Olfactory analogue to directional hearing

1964 ◽  
Vol 19 (3) ◽  
pp. 369-373 ◽  
Author(s):  
Georg von Békésy

The direction of a sound source can be determined binaurally by using the time difference and the loudness difference of the sound waves arriving at the two ears. Similarly, the direction of an olfactory source can be determined by using the time difference and the difference in sensation magnitude of the olfactory stimuli between the two nostrils as the air surrounding the odorous object is inhaled. Time differences of the order of 0.1 msec can be recognized—a value similar to that found in hearing. Thus the direction of an odor can be determined with a precision of 7–10° in spite of the small distance between the nostrils compared to the distance between the ears. In this respect, there is very little difference between observations made with such odorants as benzol, eucalyptus, cloves, and lavender. The existence of an analogy between hearing and smelling may help to delineate some electrophysiological correlates of the directional sensation, which is so well developed in both senses. localization of olfactory stimuli; interaction between the two nostrils during smelling; time pattern and olfactory localization; olfactory sensation magnitude and duration of stimulus; combination of smell and taste into a single sensation Submitted on November 1, 1963

2020 ◽  
Vol 7 (2) ◽  
pp. 107-112
Author(s):  
Marian Manciu ◽  
Sorour Hosseini ◽  
Joscelyne Guzman-Gonzalez

Background: Statistical methods commonly used in survival analysis typically provide the probability that the difference between groups is due to chance, but do not offer a reliable estimate of the average survival time difference between groups (the difference between median survival time is usually reported). Objective: We suggest a Maximum-Entropy estimator for the average Survival Time Difference (MESTD) between groups. Methods: The estimator is based on the extra survival time, which should be added to each member of the group, to produce the maximum entropy of the result (resulting in the groups becoming most similar). The estimator is calculated only from time to event data, does not necessarily assume hazard proportionality and provides the magnitude of the clinical differences between the groups. Results: Monte Carlo simulations show that, even at low sample numbers (much lower than the ones needed to prove that the two groups are statistically different), the MESTD estimator is a reliable predictor of the clinical differences between the groups, and therefore can be used to estimate from (low sample numbers) preliminary data whether or not the large sample number experiment is worth pursuing. Conclusion: By providing a reasonable estimate for the efficacy of a treatment (e.g., for cancer) even for low sample data, it might provide useful insight in testing new methods for treatment (for example, for quick testing of multiple combinations of cancer drugs).


2021 ◽  
Vol 13 (12) ◽  
pp. 6914
Author(s):  
Frikkie Alberts Maré ◽  
Henry Jordaan

The high water intake and wastewater discharge of slaughterhouses have been a concern for many years. One neglected factor in previous research is allocating the water footprint (WF) to beef production’s different products and by-products. The objective of this article was to estimate the WF of different cattle breeds at a slaughterhouse and cutting plant and allocate it according to the different cuts (products) and by-products of beef based on the value fraction of each. The results indicated a negative relationship between the carcass weight and the processing WF when the different breeds were compared. Regarding a specific cut of beef, a kilogram of rib eye from the heaviest breed had a processing WF of 614.57 L/kg, compared to the 919.91 L/kg for the rib eye of the lightest breed. A comparison of the different cuts indicated that high-value cuts had higher WFs than low-value cuts. The difference between a kilogram of rib eye and flank was 426.26 L/kg for the heaviest breed and 637.86 L/kg for the lightest breed. An option to reduce the processing WF of beef is to lessen the WF by slaughtering heavier animals. This will require no extra investment from the slaughterhouse. At the same time, the returns should increase as the average production inputs per kilogram of output (carcass) should reduce, as the slaughterhouse will process more kilograms.


