scholarly journals The Lyon Clinical Olfactory Test: Validation and Measurement of Hyposmia and Anosmia in Healthy and Diseased Populations

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Catherine Rouby ◽  
Thierry Thomas-Danguin ◽  
Michel Vigouroux ◽  
Gabriela Ciuperca ◽  
Tao Jiang ◽  
...  
Keyword(s):  
Validation Study ◽  
The Elderly ◽  
Test Validation ◽  
Control Group ◽  
Healthy Population ◽  
Olfactory Test ◽  
Cutoff Values ◽  
Detection And Identification ◽  
Elderly Control

The LCOT is a self-administered test designed to assess olfactory deficits. Altogether, 525 subjects contributed to the validation. Elderly participants were well represented in this sample. In a validation study (study 1), 407 healthy and 17 anosmic volunteers between 15 and 91 years of age underwent threshold, supraliminal detection, and identification testing. Cutoff values for normosmia and hyposmia were calculated and applied in a second study in a group of patients with smell complaints and in a group of Alzheimer patients with age-matched controls. Incidence of smell deficit was estimated at 5.6% in the healthy population of study 1, and at 16% in the elderly control group of study 2. Assessment of the ability of each subtest to discriminate between groups showed that LCOT is relevant to differentiating between perception and identification deficits and between Alzheimer's and hyposmic patients.

scholarly journals Bone Marrow Mesenchymal Stem Cells Derived From Juvenile Macaques Reversed Ovarian Aging in Elderly Macaques

2021 ◽  
Author(s):  
Chuan Tian ◽  
Jie He ◽  
Yuanyuan An ◽  
Zailing Yang ◽  
Donghai Yan ◽  
...  
Keyword(s):  
Stem Cell ◽  
Treatment Group ◽  
Hormone Secretion ◽  
The Elderly ◽  
Sex Hormone ◽  
Control Group ◽  
Young Control ◽  
Ovarian Aging ◽  
Elderly Control ◽  
Ovarian Senescence

Abstract Background Female sex hormone secretion and reproductive ability decrease with ageing. Bone marrow mesenchymal stem cells (BMMSCs) have been postulated to play a key role in treating ovarian senescence; however, the curative effect and mechanism are not clear. Methods We used the macaque ovarian senescence model and observed the structural and functional effects of juvenile BMMSCs in the treatment of ageing macaque ovaries. Moreover, to elucidate the molecular regulatory mechanism by which BMMSCs reverse ovarian senescence, RNA sequencing (RNA-seq) of the ovaries was used to identify key genes and signalling pathways associated with transcriptome profile changes. Results (1) The Rhesus monkey ovarian aging models were an average of 24 years old and had the following sex hormone levels: 0.28 ± 0.11 mIU/mL hFSH, 0.017 ± 0.009 mIU/mL hLH, 0.24 ± 0.042 ng/mL Testo, 51.86 ± 18.37 pg/mL ESTRDL, 0.13 ± 0.012 ng/mL Prog, 0.013 ± 0.012 hCG, and 11.96 ± 2.96 pmol/l AMH. The ovarian organ index was 0.057 ± 0.021, and the HE staining results showed almost no follicular structure, with only local atresia follicles observed. For young rhesus monkeys, the average age was 7 years old, and sex hormone levels were as follows: 0.043 ± 0.03 mIU/mL hFSH, 0.007 ± 0.009 mIU/mL hLH, 0.57 ± 0.15 ng/mL Testo, 123.2 ± 26.26 pg/mL ESTRDL, 0.28 ± 0.014 ng/mL Prog, 0.05 ± 0.012 hCG and 11.96 ± 2.96 pmol/l AMH. The ovarian organ index was 0.011 ± 0.005, and the HE staining results showed all levels of follicles, suggesting that senile ovaries occur in old macaques. (2) P4 generation BMMSCs presented a typical cell morphology, staining positive for Oil Red O, Alizarin Red, and Alcian Blue. The positive rates of CD29, CD34, CD90, and CD105 on the cell surface were 98, 0.98, 98.8, and 99.8%, respectively, in line with mesenchymal stem cell standards. (3) The PET-CT results showed that the ovarian volume in the elderly treatment group increased, the lesions decreased, and the metabolism was vigorous. (4) The level of sex hormone secretion generally recovered to the level of the follicular phase for the 3rd, 6th and 8th months after the treatment of BMMSCs. (5) The HE results showed that all levels of follicles were observed in the young control group, and the medulla and stroma were neatly arranged, whereas primitive, primary, secondary, and atretic follicles were observed in the elderly treatment group. In addition, the medulla and stroma had obvious boundaries with a small amount of calcium nodules in the young control group. while those in the elderly control group had essentially no follicular structure, with only atretic follicles were seen locally that were filled with connective tissue. Masson staining results showed that the proportion of collagen fibres was 10.61 ± 1.83% in the young control group, 56.79 ± 3.58% in the elderly control group, and 23.71 ± 2.4% in the elderly treatment group. TUNEL staining results showed that cell apoptosis was 1.07 ± 0.04%, in the young control group was, 25.93 + 2.49% in the old control group, and 6.98 + 1.35% in the old treatment group. The immunohistochemistry results showed 114 ± 17, 73 ± 6, and 118 ± 18 blood vessels in the young control group, the elderly control group, and the elderly treatment group, respectively. Immunofluorescence staining showed a lack of expression of enhanced green fluorescence protein (E-GFP) in BMMSCs without from the old control group, while green fluorescence was observed in the old treatment group. (6) After the treatment of BMMSCs, 1258 genes were identified as being differentially expressed. The 3D-PCA trace showed that the ovaries of the macaques in the elderly treatment group shifted to that observed in the young group. The genes that were upregulated with age were downregulated after the stem cell treatment. Genes that are downregulated with age were upregulated after stem cell therapy, and the top 20 PPI network genes were enriched for the progesterone-mediated maturation of follicles, oocytes, and cell cycle categories. Conclusions BMMSCs derived from juvenile macaques can reverse ovarian aging in elderly macaques

