scholarly journals Acute Nonatherosclerotic Coronary Thromboembolism Presenting with an Inferior STEMI in a Patient on Oral Contraception

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Nabil Braiteh ◽  
Raheel Chaudhry ◽  
Ibraheem Rehman ◽  
Jowana Breiteh ◽  
Alon Yarkoni
Keyword(s):  
Acute Coronary Syndrome ◽  
Oral Contraceptive ◽  
Oral Contraceptive Pill ◽  
Anticoagulation Therapy ◽  
Cardiac Risk ◽  
Troponin Elevation ◽  
Oral Contraceptive Pills ◽  
Coronary Syndrome ◽  
Contraceptive Pills ◽  
Coronary Embolism

Background. Direct coronary embolism in the setting of oral contraceptive pill (OCP) use is a rare adverse effect. It is known for OCP to increase the risk of thrombosis; however, leading to an inferior ST elevated myocardial infarction (STEMI) due to an acute occlusive embolism is a rare entity. Coronary embolism occurs in about 3% of patients with acute coronary syndrome. Case Report. We present a case of a young 41-year-old female with a past medical history significant for dysfunctional uterine bleeding on oral contraceptive pills, who presented to the hospital with chest pain. Her workup was significant for troponin elevation and an electrocardiogram showing inferior ST elevations. The patient was taken emergently to the cardiac catheterization lab. A coronary angiogram revealed a coronary thrombus involving the distal left main and proximal left anterior descending (LAD) with no evidence of atherosclerotic disease. The patient subsequently received anticoagulation therapy leading to complete resolution of symptoms and ST elevations. Conclusion. Coronary embolism is rare and often not considered in the differential of acute coronary syndrome. It is of utmost importance for clinicians to keep a wide differential of nonatherosclerotic causes of STEMI especially when the patient is young, without significant cardiac risk factors.

scholarly journals The Effect of Oral Contraceptive Pills on The Gene Mutation of Factor V Leiden among Sudanese Women

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Kawthar Abdelgaleil Mohammed Salih ◽  
Hiba Abdelmalik ◽  
Hiba Babiker ◽  
Ahmed Bakheet Abd Alla
Keyword(s):  
Oral Contraceptive ◽  
Gene Mutation ◽  
Oral Contraceptive Pill ◽  
Factor V Leiden ◽  
Factor V ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pill ◽  
Contraceptive Pills ◽  
Significant Difference ◽  
The Impact

Oral contraceptive pills are problems for women, often have many effects, and may cause several diseases. The purpose of this research was to determine the impact of oral contraceptive pills on factor V sufferers. This case-control study conducted in Khartoum Sudan during the period from April to November 2018. The study included 50 women who used oral contraceptive as a case and 50 women who did not use oral contraceptive pills as a control, all of whom were verbally informed of the study and approved for participation. The PCR do for each sample. The results obtained from cases show that the mean age is 30±5.5 and divided into three groups less than 20 with a lower frequency of 4 % (2/50), (20-35) with a higher incidence of 80 % (40/50) and a higher rate of 16 % (8/50) for more than 35 years. Most cases use the oral contraceptive pill for more than one year at a frequency of 60% (30/50) with a mean of 2±0.8. The most frequent oral contraceptive pill use was levonorgestrel 88% (44/50), followed by desogestrel 12% (6/50). The study concludes that there is no significant difference in gene mutation between case and control. There was also an insignificant association between the mutation and demographic data.

Chest pain

2015 ◽  
Author(s):  
Hugo Farne ◽  
Edward Norris-Cervetto ◽  
James Warbrick-Smith
Keyword(s):  
Acute Coronary Syndrome ◽  
Oral Contraceptive ◽  
Chest Pain ◽  
Aortic Dissection ◽  
Older People ◽  
Oral Contraceptive Pill ◽  
Contraceptive Pill ◽  
Coronary Syndrome ◽  
Combined Oral Contraceptive ◽  
History Of

