scholarly journals PREVALENCE OF ABO AND RHESUS BLOOD GROUPS IN BLOOD DONORS. A STUDY FROM A TERTIARY CARE TEACHING HOSPITAL S.V.R.R.GOVT. GENERAL HOSPITAL IN RAYALASEEMA REGION OF ANDHRA PRADESH, TIRUPATI.

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Vijay Lakshmi ◽  
Dr. Durga Prasad Palla ◽  
Dr. D Surendra Babu ◽  
Dr. Chittooru Chandra Sekhar
Keyword(s):  
General Hospital ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Donation ◽  
Blood Groups ◽  
Blood Component ◽  
Blood Group Antigens ◽  
Age Group ◽  
Group Frequency ◽  
Agglutination Method

Back ground: The ABO and Rhesus –D blood group are the major blood group systems. The frequency of four main blood group systems varies in population throughout the world and even in different parts of the country. ABO & Rh blood group antigens play a Vital role in immunologic safety of whole blood and blood component transfusion and also useful in population genetic studies, in resolving medico legal issues. Aim: This study is aimed to document the frequency and distribution pattern of ABO and Rh among blood donors in S.V.R.R.Govt. General Hospital, Tirupati. Study Design: It is a retrospective record based study carried out at Model blood bank S.V.R.R.Govt. General Hospital Tirupati from January 2014 to December 2015. Material and Methods: The study was conducted on 13,040 donors. ABO and Rh typing was done by using slide agglutination method with antisera ABO and Rh (tulip Diag). Doubtful cases were confirmed by tube agglutination method and reverse grouping by using pooled A& B cells. The age group and sex of donors and frequency of ABO and Rh blood groups were reported in simple percentages. Results: In the present study the most common blood group was ‘O’ 5505 (42.2%) and least common being AB 778 (5.96%). The prevalence of Rh positive and negative distribution in the study population is 12267(94.07%) and 773(5.93%) respectively. Predominant donors belonged to age group between 18-35 years (85.37 %).Male donors (97.88%) are common than female donors (2.12%) with ratio. Blood group frequency with respect to ABO and Rh was found to be O>B>A>AB. Conclusion:   O positive blood group is significantly high  in our population  while AB Iis least.. Blood donation by females appears to be low provably because of illiteracy, malnutrition and social taboo. So female donor need to be motivated for blood donation.  Knowledge of frequencies of different blood groups is very important for blood banks and transfusion service polices for better use and good inventory of blood units. Key words: Blood groups ABO, Rh

PROSPECTIVE OBSERVATIONAL STUDY TO ASSESS ASSOCIATION OF BLOOD GROUP ANTIGENS AND RISK OF CORONAVIRUS INFECTION CONDUCTED IN A TERTIARY CENTRE.

2021 ◽  
pp. 10-11
Author(s):  
Lubna Khan ◽  
Mohd Fahimuddin ◽  
Samarjeet Kaur ◽  
Chayanika Kala
Keyword(s):  
Health Care ◽  
Blood Group ◽  
Health Care Workers ◽  
Blood Donors ◽  
Blood Groups ◽  
P Value ◽  
Blood Group Antigens ◽  
Care Workers ◽  
Group Frequency ◽  
Coronavirus Infection

Purpose: COVID-19 has caused large scale morbidity and mortality. Assessment of frequency of blood groups in COVID-19 to investigate its susceptibility in different blood groups will help in risk stratication and its better understanding. Aims: To assess association between blood group antigens and coronavirus infection. Settings and Design: Blood group of COVID-19 patients was determined and was compared with blood group of blood donors over a period of 23 months. Blood group of both Ccovid-19 positive and negative health care workers was also compared. Methods and Material: Blood group determination was done in 1559 COVID-19 patients, out of which 81 were health care workers. Blood group of 754 COVID-19 negative health care workers was also determined. Gel column technique was used for blood grouping. Blood group frequency of COVID-19 patients was compared with blood group frequency of blood donors over a period of 23 months. Statistical analysis used: Odds ratio, 95% condence limit, z statistic and p value were calculated using online software available at https://www.medcalc.org/calc/odds_ratio.php. p value less than 0.05 was considered signicant. Results: B+ is most prevalent blood group in blood donors hence it was the most frequent blood group encountered in COVID19 patients, No signicant difference was noted in frequency of blood groups of COVID-19 patients and blood donors. Similar results were obtained after comparison of blood group in COVID-19 positive and negative Conclusions: No blood group is immune to SARS-CoV-2. Hence there should be universal compliance of sanitization protocols and vaccination

