scholarly journals An Analysis of the NSW Midwives Data Collection over an 11-Year Period to Determine the Risks to the Mother and the Neonate of Induced Delivery for Non-Obstetric Indication at Term

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Padmini Raviraj ◽  
Aiat Shamsa ◽  
Jun Bai ◽  
Rajanishwar Gyaneshwar

Objective. To determine the risks of induced term delivery to the mother and neonate at different gestational ages in the absence of obstetric indications. Study Design. All deliveries in New South Wales (NSW) between 1998 and 2008 were reviewed from the MDC. Uncomplicated pregnancies which were induced for non-obstetric reasons after 37 completed weeks were reviewed. This was a retrospective, historical cohort study, and both maternal and neonatal outcomes were analysed and compared between different gestational age groups. Results. An analysis of the data shows that induction of labour after 37 completed weeks exposes the fetus and mother to different levels of risk at different gestations. Conclusion. In an uncomplicated pregnancy, induction of labour is associated with the highest rate of neonatal complication at 37 weeks as compared with rates at later gestations. With each ensuing week, the neonatal outcome improves. At 40 weeks the likelihood of neonatal intensive care admission, low Apgar scores, and perinatal death rate is at its lowest, and then there is a slight but not significant rise after 41 weeks. The likelihood of caesarean section is the lowest when inductions are carried out at 39 weeks and is the highest at 41 weeks and over.

2000 ◽  
Vol 68 (3) ◽  
pp. 1529-1534 ◽  
Author(s):  
Edward Y. Konadu ◽  
Feng-Ying C. Lin ◽  
Vô Anh Hó ◽  
Nguyen Thi Thanh Thuy ◽  
Phan Van Bay ◽  
...  

ABSTRACT Salmonella enterica serovar Paratyphi A O-specific polysaccharide (O-SP) was activated with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (CDAP) and bound to tetanus toxoid (TT) with adipic acid dihydrazide as a linker (SPA-TT1) or directly (SPA-TT2). In mice, these two conjugates elicited high levels of immunoglobulin G (IgG) anti-lipopolysaccharide (LPS) in serum with bactericidal activity (E. Konadu, J. Shiloach, D. A. Bryla, J. B. Robbins, and S. C. Szu, Infect. Immun. 64:2709–2715, 1996). The safety and immunogenicity of the two conjugates were then evaluated sequentially in Vietnamese adults, teenagers, and 2- to 4-year-old children. None of the vaccinees experienced significant side effects, and all had preexisting LPS antibodies. At 4 weeks after injection, there were significant increases of the geometric mean IgG and IgM anti-LPS levels in the adults and teenagers: both conjugates elicited a greater than fourfold rise in the IgG anti-LPS level in serum in ≥80% of the volunteers. SPA-TT2 elicited slightly higher, though not statistically significantly, levels of IgG anti-LPS than did SPA-TT1 in these age groups. Accordingly, only SPA-TT2 was evaluated in the 2- to 4-year-old children. On a random basis, one or two injections were administered 6 weeks apart to the children. No significant side effects were observed, and the levels of preexisting anti-LPS in serum were similar in children of all ages. A significant rise in the IgG anti-LPS titer was elicited by the first injection (P = 0.0001); a second injection did not elicit a booster response. Representative sera from all groups had bactericidal activity that could be adsorbed by S. enterica serovar Paratyphi A LPS.


2018 ◽  
Vol 58 (8) ◽  
pp. 1470
Author(s):  
J. S. Richards ◽  
M. A. Sladek ◽  
G. J. Lee

Reproduction is an important driver of profitability in commercial sheep flocks. Historically, Merino flocks have been run with a fixed age structure, ignoring individual merit and casting for age at a specific age. More recently, research has focussed on utilising the variation within age groups by keeping productive older ewes longer and culling less productive ewes earlier. Previous studies have also examined the effect of age on reproduction and the impact of reproduction status on productivity, but little research has been conducted on cumulative effects of reproductive performance on later productivity, reproduction and health. The present study examined the impact of higher lifetime reproduction on other key production and fitness traits in older ewes run under commercial conditions. Data were collected from two commercial wool-producing properties in the South West Slopes and the Central West Plains of New South Wales during 2009–2011. Reproduction, fleece measurements, bodyweight and condition and dental health were recorded during the study. The results showed that age had a bigger effect on productivity and dental health than did cumulative lifetime reproduction. Environment and genetics determined the level of impact, with minimal loss in productivity from increased age of animals occurring in the South West Slopes flock, whereas the Central West Plains flock would appear to require closer monitoring of productivity as ewes aged. The data collected did not allow separation of the genetic and environmental influences within the study. Retaining animals with a higher reproductive performance past normal culling age does not necessarily result in reduction of productivity or ewe health, but this must be monitored.


