scholarly journals How to Intervene in the Caries Process: Dentin Caries in Primary Teeth

2020 ◽  
Vol 54 (4) ◽  
pp. 306-323
Author(s):  
Ruth M. Santamaría ◽  
Mohamed Hassan Abudrya ◽  
Gülsün Gül ◽  
MHD Said Mourad ◽  
Grace Felix Gomez ◽  
...  

For an ORCA/EFCD consensus, this review systematically assessed available evidence regarding interventions performed and materials used to manage dentin carious lesions in primary teeth. A search for systematic reviews (SRs) and randomized clinical trials (RCTs) with a follow-up of at least 12 months after intervention was performed in PubMed, LILACS, BBO, and the Cochrane Library. The risk of bias tool from the Cochrane Collaboration and the PRISMA Statement were used for assessment of the included studies. From 101 screened articles, 2 SRs and 5 RCTs, which assessed the effectiveness of interventions in terms of pulp vitality and success of restoration, and 10 SRs and 1 RCT assessing the success of restorative materials were included. For treatments involving no carious tissue removal, the Hall technique showed lower treatment failure for approximal carious lesions compared to complete caries removal (CCR) and filling. For the treatment of deep carious lesions, techniques involving selective caries removal (SCR) showed a reduction in the incidence of pulp exposure. However, the benefit of SCR over CCR in terms of pulp symptoms or restoration success/failure was not confirmed. Regarding restorative materials, preformed metal crowns (PMCs) used to restore multisurface lesions showed the highest success rates compared to other restorative materials (amalgam, composite resin, glass ionomer cement, and compomer), and in the long term (12–48 months) these were also less likely to fail. There is limited evidence supporting the use of PMCs to restore carious lesions with single cavities. Among nonrestorative options, silver diammine fluoride was significantly more effective in arresting caries than other treatments for treating active carious lesions of different depths. Considerable heterogeneity and bias risk were observed in the included studies. Although heterogeneity observed among the studies was substantial, the trends were similar. In conclusion, less invasive caries approaches involving selective or no caries removal seem advantageous in comparison to CCR for patients presenting with vital, symptomless, carious dentin lesions in primary teeth. There is evidence in favor of PMCs for restoring multisurface carious lesions in primary molars.

2016 ◽  
Vol 17 (12) ◽  
pp. 1022-1026 ◽  
Author(s):  
Deepak Khandelwal ◽  
Shweta Nihalani ◽  
Harsh Priyank ◽  
Ankita Verma ◽  
Esha Chaudhary

ABSTRACT Introduction Beauty standards in today's modernized world scenario are formed by well-aligned and well-designed bright white teeth. One of the major reasons behind patients reporting to dental clinics is pain. Caries in the anterior primary teeth forms one of the major concerns from a restorative point of view. Very few studies are quoted in literature which stresses on the follow-up of anterior restorations in primary teeth. Hence, we evaluated and compared the efficacy of composite resin and resin-modified glass ionomer cement (RGIC) for class III restorations in primary anterior teeth. Materials and methods The present study was conducted in the pediatric dental wing and included a total of 80 patients aged 3 to 5½ years who reported with the chief complaint of carious lesions in the primary anterior teeth. Patients having minimal of a pair of similar appearing small carious lesions on the same proximal surfaces of the deciduous maxillary incisors were included for the study. All the patients were randomly divided into two groups: One in which RGIC restoration was done and other in which composite restoration was done. Cavity preparation was done and filling of the cavity with the restorative materials was carried out. Assessment of the restorations was done at 4, 8, and 12 months time following criteria given by Ryge et al. All the results were analyzed by Statistical Package for the Social Sciences (SPSS) software. Mann–Whitney test and one-way analysis of variance (ANOVA) were used to evaluate the level of significance; p value less than 0.05 was considered as significant. Results For composite and RGIC restorations, the mean score for anatomic shape was 1.21 and 1.10 respectively. While comparing the clinical parameters, nonsignificant results were obtained between composite and RGIC restorative materials at 4-, 8-, and 12-month interval. On comparing the clinical parameters for individual restorative materials at different time intervals, statistically significant results were obtained only for anatomical shape and form. Conclusion Both RGIC and composite resin restorative materials showed acceptable clinical outcomes after 12 months of follow-up in deciduous anterior teeth. In restoring class III restorations in primary anterior teeth, both the restorative materials showed similar outcome. Clinical significance How to cite this article Priyank H, Verma A, Gupta K, Chaudhary E, Khandelwal D, Nihalani S. In vitro Comparative Evaluation of Various Restorative Materials used for restoring Class III Cavities in Deciduous Anterior Teeth: A Clinical Study. J Contemp Dent Pract 2016;17(12):1022-1026.


