scholarly journals Relationship of SARS-CoV-2 Pandemic with Blood Groups

2021 ◽  
pp. 1-7
Author(s):  
Didar Yanardag Acik ◽  
Mehmet Bankir
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Clinical Symptoms ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Direct Role ◽  
Angiotensin Converting Enzyme 2 ◽  
Healthy Donors ◽  
Relationship Of ◽  
Group Distribution

<b><i>Introduction:</i></b> SARS-CoV attaches to human angiotensin-converting enzyme 2 receptor with the spike protein and infects cells. It can play a direct role in infection by acting as a receptor and/or co-receptor for blood group antigens, microorganisms, parasites, and viruses. <b><i>Objectives:</i></b> We aimed to compare the blood group distribution of patients with SARS-CoV-2 infection admitted to hospital and that of healthy donors. <b><i>Methods:</i></b> A total of 823 patients with a positive SARS-CoV-2 test and clinical symptoms were included in the study. The results were compared with the normal blood group distribution in the region. <b><i>Results:</i></b> While the prevalence of COVID-19 in the A, B, and AB blood groups was higher than that in the healthy blood donors, it was lower in the O blood group (<i>p</i> = 0.009). The distribution of demographic and clinical characteristics based on blood groups did not differ significantly. <b><i>Conclusion:</i></b> Our results are in agreement with other studies suggesting that blood group O individuals are somewhat more resistant to clinically overt infection with SARS-CoV-2 than other blood groups. However, this tendency is not sufficiently established to allow special prophylaxis recommendations for non-O individuals.

scholarly journals Associations between seroprevalence of Helicobacter pylori and ABO/rhesus blood group antigens in healthy blood donors in southwest Iran

2021 ◽  
Vol 49 (12) ◽  
pp. 030006052110588
Author(s):  
Azar Dokht Khosravi ◽  
Mehrandokht Sirous ◽  
Morteza Saki ◽  
Sakineh Seyed-Mohammadi ◽  
Seyed Reza Modares Mousavi ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Blood Type ◽  
Enzyme Linked Immunosorbent Assay ◽  
Blood Group Antigens ◽  
Chi Square ◽  
Cytotoxin Associated Gene A ◽  
H Pylori

Objective To investigate correlations between ABO/rhesus (Rh) blood group antigens and anti- Helicobacter pylori and anti-cytotoxin-associated gene A (CagA) seropositivity in blood donors. Methods A total of 311 blood donors were enrolled. ABO and Rh blood groups were determined using hemagglutination tests. Specific anti- H. pylori IgG and anti-CagA IgG antibodies in sera were quantitated by enzyme-linked immunosorbent assay. Correlations between blood groups and anti- H. pylori and anti-CagA seropositivity were evaluated using the Chi-square test. Results O+ was the most frequent blood type (38%, n = 118). Anti- H. pylori IgG seropositivity was observed in 240 (77.2%) blood donors, while anti-CagA IgG seropositivity was observed in 132 (42.5%) blood donors. Although seropositivity rates for both anti- H. pylori and anti-CagA IgG were higher in individuals with blood type O, no statistically significant associations were observed between seropositivity and any ABO/Rh blood groups. Conclusion Individuals with blood type O may have higher rates of H. pylori seropositivity.

scholarly journals Distribution of RH and Kell (K) blood group antigens among blood donors in a tertiary care hospital of Jammu region, India

2019 ◽  
Vol 7 (4) ◽  
pp. 1308 ◽  
Author(s):  
Irm Yasmeen ◽  
Meena Sidhu ◽  
Ibrar Ahmed
Keyword(s):  
Ethnic Groups ◽  
Blood Group ◽  
Blood Donors ◽  
Tertiary Care ◽  
Data Bank ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Red Cell ◽  
Cell Antigen ◽  
K Antigen

