Effects of erythrocyte infusion on VO2max at high altitude

1996 ◽  
Vol 81 (1) ◽  
pp. 252-259 ◽  
Author(s):  
A. J. Young ◽  
M. N. Sawka ◽  
S. R. Muza ◽  
R. Boushel ◽  
T. Lyons ◽  
...  
Keyword(s):  
High Altitude ◽  
Sea Level ◽  
Carrying Capacity ◽  
Hemoglobin Concentration ◽  
Treadmill Running ◽  
Control Group ◽  
O2 Uptake ◽  
Control Subjects ◽  
And Control ◽  
Experimental Group

This study investigated whether autologous erythrocyte infusion would ameliorate the decrement in maximal O2 uptake (VO2max) experienced by lowlanders when they ascend to high altitude. VO2max was measured in 16 men (treadmill running) at sea level (SL) and on the 1st (HA1) and 9th (HA9) days of high-altitude (4,300 m) residence. After VO2max was measured at SL, subjects were divided into two matched groups (n = 8). Twenty-four hours before ascent to high altitude, the experimental group received a 700-ml infusion of autologous erythrocytes and saline (42% hematocrit), whereas the control group received only saline. The VO2max of erythrocyte-infused [54 +/- 1 (SE) ml.kg-1.min-1] and control subjects (52 +/- 2 ml.kg-1.min-1) did not differ at SL before infusion. The decrement in VO2max on HA1 did not differ between groups, averaging 26% overall, despite higher (P < 0.01) arterial hematocrit, hemoglobin concentration, and arterial O2 content in the erythrocyte-infused subjects. By HA9, there were no longer any differences in hematocrit, hemoglobin concentration, or arterial O2 content between groups. No change in VO2max occurred between HA1 and HA9 for either group. Thus, despite increasing arterial O2-carrying capacity, autologous erythrocyte infusion did not ameliorate the decrement in VO2max at 4,300-m altitude.

scholarly journals Responses of developmental and physiological traits to manipulated incubation conditions in broiler embryos at hypoxic high altitude

2018 ◽  
Vol 61 (3) ◽  
pp. 337-349 ◽  
Author(s):  
Elif Babacanoğlu
Keyword(s):  
High Altitude ◽  
Sea Level ◽  
Water Loss ◽  
Incubation Temperature ◽  
Hemoglobin Concentration ◽  
Physiological Traits ◽  
Control Group ◽  
Broiler Breeders ◽  
Incubation Condition ◽  
Hatching Eggs

Abstract. The effects of hypoxia at increased altitude levels on the cardio-respiratory development of broiler embryos are distinct in comparison with those at sea level. The aim of the study was to investigate the effects of high incubation temperature (H) and oxygen supplementation (O) during hypoxic high altitude (HA) on developmental and physiological traits of embryos and hatching performance of embryonated hatching eggs in broilers at different embryonic stages. A total of 1280 eggs obtained from broiler breeders laid at sea level were used. Eggshell quality characteristics were measured for 20 eggs. The rest of the 1260 eggs were divided into seven incubation condition (IC) groups (180 eggs per group) including a control group at 37.8 ∘C and 21 % O2; O groups, with daily 1 h 23.5 % O2 supplementation at 37.8 ∘C as O0−11, O12−21, and O18−21; H groups at 38.5 ∘C high incubation temperature at 21 % O2 as H0−11, H12−21, and H18−21 from days 0 to 11, 12 to 21, and 18 to 21 of incubation, respectively. All groups were incubated in three different incubators at hypoxic HA. The effect of IC was determined on eggshell temperature, hatching performance, embryo development, right ventricular (RV) to total ventricular (TV) ratio, and blood parameters. The highest egg water loss and embryonic mortality and the lowest hatchability were in the H0−11 group, which depended on increased eggshell temperature during incubation. On day 18 of incubation, due to the decreased egg water loss in the O12−21 and O18−21 groups, there was an increase in hatchability in fertile eggs similar to the middle and late H groups. Towards the end of incubation, embryo/chick weights were not different and RV and TV weights increased in the treated groups, and the RV ∕ TV ratio changed between 15 and 26 %. At hatching, yolk sac weight increased in H0−11 and H12−21 groups. The O groups had the lowest serum tri-iodothyronine (T3) concentration as distinct from H groups. The serum thyroxine (T4) concentration increased in the treated groups, dependent on sex of the embryo. Blood hemoglobin concentration of O groups decreased relative to other groups. The hematocrit value was the lowest in the O12−21 and highest in the H12−21 groups. The H and O treatments during pre-hatch hypoxic HA condition can be positively evaluated on physiological traits of embryos after half of incubation depended on the timing of the IC exposure to the hatching eggs obtained from broiler breeders at sea level.

