scholarly journals Robustness of In-Laboratory and Daily-Life Gait Speed Measures over One Year in High Functioning 61- to 70-Year-Old Adults

Gerontology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Anna G.M. Rojer ◽  
Alice Coni ◽  
Sabato Mellone ◽  
Jeanine M. Van Ancum ◽  
Beatrix Vereijken ◽  
...  

Introduction: Gait speed is a simple and safe measure with strong predictive value for negative health outcomes in clinical practice, yet in-laboratory gait speed seems not representative for daily-life gait speed. This study aimed to investigate the interrelation between and robustness of in-laboratory and daily-life gait speed measures over 12 months in 61- to 70-year-old adults. Methods: Gait speed was assessed in laboratory through standardized stopwatch tests and in daily life by 7 days of trunk accelerometry in the PreventIT cohort, at baseline, and after 6 and 12 months. The interrelation was investigated using Pearson’s correlations between gait speed measures at each time point. For robustness, changes over time and variance components were assessed by ANOVA and measurement agreement over time by Bland-Altman analyses. Results: Included were 189 participants (median age 67 years [interquartile range: 64–68], 52.2% females). In-laboratory and daily-life gait speed measures showed low correlations (Pearson’s r = 0.045–0.455) at each time point. Moreover, both in-laboratory and daily-life gait speed measures appeared robust over time, with comparable and smaller within-subject than between-subject variance (range 0.001–0.095 m/s and 0.032–0.397 m/s, respectively) and minimal differences between measurements over time (Bland-Altman) with wide limits of agreement (standard deviation of mean difference range: 0.12–0.34 m/s). Discussion/Conclusion: In-laboratory and daily-life gait speed measures show robust assessments of gait speed over 12 months and are distinct constructs in this population of high-functioning adults. This suggests that (a combination of) both measures may have added value in predicting health outcomes.

2018 ◽  
Vol 127 (3) ◽  
pp. 171-177 ◽  
Author(s):  
Young Min Park ◽  
Kyung Ho Oh ◽  
Jae-Gu Cho ◽  
Seung-Kuk Baek ◽  
Soon-Young Kwon ◽  
...  

Objective: We analyzed the changes in voice- and swallowing-related symptoms that occurred over time in patients who underwent thyroidectomy and identified any associated risk factors. Methods: One hundred and three patients who underwent thyroidectomy were enrolled. Results: The mean thyroidectomy voice-related questionnaire (TVQ) score before surgery was 12.41 ± 12.19; it significantly increased to 28.24 ± 18.01 ( P < .001) 1 month postoperatively, decreased to 24.02 ± 17.30 ( P = .014) and 20.66 ± 15.29 ( P = .023) 3 and 6 months postoperatively, respectively. It was continuously decreased to 18.83 ± 14.63 twelve months postoperatively. The temporal changes in TVQ scores between patients who underwent total thyroidectomy or lobectomy were significantly different. There was a statistically significant difference in the temporal changes in TVQ according to whether neck dissection was performed. The temporal changes in TVQ in patients with and without extrathyroidal extension were significantly different. Conclusions: Voice- and swallowing-related discomfort in patients who received thyroidectomy showed dynamic changes over time. There was a significant difference in the degree of change according to clinicopathological factors. Patients with these risk factors may benefit from appropriate patient education and various rehabilitation programs for symptom relief.


2021 ◽  
Vol 5 (4) ◽  
pp. 604-622
Author(s):  
Yanhong Feng ◽  
◽  
Shuanglian Chen ◽  
Wang Xuan ◽  
Tan Yong ◽  
...  

<abstract> <p>In recent years, the frequency adjustment of U.S. monetary policy has a dynamic and global impact on other countries' economy. Based on the financial conditions index (FCI), the paper employs the time-varying parameter vector autoregressive model with stochastic volatility (TVP-VAR-SV) and spillover index respectively to investigate the time-varying impact of U.S. financial conditions (UFCI) on China's inflation (CINF) and its impact mechanisms. Some results are achieved as follows: first, the impacts of UFCI on CINF vary greatly over time both in the dimension of action duration and time point. Second, the effects of UFCI on CINF directly relate to different types of major events, and they are heterogeneous in action duration, degree, direction as well as the trend and range of fluctuations. In addition, UFCI can work on CINF through trade flow and China's financial market, and the China's financial market plays a main conductive role, and its conductive effect changes over time.</p> </abstract>


2011 ◽  
Vol 9 (2) ◽  
pp. 19-28
Author(s):  
Timothy J. Riney

At two different times, Time 1 and Time 2, 13 participants in Japan (8 Japanese and 5 Americans) were asked to spontaneously respond in English to this prompt: “Tell me about one of the most exciting or dangerous moments in your life.” The Japanese responded during their first and fourth years of college, which involved an interval of 42 months. The Americans were native speakers of English and responded earlier and later in their one year study abroad program in Japanese language and culture. Three questions addressed by this paper were the following: (a) What types of topics and narrative structures characterize these 26 stories? (b) What types of speaker-initiated repairs appear, and are the repairs the same or different at Time 1 and Time 2? (c) How are the repairs related to different listener (American, Japanese, Filipino, and Taiwanese) assessments of the intelligibility of the narratives?