Background: Knowledge about the frequency of red cell antigen phenotype is very important for the creation of donor data bank and to minimize the risk of alloimmunization. This requires the determination of immunological characteristics of blood products and blood recipients by performing phenotyping of clinically significant blood group antigens. The aims and objectives were to study the distribution of Rh and Kell (K) antigen among blood donors of different ethnic groups in a tertiary care hospital.Methods: This was prospective observational cross sectional one-point analysis study which was carried out over a period of one year with effect from November 2015 to October 2016 in the Postgraduate Department of Immunohematology and Blood Transfusion Medicine, Shri Maharaja Gulab Singh (SMGS) Hospital, Government Medical College, Jammu and Kashmir, India. It comprised of voluntary and replacement donors and categorized into different ethnic groups i.e Dogras, Gujjar Muslims, Non-Gujjar Muslims, Kashmiri Pandits, Sikhs and Christian. Donors selection criteria was as per Drug and Cosmetic Act.Results: A total of 500 (Five hundred) blood samples from the donors of all blood groups were typed for the presence of Rh (D, C, E, c, e) and Kell (K) antigens. Out of these 500 samples, 420 were antigen typed by conventional tube technique and 80 samples were typed by column agglutination technique using glass beads. As per ethnicity, maximum donors were Dogras (74%) followed by Non-Gujjar Muslims (9.4%), Gujjar Muslims (9%), Sikhs (5.6%), Kashmiri Pandits (1.4%) and Christians were the least in frequency (0.6%). On phenotyping for Rh and Kell antigens ‘e’ antigen have the ubiquitous distribution and was found to have the highest frequency 486 (97.2%) followed by ‘D’ antigen 472 (94.4%), ‘C’ antigen 426 (85.2%), ‘c’ antigen 320 (64.0%) and ‘E’ antigen 103 (20.6%). Overall frequency of Kell (K) antigen was 2.6%.Conclusions: Knowledge of red cell antigen phenotype frequencies in a population with different ethnic groups can help in creating donor data bank and database for the distribution of blood groups for preparing inhouse cell panels and providing proper antigen compatible blood for patients with multiple alloantibodies and also reduce the risk of RBC antigen alloimmunization along with their complications.

scholarly journals PREVALENCE OF ABO AND RHESUS BLOOD GROUPS IN BLOOD DONORS. A STUDY FROM A TERTIARY CARE TEACHING HOSPITAL S.V.R.R.GOVT. GENERAL HOSPITAL IN RAYALASEEMA REGION OF ANDHRA PRADESH, TIRUPATI.

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Vijay Lakshmi ◽  
Dr. Durga Prasad Palla ◽  
Dr. D Surendra Babu ◽  
Dr. Chittooru Chandra Sekhar
Keyword(s):  
General Hospital ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Donation ◽  
Blood Groups ◽  
Blood Component ◽  
Blood Group Antigens ◽  
Age Group ◽  
Group Frequency ◽  
Agglutination Method

Back ground: The ABO and Rhesus –D blood group are the major blood group systems. The frequency of four main blood group systems varies in population throughout the world and even in different parts of the country. ABO & Rh blood group antigens play a Vital role in immunologic safety of whole blood and blood component transfusion and also useful in population genetic studies, in resolving medico legal issues. Aim: This study is aimed to document the frequency and distribution pattern of ABO and Rh among blood donors in S.V.R.R.Govt. General Hospital, Tirupati. Study Design: It is a retrospective record based study carried out at Model blood bank S.V.R.R.Govt. General Hospital Tirupati from January 2014 to December 2015. Material and Methods: The study was conducted on 13,040 donors. ABO and Rh typing was done by using slide agglutination method with antisera ABO and Rh (tulip Diag). Doubtful cases were confirmed by tube agglutination method and reverse grouping by using pooled A& B cells. The age group and sex of donors and frequency of ABO and Rh blood groups were reported in simple percentages. Results: In the present study the most common blood group was ‘O’ 5505 (42.2%) and least common being AB 778 (5.96%). The prevalence of Rh positive and negative distribution in the study population is 12267(94.07%) and 773(5.93%) respectively. Predominant donors belonged to age group between 18-35 years (85.37 %).Male donors (97.88%) are common than female donors (2.12%) with ratio. Blood group frequency with respect to ABO and Rh was found to be O>B>A>AB. Conclusion:   O positive blood group is significantly high  in our population  while AB Iis least.. Blood donation by females appears to be low provably because of illiteracy, malnutrition and social taboo. So female donor need to be motivated for blood donation.  Knowledge of frequencies of different blood groups is very important for blood banks and transfusion service polices for better use and good inventory of blood units. Key words: Blood groups ABO, Rh

PROSPECTIVE OBSERVATIONAL STUDY TO ASSESS ASSOCIATION OF BLOOD GROUP ANTIGENS AND RISK OF CORONAVIRUS INFECTION CONDUCTED IN A TERTIARY CENTRE.