Functional capacities of lungs and thorax in beagles after prolonged residence at 3,100 m

1985 ◽  
Vol 59 (6) ◽  
pp. 1773-1782 ◽  
Author(s):  
R. L. Johnson ◽  
S. S. Cassidy ◽  
R. F. Grover ◽  
J. E. Schutte ◽  
R. H. Epstein
Keyword(s):  
High Altitude ◽  
Sea Level ◽  
Pulmonary Blood Flow ◽  
Lung Volumes ◽  
Anatomical Distribution ◽  
X Ray ◽  
Control Subjects ◽  
X Ray Computed ◽  
Functional Capacities ◽  
And Control

Functional capacities of the lungs and thorax in beagles taken to high altitude as adults for 33 mo or in beagles raised from puppies at high altitude were compared with functional capacities in corresponding sets of beagles kept simultaneously at sea level. Comparisons were made after reacclimatization to sea level. Lung volumes, airway pressures, esophageal pressures, CO diffusing capacities (DLCO), pulmonary blood flow, and lung tissue volume (Vt) were measured by a rebreathing technique at inspired volumes ranging from 15 to 90 ml/kg. In beagles raised from puppies we measured anatomical distribution of intrathoracic air and tissue using X-ray computed tomography at transpulmonary pressures of 20 cm H2O. Lung and thoracic distensibility, DLCO, and Vt were not different between beagles that had been kept at high altitude for 33 mo as adults and control subjects kept simultaneously at sea level. Lung distensibility, DLCO, and Vt were significantly greater in beagles raised at high altitude than control subjects raised simultaneously at sea level. Thoracic distensibility was not increased in beagles raised at high altitude; the larger lung volume was accommodated by a lower diaphragm, not a larger rib cage.

scholarly journals THE EFFECT OF INTENSIVE DOGS INVASION BY DIROFILARIASIS ON THE MORPHOLOGICAL PICTURE OF BLOOD

2019 ◽  
pp. 238-241 ◽  
Author(s):  
Kabardiev ◽  
Bittirova ◽  
Bittirov ◽  
Kabardiev ◽  
Begieva ◽  
...  
Keyword(s):  
High Intensity ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Blood Samples ◽  
Hematological Profile ◽  
Morphological Picture ◽  
Morphological Composition ◽  
And Control ◽  
Experimental Group ◽  
Forearm Vein

New data were obtained when studying the effect of intensive dirofilariоsis invasion on the morphological composition of the blood corpus of infected dogs. Hematological studies were performed on 20 dogs infected intensively with microfilaria. Blood from dogs was taken from a forearm vein in test tubes with an anticoagulant. For research, 2 groups were formed: experimental and control. The experimental group (n=10) consisted of dogs that had microfilaria dirofilariasis in blood samples. The control group of dogs (n=10) was formed from agelminthous animals, in the blood of which there were no nematode microfilaria. Results. With intensive invasion of dirofilariоsis in blood samples of dogs, a decrease in the number of erythrocytes is observed by 3.03х1012/l, a decrease in hemoglobin concentration by 70.68 g/l. At the same time, the number of leukocytes in the hematological profile of experienced dogs increased by 14.68х109/l, and that of eosinophils by 497.44%, which indicates profound pathophysiological changes in the hematocrit. Conclusion With a high intensity of dirofilariasis in dogs, erythropenia, hypohemoglobinemia, leukocytosis, and eosinophilia appear strongly on the background of control.

The Effect of Applying POSSE (Predict- Organize-Search-Summarize-Evaluate) on the Students’ Reading Comprehension

2013 ◽  
Vol 2 (1) ◽  
Author(s):  
Eka Rejeki Maha ◽  
Berlin Sibarani
Keyword(s):  
Reading Comprehension ◽  
Experimental Design ◽  
Null Hypothesis ◽  
Alternative Hypothesis ◽  
Choice Test ◽  
Control Group ◽  
Multiple Choice Test ◽  
Level Of Significance ◽  
And Control ◽  
Experimental Group

This study was aimed at finding out The Effect of Applying POSSE (Predict-Organize-Search-Summarize-Evaluate) Strategy on the Students’ Reading Comprehension. This study used the experimental design. The population of this study was the students of SMA Negeri 2 Medan. There were sixty students taken as the sample of the research. This study was conducted with two randomized groups namely experimental and control group. The experimental group was taught by applying POSSE strategy while control group was taught without applying POSSE strategy. The instrument of collecting the data was multiple choice test which consists of 40 items. To obtain the reliability of the test, the researcher used Kuder-Richardson (KR-21). The calculation shows the reliability was 0.81(high). The data were analyzed by using t-test. The calculation shows that t-observed (4.76) is higher than t-table (2.00) at the level of significance (α) 0.05 with the degree of freedom (df) 58. Therefore, the null hypothesis (Ho) is rejected and alternative hypothesis (Ha) is accepted. It means that there was a significant effect of applying POSSE strategy on the students’ reading comprehension. Keywords: POSSE Strategy, Reading Comprehension.

