silica families have some extraordinary structural features, like highly tunable nanoscale sized pore diameter, good Brunauer–Emmett–Teller (BET) surface areas, good flexibility to accommodate different organic and inorganic functional groups, metals etc., onto their surface. As a consequence, thousands of scientists and researchers throughout the world have reported numerous silica materials in the form of published articles, communication, reviews, etc. Beside this, attention is also given to the morphology-oriented synthesis of silica nanoparticles and their significant effects on the emerging fields of study like catalysis, energy applications, sensing, environmental, and biomedical research. This review highlights a consolidated overview of those morphology-based mesoporous silica particles, emphasizing their syntheses and potential role in many promising fields of research.

Hybrid biomaterial based on porous silica nanoparticles and Pluronic F-127 for sustained release of sildenafil: in vivo study on prostate cancer

RSC Advances ◽  
2015 ◽  
Vol 5 (99) ◽  
pp. 81348-81355 ◽  
Author(s):  
C. P. Silveira ◽  
L. M. Apolinário ◽  
W. J. Fávaro ◽  
A. J. Paula ◽  
N. Durán
Keyword(s):  
Prostate Cancer ◽  
Mesoporous Silica ◽  
Sustained Release ◽  
Silica Nanoparticles ◽  
High Efficiency ◽  
Mesoporous Silica Nanoparticles ◽  
Porous Silica ◽  
In Vivo Study ◽  
Hydrogel System

We describe here a drug depot hydrogel system comprising sildenafil (Viagra®) incorporated in mesoporous silica nanoparticles (60 nm) and conjugated with a thermosensitive poloxamer, which presents a high efficiency against prostate cancer.

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