Epidemiology and Clinical Features of Adult Patients with Psoriasis in Malaysia: 10-Year Review from the Malaysian Psoriasis Registry (2007–2016)

Background.Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the general population.Aim.To evaluate the epidemiology and clinical characteristics of patients with psoriasis who seek treatment in outpatient dermatology clinics throughout hospitals in Malaysia.Materials and Methods.Data were obtained from the Malaysian Psoriasis Registry (MPR). All patients (aged 18 and above) who were notified to the registry from July 2017 to December 2017 were included in this study.Results.Among 15,794 patients, Malays were the most common (50.4%), followed by Chinese (21.4%), Indian (17.6%), and others (10.6%). The mean age onset of psoriasis for our study population was 35.14 ± 16.16 years. Male to female ratio was 1.3 : 1. 23.1% of patients had positive family history of psoriasis. The most common clinical presentation was chronic plaque psoriasis (85.1%), followed by guttate psoriasis (2.9%), erythrodermic psoriasis (1.7%), and pustular psoriasis (1.0%). Majority of our patients (76.6%) had a mild disease with BSA < 10%. 57.1% of patients had nail involvement, while arthropathy was seen in 13.7% of patients. Common triggers of the disease include stress (48.3%), sunlight (24.9%), and infection (9.1%). Comorbidities observed include obesity (24.3%), hypertension (25.6%), hyperlipidemia (18%), diabetes mellitus (17.2%), ischaemic heart disease (5.4%), and cerebrovascular disease (1.6%). The mean DLQI (Dermatology Life Quality Index) was 8.5 ± 6.6. One-third (33.1%) of the patients had a DLQI score of more than 10, while 14.2% of patients reported no effect at all.Conclusion.Our study on the epidemiological data of adult patients with psoriasis in Malaysia showed a similar clinical profile and outcome when compared to international published studies on the epidemiology of psoriasis.

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Effects of the COVID-19 Pandemic on the Epidemiology of Knee and Shoulder Arthroscopy

INQUIRY The Journal of Health Care Organization Provision and Financing ◽

10.1177/00469580211056037 ◽

2021 ◽

Vol 58 ◽

pp. 004695802110560

Author(s):

Krystian Kazubski ◽

Łukasz Tomczyk ◽

Piotr Morasiewicz

Keyword(s):

Hospital Stay ◽

Shoulder Arthroscopy ◽

Demographic Data ◽

Epidemiological Data ◽

University Hospital ◽

Female Ratio ◽

Duration Of Hospital Stay ◽

The Mean ◽

Orthopedic Patients ◽

Male To Female

The purpose of our study was to comprehensively assess the effect of the COVID-19 pandemic on knee and shoulder arthroscopy performed in an orthopedic department of a university hospital in Poland. This study compared the data on all shoulder and knee arthroscopy procedures performed in two different periods: The period of the COVID-19 pandemic in Poland (from March 4, 2020, to October 15, 2020) and the corresponding period prior to the pandemic (March 4, 2019, to October 15, 2019). The study evaluated epidemiological data, demographic data, and hospital stay duration. The total number of arthroscopy procedures conducted in the evaluated period in 2020 was approximately 8.6% higher than that in the corresponding 2019 period. The mean duration of hospital stay for orthopedic patients after their knee or shoulder arthroscopy was 3.1 days in 2020 and 2.8 days in 2019. Our study revealed the mean age of arthroscopy patients during the pandemic to be lower at 48.4 years than the 51.2 years recorded in 2019. The male-to-female ratio was shown to be lower at .85 during the pandemic, having decreased from 1.5 in 2019. The COVID-19 pandemic did not reduce the number of arthroscopy performed at our center, and the mean age of the patients did not change. However, the pandemic had a marked effect on the mean duration of hospital stay and male-to-female ratio.