PENGARUH TERAPI TERTAWA TERHADAP PENURUNAN TEKANAN DARAH LANSIA DI UPT PANTI WREDHA BUDHI DHARMA YOGYAKARTA

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Niken Setyaningrum ◽  
Andri Setyorini ◽  
Fachruddin Tri Fitrianta
Keyword(s):  
Blood Pressure ◽  
Data Analysis ◽  
The Elderly ◽  
Control Group ◽  
Group Comparison ◽  
Control Blood Pressure ◽  
Men And Women ◽  
Treatment Of Hypertension ◽  
Before And After ◽  
The Difference

ABSTRACTBackground: Hypertension is one of the most common diseases, because this disease is suffered byboth men and women, as well as adults and young people. Treatment of hypertension does not onlyrely on medications from the doctor or regulate diet alone, but it is also important to make our bodyalways relaxed. Laughter can help to control blood pressure by reducing endocrine stress andcreating a relaxed condition to deal with relaxation.Objective: The general objective of the study was to determine the effect of laughter therapy ondecreasing elderly blood pressure in UPT Panti Wredha Budhi Dharma Yogyakarta.Methods: The design used in this study is a pre-experimental design study with one group pre-posttestresearch design where there is no control group (comparison). The population in this study wereelderly aged over> 60 years at 55 UPT Panti Wredha Budhi Dharma Yogyakarta. The method oftaking in this study uses total sampling. The sample in this study were 55 elderly. Data analysis wasused to determine the difference in blood pressure before and after laughing therapy with a ratio datascale that was using Pairs T-TestResult: There is an effect of laughing therapy on blood pressure in the elderly at UPT Panti WredhaBudhi Dharma Yogyakarta marked with a significant value of 0.000 (P <0.05)

The effect of brain vitalization activity on dementia incidence in elderly at Budi Luhur Nursing Home of Yogyakarta, Kasongan, Bantul

2020 ◽  
Vol 1 (3) ◽  
pp. 43-50
Author(s):  
Firstyono Miftahul Aziz ◽  
Suratini Suratini
Keyword(s):  
Nursing Home ◽  
The Elderly ◽  
Control Group ◽  
P Value ◽  
Sampling System ◽  
Randomized Sampling ◽  
Care For The Elderly ◽  
Dementia Incidence ◽  
The Family ◽  
The Impact

