scholarly journals Oral Dextrose Gel Reduces the Need for Intravenous Dextrose Therapy in Neonatal Hypoglycemia

2016 ◽  
Vol 1 (3) ◽  
pp. 1-9 ◽  
Author(s):  
Munmun Rawat ◽  
Praveen Chandrasekharan ◽  
Stephen Turkovich ◽  
Nancy Barclay ◽  
Katherine Perry ◽  
...  

Background: Newborn infants with risk factors may require intravenous (IV) dextrose for asymptomatic hypoglycemia. Administration of IV dextrose and transfer to the neonatal intensive care unit (NICU) may interfere with parent-infant bonding. Objective: To study the effect of implementing dextrose gel supplement with feeds in late preterm/term infants affected by asymptomatic hypoglycemia on reducing IV dextrose therapy. Method: A retrospective study was conducted before and after dextrose gel use: 05/01/2014 to 10/31/2014 and 11/01/2014 to 04/30/2015, respectively. Asymptomatic hypoglycemic (blood glucose level <45 mg/dl) infants in the newborn nursery (NBN) were given a maximum of 3 doses of dextrose gel (200 mg/kg of 40% dextrose) along with feeds. Transfer to the NICU for IV dextrose was considered treatment failure. Results: Dextrose gel with feeds increased the blood glucose level in 184/250 (74%) of asymptomatic hypoglycemic infants compared to 144/248 (58%) with feeds only (p < 0.01). Transfer from the NBN to the NICU for IV dextrose decreased from 35/1,000 to 25/1,000 live births (p < 0.01). Exclusive breastfeeding improved from 19 to 28% (p = 0.03). Conclusions: Use of dextrose gel with feeds reduced the need for IV fluids, avoided separation from the mother and promoted breastfeeding. Neonates who failed dextrose gel therapy were more likely to be large for gestational age, delivered by cesarean section and had lower baseline blood glucose levels.

Author(s):  
Hugo Eduardo de Amorim ◽  
Gilmar Moraes Santos ◽  
Luis Mochizuki ◽  
Evangelos Pappas ◽  
Vanessa Lima Silva ◽  
...  

Abstract Despite the increase in the number of Ironman competitions worldwide, thousands of athletes have been joining Ironman experience but only a few studies have been published on the effects of this competition on postural control. This study aims to investigate the ability to maintain a static posture in three different positions before and after an Ironman competition and the blood glucose level behavior. Forty-nine volunteers underwent balance evaluation using the force plate VSRTM Sport. The area of the center of gravity (ACOG) was assessed pre- and post-competition in the bipodal, unipodal, and tandem postures. Glucose levels were also assessed concurrently. The ACOG findings showed a significant post-competition increase in the three postures assessed, with no significant interaction between the postures. The glucose test showed an increase in the post-competition glycemic levels. The findings showed reduced postural control, suggesting that prolonged exercise stimulation could lead to a disturbance in postural control.


2019 ◽  
Vol 7 (16) ◽  
pp. 2607-2611 ◽  
Author(s):  
Dahlia Rosally Turangan ◽  
Bahagia Loebis ◽  
Surya M. Husada ◽  
Nazli Mahdinasari Nasution