2004 ◽  
Vol 3 (1) ◽  
pp. 1-15 ◽  
Author(s):  
Victor De Gruttola ◽  
Andrea S Foulkes

Markov models provide a natural framework for modeling cellular and molecular level changes over time. Kalbfleisch and Lawless propose using a Chi-squared statistic for assessing the appropriateness of assuming a first-order, homogeneous Markov process. While this statistic provides a global test of the Markov assumption, it does not permit identification of individual departures. We consider two approaches for discovering specific departures from the Markov assumption. First, we propose a diagnostic that tests whether the number of observed transitions out of a given state at a given time point is different than expected. Second, we construct statistics based on the number of observations in each state at each time point. In both cases, we construct multiple correlated statistics and testing is achieved through simulations. These approaches are applied to HIV genetics sequences measured over time.


2019 ◽  
Vol 3 (3-4) ◽  
pp. 80-96 ◽  
Author(s):  
Ashley Liggins ◽  
Jerry H. Ratcliffe ◽  
Matthew Bland

Abstract Research Question How concentrated is the total harm of offences with detected offenders (identified suspects) among the complete list of all detected offenders in a given year in an English police agency, and how consistent is the list of highest-harm “felonious few” offenders from one year to the next? Data Characteristics of 327,566 crimes and 39,545 unique offenders as recorded by Northamptonshire Police in 7 years from 2010 to 2016 provide the basis for this analysis. Methods Crime and offender records were matched to harm weightings derived from the Cambridge Crime Harm Index (Sherman et al. 2016a; Sherman et al., Policing, 10(3), 171–183, 2016b). Descriptive statistics summarize a concentration of harm identifying the felonious few, changes over time in membership of the “few”, offender typologies and tests for escalation of severity, frequency and intermittency across repeated offences. Findings Crime harm is much more concentrated among offenders than crime volume: 80% of crime harm that is identified to an offender is linked to a felonious few of just 7% of all detected offenders. While chronic repeat offenders are the majority contributors to harm totals of this group, those with the most general range of offence types contribute the most harm. Individual members of the felonious few rarely maintain that position year on year; over 95% of each year’s list is composed of individuals not present in previous years. Within individual crime histories, we observe a pattern of de-escalation in crime harm per offence over time. “One-time” offenders, those with just one crime record, typically made up a third of the felonious few in both number and harm contribution. Conclusions These findings demonstrate the potential to target a small number of repeat offenders for harm reduction strategies using a metric of total crime severity, not just volume, despite a substantial portion of crime harm caused by one-time offenders that may be largely unpredictable.


2021 ◽  
Author(s):  
Robert G. Maunder ◽  
Natalie D. Heeney ◽  
Jonathan J. Hunter ◽  
Gillian Strudwick ◽  
Lianne P. Jeffs ◽  
...  

Abstract Background. The mental health effects of healthcare work during the COVID-19 pandemic have been substantial, but it is not known how long they will persist. This study aimed to determine if hospital workers’ burnout and psychological distress increased monotonically over one year, during which waves of case numbers and hospitalizations waxed and waned, or followed some other pattern.Methods. A prospective longitudinal survey was conducted at four time-points over one year in a cohort of 538 hospital workers and learners, which included validated measures of burnout (emotional exhaustion scale of Maslach Burnout Inventory) and psychological distress (K6). Repeated measures ANOVA tested changes over time and differences between subjects by occupational role and age. The direction and magnitude of changes over time were investigated by plotting rates of high scores (using cut-offs) at each time-point compared to case rates of COVID-19 in the city in which the study took place. Results. There were significant changes in emotional exhaustion over time (F = 4.6, p = .004) and significant effects of occupational role (F = 11.4, p < .001) and age (F = 12.3, p < .001). The rate of high burnout was highest in nurses, followed by other healthcare professionals, other clinical staff, and lowest in non-clinical staff. Peak rates of high burnout occurred at the second or third measurement point for each occupational group, with lower rates at the fourth measurement point. Similarly to the results for emotional exhaustion, rates of high psychological distress peaked at the winter 2021 or spring 2021 measurement point in each occupational group and were highest in nurses.Conclusions. Neither emotional exhaustion nor psychological distress was rising monotonically. Burnout and psychological distress were consistently related to occupational role and were highest in nurses. Although emotional exhaustion improved as the case rate of COVID-19 decreased, rates of high emotional exhaustion in nurses and other healthcare professionals remained higher than was typically measured in hospital-based healthcare workers prior to the pandemic. Ongoing monitoring of healthcare workers’ mental health is warranted. Organizational and individual interventions to support healthcare workers continue to be important.