The Effect of Applying Learning Together Method on the Students’ Reading Comprehension

2012 ◽  
Vol 1 (2) ◽  
Author(s):  
Haryato Siregar ◽  
Elia Masa Ginting
Keyword(s):  
Reading Comprehension ◽  
Alternative Hypothesis ◽  
Choice Test ◽  
Control Group ◽  
Teaching Reading ◽  
Multiple Choice Test ◽  
Level Of Significance ◽  
And Control ◽  
Experimental Group ◽  
Learning Together

This study was aimed at finding out the effect of applying Learning Together Method on the students’ reading comprehension. This study used the experimental design. The population of this study was the students of SMP Negeri 1 Muara. There were sixty students of eighth class as the sample of the research. This study was conducted with two randomized groups namely experimental and control group. The experimental group was taught by applying Learning Together Method while control group was taught without applying Learning Together Method. The instrument of collecting the data was multiple choice test which consists of 20 items. To obtain the reliability of the test, the researcher used Kuder-Richardson (KR-21) formula. The calculation shows the reliability was 0.82(high). The data were analyzed by using t-test. The calculation shows that t-observed (4.9) is higher than t-table (2.00) at the level of significance (α) 0.05 with the degree of freedom (df) 58. Therefore, the null hypothesis (Ho) is rejected and alternative hypothesis (Ha) is accepted. It means that teaching reading comprehension by applying Learning Together Method significantly affect reading comprehension. Keywords: Learning Together Method, Reading Comprehension

THE EFFECT OF APPLYING ANIMAL CARTOON PICTURES ON STUDENTS’ ACHIEVEMENT IN WRITING NARRATIVE TEXT

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Hasanul Arifin Zul And Masitowarni Siregar
Keyword(s):  
T Test ◽  
Narrative Text ◽  
Control Group ◽  
First Year ◽  
Writing Achievement ◽  
Control Groups ◽  
Post Test ◽  
Written Test ◽  
And Control ◽  
Experimental Group

This thesis is focused on the investigation of the effect of applying animal cartoon pictures on students’ achievement in writing narrative text. This study aims to find whether applying animal cartoon pictures significantly affect the students’ writing achievement or not. The data in this study were obtained by administering a written test. The population was the 2015/2016 first year (grade XI) of SMA Swasta Nusantara Lubuk Pakam and 66 students were taken as the sample by using random sampling. The sample was divided into two groups, experimental and control groups. The experimental group was taught by applying animal cartoon pictures while the control group without animal cartoon pictures (x = lecturing). The data were taken the scores from the pre-test and post-test to both experimental and control groups. These data were analyzed by using t-test. The result of computing the t-test obviously showed that t-observed is higher than t-table (5.21 >1,67) with the degree of freedom 64 (df =N-2) at the level significance 0,05 one tail test. It showed that the application of animal cartoon pictures significantly affected the students of SMA Swasta Nusantara Lubuk Pakam achievement in writing narrative text.

THE EFFECT OF PEER REVIEW STRATEGY ON THE STUDENTS’ ACHIEVEMENT IN WRITING DESCRIPTIVE PARAGRAPH

2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Sri Agus Murniasih And I Wayan Dirgeyasa
Keyword(s):  
Peer Review ◽  
Experimental Research ◽  
Research Method ◽  
Alternative Hypothesis ◽  
Control Group ◽  
Post Test ◽  
Class Viii ◽  
And Control ◽  
Essay Test ◽  
Experimental Group

This study was conducted to know the effect of applying Peer Review Strategy on the students’ achievement in writing descriptive paragraph. It was conducted by using experimental research method. This research design was conducted pre-test, post test in experimental and control group. The population of this research was the eight (VIII) grade students of SMP IT IQRA’ Medan. The sample of this research was taken by lottery technique. They were in class VIII-1 by experimental group and the class VIII-2 by control group. The experimental group was taught by using Peer Review Strategy while the control group was given no treatment. The instrument used to collect the data was writing essay test. The data were analyzed by using t-test formula. The result showed that the value of t-observed was higher than the value of t-table. (3,55 > 2,05 (a = 0.05)) with the degree of freedom (df) = 28. It means that there was a significant effect of applying Peer Review Strategy on the students’ achievement in writing descriptive paragraph. So, the alternative hypothesis (Ha) was accepted.