BACKGROUND: Schizophrenia is a serious disorder of the brain and mind. People with schizophrenia are at high risk of developing type diabetes, due to overall poor physical health, poor health care, unhealthy lifestyles, and side effects of antipsychotic drugs. However, atypical antipsychotics have their deficiencies, because they can be associated with worsening cardiovascular risk factors such as weight gain, hyperglycemia and hyperlipidemia. AIM: Difference in fasting blood glucose levels in people with schizophrenia between before and after receiving aripiprazole treatment. METHODS: This research was conducted in November 2017-September 2018. This research was first conducted in Indonesia, especially North Sumatra. This research is a numerical comparative analytical study paired with an experimental design approach. The number of samples is 44 people. Blood samples are taken in schizophrenia patients before getting the drug, before meals and before activities, assessed fasting blood glucose levels before being treated with aripiprazole and after drug administration for 6 weeks. Data analysis used was a paired test for differences in fasting blood glucose levels in people with schizophrenia between before and after receiving aripiprazole treatment. RESULTS: Based on the demographic characteristics found the research subjects based on the most age group were 31-40 years age group of 30 subjects (68.2%), based on the highest level of education was high school by 26 subjects (59.1%), based on the most marital status was by status not married for 24 subjects (54.5%). It was found that the average blood glucose level before being given aripiprazole in schizophrenic patients was 89.23 ± 7.13. It was found that the average blood glucose level after being given aripiprazole in schizophrenic patients was 86.5 ± 10.1. It was found that there were no differences in blood glucose levels before and after being given aripiprazole in schizophrenic patients CONCLUSION: There was no difference in blood glucose levels before and after being given aripiprazole in schizophrenic patients with p-value (0.078).


2016 ◽  
Vol 10 (1) ◽  
pp. 45
Author(s):  
Alkhalidri Murfi ◽  
Zuhrawati Zuhrawati ◽  
Sugito Sugito ◽  
Rusli Rusli ◽  
Al Azhar ◽  
...  

The objective of this study was to examine glucose level in dog's blood before and after hunting activity. This research used 25 local dogs which is kept by Persatuan Olah Raga Buru Babi (PORBI) located at Kenagarian Mungo Sub-district Luak District Kabupaten Lima Puluh Kota West Sumatera. Data were analyzed with T-test. Results showed that average of dog blood glucose level before hunting was 91.56±7.70 mg/dl and significantly decrease (P<0.05) to 57.84±5.04 mg/dL after hunting activity. As a conclusion, blood glucose level of dog before hunting activity was found in normal range but lowered glucose level were observed after hunting activity.


2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Ni Putu G. A. Lande ◽  
Yanti Mewo ◽  
Michaela Paruntu

Abstract: Physical activity is one of the factors which can affect blood glucose level in human body. Vigorous physical activity for 20 minutes can lower one’s blood glucose level. Futsal is categorized as a vigorous activity. During the activity, body will use endogenous fuel from blood to take care of glucose levels homeostasis in it. This study aimed to determine the ratio of blood glucose levels before and after vigorous physical activity at the 2011 batch students of the Faculty of Medicine, University of Sam Ratulangi using futsal. This was a pre and post experimental study. Respondents were 21 males aged 20-22 years. The results showed a decrease of all respondents’ blood glucose average from104.14 mg/dL before the physical activity to 95.40 mg/dL after it with p < 0.05 that meant there was a significant decrease in glucose level. Conclusion: In this study, there was a significant difference in blood glucose levels of the students between before and after vigorous physical activity.Keywords: blood glucose levels, vigorous physical activityAbstrak: Aktivitas fisik merupakan salah satu faktor yang dapat mempengaruhi kadar glukosa darah dalam tubuh manusia. Aktivitas fisik intensitas berat yang dilakukan selama 20 menit dapat menurunkan kadar glukosa darah dalam tubuh. Futsal merupakan salah satu permainan yang tergolong dalam aktivitas intensitas berat. Selama aktivitas fisik dilakukan, tubuh akan menggunakan bahan bakar endogen dan dari darah untuk menjaga homeostasis kadar glukosa dalam tubuh. Penelitian ini bertujuan untuk mengetahui perbandingan kadar glukosa darah sebelum dan sesudah aktivitas fisik intensitas berat pada mahasiswa angkatan 2011 Fakultas Kedokteran Universitas Sam Ratulangi melalui permainan futsal. Penelitian ini bersifat pre dan post eksperimental. Pada penelitian ini responden terdiri dari 21 orang laki-laki dengan umur 20-22 tahun. Hasil penelitian menunjukkan adanya penurunan glukosa dari rata-rata 104,14 mg/dL sebelum aktivitas fisik menjadi 95,40 mg/dL setelah melakukan aktivitas fisik dengan nilai p < 0,05, yang berarti terjadi penurunan yang signifikan. Simpulan: Terdapat perbedaan yang signifikan antara kadar glukosa darah mahasiswa sebelum dan sesudah melakukan aktivitas fisik intensitas berat.Kata kunci: kadar glukosa darah, aktivitas fisik intensitas berat