2021 ◽  
pp. 10-11
Author(s):  
Lubna Khan ◽  
Mohd Fahimuddin ◽  
Samarjeet Kaur ◽  
Chayanika Kala
Keyword(s):  
Health Care ◽  
Blood Group ◽  
Health Care Workers ◽  
Blood Donors ◽  
Blood Groups ◽  
P Value ◽  
Blood Group Antigens ◽  
Care Workers ◽  
Group Frequency ◽  
Coronavirus Infection

Purpose: COVID-19 has caused large scale morbidity and mortality. Assessment of frequency of blood groups in COVID-19 to investigate its susceptibility in different blood groups will help in risk stratication and its better understanding. Aims: To assess association between blood group antigens and coronavirus infection. Settings and Design: Blood group of COVID-19 patients was determined and was compared with blood group of blood donors over a period of 23 months. Blood group of both Ccovid-19 positive and negative health care workers was also compared. Methods and Material: Blood group determination was done in 1559 COVID-19 patients, out of which 81 were health care workers. Blood group of 754 COVID-19 negative health care workers was also determined. Gel column technique was used for blood grouping. Blood group frequency of COVID-19 patients was compared with blood group frequency of blood donors over a period of 23 months. Statistical analysis used: Odds ratio, 95% condence limit, z statistic and p value were calculated using online software available at https://www.medcalc.org/calc/odds_ratio.php. p value less than 0.05 was considered signicant. Results: B+ is most prevalent blood group in blood donors hence it was the most frequent blood group encountered in COVID19 patients, No signicant difference was noted in frequency of blood groups of COVID-19 patients and blood donors. Similar results were obtained after comparison of blood group in COVID-19 positive and negative Conclusions: No blood group is immune to SARS-CoV-2. Hence there should be universal compliance of sanitization protocols and vaccination

scholarly journals Association of transfusion transmitted infections with ABO and Rh D blood group system in healthy blood donors: a retrospective analysis

2020 ◽  
Vol 7 (11) ◽  
pp. 4444
Author(s):  
Satya Prakash ◽  
Dibyajyoti Sahoo ◽  
Debasish Mishra ◽  
Sumansudha Routray ◽  
Gopal Krushna Ray ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Public Health Approach ◽  
Blood Group System ◽  
Chi Square ◽  
Healthy Donors ◽  
Chi Square Test ◽  
Group A

Background: Transfusion transmitted infections (TTIs) involves several adverse consequences. Studies have shown that ABO blood groups have some association with various infectious and non-infectious diseases. Few blood groups even can act as a receptor and ligand for infectious agents. The objective of the study was to find out any significant association of TTIs with various ABO and Rh D blood group system.Methods: This retrospective study was conducted from July 2016 to October 2018. Blood donors’ blood was tested for ABO and Rh D grouping and five mandatory TTI markers as per Drugs and Cosmetics Act. Chi-square test was performed to look for any association of TTIs with ABO and Rh D blood group.Results: 10,510 healthy donors were screened for TTI and 199 (1.89%) were positive for various TTIs. Hepatitis B had maximum prevalence (102 cases, 0.97%) followed by Hepatitis C (44 cases, 0.41%) and HIV (37 cases, 0.35%). Maximum TTI seroreactive donors were found among ‘B’ blood group (2.21%, 77 cases) followed group ‘A’ donors (2.16%, 53 cases), ‘O’ donors (1.57%, 60 cases) and ‘AB’ donors (1.17%, 9 cases), respectively. However, the risk of association of TTI was not statistically significant with ABO and Rh D blood group.Conclusions: Although no significant association was observed between ABO and Rh D blood groups with TTIs, Hepatitis B was found to be most common infection in blood donors. This high prevalence points towards critical need of comprehensive public health approach to achieve elimination of TTI.

scholarly journals ABO, Rhesus blood groups and transfusion-transmitted infections among blood donors in Gabon

2018 ◽  
Vol 13 (1) ◽  
pp. 12 ◽  
Author(s):  
Christ-Dominique Ngassaki-Yoka ◽  
Jophrette Mireille Ntsame Ndong ◽  
Cyrille Bisseye
Keyword(s):  
Blood Group ◽  
Blood Donor ◽  
Representative Sample ◽  
Blood Donors ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Donor Population ◽  
Monospecific Antisera