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Clinico-epidemiological study of childhood psoriasis

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v10i2.32710 ◽

2017 ◽

Vol 10 (2) ◽

pp. 119 ◽

Cited By ~ 1

Author(s):

Mohammed Saiful Islam Bhuiyan ◽

A. S. M. Zakaria ◽

Abida Sultana ◽

A. K. M. Zayedul Haque ◽

Sabbir Muhammad Shawkat

Keyword(s):

Epidemiological Study ◽

Plaque Psoriasis ◽

Epidemiological Data ◽

Common Type ◽

Pustular Psoriasis ◽

Joint Involvement ◽

Psoriasis Plaque ◽

Erythrodermic Psoriasis ◽

The Mean ◽

Nail Involvement

The clinico-epidemiological data of 276 childhood psoriasis were studied. The mean age was 7.64 years (range 1 day to 15 years). There was no complain of any discomfort in 198 cases. Itching was present in 67 cases and burning in 11 cases. Plaque psoriasis was the most common type (68.8%) followed by guttate (18.8%). Erythrodermic and pustular psoriasis were found in 2.2% and 1.5% cases. Scalp was the most frequently affected site (75.36%) followed by extensors of extremities (41.3%), trunk (37.7%), palm and/or sole (13.0%) and diaper area (11.6%). Nail involvement was found only in 8%, joint was affected in 3.6% and only 2.2% children with psoriasis were erythrodermic. In Bangladeshi children with psoriasis, plaque is the most common type and scalp is the mostly affect site. Nail and joint involvement is less common. Pustular and erythrodermic psoriasis is rare.

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Chronic Urticaria and Its Impact on the Quality of Life of Nepalese Patients

Dermatology Research and Practice ◽

10.1155/2020/6694191 ◽

2020 ◽

Vol 2020 ◽

pp. 1-5

Author(s):

Sushil Paudel ◽

Niraj Parajuli ◽

Rabindra Prasad Sharma ◽

Sudip Dahal ◽

Sudarshan Paudel

Keyword(s):

Quality Of Life ◽

Chronic Urticaria ◽

Demographic Data ◽

Life Quality ◽

Well Being ◽

Female Ratio ◽

Principle Component ◽

The Mean ◽

The Impact

Chronic urticaria (CU) is a skin condition characterized by sudden and recurrent episodes of wheals, angioedema, or both and commonly associated with itching for a duration of more than six weeks. The available data indicate that urticaria markedly affects both objective functioning and subjective well-being of patients. A review of patients’ records with chronic urticaria attending Civil Service Hospital from January 2018 to December 2019 was done. A detailed demographic data of all patients with chronic urticaria was also retrieved. Dermatology Life Quality Index questionnaire (DLQI) Nepalese version was used for the assessment of the impact of disease on life quality. Mann–Whitney U-test was applied to compare means, and principle component analysis for factor analysis was used. A total of 149 patients were included, with a male-to-female ratio of 1 : 1.9. The mean age of the study population was 32.86 ± 12.837 years. The mean DLQI score was 8.30 ± 6.73 with men having a significantly greater score than women ( p < 0.02 ). DLQI scores negatively correlated with age ( p < 0.01 ). There was a high internal consistency among items (Cronbach’s alpha 0.89), and all items had satisfactory correlation with each other as well. Principle component extraction revealed that there were two underlying factors in the DLQI questionnaire on measuring quality of life in chronic urticaria. Males had a greater impairment in quality of life than females due to chronic urticaria. Most severe impairment was seen in symptoms/feelings subdomain. It also revealed that there were two different underlying factors in DLQI questionnaire.

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Effects of the COVID-19 Pandemic on the Epidemiology of Knee and Shoulder Arthroscopy Procedures in a University Hospital Department in Poland

10.21203/rs.3.rs-146656/v1 ◽

2021 ◽

Author(s):

Krystian Kazubski ◽

Łukasz Tomczyk ◽

Piotr Morasiewicz

Keyword(s):