2020 ◽  
Author(s):  
Quyen G To ◽  
Mitch J Duncan ◽  
Anetta Van Itallie ◽  
Corneel Vandelanotte

BACKGROUND Physical activity is an important health behavior, due to its association with many physical and mental health conditions. During distressing events, such as the COVID-19 pandemic, there is a concern that physical activity levels may be negatively impacted. However, recent studies have shown inconsistent results. Additionally, there is a lack of studies in Australia on this topic. OBJECTIVE The aim of this study is to investigate changes in physical activity reported through the 10,000 Steps program and changes in engagement with the program during the COVID-19 pandemic. METHODS Data between January 1, 2018, and June 30, 2020, from registered members of the 10,000 Steps program, which included 3,548,825 days with step data, were used. The number of daily steps were logged manually by the members or synced automatically from their activity trackers connected to the program. Measures on program usage were the number of new registered members per day, the number of newly registered organizations per day, the number of steps logged per day, and the number of step entries per day. Key dates used for comparison were as follows: the first case with symptoms in Wuhan, China; the first case reported in Australia; the implementation of a 14-day ban for noncitizens arriving in Australia from China; the start of the lockdown in Australia; and the relaxing of restrictions by the Australian Government. Wilcoxon signed-rank tests were used to test for significant differences in number of steps between subgroups, between engagement measures in 2019 versus 2020, and before and after an event. RESULTS A decrease in steps was observed after the first case in Australia was reported (1.5%; <i>P</i>=.02) and after the start of the lockdown (3.4%; <i>P</i>&lt;.001). At the time that the relaxing of restrictions started, the steps had already recovered from the lockdown. Additionally, the trends were consistent across genders and age groups. New South Wales, Australian Capital Territory, and Victoria had the greatest step reductions, with decreases of 7.0% (<i>P</i>&lt;.001), 6.2% (<i>P</i>=.02), and 4.7% (<i>P</i>&lt;.001), respectively. During the lockdown, the use of the program increased steeply. On the peak day, there were more than 9000 step entries per day, with nearly 100 million steps logged per day; in addition, more than 450 new users and more than 15 new organizations registered per day, although the numbers decreased quickly when restrictions were relaxed. On average per day, there were about 55 new registered users (<i>P</i>&lt;.001), 2 new organizations (<i>P</i>&lt;.001), 25.6 million steps (<i>P</i>&lt;.001), and 2672 log entries (<i>P</i>&lt;.001) more in 2020 compared to the same period in 2019. CONCLUSIONS The pandemic has had negative effects on steps among Australians across age groups and genders. However, the effect was relatively small, with steps recovering quickly after the lockdown. There was a large increase in program usage during the pandemic, which might help minimize the health impact of the lockdown and confirms the important role of physical activity programs during times of distress and lockdowns.


2021 ◽  
Vol 5 (1) ◽  
pp. 71-87 ◽  
Author(s):  
Jane Ellis

This study examined the effects of the Junior Rock Music Academy (JRMA) on participants’ (N = 39) confidence and self-esteem. The JRMA was a widening participation Saturday music programme developed to reduce the influences of poverty on educational underachievement for young people (10–18 years) from poorer families across South East Wales. Participants’ confidence and self-esteem scores reported a significant rise, with no significant difference reported between genders or age groups. Participants (N = 5), programme tutors (N = 3) and participant parents/guardians (N = 4) were interviewed using semi-structured interviews to establish the fidelity of the structure and content of the intervention. The impact of JRMA on the psychosocial, cultural and emotional characteristics of participants and their parents/guardians as barriers to educational attainment and preparedness to thrive in education are discussed; these include enhanced cognitive development, social and emotional skills and learner motivation.


PEDIATRICS ◽  
1981 ◽  
Vol 68 (1) ◽  
pp. 122-130
Author(s):  
Alistair G. S. Philip ◽  
George A. Little ◽  
Denise R. Polivy ◽  
Jerold F. Lucey

Since 1976 a computerized data base has been used to store information on babies admitted to two intensive care nurseries serving the Vermont/New Hampshire region. The data base now allows reporting "neonatal" mortality by birth weight/gestational age (BW/GA) groupings for 1976-1979. For all BW/GA groups, except the most immature infants, there has been marked improvement compared to data gathered in the sixties (ie, mortality has decreased). These data are probably applicable to most other centers providing neonatal intensive care. The use of BW/GA categories provides the most reliable way of objectively comparing statistics from one center to another. Differences between two centers were observed when birth weight specific rates were used, but were largely abolished by using BW/GA groups. Data gathered in this way will be increasingly important for comparisons between centers and across years and when evaluating the effectiveness of new therapeutic interventions.


