scholarly journals Correlation between Mitochondrial Dysfunction, Cardiovascular Diseases, and Traditional Chinese Medicine

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Li Zhu ◽  
Zhigang Chen ◽  
Keli Han ◽  
Yilin Zhao ◽  
Yan Li ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Mitochondrial Dysfunction ◽  
Mitochondrial Function ◽  
Regulatory Effect ◽  
Stress Regulation ◽  
Dna Mutations ◽  
Mitochondrial Biosynthesis ◽  
Antioxidant Stress ◽  
The Relationship

Cardiovascular disease (CVD) is the number one threat that seriously endangers human health. However, the mechanism of their occurrence is not completely clear. Increasing studies showed that mitochondrial dysfunction is closely related to CVD. Possible causes of mitochondrial dysfunction include oxidative stress, Ca2+ disorder, mitochondrial DNA mutations, and reduction of mitochondrial biosynthesis, all of which are closely related to the development of CVD. At present, traditional Chinese medicine (TCM) is widely used in the treatment of CVD. TCM has the therapeutic characteristics of multitargets and multipathways. Studies have shown that TCM can treat CVD by protecting mitochondrial function. Via systematic literature review, the results show that the specific mechanisms include antioxidant stress, regulation of calcium homeostasis, antiapoptosis, and regulation of mitochondrial biosynthesis. This article describes the relationship between mitochondrial dysfunction and CVD, summarizes the TCM commonly used for the treatment of CVD in recent years, and focuses on the regulatory effect of TCM on mitochondrial function.

The impact of Traditional Chinese Medicine on mitophagy in disease models

2021 ◽  
Vol 27 ◽  
Author(s):  
Li-Ping Yu ◽  
Ting-Ting Shi ◽  
Yan-Qin Li ◽  
Jian-Kang Mu ◽  
Ya-Qin Yang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Molecular Mechanisms ◽  
Human Diseases ◽  
Regulatory Mechanisms ◽  
Disease Models ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

: Mitophagy plays an important role in maintaining mitochondrial quality and cell homeostasis through the degradation of damaged, aged, and dysfunctional mitochondria and misfolded proteins. Many human diseases, particularly neurodegenerative diseases, are related to disorders of mitochondrial phagocytosis. Exploring the regulatory mechanisms of mitophagy is of great significance for revealing the molecular mechanisms underlying the related diseases. Herein, we summarize the major mechanisms of mitophagy, the relationship of mitophagy with human diseases, and the role of traditional Chinese medicine (TCM) in mitophagy. These discussions enhance our knowledge of mitophagy and its potential therapeutic targets using TCM.

scholarly journals The Relationship between Traditional Chinese Medicine and Modern Medicine

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Jingcheng Dong
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Acupuncture Treatment ◽  
Basic Structure ◽  
Modern Medicine ◽  
Chinese Herbs ◽  
Pulse Diagnosis ◽  
Massage Treatment ◽  
Acupuncture Anesthesia ◽  
The Relationship

The essence of the traditional Chinese medicine has always been the most advanced and experienced therapeutic approach in the world. It has knowledge that can impact the direction of future modern medical development; still, it is easy to find simple knowledge with mark of times and special cultures. The basic structure of traditional Chinese medicine is composed of three parts: one consistent with modern medicine, one involuntarily beyond modern medicine, and one that needs to be further evaluated. The part that is consistent with modern medicine includes consensus on several theories and concepts of traditional Chinese medicine, and usage of several treatments and prescriptions of traditional Chinese medicine including commonly used Chinese herbs. The part that is involuntarily beyond modern medicine contains several advanced theories and important concepts of traditional Chinese medicine, relatively advanced treatments, formula and modern prescriptions, leading herbs, acupuncture treatment and acupuncture anesthesia of traditional Chinese medicine that affect modern medicine and incorporates massage treatment that has been gradually acknowledged by modern therapy. The part that needs to be further evaluated consists not only the knowledge of pulse diagnosis, prescription, and herbs, but also many other aspects of traditional Chinese medicine.