scholarly journals Assessing ABO/Rh Blood Group Frequency and Association with Asymptomatic Malaria among Blood Donors Attending Arba Minch Blood Bank, South Ethiopia

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Getaneh Alemu ◽  
Mohammedaman Mama
Keyword(s):  
Blood Group ◽  
Malaria Infection ◽  
Blood Donors ◽  
Blood Groups ◽  
High Rate ◽  
Abo Blood Group ◽  
Asymptomatic Malaria ◽  
Abo Blood Groups ◽  
Group Frequency ◽  
Rh Blood Group

Background. Determination of the various ABO/Rh blood group distributions and their association with malaria infection has paramount importance in the context of transfusion medicine and malaria control. Methods. Facility based cross-sectional study was conducted from February to June, 2015, to assess ABO/Rh blood groups distribution and their association with asymptomatic malaria. A structured questionnaire was used to collect data. Blood grouping was done using monoclonal antibodies. Thin and thick blood films were examined for Plasmodium parasites. Data were analyzed using SPSS version 20.0. Results. A total of 416 blood donors participated with median age of 22±0.29 (median ± standard error of the mean). Distribution of ABO phenotypes, in decreasing order, was O (175, 42.1%), A (136, 32.7%), B (87, 20.9%), and AB (18, 4.3%). Most of them were Rh+ (386, 92.8%). The overall malaria prevalence was 4.1% (17/416). ABO blood group is significantly associated with malaria infection (P=0.022). High rate of parasitemia was seen in blood group O donors (6.899, P=0.003) compared to those with other ABO blood groups. Conclusion. Blood groups O and AB phenotypes are the most and the least ABO blood groups, respectively. There is significant association between ABO blood group and asymptomatic malaria parasitemia.

scholarly journals Prevalence of ABO, Rh and KELL Blood Group Types and Transfusion- Transmissible Infections (TTI) among Blood Donors in Najran City, Saudi Arabia

2021 ◽  
Vol 14 (02) ◽  
pp. 1065-1076
Author(s):  
Osama M Alshehri ◽  
Mohammed H Nahari ◽  
Elhashimi E Hassan ◽  
Musab F Alqahtani ◽  
Turki H Awaji
Keyword(s):  
Saudi Arabia ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Blood Group ◽  
Blood Donation ◽  
Complete Blood Count ◽  
Blood Groups ◽  
Type I ◽  
Blood Group Antigens ◽  
Safe Blood