2016 ◽  
Vol 3 (2) ◽  
pp. 29-34
Author(s):  
Yoga Pratama Lumban Tobing ◽  
Robiyanto ◽  
Rafika Sari

Diabetes mellitus is metabolic disorder caused by high glucose level due to abnormalities in insulin secretions, work or both that can be caused by alpha-glucosidase and alpha-amylase in intestine. Cucumbers (Cucumis sativus) and cowpeas (Vigna sinensis) are reported as anti-diabetic. The objective of the present study was to determine the effectiveness of cucumber-cowpea juice combination with single juice and metformin on lowering blood glucose level. Rats were made hyperglycemic by induced sucrose 6,825 g/Kg BW orally. Sample was taken on the lateral vein rat tail. Blood glucose levels were observed before and after juice induction in 30, 60, 90, and 120 minutes by using glucometer. The results were analyzed by Mann-Whitney methods. Single cucumber juice 14,11 g/Kg BW and combination cowpea-cucumber juice 26,4 g/Kg BW – 42 g/Kg BW were given the optimum effect. Both the optimum dose have significant level with metformin as positive control (p>0,05). Results showed that the combination have significant level on lowering blood glucose level compared with metformin.


Trials ◽  
2022 ◽  
Vol 23 (1) ◽  
Author(s):  
Tao Yuan ◽  
Hongyu He ◽  
Yuepeng Liu ◽  
Jianwei Wang ◽  
Xin Kang ◽  
...  

Abstract Background Blood glucose levels that are too high or too low after traumatic brain injury (TBI) negatively affect patient prognosis. This study aimed to demonstrate the relationship between blood glucose levels and the Glasgow Outcome Score (GOS) in TBI patients. Methods This study was based on a randomized, dual-center, open-label clinical trial. A total of 208 patients who participated in the randomized controlled trial were followed up for 5 years. Information on the disease, laboratory examination, insulin therapy, and surgery for patients with TBI was collected as candidate variables according to clinical importance. Additionally, data on 5-year and 6-month GOS were collected as primary and secondary outcomes, respectively. For multivariate analysis, a generalized additive model (GAM) was used to investigate relationships between blood glucose levels and GOS. The results are presented as odds ratios (ORs) with 95% confidence intervals (95% CIs). We further applied a two- piecewise linear regression model to examine the threshold effect of blood glucose level and GOS. Results A total of 182 patients were included in the final analysis. Multivariate GAM analysis revealed that a bell-shaped relationship existed between average blood glucose level and 5-year GOS score or 6-month GOS score. The inflection points of the average blood glucose level were 8.81 (95% CI: 7.43–9.48) mmol/L considering 5-year GOS as the outcome and were 8.88 (95% CI 7.43−9.74) mmol/L considering 6-month GOS score as the outcome. The same analysis revealed that there was also a bell relationship between average blood glucose levels and the favorable outcome group (GOS score ≥ 4) at 5 years or 6 months. Conclusion In a population of patients with traumatic brain injury, blood glucose levels were associated with the GOS. There was also a threshold effect between blood glucose levels and the GOS. A blood glucose level that is either too high or too low conveys a poor prognosis. Trial registration ClinicalTrials.gov NCT02161055. Registered on 11 June 2014.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mrs. Vanitha. S s ◽  
Dr. Pramjit kaur