1965 ◽  
Vol 16 (6) ◽  
pp. 981 ◽  
Author(s):  
J Lax ◽  
Turner H Newton

The influence of sex, strain, location, and age of ewe on survival rate to weaning of single-born Merino lambs has been examined in two sets of data: the strain trial, involving five strains run without selection at each of three locations (Cunnamulla, Qld.; Armidale, on the northern tablelands of New South Wales; Deniliquin, in the Riverina area of New South Wales), with six age groups of ewes; and the same five strains later included in selection groups at Armidale with seven age groups of ewes. The strain trial at Armidale ran mainly on native, and the selection groups mainly on improved pastures. Female lambs had a higher survival rate than either castrated or entire males, the differences in lambs weaned per lamb born being 0.03 and 0.04 respectively. No strain differences could be regarded as statistically significant, and neither could the strain x location interaction in the strain trial. Mean survival rates for the strains ranged from 0.673 to 0.786 on the Armidale native and from 0.802 to 0.850 on the Armidale improved pasture, from 0.746 to 0.859 at Cunnamulla, and from 0.838 to 0.894 at Deniliquin. The strains did not rank consistently in the same order. Location had a marked effect on survival rate, the means being 0.744 for the native and 0.824 for the improved pasture at Armidale, 0.810 at Cunnamulla, and 0.868 at Deniliquin. Age of ewe had a marked influence in the poorest environment (Armidale native pasture), survival rate rising with age and later falling sharply. The effect was less marked in the intermediate environments (Armidale improved pasture and Cunnamulla) and negligible at Deniliquin. The patterns at Cunnamulla and Deniliquin are confirmed by data from other experiments on these stations. Survival rate is one component of number of lambs weaned. The other component, number of lambs born, has a higher mean value at Deniliquin than Cunnamulla, but shows a strong association with age of ewe in both environments. Number of lambs born responds rapidly to selection, but no information is yet available concerning the likely response in survival rate. If improvement in environment can raise the survival rate, particularly in the youngest and oldest ewes, then selection for number of lambs born, combined with improved environment, should lead to a marked rise in the number of lambs weaned.


1968 ◽  
Vol 8 (33) ◽  
pp. 425 ◽  
Author(s):  
EJ Sparke ◽  
DR Lamond

This paper reports an experiment examining the effect of age and protein supplementation on growth and fertility of Shorthorn-Devon cross heifers grazing natural pastures in the summer rainfall, subtropical environment of the Upper Clarence valley, north-eastern New South Wales. Heifers born over the period October to January 1963-64 were weaned in June 1964 and allotted at random within age groups (by month of birth) to a supplemented or non-supplemented treatment. The supplemented heifers were given linseed meal during the dry winter period each year from 1964 to 1966 inclusive (May-June to September-October). They were weighed each month and joined with bulls in the early summer of 1965 (2 years) and 1966 (3 years). They were examined for pregnancy in the autumn, and their calves were identified at birth. Supplemented heifers gained weight throughout and non-supplemented heifers generally lost weight in the winter periods. At two years fertility was closely related to liveweight at joining in supplemented heifers, but not in others. Heifers born in January gave the poorest reproductive performance, as the two supplemented ones that became pregnant in 1965 died at calving, and two-thirds of the non-supplemented ones were still empty after joining as 3-year-olds. The advantage of high 2-year-old fertility gained by heifers born in October and November, due to their greater size at joining, was partly offset by low fertility when lactating the following year. It is concluded that a decision as to whether a heifer should be supplemented during a period of nutritional stress prior to joining ought to be based on the probability of her reaching a prescribed target weight at joining as a result of receiving the supplement. The target weight for lactating heifers was at least 100 Ib higher than for dry hdfers. The results also indicate specific areas for further research.


Midwifery ◽  
2015 ◽  
Vol 31 (5) ◽  
pp. 526-531 ◽  
Author(s):  
Louise L. Kjeldsen ◽  
Mette Sindberg ◽  
Rikke D. Maimburg

1982 ◽  
Vol 92 (2) ◽  
pp. 213-223 ◽  
Author(s):  
A. I. FRANKEL ◽  
W. W. WRIGHT

A comprehensive study has been made of the hemicastrated rat from 2 to 12 months of age in order to define what might represent an ideal model in which to study testicular regulation. Although there was no compensatory hypertrophy in the remaining testis of the mature hemicastrated rat, levels of plasma testosterone fell significantly within 4 h after surgery in all age groups older than 3 months, and were restored to normal levels almost immediately, usually within 8 h. There were no significant changes in LH and prolactin, and the significant rise in FSH was sufficiently delayed (2 days or more) to suggest that none of these three hormones was implicated in any obvious way in the compensatory restoration of plasma testosterone levels. Although a single testis was capable of maintaining normal plasma testosterone concentrations, its response to human chorionic gonadotrophin at 24 h after hemicastration was significantly less than that of intact animals, suggesting that the single testis was functioning at near-maximal capacity. The hormonal responses to repetitive blood sampling and to sham-surgery simulated the response to hemicastration remarkably. However, these responses were never statistically significant in within-group analysis, and therefore did not obscure the significant fall of plasma testosterone levels in response to hemicastration. The basic mechanism by which plasma testosterone is restored in the hemicastrated rat is still unknown, but the options have been narrowed.


Sign in / Sign up

Export Citation Format

Share Document