Background: Few studies focused on the study of blood groups in Gabon. This study aimed to determine the phenotypic frequency of ABO and Rhesus antigens in blood donors of Libreville and to assess the association between ABO blood groups and transfusion-transmitted infections.Materials and Methods: The study of ABO and Rhesus blood groups concerned 4,744 blood donors. ABO and Rhesus phenotyping were obtained using monoclonal monospecific antisera: anti-A, anti-B, anti-AB, anti-D, anti-E, anti-C, anti-c, and anti-e with an automate (QWALYS® 3, DIAGAST, France) or a card gel (ID Card, BIO-RAD) according to manufacturer’s instructions.Results: The phenotypic frequency of blood group antigens A, B, AB and O were respectively 21.0%; 17.6%; 2.6% and 58.9%. Those of rhesus antigens D, d, C, c, E and e were 97.7%; 2.3%; 15.9%; 99.9%; 17.6%; 99.3%, respectively. The prevalence of ABO and Rh antigens in Gabonese donors reported here are significantly different from those of neighboring countries. No association was found between the prevalence of HIV, HCV and syphilis and ABO blood groups. Instead, HBV seroprevalence was twice as high among non-O blood groups donors compared with blood group O donors [OR = 2 (CI 1.26 to 3.2), p = 0.003].Conclusions: This study provides new data on phenotypic frequency of ABO and Rh blood groups in a representative sample of the Gabonese blood donor population. It suggests a significant association between ABO blood group and HBV infection.

scholarly journals The Higher Frequency of Blood Group B in a Brazilian Population with HIV Infection

2013 ◽  
Vol 7 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Tor Gunnar Hugo Onsten ◽  
Sidia Maria Callegari-Jacques ◽  
Luciano Zubaran Goldani
Keyword(s):  
Hiv Infection ◽  
Blood Group ◽  
Blood Donors ◽  
Binding Capacity ◽  
Blood Groups ◽  
Viral Envelope ◽  
Blood Type ◽  
Blood Group Antigens ◽  
Group B

Objective:To analyze the frequency of and odds for and against HIV infection based on ABO blood type in a large sample of blood donors.Background:Coevolution between pathogens and hosts may explain the ABO system of polymorphisms. HIV-infected cells add ABO(H) blood group antigens to the viral envelope. Naturally occurring antibodies against ABO(H) antigens that are present in normal human sera are able to neutralize ABO-expressing HIVin vitro. Blood donors are ideal for studying blood groups and HIV infectionin vivobecause all donors are routinely typed and tested.Methods:All blood donors who donated blood between 1994 and 2010 were tested for HIV (ELISA antibody tests and Western blot test or immunofluorescence testing) and were ABO typed (direct and reverse grouping tests). HIV infection based on the ABO blood group was analyzed using the chi-square test and game theory.Results:The total number of examined blood donors during this period was 271,410, of whom 389 were infected with HIV. B-group donors were more infected than non-B donors (p= 0.006).Conclusions:A more restricted antigen recognition capacity of anti-Galα1-3Gal in blood groups AB and B and a weaker antigen-binding capacity of anti-A antibodies may contribute to a higher frequency of HIV infection in blood group B.

Interrelations of Thrombo-Embolic Diseases and Blood-Group Distribution

1963 ◽  
Vol 09 (02) ◽  
pp. 472-474 ◽  
Author(s):  
W Dick ◽  
W Schneider ◽  
K Brockmüller ◽  
W Mayer
Keyword(s):  
Normal Distribution ◽  
Blood Group ◽  
Blood Groups ◽  
The Other ◽  
Other Hand ◽  
Group Distribution

SummaryA comparison between the repartition of the blood groups in 461 patients suffering from thromboembolic disorders and the normal distribution has shown a statistically ascertained predominance of the group A1. On the other hand the blood groups 0 and A2 are distinctly less frequent than in the normal distribution.

ABO and Rhesus (D) Blood Group Distribution among Blood Donors in Rural South Haryana (Mewat-Region): A 5 Years Retrospective Study

2018 ◽  
Vol 4 (3) ◽  
Author(s):  
Sudheer Singh ◽  
Shailesh Kumar Mishra ◽  
Shivani Kalhan ◽  
Puja Sharma ◽  
Rahul N Satarkar ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Blood Group ◽  
Blood Donors ◽  
Rural South ◽  
Group Distribution

scholarly journals Correlation of ABO Blood Groups and Rh Factor with The Severity of Generalized Chronic Periodontitis: Across Sectional Study in Riyadh, Saudi Arabia

2019 ◽  
Vol 7 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Diana Mostafa ◽  
Essam I. Elkhatat ◽  
Pradeep Koppolu ◽  
Muna Mahgoub ◽  
Esam Dhaifullah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Blood Group ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group I

BACKGROUND: The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases. AIM: Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor. METHODS: A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever). RESULTS: The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive. CONCLUSION: Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.

Sign in / Sign up

Export Citation Format

Share Document