For some people, dementia is considered as a disease that is common in elderly, regardless the impact of dementia. Taking care for the elderly with dementia brings stress for the family. It can cause and increase the family burden. Brain vitalization gymnastics is one of the methods to improve memory. The study aims to investigate the effect of brain vitalization activity on dementia incidence in elderly at Budi Luhur Nursing Home of Yogyakarta. The study used Quasi Experimental with Pretest-Posttest control group and randomized sampling system. The samples were taken randomly as many as 26 respondents and were divided into two groups namely 13 respondents of experimental group and 13 respondents of control group. The statistical test used Wilcoxon Match Pairs Test. The result showed that Wilcoxon Match pairs test obtained p value 0,003, which is smaller than 0,005. There is an effect of brain vitalization activity on dementia incidence in elderly at Budi Luhur Nursing Home of Yogyakarta

Population Study on the Impact Food Chemical Composition on Patients with Non-Alcoholic Fatty Liver Diseases

2018 ◽  
Vol 69 (4) ◽  
pp. 961-964
Author(s):  
Andrei Vasile Olteanu ◽  
Georgiana Emmanuela Gilca Blanariu ◽  
Gheorghe Gh. Balan ◽  
Dana Elena Mitrica ◽  
Elena Gologan ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Fatty Liver ◽  
Nutritional Value ◽  
Liver Steatosis ◽  
Saturated Fat ◽  
Control Group ◽  
Healthy Population ◽  
Alcoholic Fatty Liver ◽  
Major Interest ◽  
The Impact

Non-alcoholic fatty liver disease (NAFLD) has become of major interest worldwide, it is estimated that more than 20% of the general population suffer from liver steatosis. NAFLD is highly associated with metabolic risk factors like type 2 diabetes mellitus, obesity and dyslipidemia, the patients diagnosed with NAFLD should adopt a high fiber low calorie diet, with reduced saturated fat and carbohydrates content, leading to weight loss and improvement of metabolic profile. Our study is aiming to shape the profile of the patient interested in being informed related to food quality and chemical composition and to evaluate the aspects on the food products label which are important for the customer. Between June 2017 and December 2017, 83 patients diagnosed with NASH were included in the study, representing the study group, while 33 subjects, without metabolic syndrome or digestive diseases, selected from patient list belonging to two general practitioners, constituted the control group. Related to the interest of being informed about the chemical composition and nutritional value of the products bought, the study showed a low interest for the provided information on nutritional value. lack of confidence in the provided information and complexity of the information are understandable, the high number of subject reasoning through lack of immediate clinical benefit is surprising. Among the healthy population the willingness to pay attention to this aspect is extremely low.

scholarly journals Role of vitamin D serum levels in prevention of primary and recurrent melanoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Lombardo ◽  
A. Vigezzi ◽  
G. Ietto ◽  
C. Franchi ◽  
V. Iori ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Levels ◽  
Mitotic Rate ◽  
Control Group ◽  
Healthy Population ◽  
Histological Subtype ◽  
Melanoma Diagnosis ◽  
Significant Difference ◽  
Tumour Location

AbstractPatients afflicted with melanoma show lower vitamin D serum levels (VDSL) than the healthy population. This hypothesis agrees with its well-known antiproliferative features. An observational study was carried out to collect VDSL in patients suffering from melanoma. Our aim was to identify a potential connection between low VDSL and the risk to incur melanoma. Furthermore, we studied the association between VDSL at the diagnosis of melanoma and other germane prognostic factors. The population held in regard was composed of 154 patients with a diagnosis of melanoma between 2016 and 2019. These patients were retrospectively collected from our follow-up storage. We compared VDSL to clinical and pathological parameters (age, sex, tumour location, Breslow’s depth, Clark’s level, histological subtype, ulceration, et aliqua). Moreover, we recruited a control group with negative melanoma history. Mean and median of VDSL were significantly lower in the melanoma group. Instead, we found a negative association between melanoma and VDSL > 30 ng/L (OR 0.11; p < 0.0001). No correlation between VDSL and both Breslow’s depth and Clark’s level was discovered, but the VDSL comparison between thin (depth ≤ 1 mm) and thick tumours (depth > 1 mm) revealed a statistically significant difference (21.1 ± 8.2 ng/L vs 17.8 ± 8.1; p = 0.01). Moreover, VDSL were significantly lower in melanomas with mitotic rate ≥ 1/mm2 (22.1 ± 8.3 ng/L; p < 0007). Nevertheless, no connection was found between VDSL and both ulceration and positive sentinel nodes (p = 0.76; p = 0.74). Besides, our study revealed no association between VDSL and histological subtype (p = 0.161). Lower VDSL correlate with thick and high mitotic rate tumours. Future prospective studies would investigate if appropriate upkeep of suitable VDSL can decrease the risk of primary and recurrent melanoma diagnosis.