1966 ◽  
Vol 21 (9) ◽  
pp. 1377-1384
Author(s):  
A. V. Willi

Kinetic carbon-13 and deuterium isotope effects are calculated for the SN2 reaction of CH3I with CN-. The normal vibrational frequencies of CH3I, the transition state I · · · CH3 · · · CN, and the corresponding isotope substituted reactants and transition states are evaluated from the force constants by solving the secular equation on an IBM 7094 computer.Values for 7 force constants of the planar CH3 moiety in the transition state (with an sp2 C atom) are obtained by comparison with suitable stable molecules. The stretching force constants related to the bonds being broken or newly formed (fCC, fCC and the interaction between these two stretches, /12) are chosen in such a way that either a zero or imaginary value for νʟ≠ will result. Agreement between calculated and experimental methyl-C13 isotope effects (k12/ k13) can be obtained only in sample calculations with sufficiently large values of f12 which lead to imaginary νʟ≠ values. Furthermore, the difference between fCI and fCC must be small (in the order of 1 mdyn/Å). The bending force constants, fHCI and fHCC, exert relatively little influence on k12/k13. They are important for the D isotope effect, however. As soon as experimental data on kH/kD are available it will be possible to derive a value for fHCC in the transition state if fHCI is kept constant at 0.205 mdynA, and if fCI, fCC and f12 are held in a reasonable order of magnitude. There is no agreement between experimental and calculated cyanide-C13 isotope effects. Possible explanations are discussed. — Since fCI and fCC cannot differ much it must be concluded that the transition state is relatively “symmetric”, with approximately equal amounts of bond making and bond breaking.


2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Farah Aida Qotrun Nada ◽  
Tintrim Rahayu ◽  
Ari Hayati

Ground coffee is coffee beans that have been roasted, ground or ground so that they have a smooth shape. The purpose of this study was to determine the content of compounds in robusta coffee roasted seed extract (Coffea canephora) from plants produced by organic and inorganic fertilization, and to know the difference in compounds between the results of organic and inorganic fertilization. The characteristics of phytochemical screening were carried out qualitatively on alkaloids, flavonoids, tannins, terpenoids and saponins and the antioxidant activity was carried out by the DPPH (1,1-dipenyl-2-picrihidrazil) method. Phytochemical screening characteristic test results show that robusta coffee bean extract extract from the results of organic and inorganic fertilization both contain flavonoids, alkaloids, tannins, and saponins, while the antioxidant test activity of robusta coffee beans extracts shows differences based on the results of statistical tests of linear regression analysis with the IC50 value the highest antioxidant content was inorganic coffee roasted bean extract only 14.0629 ppm compared to the organic roasted extract with a value of 30.6159 ppmKeywords: Robusta Coffee (Coffea canophora), Phytochemical Screening, DPPH MethodABSTRAKKopi bubuk adalah biji kopi yang telah disangrai digiling atau ditumbuk sehingga mempunyai bentuk halus. Tujuan dari penelitian ini adalah untuk mengetahui kandungan senyawa dalam ekstrak biji sangrai kopi robusta (Coffe canephora) dari tanaman hasil pemupukan organik dan anorganik, dan mengetahui perbedaan senyawa antara hasil pemupukan organik dan anorganik. Karakteristik skrining fitokimia dilakukan secara kualitatif yang dilakukan terhadap alkaloid, flavonoid, tanin, terpenoid dan saponin dan aktivitas antioksidan dilakukan dengan metode DPPH (1,1-difenil-2-pikrihidrazil). Hasil uji karakteristik skrining fitokimia menunjukkan bahwa ekstrak biji sangrai kopi robusta dari hasil pemupukan oganik dan anorganik keduanya sama mengandung senyawa flavonoid, alkaloid, tanin, dan saponin,  sedangkan pada aktifitas uji antioksidan ekstrak biji sangrai kopi robusta menunjukan perbedaan berdasarkan hasil uji statistik analisis regresi linear dengan nilai IC50 kadar antioksidan paling tinggi adalah ekstrak biji sangrai kopi anorganik hanya 14,0629 ppm dibandingkan dengan ekstrak sangrai dari organik dengan nilai 30,6159 ppm.Kata kunci : Kopi Robusta (Coffea canophera), Skrining Fitokimia, Metode DPPH


1976 ◽  
Vol 56 (3) ◽  
pp. 285-291
Author(s):  
B. TOUATI ◽  
C. PLENCHETTE ◽  
M. TABI