Hospital Stay ◽

Shoulder Arthroscopy ◽

Demographic Data ◽

Epidemiological Data ◽

University Hospital ◽

Female Ratio ◽

Duration Of Hospital Stay ◽

The Mean ◽

Orthopedic Patients ◽

Male To Female

Abstract Background: The purpose of our study was to comprehensively assess the effect of the COVID-19 pandemic on knee and shoulder arthroscopies performed in an orthopedic department of a university hospital in Poland.Methods: This study compared the data on shoulder and knee arthroscopy procedures performed in two different periods: the period of the COVID-19 pandemic in Poland (from March 4, 2020 to October 15, 2020) and the corresponding period prior to the pandemic (March 4, 2019–October 15, 2019). The study evaluated epidemiological data, demographic data, and hospital stay duration.Results: The total number of arthroscopy procedures conducted in the evaluated period in 2020was approximately 8.6% higher than that in the corresponding 2019 period.The mean duration of hospital stay for orthopedic patients after their knee or shoulder arthroscopy was 3.1 days in 2020 and 2.8 days in 2019. Our study revealed the mean age of arthroscopy patients during the pandemic to be lower at 48.4 years than the 51.2 years recorded in 2019.The male-to-female ratio was shown to be lower at 0.85 during the pandemic, having decreased from 1.5 in 2019Conclusions: The COVID-19 pandemic did not reduce the number of arthroscopies performed at our center and the mean age of the patients did not change. However, the pandemic had a marked effect on the mean duration of hospital stay and male-to-female ratio.

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Mandibular Fractures: A Comparative Analysis between Different Age Groups of Patients Seen at Kantipur Dental College Teaching Hospital and Research Center

Journal of Oral & Dental Health ◽

10.33140/jodh/01/02/00004 ◽

2017 ◽

Vol 1 (2) ◽

Keyword(s):

Teaching Hospital ◽

Age Groups ◽

Young Patients ◽

College Teaching ◽

Adult Patients ◽

Research Center ◽

Mandibular Fractures ◽

Female Ratio ◽

Male Female Ratio ◽

The Mean

Objective: The purpose of this study was to compare the differences between mandibular fractures in different age group of patients. Material and Methods: Patients treated at the Oral and Maxillofacial Department of Kantipur dental college teaching hospital and research center during a two-year period between 2013 and 2015 were retrospectively evaluated with respect to age groups, gender, etiology, localization and type of fractures, treatment methods and complications. Results: 532 patients were included in the study, 370 (70%) males and 162 (30%) females, with a total of 744 mandibular fractures. The mean age of young patients was 10, with a male-female ratio of 2:1. The mean age of adult patients was 28, with a male-female ratio of 3:1. The most common causes of injury were falls (65%) in young patients and traffic accidents (38%) in adults. The most common fracture sites were the symphysis (35%) and condyle (36%) in young patients, and the symphysis in adults (36%). Mandibular fractures were generally treated by arch bar and intermaxillary fixation in both young (67%) and adult (39%) patients, and 43% of the adult patients were treated by open reduction and internal fixation. Conclusion: There was a similar gender, monthly and type of treatment distribution in both young and adult patients in the hospital. However, there were differences regarding age, etiology and fracture site. These findings between young and adult patients are broadly similar to those from other studies. Analysis of small differences may be an important factor in assessing educational and socioeconomic environments.

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Changing Trends in ITP Management from 1995 to 2007: An Interim Report from the UK Paediatric ITP Registry.

Blood ◽

10.1182/blood.v112.11.3411.3411 ◽

2008 ◽

Vol 112 (11) ◽

pp. 3411-3411

Author(s):

John D. Grainger ◽

Joanne L Rees ◽

Marie Reeves ◽

Paula HB Bolton-Maggs

Keyword(s):