scholarly journals FRI0342 POST-EFFORT SYNOVIAL AND ENTHESIC RESPONSE IN PATIENTS WITH PSORIATIC ARTHRITIS IN REMISSION OF LOW DISEASE ACTIVITY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 765.2-765
Author(s):  
C. Guillén-Astete ◽  
P. Zurita-Prada ◽  
C. Urrego-Laurín
Keyword(s):  
Disease Activity ◽  
Power Doppler ◽  
Control Group ◽  
Healthy Population ◽  
Dominant Hand ◽  
Synovial Joint ◽  
Low Disease Activity ◽  
Post Exercise ◽  
Eular Recommendations ◽  
The Mean

Background:Synovial inflammation is part of the pathophysiological process of PsoA although it is considered secondary to enthesitis. It is of interest to assess the synovial joint, peritendinous and enthesic response of patients with PsoA in remission under controlled mechanical stress.Objectives:Our aim is to present our observational experience in patients with APso in remission or low activity of the disease exposed to controlled manual physical efforts adapted to the own grasping capacity of each subject.Methods:Before-after study of a consecutive cohort of patients with PsoA (CASPAR criteria), of at least two years d evolution and DAPSA≤14 at present. Patients with positive rheumatoid factor, patients with exclusively axial forms and patients on biological therapy at the beginning of the study were excluded. All patients underwent controlled basal ultrasound and post-dynamometric exercise (CAMRY EH101-17) of the dominant hand which included the carpus, MCFs, IFPs and IFDs of the 2nd to 5th fingers. The ultrasound findings were scored according to EULAR recommendations in grey scale (GS) and power Doppler (PD) for synovitis, enthesitis and tenosynovitis (maximum scores 71 and 87, respectively). For statistical analysis, comparisons were made with the results of their baseline and post-exercise ultrasound scores between subjects diagnosed with PsoA and controls. The Student’s T test was used for related and unrelated data according to correspondence.Results:Nineteen patients and controls were included, of which 73.7% were male. Mean age: 42.2 SD 6.6 and 42.21 SD 8.28, respectively. Basal DAPSA among patients: 7.26 SD 4.53. Mean traction strength of patients and controls: 23.8 SD 7.3 and 26.1 SD 6.9 kg, respectively (P=0.336). In the group of patients, the post exercise DAPSA had a mean of 7.52 SD 4.62 (P=0.021, with respect to the basal DAPSA). The mean total GS score in the patient group was 3.94 SD 2.36 and 7.31 SD 3.3, pre- and post-exercise, respectively (P<0.001). The mean total score in the PD study was 0.73 SD 0.73 and 2.57 SD 1.16, respectively (P<0.001). In patients with PsoA there were no detectable enthesic changes. In the control group, no ultrasound changes were statistically significant, although the score for tenosynovitis ranged from 0.1 SD 0.31 to 0.42 SD 0.6 (P=0.055).Conclusion:Patients with APso in clinical remission or low disease activity develop ultrasound changes after controlled exercise. These changes are appreciable in the joint synovium and tendon but not at an enthesic level. Although these changes are also detectable in a healthy population, their prevalence is much lower. Our interpretation is that control of the disease correlates with an absence of enthesic inflammatory activity although synovial susceptibility remains less evident. This reinforces the idea that PsoA is an inflammatory enthesitis with associated arthritis and not its opposite.Disclosure of Interests:None declared

Multisensory balance training for unsteady elderly people: A scoping review

2021 ◽  
pp. 1-9
Author(s):  
In-Gyu Yoo ◽  
Ji-Hye Do
Keyword(s):  
User Satisfaction ◽  
Web Of Science ◽  
Relevant Literature ◽  
Balance Training ◽  
The Elderly ◽  
Control Group ◽  
Training Methods ◽  
Multisensory Stimulation ◽  
Multisensory Training ◽  
Risk Of Falls