2013 ◽  
Vol 37 (4) ◽  
pp. 345-350 ◽  
Author(s):  
S Doğan ◽  
L Durutürk ◽  
AI Orhan ◽  
I Batmaz

Objectives: To determine rates of pulpal exposure during caries removal with an excavator or a bur, to assess success rates of vital pulp therapies in both cases, to analyze pulpal bleeding as an indicator of primary teeth treatability. Study Design: Of the 352 primary mandibular molars with deep carious lesions, 141 with pulp exposed during the removal of caries were grouped according to type of instrument causing pulpal exposure and existence of bleeding at the exposure site. Teeth suitable for direct pulp capping or formocresol pulpotomy were treated and followed up for two years. Results: The difference between the rates of pulpal exposure with an excavator (52.5%) or a bur (47.5%) was insignificant. The treatment success rate of teeth with pulp exposed by an excavator (15.8%) was significantly lower than teeth with pulp exposed by a bur (48.8%), regardless of whether bleeding existed at the exposure site or not; however, when bleeding existed, this difference was insignificant (15.8% and 40.6%, respectively). Conclusions: Pulpal exposure possibility during caries removal caused by an excavator and a bur was similar, the treatment success rate was lower when the exposure was caused by an excavator, the existence of pulpal bleeding resulted in mistakes in diagnoses.


2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Farah Chouchene ◽  
Fatma Masmoudi ◽  
Ahlem Baaziz ◽  
Fethi Maatouk ◽  
Hichem Ghedira

Objective. To compare the effectiveness of topical antibiotic mixtures used in noninstrumental endodontic treatment (NIET) of primary teeth. Methods. Electronic databases including MEDLINE, the Cochrane Library, and Scopus database were searched. Randomized clinical trials evaluating the clinical and radiological outcomes of topical antibiotics used in NIET were selected. The revised Cochrane risk-of-bias tool (RoB 2.0) was used to assess the quality of the methodology of the included articles. Results. Five articles comparing the outcomes of four different drugs combination were included. Three studies conducted to evaluate the success rate of two combinations of antibacterial drugs consisting of ciprofloxacin-minocycline-metronidazole (3 Mix) in one group and ciprofloxacin-minocycline-ornidazole in the other group showed no statistically significant difference between both groups ( P > 0.05 ). The ciprofloxacin-minocycline-ornidazole group showed better results compared with the 3 Mix group. One study conducted to compare the effectiveness of 3 Mix with ciprofloxacin-tinidazole-minocycline reported no significant difference between both groups, and one study that compared 3 Mix and ciprofloxacin-metronidazole-clindamycin mixture concluded that the overall success rates of both groups were 80.96% and 76.20%, respectively, with no statistically significant difference. Conclusion. Based on the overall success rates, the ciprofloxacin-minocycline-ornidazole mixture was considered more effective than the 3 Mix which was more effective than the ciprofloxacin-tinidazole-minocycline and the ciprofloxacin-metronidazole-clindamycin groups. Clinical Relevance. Different antibiotic combinations, showing good clinical and radiographic success in treating necrotic primary teeth, can be used effectively in NIET and this technique can be considered effective for teeth with advanced root resorption and when conventional endodontic treatment is contraindicated.


2009 ◽  
Vol 33 (4) ◽  
pp. 295-298 ◽  
Author(s):  
Elise Sasso Faccin ◽  
Simone Helena Ferreira ◽  
Paulo Floriani Kramer ◽  
Thiago Machado Ardenghi ◽  
Carlos Alberto Feldens