Severe Disease ◽

Epidemiological Data ◽

Registry Data ◽

Newly Diagnosed ◽

Mild Disease ◽

Changing Trends ◽

The Mean ◽

Bleeding Score ◽

Set Up ◽

The Uk

Abstract A UK national paediatric ITP registry (www.uk-itp.org) was set up in January 2007 designed to collect data from all newly diagnosed ITP over at least a subsequent 10 year period. By May 2008, 62 hospitals had recruited 114 children. Details about epidemiology, presentation and management were entered into the registry. The preliminary data presented was compared with results from two national UK audits in 1995 and 2000. In this first analysis, 68% children had mild, 29% had moderate and 3% had severe disease as defined by a modified Buchanan bleeding score. The mean platelet counts at diagnosis for the groups were 18.3, 10.1 and 8.0 respectively. Bruising (mean 86.7%) and purpura (mean 73.0%) were the most common bleeding manifestations in ITP followed by epistaxis (mean 22.0%) and oral bleeding (mean 18.7%). Other bleeding sites such as bleeding from the gastrointestinal tract and menorrhagia are much less common and there were no intracranial bleeds. Children with mild disease have fewer bleeding sites (mean 1.3), compared to 2.3 with moderate and 3.0 for severe disease. These data are very similar to those reported in the previous national audits. The proportion of children receiving platelet raising treatment was noted to decrease from 60.5% in 1995 to 37.8% in 2000. The current 2007 registry data shows a continued decrease in treatment to 20% of all the children. In the mild category 11.8% were treated, compared to 31% of the moderate and all of the severe. Of those receiving treatment 75% were treated with steroids alone, 15% IVIG alone and 10% received combination IVIG and steroids. Forty seven percent were admitted to hospital with a median duration of stay at 2 days. In summary the current UK Paediatric ITP Registry data shows similar epidemiological data to the previous UK audits. The previous observed decrease in treatment and adoption of a “watch and monitor” policy has increased to the extent that 80% of children do not receive platelet raising therapy. Continued recruitment and analysis is required to provide more data on which patients can safely avoid platelet raising therapy and which patients require prompt treatment to raise their platelet count.

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Dermatological life quality index in psoriasis out patients: the changing trend

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20190239 ◽

2019 ◽

Vol 5 (1) ◽

pp. 170

Author(s):

K. Parimalam ◽

S. Sanjeetha Fathima

Keyword(s):

Negative Impact ◽

Patient Adherence ◽

Psoriasis Patient ◽

Life Quality ◽

Cross Sectional Study ◽

Chronic Inflammatory Disease ◽

Joint Involvement ◽

Cross Sectional ◽

Female Ratio ◽

Mild Disease

Background: Psoriasis is a chronic inflammatory disease characterized by remissions and exacerbations, having great impact on social and psychological aspects. From mild plaque psoriasis to more severe pustular and erythrodermic forms with or without joint involvement, is known to have a negative impact on QOL (Quality of Life). Appropriate treatment will improve both disease outcome and QOL in patients. The objective of the study was to assess QOL in psoriasis patient of different age group, type, duration and severity of disease, and their response to this assessment.Methods: A cross sectional study was done with pretested DLQI questionnaire on 101 psoriasis patients, in a government hospital. Interpretation of score and impact on QOL was done and graded as mild, moderate, considerable, severe and very severe.Results: In our study, females outnumbered males with male female ratio of 1:1.5. The mean age 39.56±16.029 years. No significant association was noted between grade of affection and demographic variants. Most of them had moderate impact on QOL. QOL was worst affected in patients <5 years of disease duration. 85% of the patients felt happy & 15% felt neutral on being evaluated by this questionnaire.Conclusions: It is suggested that DLQI is assessed in all new/patients with less than 5 years of disease. Appropriate systemic/photo therapy to be initiated even in mild disease if there is negative impact on the QOL. Assessment of QOL strengthens the doctor-patient rapport and improves better patient adherence to therapy and achieves faster and better control of the disease.

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The Epidemiology of Cystic Fibrosis in Arab Countries: A Systematic Review

SN Comprehensive Clinical Medicine ◽

10.1007/s42399-021-00756-z ◽

2021 ◽

Vol 3 (2) ◽

pp. 490-498

Author(s):

Samer Hammoudeh ◽

Wessam Gadelhaq ◽

Yahya Hani ◽

Nadia Omar ◽

Darine El Dimassi ◽

...

Keyword(s):