BACKGROUND: Posture control involves complex reactions of dynamic and static movements, and various sensory inputs. There is evidence that exercise using multisensory stimulation is moderately effective in improving the balance of the elderly. OBJECTIVE: The main purpose of this paper was to examine the existing literature to validate the effectiveness and applicability of multisensory stimulation training. METHODS: All relevant literature published as of June 1, 2020 in four prominent databases was searched (Embase, PubMed, PsycINFO, and Web of science) using the five-stage review framework proposed by Arksey and O’Malley. RESULTS: Multisensory stimulation training was more effective when vestibular and somatosensory were combined with visual stimuli, and differences in effectiveness compared to the effectiveness of existing treatments were confirmed. However, most of the reviewed papers are compared to simple strength training, and studies that compare the effects of multisensory stimulation training by setting a control group are still lacking. CONCLUSION: Further research is required to further elucidate the training conditions and treatment environment for multisensory training for the elderly at risk of falls and to provide strategies to improve treatment methods. In addition, a study that can evaluate user satisfaction in a way that best shows the treatment effect using qualitative research methods will be needed.

scholarly journals Effects of Cognicise-Neurofeedback on Health Locus of Control, Depression, and Quantitative Electroencephalography Alpha Asymmetry in Elderly Women

2021 ◽  
Vol 11 (7) ◽  
pp. 899
Author(s):  
Heewook Weon ◽  
Jieun Yoo ◽  
Jumhwa Yu ◽  
Miso Park ◽  
Haekyoung Son
Keyword(s):  
Locus Of Control ◽  
Elderly Women ◽  
Health Locus Of Control ◽  
Cognitive Activity ◽  
The Elderly ◽  
Control Group ◽  
Quantitative Electroencephalography ◽  
Alpha Asymmetry ◽  
Post Test ◽  
Experimental Group

Background: With an increase in the aged population, there is a growing concern regarding the care of the elderly. This study aims to identify effects of cognicise-neurofeedback on health locus of control, depression, and quantitative electroencephalography (QEEG) alpha asymmetry in elderly women. Methods: A quasi-experimental control group pre-test–post-test design was used. Korean women aged 65 years or over at a senior welfare center were randomly allocated to the control (n = 12) or experimental (n = 19) groups from July to October 2019. The intervention consisted of cognicise (exercise with intensified cognitive activity) and neurofeedback twice a week for 10 weeks. The locus of control and depression were measured via self-reported questionnaires. QEEG alpha asymmetry was measured using BrainMaster. Results: Depression significantly decreased in the experimental group (t = 4.113, p = 0.001), while internality in the locus of control significantly decreased in the control group (t = 3.023, p = 0.012). On the other hand, QEEG alpha asymmetry index differences in F3-F4 between the pre-test and post-test were not significant in the experimental group (t = 0.491, p = 0.629) or control group (t = 0.413, p = 0.678). Conclusions: Due to the coronavirus disease (COVID-19) pandemic, contact between the elderly and healthcare workers in the clinical practice field has become more restricted. These findings can help decrease negative emotions among elderly women in the community based on an integrated neuroscientific approach.

scholarly journals Corneal Biomechanical Parameters and Central Corneal Thickness in Glaucoma Patients, Glaucoma Suspects, and a Healthy Population

2021 ◽  
Vol 10 (12) ◽  
pp. 2637
Author(s):  
Mª. Ángeles del Buey-Sayas ◽  
Elena Lanchares-Sancho ◽  
Pilar Campins-Falcó ◽  
María Dolores Pinazo-Durán ◽  
Cristina Peris-Martínez
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Mean Difference ◽  
The Other ◽  
Control Group ◽  
Healthy Population ◽  
Diagnostic Categories ◽  
Significant Difference ◽  
Biomechanical Parameters ◽  
The Mean