A good way to come up with a list of causes is to visualize the anatomy of the affected area and think of what could go wrong. Thus, in chest pain, there may be pathology of the heart, aorta, lungs, pulmonary vessels, oesophagus, stomach, thoracic nerves, thoracic muscles, or ribs. The main causes of acute chest pain in an individual aged over 60 include are listed in Figure 9.1. A younger patient is less likely to be suffering from diseases of old age, such as: • Acute coronary syndrome • Stable angina • Myopericarditis (usually post-infarction) • Thoracic aortic dissection • Thoracic aortic aneurysm A younger female patient on the combined oral contraceptive pill is more likely to be suffering from: • PE (the combined oral contraceptive pill is thrombogenic) • Pneumothorax (especially if tall and thin) • Cocaine-induced coronary spasm (still rare, but particularly unusual in older people). The following diagnoses require immediate management and should be kept in mind: • Acute coronary syndrome (unstable angina, or myocardial infarction (MI)) • Aortic dissection • Pneumothorax • PE • Boerhaave’s perforation The key features of each are listed below. 1 Features of acute coronary syndrome ■ History of sudden-onset, central, crushing chest pain radiating to either/both arms, neck or jaw, usually lasting a few minutes to half an hour (longer if there is ongoing infarction). Have a higher index of suspicion in those with a previous history of angina on exertion or MI and/or cardiovascular risk factors (smoking, hypertension, hypercholesterolaemia, diabetes mellitus, family history). ■ Signs of hypercholesterolaemia: cholesterol deposits in small skin lumps on the back of the hand or bony prominences like elbows (xanthomata), in creamy spots around the eyelids (xanthelasma), or a creamy ring around the cornea (arcus). Note that arcus is a normal finding in older people. ■ Signs of peripheral (atherosclerotic) vascular disease: weak pulses, peripheral cyanosis, cool peripheries, atrophic skin, ulcers, bruits on auscultation of carotids. ■ Signs of brady- or tachyarrhythmia. An arrhythmia is relevant for two reasons.

scholarly journals Status of Serum Iron and Copper in Women Taking Oral Contraceptive

2018 ◽  
Vol 10 (1) ◽  
pp. 5-9
Author(s):  
F Hasanat ◽  
PK Chakroborty ◽  
A Hasanat ◽  
SK Sharmin ◽  
MB Mannan ◽  
...  
Keyword(s):  
Oral Contraceptive ◽  
Serum Iron ◽  
Oral Contraceptive Pill ◽  
Copper Level ◽  
Oral Contraceptive User ◽  
Oral Contraceptive Pills ◽  
Contraceptive User ◽  
Contraceptive Pills ◽  
The Status ◽  
Human Need

The oral contraceptive pill fulfills the great human need for birth control with unrivalled effectiveness. The pill can effectively prevent pregnancy and alleviate many menstrual disorders when used correctly. Many biochemical profiles of women taking oral contraceptives are disturbed due to metabolic alterations induced by its hormone content. The study was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh, during the period of July 2016 to June 2017 to evaluate the status of serum iron and copper in women taking oral contraceptive pills. For this study 120 agematched women were selected and grouped as 60 oral contraceptive user women and 60 non-oral contraceptive user women. Data were analyzed with the help of SPSS version 21. Mean(±SD) level of serum iron and copper were 155.20±21.94 mg/dl and 157.6±14.75 mg/dl in oral contraceptive user women, while in normal healthy women the levels were 103±19.11 mg/dl and 126.28±17.18 mg/dl respectively. Serum iron and copper levels were significantly increased in oral contraceptive user group when compared with that of normal healthy group (p<0.001). From this study it can be concluded that there is significant association of serum iron and copper level with oral contraceptives.Bangladesh J Med Biochem 2017; 10(1): 5-9

scholarly journals Cerebral Vein and Sinus Thrombosis in Isfahan-Iran: A Changing Profile

2004 ◽  
Vol 31 (4) ◽  
pp. 474-477 ◽  
Author(s):  
Mohammad Saadatnia ◽  
Seyyed Ali Mousavi ◽  
Sassan Haghighi ◽  
Ashraf Aminorroaya
Keyword(s):  
Oral Contraceptive ◽  
Sinus Thrombosis ◽  
Tertiary Care ◽  
Oral Contraceptive Pill ◽  
Predisposing Factors ◽  
Diagnostic Tools ◽  
Cerebral Vein ◽  
Care Hospital ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills

Objectives:This study was performed to investigate the clinical presentation and predisposing factors for cerebral vein and sinus thrombosis (CVST) in Isfahan, Iran.Methods:Data from the records of all patients with CVSTreferred to the largest tertiary-care hospital of Isfahan during a five-year period (1997 to 2001) were extracted and reviewed.Results:The number of cases with CVST diagnosed annually was 6, 9, 11, 14 and 15 patients, respectively. Thirteen men and 42 women were diagnosed to have CVST with the mean age of 35.1± 3.8 and 28.7±1.3 years, respectively. Headache was the most frequent complaint (95%) and 63% of patients had focal neurological symptoms, including seizure (58%). Among possible predisposing factors, oral contraceptive pill was the most prevalent one, which was used by 38.1% of affected women for a period of as short as 1-3 months. Anticardiolipin antibodies were detected in 14% of patients.Conclusion:It seems that the annual incidence of CVST is increasing in Isfahan, perhaps due to more extensive intake of oral contraceptive pills and usage of more accurate modern diagnostic tools. The use of oral contraceptive pills was the most frequent predisposing factor; infections and postpartum factors were infrequently observed. Despite other reports from the Middle East, Behçet's disease is not a principal risk factor for CVST in Isfahani patients.