scholarly journals Ischemia-Reperfusion Injury in Peripheral Artery Disease and Traditional Chinese Medicine Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Zenghui Liang ◽  
Wentao Zhang ◽  
Tianyi Zhu ◽  
Yunsong Li ◽  
Pengkai Cao ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Mitochondrial Dysfunction ◽  
Reperfusion Injury ◽  
Peripheral Artery Disease ◽  
Ischemia Reperfusion Injury ◽  
Cell Damage ◽  
Ischemia Reperfusion ◽  
Peripheral Artery ◽  
Artery Disease

Peripheral artery disease (PAD) is a serious public health issue, characterized by circulation disorder of the lower extreme that reduces the physical activity of the lower extremity muscle. The artery narrowed by atherosclerotic lesions initiates limb ischemia. In the progression of treatment, reperfusion injury is still inevitable. Ischemia-reperfusion injury induced by PAD is responsible for hypoxia and nutrient deficiency. PAD triggers hindlimb ischemia and reperfusion (I/R) cycles through various mechanisms, mainly including mitochondrial dysfunction and inflammation. Alternatively, mitochondrial dysfunction plays a central role. The I/R injury may cause cells’ injury and even death. However, the mechanism of I/R injury and the way of cell damage or death are still unclear. We review the pathophysiology of I/R injury, which is majorly about mitochondrial dysfunction. Then, we focus on the cell damage and death during I/R injury. Further comprehension of the progress of I/R will help identify biomarkers for diagnosis and therapeutic targets to PAD. In addition, traditional Chinese medicine has played an important role in the treatment of I/R injury, and we will make a brief introduction.

scholarly journals Treating Ulcerative Colitis by Activating Blood Circulation to Dissipate Blood Stasis

2021 ◽  
Vol 5 (5) ◽  
pp. 37-39
Author(s):  
Yi Hu ◽  
Tao Yu
Keyword(s):  
Colorectal Cancer ◽  
Ulcerative Colitis ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Bowel Disease ◽  
Blood Circulation ◽  
Blood Stasis ◽  
New Ideas ◽  
The Relationship ◽  
Over Time

Ulcerative colitis (UC) is a worldwide refractory bowel disease with unclear pathogenesis. Its lesions can lead to colorectal cancer over time. UC is classified as “diarrhea,” “dysentery,” and other categories in traditional Chinese medicine. Its etiology and pathogenesis in traditional Chinese medicine are complex, but it has been found that blood stasis plays an important role in its occurrence and development. Combined with modern research, the relationship between blood stasis and ulcerative colitis is analyzed in this article along with a discussion on the therapeutic effect of activating blood and removing blood stasis on the disease, aiming to provide new ideas for the treatment of UC.

Science communication activism: Protesting Traditional Chinese Medicine in China

2019 ◽  
Vol 28 (7) ◽  
pp. 812-827
Author(s):  
Qiaoyan Zhu ◽  
Maja Horst
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Science Communication ◽  
Participant Observation ◽  
Observation Study ◽  
Western Countries ◽  
The Relationship

This article investigates how activists use science communication to protest the regulation and use of Traditional Chinese Medicine in China. The article reports on a participant observation study of the motivations of the activists as well as the form and content of their activities. The article hereby questions the apparently close links between the systems of state and science in China. It also points to different configurations of the relationship between scientists, activists, science communication and publics than what has been common in analyses of science communication and activism in Western countries.

Ethnobotany

2022 ◽  
pp. 270-291
Author(s):  
Akash ◽  
Navneet ◽  
Bhupendra Singh Bhandari ◽  
Surendra Singh Bisht ◽  
Dalip Kumar Mansotra
Keyword(s):  
Natural Products ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Traditional Medicine ◽  
Recent Time ◽  
Ethnomedicinal Plants ◽  
Traditional Medicines ◽  
Relationship Of ◽  
The Relationship

Traditional medicines and natural products from ethnomedicinal plants have great significance in recent time. Various forms of medicines like Ayurveda, traditional Chinese medicine, kampo, Unani, have been plasticising in recent days due to their effectiveness against various human ailments and also have blossomed into the regulated systems of traditional medicine. This chapter reviews the relationship of plants and humans, along with their cultural relationship and role of the traditional medicines, by exploring the methodologies and various concepts for the discovery of various drugs. Further, this will also illustrate traditional medicines that have their incomparable advantages over the modern allopathic medicines.

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