2019 ◽  
Vol 8 (4) ◽  
pp. 434 ◽  
Author(s):  
Miriam Donate-Manzanares ◽  
Teresa Rodríguez-Cano ◽  
Juan Gómez-Salgado ◽  
Julián Rodríguez-Almagro ◽  
Antonio Hernández-Martínez ◽  
...  

(1) Background: To evaluate women’s satisfaction with the care received during childbirth undergoing labour and how this changes over time. (2) Methods: An observational, multicentre and longitudinal study in two public hospitals of Spain with a convenience sample of 248 women during the post-partum period. Satisfaction was evaluated using the Intrapartal-Specific Quality from the Patient’s Perspective questionnaire. Socio-demographic and clinical variables were considered. A bivariate analysis evaluated the relationship between satisfaction and the recorded variables to compare the hypotheses, and also to know if there were any significant differences between the scores obtained at the various evaluated time points (three days, 15 days, one year postpartum). The multivariate analysis by binary logistic regression helped complete the study about the variables related to the level of satisfaction; (3) Results: The mean scores for satisfaction at each time point were high, and they lowered with time. The bivariate analysis showed an association between satisfaction and the following variables: ‘mother’s place of birth’, ‘level of education’, ‘type of labour onset’, ‘type of birth’ and ‘type of perineal trauma’. For the multivariate analysis, women who gave birth vaginally, began labour spontaneously and had an epidural were more satisfied than those who did not; (4) Conclusions: Women seemed to obtain good levels of satisfaction with the care they received. Even so, based on continuously improved quality, we proposed some improvement measures, particularly regarding the physical environment and the information offered to patients. It is important to know at what time experience while giving birth should be evaluated as scores can lower with time as part of its normal evolution.


VASA ◽  
2015 ◽  
Vol 44 (5) ◽  
pp. 355-362 ◽  
Author(s):  
Marie Urban ◽  
Alban Fouasson-Chailloux ◽  
Isabelle Signolet ◽  
Christophe Colas Ribas ◽  
Mathieu Feuilloy ◽  
...  

Abstract. Summary: Background: We aimed at estimating the agreement between the Medicap® (photo-optical) and Radiometer® (electro-chemical) sensors during exercise transcutaneous oxygen pressure (tcpO2) tests. Our hypothesis was that although absolute starting values (tcpO2rest: mean over 2 minutes) might be different, tcpO2-changes over time and the minimal value of the decrease from rest of oxygen pressure (DROPmin) results at exercise shall be concordant between the two systems. Patients and methods: Forty seven patients with arterial claudication (65 + / - 7 years) performed a treadmill test with 5 probes each of the electro-chemical and photo-optical devices simultaneously, one of each system on the chest, on each buttock and on each calf. Results: Seventeen Medicap® probes disconnected during the tests. tcpO2rest and DROPmin values were higher with Medicap® than with Radiometer®, by 13.7 + / - 17.1 mm Hg and 3.4 + / - 11.7 mm Hg, respectively. Despite the differences in absolute starting values, changes over time were similar between the two systems. The concordance between the two systems was approximately 70 % for classification of test results from DROPmin. Conclusions: Photo-optical sensors are promising alternatives to electro-chemical sensors for exercise oximetry, provided that miniaturisation and weight reduction of the new sensors are possible.


2016 ◽  
Vol 37 (3) ◽  
pp. 181-193 ◽  
Author(s):  
Aire Mill ◽  
Anu Realo ◽  
Jüri Allik

Abstract. Intraindividual variability, along with the more frequently studied between-person variability, has been argued to be one of the basic building blocks of emotional experience. The aim of the current study is to examine whether intraindividual variability in affect predicts tiredness in daily life. Intraindividual variability in affect was studied with the experience sampling method in a group of 110 participants (aged between 19 and 84 years) during 14 consecutive days on seven randomly determined occasions per day. The results suggest that affect variability is a stable construct over time and situations. Our findings also demonstrate that intraindividual variability in affect has a unique role in predicting increased levels of tiredness at the momentary level as well at the level of individuals.


2007 ◽  
Author(s):  
Miranda Olff ◽  
Mirjam Nijdam ◽  
Kristin Samuelson ◽  
Julia Golier ◽  
Mariel Meewisse ◽  
...  

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