The knowledge of Red blood cells polymorphism and blood group antigens prevalence at the local and regional levels is necessary for safe blood transfusion services. This study was aimed to estimate the prevalence of significant blood group phenotypes like ABO, Rh, and Kell among the Najran people of Saudi Arabia. The transfusion transmittable infection (TTI) rate and blood abnormalities among various blood types were assessed to ensure safe blood transfusion. ABO and Rh blood prevalence (n=970) and Rh phenotype polymorphism were estimated in over 531 unrelated donors. The blood samples were screened for certain TTIs like AHBC- Anti-hepatitis B core, HTLV-1- human T-lymphotropic virus type I, HCV- hepatitis C virus, HBsAg- Hepatitis B antigen, HIV- Human immunodeficiency virus, SIC- Sickle cell, MP- Malaria parasite, and SYP- Syphilis. The selected samples were also observed for blood abnormalities by performing a complete blood count (CBC). Out of 970 subjects, 966 were males, and only 4 were females. The O>A>B>AB blood groups were identified with 46.89, 29.3, 9.1, and 2.38% prevalence among Rh-positive phenotype. While in the Rh system, 87.6% and 12.3% of Rh positive and Rh negative was observed. Among 953 samples, the prevalence of seropositive donors was approximately 5.66%. The screening showed about 5.036, 0.104, 0.314, 0.209, 2.18, 0.104, and 0.209% positivity for AHBC, HCV, HBsAg, HIV, SIC, MP, and SYP respectively. Results found that the frequency of D, C, E, c, and e were 99.9%, 67.98, 25.8, 77.9, 98.49%, respectively, in over 531 subjects. The e allele was more prevalent in Najran city. After observing the variations in the CBC parameters among the donors, it was perceived that about 28.78, 99.9, 29.41, and 31.6% of blood abnormalities were noticed for O, AB, B, and A blood groups, respectively. For blood banks and transfusion services, which play a significant role in the medical care of the patient, awareness of the distribution of the blood group is essential. Increasing consistency of blood donation programs would improve both donor satisfaction and motivation for potential donations of blood in near future.

scholarly journals Associations between seroprevalence of Helicobacter pylori and ABO/rhesus blood group antigens in healthy blood donors in southwest Iran

2021 ◽  
Vol 49 (12) ◽  
pp. 030006052110588
Author(s):  
Azar Dokht Khosravi ◽  
Mehrandokht Sirous ◽  
Morteza Saki ◽  
Sakineh Seyed-Mohammadi ◽  
Seyed Reza Modares Mousavi ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Blood Type ◽  
Enzyme Linked Immunosorbent Assay ◽  
Blood Group Antigens ◽  
Chi Square ◽  
Cytotoxin Associated Gene A ◽  
H Pylori

Objective To investigate correlations between ABO/rhesus (Rh) blood group antigens and anti- Helicobacter pylori and anti-cytotoxin-associated gene A (CagA) seropositivity in blood donors. Methods A total of 311 blood donors were enrolled. ABO and Rh blood groups were determined using hemagglutination tests. Specific anti- H. pylori IgG and anti-CagA IgG antibodies in sera were quantitated by enzyme-linked immunosorbent assay. Correlations between blood groups and anti- H. pylori and anti-CagA seropositivity were evaluated using the Chi-square test. Results O+ was the most frequent blood type (38%, n = 118). Anti- H. pylori IgG seropositivity was observed in 240 (77.2%) blood donors, while anti-CagA IgG seropositivity was observed in 132 (42.5%) blood donors. Although seropositivity rates for both anti- H. pylori and anti-CagA IgG were higher in individuals with blood type O, no statistically significant associations were observed between seropositivity and any ABO/Rh blood groups. Conclusion Individuals with blood type O may have higher rates of H. pylori seropositivity.

scholarly journals Distribution of RH and Kell (K) blood group antigens among blood donors in a tertiary care hospital of Jammu region, India

2019 ◽  
Vol 7 (4) ◽  
pp. 1308 ◽  
Author(s):  
Irm Yasmeen ◽  
Meena Sidhu ◽  
Ibrar Ahmed
Keyword(s):  
Ethnic Groups ◽  
Blood Group ◽  
Blood Donors ◽  
Tertiary Care ◽  
Data Bank ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Red Cell ◽  
Cell Antigen ◽  
K Antigen