In a pot-type experiment with ryegrass, 32P was used to label isotopically exchangeable soil phosphorus as well as a phosphate fertilizer. The tagging of both forms of phosphorus enable us to determine the pool (L) for soil reserves and the A value which is the availability of these reserves in the presence of fertilizer. The authors establish correlations between the ratio K = L/A and the assimilable phosphorus as determined by the Bray II method, and also between K and the "extra" phosphorus. The authors state that the latter was the difference between the plant phosphorus with and without fertilizer. From this study it is concluded: (1) that the K value seems to be a better criterion than the amount of assimilable phosphorus to estimate the phosphorus fertility of a soil; (2) that the study of the variation of the K value according to the soil types informs us about the reserves behavior and about the way of nutrition for the plant. The calculation of the K value is aimed toward a more adequate fertilization for given types of soil.


Solid Earth ◽  
2016 ◽  
Vol 7 (4) ◽  
pp. 1157-1169 ◽  
Author(s):  
Paul W. J. Glover

Abstract. When scientists apply Archie's first law they often include an extra parameter a, which was introduced about 10 years after the equation's first publication by Winsauer et al. (1952), and which is sometimes called the “tortuosity” or “lithology” parameter. This parameter is not, however, theoretically justified. Paradoxically, the Winsauer et al. (1952) form of Archie's law often performs better than the original, more theoretically correct version. The difference in the cementation exponent calculated from these two forms of Archie's law is important, and can lead to a misestimation of reserves by at least 20 % for typical reservoir parameter values. We have examined the apparent paradox, and conclude that while the theoretical form of the law is correct, the data that we have been analysing with Archie's law have been in error. There are at least three types of systematic error that are present in most measurements: (i) a porosity error, (ii) a pore fluid salinity error, and (iii) a temperature error. Each of these systematic errors is sufficient to ensure that a non-unity value of the parameter a is required in order to fit the electrical data well. Fortunately, the inclusion of this parameter in the fit has compensated for the presence of the systematic errors in the electrical and porosity data, leading to a value of cementation exponent that is correct. The exceptions are those cementation exponents that have been calculated for individual core plugs. We make a number of recommendations for reducing the systematic errors that contribute to the problem and suggest that the value of the parameter a may now be used as an indication of data quality.


2019 ◽  
Vol 13 (2) ◽  
pp. 72-81
Author(s):  
Theresia Widyastuti

 Depression is a mood disorder that is generally characterized by hopelessness, excessive helplessness, and lack of enthusiasm for life. Starting from stress that is not overcome, then a person can fall into a phase of depression. This study aims to look at the effect of providing music therapy in reducing depression in the elderly before and after being given a commitment. To achieve this goal, this study uses a quasi-experimental method (Quasi Experiment). The type of research design used is Quasi Experiment with one group pretest and posttest design. The sampling technique was purposive sampling where participants based on population criteria obtained a sample of 16 people. Data collection methods using tests with a scale measuring instrument namely Geriatric Depression Scale (GDS) consisting of 30 item questions, observation methods and interview methods .. Based on data analysis it was concluded that the results obtained were Man Whitney Test U = 0.500 with a value of p = 0.001 ( p <0.01) where the mean ranks on the gain score is 12.44 and the sum of ranks is 99.50, this shows the difference in effectiveness of the effects of music therapy before and after treatment and to test the difference in levels of depression before and after being given music therapy using Wilcoxon Sign Rank test analysis . the results obtained z value = -2.539 with a value of p = 0.11 (p <0.01) so that it can be concluded that there are differences in changes in the level of depression in the elderly before and after given treatment.