scholarly journals Acceptability, side-effects and discontinuation of second and third-generation oral contraceptive pills in Bangladesh: A quasi-experimental study

2020 ◽  
Author(s):  
Mahbub Elahi Chowdhury ◽  
Andrea Youta Wamen ◽  
Shafayatul Islam Shiblee ◽  
Md. Mahbub Ul Alam ◽  
Md Niajur Rahman ◽  
...  
Keyword(s):  
Experimental Study ◽  
Oral Contraceptive ◽  
Side Effects ◽  
Health Workers ◽  
Oral Contraceptive Pill ◽  
Control Group ◽  
Third Generation ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Quasi Experimental

Abstract Background The third-generation oral contraceptive pill (3G-OCP) has improved side-effect profile compared to the second-generation (2G-OCP). In Bangladesh, comparative data on these two generations of OCPs is nonexistent. This study aimed to compare acceptability, side-effects and discontinuation rates between 3G- and 2G-OCPs. Methods This quasi-experimental study was conducted from October 2017 to June 2018 in two unions of one sub-district in Bangladesh. From each intervention and control unions, 1400 women were enrolled after screening for selection criteria. All the women in the intervention union received 3G-OCP while those in the control union had 2G-OCP. Women from both the groups were provided six cycles of OCPs, two at enrollment, and two each at two subsequent home-visits at 2-months apart by the health workers. Data was collected thrice: immediately after enrolment, and two subsequent follow-up visits at 2-months interval by the study interviewers. Life table analysis was done to compare cumulative discontinuation rates and Hazard Ratio (HR) was estimated for likelihood of discontinuation of 3G-OCP as compared to 2G-OCP due to side-effects. Results After 24-weeks of enrollment, 69.1% (n=967) of the women from the intervention and 58.0% (n=812) from the control group continued with the method. The major reason for discontinuation was pill use-related side-effects (3G-OCP: 20.4% vs. 2G-OCP: 19.5%). Initially, the reported side-effects for 3G-OCP were higher than those for 2G-OCP (47.3% vs. 33.2%). However, after 24-weeks of use, the corresponding figures became similar (9.5% vs. 8.7%). The cumulative discontinuation rate due to side-effects was 22.8% and 25.2% for 3G- and 2G-OCP respectively which was not statistically significant (p=0.14). After adjusting for potential covariates, the likelihood of discontinuation of 3G-OCP was 14% lower (HR=0.86, p=0.075) than 2G-OCP which was statically significant at 10% level. The study observed three deaths (one in intervention and two in control), of which one death in the control group was due to stroke. Conclusion The 3G-OCP was less likely to be discontinued than the 2G-OCP due to side effects. After 24-weeks of use the reported side-effects of the two types of OCPs was similar. However, one stroke-related-mortality due to use of 2G-OCP, demanded further larger studies.

scholarly journals Knowledge, Attitude and Practice of Women in Jeddah Towards the Use of Oral Contraceptive Pills

2017 ◽  
Vol 7 (2) ◽  
pp. 5-10
Author(s):  
Hanan M. Shamrani ◽  
Arwa F. Shamrani ◽  
Abdulrahman E. Alsaggaf ◽  
Mohammad I. Khojah ◽  
Maram M. Alafif ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Oral Contraceptive ◽  
Oral Contraceptive Pill ◽  
P Value ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pill ◽  
Jeddah City ◽  
Attitude And Practice ◽  
Contraceptive Pills ◽  
Knowledge Attitude And Practice