Challenges in lifestyle, such as increasesin energy intake and decreasesin physical activity are causing overweight and obesity leading to epidemic increases in type II Diabetes Mellitus. The research approach used for this study was evaluative approach and the research design was true experimental design. 60 patients with type II diabetes, 30 in experimental group and 30 in control group were selected for this study by using purposive sampling technique. Data was collected with the help of self-structured interview schedule. Descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (chi-square, paired ‘t’ test) were used to analyse the data and to test the hypotheses. In the experimental group,the pre-test mean score was 2.966, mean percentage was 59% and standard deviation was 1.129 and in post-testmean score was 2.533, mean percentage was 50.66% and standard deviation was 1.074 with effectiveness of 8.34% and paired‘t’ test value of t=3.971,which was statistically significant (p<0.05) which is an evidence ofthe effectiveness of Amla juice in reducing blood glucose level. Comparison of blood glucose levels in experimental and control groups, shows that the value is statistically highly significant, as was observed from the unpaired ‘t’ test value of 13.39 with P value of <0.05, which is an evidence indicatingthe effect of Amla juice in reducing postprandial blood glucose levels. The resultsfound that the administration of Amla juice did have aneffect in reducing blood glucose level in the experimental group. By comparing the findings of pre-test and post test between the experimental group and the control group,the effect was identified (assessed). The study concluded that the Amlajuice is effective in reducing blood glucose level.


2021 ◽  
Vol 5 (1) ◽  
pp. 14-25
Author(s):  
Nurul Fadhilah ◽  
Erfiani Erfiani ◽  
Indahwati Indahwati

The calibration method is an alternative method that can be used to analyze the relationship between invasive and non-invasive blood glucose levels. Calibration modeling generally has a large dimension and contains multicolinearities because usually in functional data the number of independent variables (p) is greater than the number of observations (p>n). Both problems can be overcome using Functional Regression (FR) and Functional Principal Component Regression (FPCR). FPCR is based on Principal Component Analysis (PCA). In FPCR, the data is transformed using a polynomial basis before data reduction. This research tried to model the equations of spectral calibration of voltage value excreted by non-invasive blood glucose level monitoring devices to predict blood glucose using FR and FPCR. This study aimed to determine the best calibration model for measuring non-invasive blood glucose levels with the FR and FPCR. The results of this research showed that the FR model had a bigger coefficient determination (R2) value and lower Root Mean Square Error (RMSE) and Root Mean Square Error Prediction (RMSEP) value than the FPCR model, which was 12.9%, 5.417, and 5.727 respectively. Overall, the calibration modeling with the FR model is the best model for estimate blood glucose level compared to the FPCR model.


2021 ◽  
Vol 74 (9) ◽  
pp. 2277-2280
Author(s):  
Hanan Fawzi ◽  
Alaa Hussen Ali

The aim: To compared blood glucose concentrations after intravenous injection of dexamethasone in the pregnant and non-pregnant women under general anesthesia. Materials and methods: Eighty patients aged 18-50 years took part in the study (ASA class 1 and 2). Forty of patients were undergoing elective cesarean section under G/A and the other forty undergoing elective laparoscopic Cholecystectomy under G/A. Anesthesia was induced using IV anesthetic drugs (0.5mg/kg ketamine, sleeping dose of propofol up to 2mg/kg, muscle relaxant was 0.6 mg/kg rocuronium and maintained with isoflurane). All of patients have been injected with 0,1mg/kg dexamethasone intravenously, at induction of anesthesia, Blood glucose concentrations were measured at induction and then in 60min, 180min and in 360 min after injection of dexamethasone and results were compared between the groups; IV fluid added was normal saline (0.9%) during the study. Results: Regarding to blood glucose levels, we noticed that its level significantly increased over time and peaked in 180min after dexamethasone injection in both groups. The difference percentage between the lower reading (pre injection) and the upper reading (in 180min after) was 33.5% in pregnant woman and 46.2%for non-pregnant women, this difference was statistically significant relative to the pre injection, as this difference was lower in the pregnant women. In 360min after blood glucose level began to drop in both groups. After giving 0.1 mg/kg of dexamethasone, blood glucose level increased in both groups, but it was lower in pregnant women.


Sign in / Sign up

Export Citation Format

Share Document