Purpose: To evaluate and compare corneal hysteresis (CH), corneal resistance factor (CRF), and central corneal thickness (CCT), measurements were taken between a healthy population (controls), patients diagnosed with glaucoma (DG), and glaucoma suspect patients due to ocular hypertension (OHT), family history of glaucoma (FHG), or glaucoma-like optic discs (GLD). Additionally, Goldmann-correlated intraocular pressure (IOPg) and corneal-compensated IOP (IOPcc) were compared between the different groups of patients. Methods: In this prospective analytical-observational study, a total of 1065 patients (one eye of each) were recruited to undergo Ocular Response Analyzer (ORA) testing, ultrasound pachymetry, and clinical examination. Corneal biomechanical parameters (CH, CRF), CCT, IOPg, and IOPcc were measured in the control group (n = 574) and the other groups: DG (n = 147), FHG (n = 78), GLD (n = 90), and OHT (n = 176). We performed a variance analysis (ANOVA) for all the dependent variables according to the different diagnostic categories with multiple comparisons to identify the differences between the diagnostic categories, deeming p < 0.05 as statistically significant. Results: The mean CH in the DG group (9.69 mmHg) was significantly lower compared to controls (10.75 mmHg; mean difference 1.05, p < 0.001), FHG (10.70 mmHg; mean difference 1.00, p < 0.05), GLD (10.63 mmHg; mean difference 0.93, p < 0.05) and OHT (10.54 mmHg; mean difference 0.84, p < 0.05). No glaucoma suspects (FHG, GLD, OHT groups) presented significant differences between themselves and the control group (p = 1.00). No statistically significant differences were found in the mean CRF between DG (11.18 mmHg) and the control group (10.75 mmHg; mean difference 0.42, p = 0.40). The FHG and OHT groups showed significantly higher mean CRF values (12.32 and 12.41 mmHg, respectively) than the DG group (11.18 mmHg), with mean differences of 1.13 (p < 0.05) and 1.22 (p < 0.001), respectively. No statistically significant differences were found in CCT in the analysis between DG (562 μ) and the other groups (control = 556 μ, FHG = 576 μ, GLD = 569 μ, OHT = 570 μ). The means of IOPg and IOPcc values were higher in the DG patient and suspect groups than in the control group, with statistically significant differences in all groups (p < 0.001). Conclusion: This study presents corneal biomechanical values (CH, CRF), CCT, IOPg, and IOPcc for diagnosed glaucoma patients, three suspected glaucoma groups, and a healthy population, using the ORA. Mean CH values were markedly lower in the DG group (diagnosed with glaucoma damage) compared to the other groups. No significant difference was found in CCT between the DG and control groups. Unexpectedly, CRF showed higher values in all groups than in the control group, but the difference was only statistically significant in the suspect groups (FHG, GLD, and OHT), not in the DG group.

scholarly journals Virtual Reality Gait Training to Promote Balance and Gait Among Older People: A Randomized Clinical Trial

Geriatrics ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
Kyeongjin Lee
Keyword(s):  
Virtual Reality ◽  
The Elderly ◽  
Gait Training ◽  
Control Group ◽  
Timed Up And Go ◽  
Elderly Individuals ◽  
Functional Reach Test ◽  
Balance Ability ◽  
Standing Test ◽  
The One

Falls are the leading cause of injury and injury-related death in the elderly. This study evaluated the effect of virtual reality gait training (VRGT) with non-motorized treadmill on balance and gait ability of elderly individuals who had experienced a fall. Fifty-six elderly individuals living in local communities participated in this study. Subjects who met the selection criteria were randomly divided into a VRGT group (n = 28) and a control group (n = 28). The VRGT group received VRGT with non-motorized treadmill for 50 min a day for 4 weeks and 5 days a week. The control group received non-motorized treadmill gait training without virtual reality for the same amount of time as the VRGT group. Before and after the training, the one-leg-standing test, Berg Balance Scale, Functional Reach test, and Timed Up and Go test were used to assess balance ability, and the gait analyzer system was used to evaluate the improvement in gait spatiotemporal parameters. In the VRGT group, the balance ability variable showed a significant decrease in the one-leg-standing test and a significant improvement in the Timed Up and Go test. With respect to spatiotemporal gait parameters, velocity and step width decreased significantly in the VRGT group (p < 0.05), and stride length and step length were significantly improved in the VRGT group (p < 0.05). VRGT with non-motorized treadmill has been shown to improve balance and gait ability in the elderly. This study is expected to provide basic data on exercise programs for the elderly to prevent falls.

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