Objective (Background): The use of oral contraceptive pill is considered an acceptable practice worldwide. Socio-demographic patterns in Saudi Arabia are rapidly changing with time. This study aims to evaluate the knowledge, attitude and practice among women in Jeddah towards the use of oral contraceptive pills. Methodology: A cross-sectional study was conducted using a self-administered questionnaire as a tool for data collection. Results: The study was conducted in Jeddah city in the Western region of Saudi Arabia between 2014-2015, 913 women were approached and 40 refused to participate (4.378% refusal rate). Out of those 873 who agreed to participate, 713 responded correctly and were included (78.09% response rate). Participants were grouped into six categories based on their age. The majority of the women polled were Saudis (71.4%). There was a positive correlation between the attitude of women towards the use of oral contraceptive pill and age (P-value < 0.001). Similar correlation was true also in the case of knowledge and the level of education towards the use of oral contraceptive pills. There was a significant correlation between marital status towards oral contraceptive pill use (P-value <0.001). Conclusions: This study should be extended to other regions of the kingdom. The results emphasize the need for women in Jeddah city as well as the rest of Saudi Arabia to be better educated, aware and informed about the different contraceptive methods available in order for them to make the right decision regarding the method they like to choose for birth control.

The Association between Current Low-Dose Oral Contraceptive Pills and Periodontal Health: A Matched-Case-Control Study

2010 ◽  
Vol 11 (3) ◽  
pp. 33-40 ◽  
Author(s):  
Amir Moeintaghavi ◽  
Ahmad Haerian-ardakani ◽  
Mahammadreza Reza Talebi-Ardakani ◽  
Keyvan Sohrabi ◽  
Shahin Bahmani ◽  
...  
Keyword(s):  
Oral Contraceptive ◽  
Birth Control ◽  
Oral Contraceptives ◽  
Oral Contraceptive Pill ◽  
Plaque Index ◽  
Periodontal Health ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pill ◽  
Young Females ◽  
Contraceptive Pills

Abstract Aim This study assessed the influence of current oral contraceptive pills on periodontal health in young females. Methods and Materials Seventy women ranging in age from 17 to 35 years (mean 24 years) had a comprehensive periodontal examination. Their current and previous oral contraceptive pill use was assessed by a questionnaire. A periodontal assessment was performed that included recording the following: plaque index, gingival index, probing depth, and attachment level at six sites per tooth. The periodontal health of women taking birth control pills for at least two years was compared to that of women not taking an oral contraceptive. The control and test groups were matched for socioeconomic status, age, oral habits, occupation, and educational levels. Results Although there was no difference in plaque index levels between the two groups, current oral contraceptive pill users had higher levels of gingival inflammation and bleeding on probing. However, no significant differences were found regarding mean probing depths and attachment loss between the two groups. Conclusion Women who were on oral contraceptive pills had more extensive gingivitis and gingival bleeding than their matched controls not taking them. Clinical Significance As birth control policies are advocated by most countries, and because oral contraceptives are the most widely used method for birth control, a need exists to assess the effects of oral contraceptives on the periodontal health of young women. Although additional studies are needed to better understand the mechanism of OC-induced gingivitis, female patients should be informed of the oral and periodontal side effects of OCs and the need for meticulous home care and compliance with periodontal maintenance.

Study the Relationship Between Estrogen Hormone and Calcium in Normal Females Before and After Menopause in Baghdad / Iraq

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan
Keyword(s):  
Oral Contraceptive ◽  
Healthy Controls ◽  
Serum Samples ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Menopausal Women ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Age Range

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.

Effect of short-term use of oral contraceptive pills on intraocular pressure

2020 ◽  
Vol 35 (3) ◽  
Author(s):  
Tayyaba Gul Malik ◽  
Hina Nadeem ◽  
Eiman Ayesha ◽  
Rabail Alam
Keyword(s):  
Oral Contraceptive ◽  
Childbearing Age ◽  
Short Term ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Time Period ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Short Time

Objective: To study the effect of short-term use of oral contraceptive pills on intra-ocular pressures of women of childbearing age.   Methods: It was a comparative observational study, conducted at Arif memorial teaching hospital and Allied hospital Faisalabad for a period of six months. Hundred female subjects were divided into two groups of 50 each. Group A, included females, who had been taking oral contraceptive pills (OCP) for more than 6 months and less than 36 months. Group B, included 50 age-matched controls, who had never used OCP. Ophthalmic and systemic history was taken. Careful Slit lamp examination was performed and intraocular pressures (IOP) were measured using Goldman Applanation tonometer. Fundus examination was done to rule out any posterior segment disease. After collection of data, we analyzed and compared the intra ocular pressures between the two groups by using ANOVA in SPSS version 21.   Results: Average duration of using OCP was 14.9 months. There was no significant difference of Cup to Disc ratios between the two groups (p= 0.109). However, significant difference was noted between the IOP of OCP group and controls. (p=0.000). Conclusion: OCP significantly increase IOP even when used for short time period.

Sign in / Sign up

Export Citation Format

Share Document