2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Agista Ayu Aksari

On 1st July 2012 SOE (State-Owned Enterprises)become the Value Added Tax (VAT) collector. According to the regulation of the Ministher of Finance No.85/PMK.03/2012 about the appointment of the State Owned Enterprises to collect, deposit and reporting Value Added Tax (VAT) and Sales Tax on Luxurious Goods, and precedures for collecting, depositing and reporting. The purpose of this research is to determine the difference between SOE as a Value Added Tax collector and not as a Value Added Tax collector.The object of this research is PT Pelabuhan Indonesia III cabang Benoa. The data analysis in this research is to analyze the calculation and reportig of VAT before being VAT collector and when it became VAT collector.The result of this research it is known that are the application of the value added tax on PT Pelabuhan Indonesia III Cabang Benoa before becoming tax collector is charged directly by fiskus and has official assessment system and as a PT Pelabuhan Indonesia III Cabang Benoa has a self assessment system whereby PT Pelabuahan Indonesia III Cabang Benoa became ILL wapu. Differnce in PT Pelabuhan Indonesia III Cabang Benoa as a collector, and the collector Is a time before becoming a collector has aself just my assessment system whereas before becoming a collector has official assessment system. Tax eceipt when it became a collector of VAT using duplicate counts 3 before becoming a collector only uses 2 of the double. For SSp before becoming a duplicate while using 4 collector as a collector to use duplicate. DOI 10.5281/zenodo.1214932


Telematika ◽  
2020 ◽  
Vol 17 (1) ◽  
pp. 26
Author(s):  
Afif Irfan Abdurrahman ◽  
Bambang Yuwono ◽  
Yuli Fauziah

Flood disaster is a dangerous disaster, an event that occurs due to overflow of water resulting in submerged land is called a flood disaster. Almost every year Bantul Regency is affected by floods due to high rainfall. The flood disaster that struck in Bantul Regency made the Bantul District Disaster Management Agency (BPBD) difficult to handle so that it needed a mapping of the level of the impact of the flood disaster to minimize the occurrence of floods and provide information to the public.This study will create a system to map the level of impact of floods in Bantul Regency with a decision support method namely Multi Attribute Utility Theory (MAUT). The MAUT method stage in determining the level of impact of flood disasters through the process of normalization and matrix multiplication. The method helps in determining the areas affected by floods, by managing the Indonesian Disaster Information Data (DIBI). The data managed is data on criteria for the death toll, lost victims, damage to houses, damage to public facilities, and damage to roads. Each criteria data has a value that can be used to determine the level of impact of a flood disaster. The stages for determining the level of impact of a disaster require a weighting calculation process. The results of the weighting process display the scoring value which has a value of 1 = low, 2 = moderate, 3 = high. To assist in determining the affected areas using the matrix normalization and multiplication process the process is the application of the Multi Attribute Utility Theory (MAUT) method.This study resulted in a mapping of the level of impact displayed on google maps. The map view shows the affected area points and the level of impact of the flood disaster in Bantul Regency. The mapping produced from the DIBI data in 2017 produced the highest affected area in the Imogiri sub-district. The results of testing the data can be concluded that the results of this study have an accuracy rate of 95% when compared with the results of the mapping previously carried out by BPBD Bantul Regency. The difference in the level of accuracy is because the criteria data used are not the same as the criteria data used by BPBD in Bantul Regency so that the accuracy rate is 95%.


2021 ◽  
Vol 9 (3) ◽  
pp. 305
Author(s):  
Muhammad Lutfi ◽  
Zainuddin Zainuddin ◽  
Eko Susilowati

Preliminary observations show the limitations of teaching materials that have a relationship with spiritual aspects, especially the Qur'an, which is due to the limitations of teaching materials that contain these aspects. Required learning that stimulates students to generalize religious aspects and learn physics. Therefore, the purpose of this study is to describe the feasibility of physics teaching materials containing the Qur'an by using a generative model on sound wave material. This study aims to describe the validity, practicality, and effectiveness of the teaching materials developed. The research was conducted on 33 students at class XI MIPA 1 MAN 2 Model Banjarmasin using the ADDIE model. Data was taken from the validation results of teaching materials using validation sheet, lesson plan implementation using lesson plan implementation sheet, and students' learning outcomes at the pretest and post-test using learning outcomes tests. The results of this study were 1) the validity of the teaching materials was in the "valid" category with a value of 3.33, 2) the practicality of the teaching materials was in the "very practical" category with a value of 3.63, and 3) the effectiveness of the teaching material was in the "effective/moderate" category with a value of 0,44. This study concluded that physics teaching materials containing Al-Qur'an verses on sound wave materials using generative learning models are declared feasible to be used based on the validity, practicality, and effectiveness of the teaching materials. The implication of this research is the creation of teaching materials containing the Qur'an that are used in schools and creating student habits to link physics and the Qur'an.


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