THE EFFECT OF APPLYING DEMONSTRATION METHOD ON STUDENTS’ ACHIEVEMENT IN SPEAKING SKILL AT THE THIRD GRADE OF SMK PAB 3 MEDAN ESTATE

2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Meryanti Napitupulu And Anni Holila Pulungan
Keyword(s):  
High School ◽  
Control Group ◽  
Vocational High School ◽  
Control Groups ◽  
Speaking Test ◽  
The Third ◽  
Speaking Skill ◽  
The Subject ◽  
And Control ◽  
Experimental Group

This study was conducted as an attempt to discover the effect of applying Demonstration Method on students’ achievement in speaking skill. It was an experimental research. The subject was students of Grade XII, Vocational High School (Sekolah Menengah Kejuruan: SMK), which consisted of 79 students. The research was divided into two groups: experimental and control groups. The instrument used to collect the data was speaking test. To obtain the reliability of the test, the writer applied Kuder Richardson 21 formula. The result of the reliability was 0.7, and it was found that the test was reliable. The data were analyzed by using t-test formula. The analysis showed that the scores of the students in the experimental group were significantly higher than the scores of the students in the control group at the level of significant m = 0.05 with the degree of freedom (df) 77, t-observed value 8.9 > t-table value 1.99. The findings indicate that using Demonstration Method significantly affected the students’ achievement in speaking skill. So, English teachers are suggested to use Demonstration Method in order to improve students’ achievement in speaking skill.

THE EFFECT OF RAP (READ, ASK, PARAPHRASE) STRATEGY ON STUDENTS’ READING COMPREHENSION IN READING ANALYTICAL EXPOSITION TEXT

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Veronika N. And Lince Sihombing
Keyword(s):  
Reading Comprehension ◽  
Experimental Design ◽  
T Test ◽  
Control Group ◽  
Multiple Choice Tests ◽  
Choice Tests ◽  
Second Year ◽  
Level Of Significance ◽  
And Control ◽  
Experimental Group

This study focused on finding out the effect of applying RAP (Read, Ask,Paraphrase) Strategy on students’ reading comprehension in reading analyticalexposition text. This study was conducted in experimental design. The populationof this research was the second year of students in SMA Swasta Katolik BudiMurni 2 Medan. There were seventy students of the second year senior highschool students as the sample of the research. This study was conducted with tworandomized groups namely Experimental Group and Control Group. Theexperimental group was taught by applying RAP Strategy, while the control groupwas taught by applying conventional strategy. The instrument of collecting thedata was multiple choice tests which consisted of 25 items. The data wereanalyzed by using t-test formula. The calculation shown that t-observed (5.36)was higher than t-table (1.994) at the level of significance (α) 0.05 with the degreeof freedom (df) 68. It means that there was a significant effect of applying RAPStrategy on students’ reading comprehension in reading analytical exposition text.

THE EFFECT OF APPLYING SQ3R METHOD ON STUDENTS’ ACHIEVEMENT IN READING COMPREHENSION

2013 ◽  
Vol 2 (2) ◽  
Author(s):  
Pranata Royganda Sihaloho And Masitowarni Siregar
Keyword(s):  
Reading Comprehension ◽  
Research Design ◽  
Conventional Method ◽  
Experimental Research ◽  
T Test ◽  
Control Group ◽  
Multiple Choice Tests ◽  
Choice Tests ◽  
And Control ◽  
Experimental Group

The aim of this study is to discover the effect of applying SQ3R method inreading comprehension. Experimental research design is used as the research method.This research took place at SMA Nasrani 2Medan. There were 2 classes chosen as thesample with 30 students in each class. The classes were divided into two groups namelyexperimental and control group. The experimental group was taught by using SQ3Rmethod and the control group was taught by using conventional method. The instrumentused to collect the data was a set of multiple choice tests, which divided as pre test andpost test. The result of the research was analyzed by using t-test formula. The resultshowed that t-test was higher than t-table (4,23>2,00) at the level of significant 0,05with degree of freedom (df) 58. It means that hypothesis alternative (Ha) is acceptedwhich shows that SQ3R method significantly improves the student’s readingcomprehension.

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