Objective: To assess the survival of Atraumatic Restorative Treatment (ART) restorations in primary teeth performed in a dental clinical setting. Study Design: One hundred and five single-surface ART restorations placed in 56 preschool children (mean age 31 months) were included. Final-year dental students performed the restorations using standard ART procedures with hand instruments. A resin-modified glass ionomer cement (Vitremer 3M/ESPE) was used as a restorative material. Performances of the restorations were assessed directly by the ART evaluation criteria. Follow-up period ranged from 6 to 48 months. Survival estimates for restoration longevity were evaluated using the Kaplan-Meier method. Log-rank test (P≤.05) was used to compare the success rates according to demographic and clinical characteristics of the restorations at baseline (age, sex, arch and segment). Results: Mean and median estimate times of survival were 37(95%CI: 32-42) months and 38 (95% CI: 29-47) months respectively. Success rates for ART restorations were 89%, 85% and 72% in 6 to 11, 12 to 24 and 25 to 48 months of evaluation respectively. Differences in success rates among demographic and clinical characteristics were not statistically significant. Conclusion:High survivals rates of the ART restorations found in this study seem to indicate the reliability of this approach as an appropriate treatment option for primary teeth in a clinical setting.


2015 ◽  
Vol 40 (4) ◽  
pp. E167-E178 ◽  
Author(s):  
HHH Hamama ◽  
CKY Yiu ◽  
MF Burrow ◽  
NM King

SUMMARY Objectives The aim of this review was to assess the methodologies used in previously published prospective randomized clinical trials on chemomechanical caries removal and to conduct a meta-analysis to quantify the differences in the excavation time between chemomechanical and conventional caries removal methods. Methods An electronic search was performed using Scopus, PubMed, EBSCO host, and Cochrane Library databases. The following categories were excluded during the assessment process: non-English studies published before 2000, animal studies, review articles, laboratory studies, case reports, and nonrandomized or retrospective clinical trials. The methodologies of the selected clinical trials were assessed. Furthermore, the reviewed clinical trials were subjected to meta-analysis for quantifying the differences in excavation time between the chemomechanical and the conventional caries removal techniques. Results Only 19 randomized clinical trials fit the inclusion criteria of this systematic review. None of the 19 reviewed trials completely fulfilled Delphi's ideal criteria for quality assessment of randomized clinical trials. The meta-analysis results revealed that the shortest mean excavation time was recorded for rotary caries excavation (2.99±0.001 minutes), followed by the enzyme-based chemomechanical caries removal method (6.36±0.08 minutes) and the the hand excavation method (atraumatic restorative technique; 6.98±0.17 minutes). The longest caries excavation time was recorded for the sodium hypochlorite-based chemomechanical caries removal method (8.12±0.02 minutes). Conclusions It was found that none of the current reviewed trials fulfilled all the ideal requirements of clinical trials. Furthermore, the current scientific evidence shows that the sodium hypochlorite-based (Carisolv) chemomechanical caries removal method was more time consuming when compared to the enzyme-based (Papacarie) chemomechanical and the conventional caries removal methods. Further prospective randomized controlled clinical trials evaluating the long-term follow-up of papain-treated permanent teeth are needed.


2018 ◽  
Vol 43 (3) ◽  
pp. E129-E151 ◽  
Author(s):  
A Reis ◽  
JL de Geus ◽  
L Wambier ◽  
M Schroeder ◽  
AD Loguercio

SUMMARY The literature was reviewed to evaluate the compliance of randomized clinical trials (RCTs) with the CONsolidated Standards of Reporting Trials (CONSORT ) and the risk of bias of these studies through the Cochrane Collaboration risk of bias tool (CCRT). RCTs were searched at Cochrane Library, PubMed, and other electronic databases to find studies about adhesive systems for cervical lesions. The compliance of the articles with CONSORT was evaluated using the following scale: 0 = no description, 1 = poor description, and 2 = adequate description. Descriptive analyses about the number of studies by journal, follow-up period, country, and quality assessments were performed with CCRT for assessing risk of bias in RCTs. One hundred thirty-eight RCTs were left for assessment. More than 30% of the studies received scores of 0 or 1. Flow chart, effect size, allocation concealment, and sample size were more critical items, with 80% receiving a score of 0. The overall CONSORT score for the included studies was 15.0 ± 4.8 points, which represents 46.9% of the maximum CONSORT score. A significant difference among countries was observed (p<0.001), as well as range of year (p<0.001). Only 4.3% of the studies were judged as at low risk; 36.2% were classified as having unclear risk and 59.4% as having high risk of bias. The adherence of RCTs evaluating adhesive systems to the CONSORT is low with unclear/high risk of bias.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 395-395
Author(s):  
Dawon Baik ◽  
Jiyoun Song ◽  
Aluem Tark ◽  
Heather Coats ◽  
Catherine Jankowski