Cystic Fibrosis ◽

United Arab Emirates ◽

Autosomal Recessive ◽

Arab World ◽

Life Quality ◽

Epidemiological Data ◽

Arab Countries ◽

Inclusion Criteria ◽

Multiple Systems ◽

Endocrine Symptoms

AbstractCystic fibrosis (CF) is a genetic autosomal recessive disease that involves multiple systems. Both life quality and expectation are affected by the debilitating multi-system involvement of the disease which includes pulmonary, gastrointestinal, reproductive, and endocrine symptoms. Very few studies have covered the epidemiological aspects of the disease among Arab countries. To systematically review the available epidemiological literature on cystic fibrosis in order to describe the epidemiological state of this disease in the Arab world, this review used PubMed to search for relevant articles related to patients with cystic fibrosis, with no restriction on gender or age. Google scholar and the snowballing technique were used to locate further articles. A total of 17 articles met the inclusion criteria for this review. These articles were from Bahrain, Egypt, Jordan, Kuwait, Morocco, Oman, Saudi Arabia, Tunisia, and the United Arab Emirates. The articles scored 1.5–6.5 out of 8 on the quality assessment. The epidemiological data reported varied based on country and type of study. The establishment of CF registries is definitely a priority in the region, as well as the need for more research involving CF patients particularly those involving the epidemiological and clinical characteristics of these patients.

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AB0478 CORONARY ATHEROSCLEROSIS IN BEHCET’S DISEASE

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.3609 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 1537.1-1537

Author(s):

R. Goloeva ◽

Z. Alekberova

Keyword(s):

Behçet’S Disease ◽

Coronary Atherosclerosis ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Subclinical Atherosclerosis ◽

Disease Onset ◽

Atherogenic Index ◽

Female Ratio ◽

Behcet's Disease ◽

The Mean

Background:Behcet’s disease (BD) is systemic vasculitis, which affects all types and sizes of vessels. Increased carotid intima-media thickness (IMT) is parameter associated with subclinical atherosclerosis.Objectives:To determine the prevalence of atherosclerosis in pts with BD.Methods:95 BD pts were evaluated and 45 healthy controls matched for age and gender.IMT was assessed by high-resolution B-mode ultrasonography. Serum concentration of high-sensitivity C-reactive protein (hs CRP) was measured by immunonephelometric assay (BN-100 Analyzer; Dade Behring). Lipid profile evaluation included total cholesterol, TGs, HDL, LDL and atherogenic index.Results:The male-to-female ratio was 3,7:1, the mean age of pts was 29.7 (23-35) yrs, the mean age at the disease onset - 19,9 (14-25) yrs, the mean disease duration - 9,6 (4-15) yrs.Conclusion:Coronary atherosclerosis in BD pts was lower than what we expected. The thinning IMT may be one of the risk factors for aneurysm formation in pts with BD.Disclosure of Interests:None declared

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Attitudes about Testicular Self-Examination among Polish Males

Biology ◽

10.3390/biology10030239 ◽

2021 ◽

Vol 10 (3) ◽

pp. 239

Author(s):

Tomasz Milecki ◽

Natalia Majchrzak ◽

Adam Balcerek ◽

Maciej Rembisz ◽

Michał Kasperczak ◽

...

Keyword(s):

Risk Factors ◽

General Practitioner ◽

Testicular Cancer ◽

Family Member ◽

Malignant Tumor ◽

Epidemiological Data ◽

Access To Information ◽

The Mean ◽

Original Survey ◽

Self Examination

Introduction: Epidemiological data indicate an increased incidence of testicular cancer (TC), making it the most common malignant tumor in men from aged 15–45. Oncological and urological associations recommend that men with specific TC risk factors should regularly perform a testicular self-exam (TSE). The aim of the study was to discover the attitudes among Polish males regarding TSE and factors (environmental, social, educational) that affect intention to perform TSE. Methods: An original survey containing 21 questions was used to conduct a study among the Polish branch of VW (Volkswagen Poland) employees. Results: A total of 522 fully completed questionnaires were collected. The mean age of the surveyed respondents was 32 years. Information about TC and how to perform TSE was obtained by 34.4% (n = 185) of the men. It was shown that the following factors increase men’s intention to perform TSE: TC in their family member (p < 0.05; HR = 5.9; 95% Cl: 1.5–23.0), GP’s(General Practitioner) recommendations (p < 0.001; HR = 6.8; 95% Cl: 3.2–14.3), concern expressed by their partner (p < 0.001; HR = 3.3; 95% Cl: 2.1–5.3), and social campaigns (p < 0.001; HR = 2.6; 95% Cl: 1.5–4.6). Conclusions: Approximately half of young polish males do not perform TSE. Access to information on TC prevention is limited. Further action is needed to improve men’s awareness of TC and TSE.

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