Abstract More than 17 million family caregivers (FCGs) provide care for older adults with chronic illness in the US. Caregiving for older adults with chronic disease places a considerable burden on FCGs and they tend to neglect their personal health. Generally, physical activity (PA) programs benefit the physical and psychological health of FCGs. However, no review of PA randomized clinical trials (RCTs) focused on FCGs of older adults with chronic disease. In this systematic review, we analyzed the most recent trends (2010-2020) in RCTs identifying the effects of PA in this population. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Electronic databases (PubMed, CINAHL, Embase, PsycInfo, Cochrane Library) were searched for publications dated from 2010 to 2020. All studies included were appraised for quality using the Cochrane Collaboration Risk of Bias Tool. Of the resulting 16 studies, most studies (n=11) targeted FCGs of older adults with dementia or cancer. Most FCGs were non-Hispanic white. PA interventions with mixed modes (e.g., aerobic and resistance exercise), mixed delivery methods (e.g., in-person and telephone) and mixed settings (e.g., supervised gym- and unsupervised home sessions) were used most frequently. PA interventions significantly improved psychological health but had inconsistent effects on physical health. Tailored PA programs, designed based on FCGs’ goals, preferences and limitations, may improve upon physical health outcomes. Future PA studies should include samples of racially and ethnically diverse FCGs of older adults representing a broader range of chronic diseases.


2020 ◽  
Vol 30 (4) ◽  
pp. 392-404
Author(s):  
Elody Aïem ◽  
Clara Joseph ◽  
Anaïs Garcia ◽  
Violaine Smaïl‐Faugeron ◽  
Michèle Muller‐Bolla

Author(s):  
Ruby Rahman ◽  
Divya Reddy ◽  
Santhosh T Paul

Background: Many changes have occurred in development and availability of dental restorative materials for primary teeth. To date, there has been no emphasis to identify the approaches and materials used by pediatric dentists for primary teeth. The present study was conducted to assess the preferred choice of restorative materials among pediatric dentists for restoring primary teeth in children. Methodology: A self-administered questionnaire was utilized to obtain demographic information. Six hypothetical clinical scenarios were presented and clinicians choice of material for each of these scenario was evaluated. Statistical Analysis: Statistical analysis was done based on chi-square test. Results were displayed as percentages. Results: A total of 62 pediatric dentists completed the questionnaire, of which 97% preferred tooth-coloured materials over amalgam. Respondents reported the most influencing factors in the choice of restorative materials as age, behaviour of child and caries experience. Conclusion: Responses to various hypothetical clinical scenarios showed preference of tooth coloured materials and uniform choice of materials was noted among pediatric dentists irrespective of age or years of clinical experience. Keywords: restorative materials, primary teeth, pediatric dentists


Author(s):  
Edson Meneses da Silva Filho ◽  
Jéssica Andrade de Albuquerque ◽  
Roberta de Oliveira Cacho ◽  
Rodrigo Pegado de Abreu Freitas

Background: Diabetes mellitus is a chronic disease that is rising in many parts of the world causing damage to functionality, quality of life and public health system. Objective: Verify the effects of physical exercise on beta cells of the pancreas in diabetic subjects. Methods: The database Cochrane Library via Wiley – CENTRAL, Pubmed, LILACS, SCIELO, Web of Science, Scopus, CINAHL were used to search the articles. The descriptors and synonyms of this topic were used in the search strategy. Controlled randomized clinical trials and quasi-randomized studies, which included in their samples diabetic humans undergone any type of physical exercise were included. The Cochrane collaboration bias risk tool was used to assess the risk of bias. Results: A total of 3.133 articles were initially identified and after reading the titles/abstracts and the full text 6 articles were selected for the qualitative evaluation. Most of the studies showed positive results of physical exercise on pancreatic beta cells, insulin secretion, insulin resistance and insulin sensitivity. The main limitations were the number of studies, few, and their methodological qualities. Conclusions: Physical exercises have beneficial effects on pancreatic beta cells, insulin resistance and insulin sensitivity; however better studies designs, with fewer biases and larger samples are needed so that the results presented do not be overestimated. This review is recorded in the Prospective Register of Systematic Reviews with registration number 42017054213


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