Background: Knowledge about the frequency of red cell antigen phenotype is very important for the creation of donor data bank and to minimize the risk of alloimmunization. This requires the determination of immunological characteristics of blood products and blood recipients by performing phenotyping of clinically significant blood group antigens. The aims and objectives were to study the distribution of Rh and Kell (K) antigen among blood donors of different ethnic groups in a tertiary care hospital.Methods: This was prospective observational cross sectional one-point analysis study which was carried out over a period of one year with effect from November 2015 to October 2016 in the Postgraduate Department of Immunohematology and Blood Transfusion Medicine, Shri Maharaja Gulab Singh (SMGS) Hospital, Government Medical College, Jammu and Kashmir, India. It comprised of voluntary and replacement donors and categorized into different ethnic groups i.e Dogras, Gujjar Muslims, Non-Gujjar Muslims, Kashmiri Pandits, Sikhs and Christian. Donors selection criteria was as per Drug and Cosmetic Act.Results: A total of 500 (Five hundred) blood samples from the donors of all blood groups were typed for the presence of Rh (D, C, E, c, e) and Kell (K) antigens. Out of these 500 samples, 420 were antigen typed by conventional tube technique and 80 samples were typed by column agglutination technique using glass beads. As per ethnicity, maximum donors were Dogras (74%) followed by Non-Gujjar Muslims (9.4%), Gujjar Muslims (9%), Sikhs (5.6%), Kashmiri Pandits (1.4%) and Christians were the least in frequency (0.6%). On phenotyping for Rh and Kell antigens ‘e’ antigen have the ubiquitous distribution and was found to have the highest frequency 486 (97.2%) followed by ‘D’ antigen 472 (94.4%), ‘C’ antigen 426 (85.2%), ‘c’ antigen 320 (64.0%) and ‘E’ antigen 103 (20.6%). Overall frequency of Kell (K) antigen was 2.6%.Conclusions: Knowledge of red cell antigen phenotype frequencies in a population with different ethnic groups can help in creating donor data bank and database for the distribution of blood groups for preparing inhouse cell panels and providing proper antigen compatible blood for patients with multiple alloantibodies and also reduce the risk of RBC antigen alloimmunization along with their complications.

scholarly journals GAMBARAN PENDONOR DARAH DI UTD PMI KABUPATEN BANTUL TAHUN 2020

2021 ◽  
Vol 16 (3) ◽  
pp. 938-943
Author(s):  
Atik Dina Naseha ◽  
Nur’Aini Purnamaningsih ◽  
Kuswanto Hardjo
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Blood Donation ◽  
Secondary Data ◽  
Blood Type ◽  
Age Group ◽  
Social Scale ◽  
The Social ◽  
Male Sex ◽  
Activity Report

At the end of 2019, it was found that there was a very fast mutating virus called the Covid-19 virus, this virus causes diseases ranging from coughs to colds to death, efforts to prevent the spread of this virus by limiting the social scale of the community which causes a decrease in the number of blood donors which has an impact on the amount of blood stock in Blood Donation Unit. The objective of this study was to determine the description of blood donors based on blood type, gender, age, and type of donor at Blood Donation Unit Bantul Regency in 2020. This study was an activity report by observing secondary data obtained from Blood Donation Unit Bantul Regency. The number of donors was 8.212 donors, of which the number of donations from inside the building was 5.936 donors (72,28%), and the number of donations from mobile units was 2.276 donors (27,72%). The results showed that the majority of blood donors were blood group 0, which was 3.506 (42,69%), and the least blood type was AB, which was 468 (5.70%). The majority of the gender of the donor was male, namely 7.020 (85,48%), for female, 1.192 (14,52%). The majority of donors are aged 17-24 years, namely 1.738 (21,16%), and at least 65 years old 45 (0,55%). The majority of voluntary donors were 5.151 (62,73%), and the subtitute/ family donors were 1.034 (12,59%). There were 8.212 blood donors where the majority of blood group 0 was 3.506 (42,69%), male sex was 7.020 (85,48%), in the 17-24 year age group 1.738 (21,16%), and repeated voluntary donors were 5.151 (62,73%).

scholarly journals PHENOTYPIC FREQUENCIES OF ABO AND RH(D) BLOOD GROUPS AMONGST HEALTHY BLOOD DONORS IN BIKANER, RAJASTHAN

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Mamta Mehra
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Negative Control ◽  
Blood Groups ◽  
Standard Assumption ◽  
Agglutination Method ◽  
Hardy Weinberg Equilibrium ◽  
Group B ◽  
Antigen Antibody ◽  
Blood Grouping

Background & Objective: Practically, most important blood groups are A, B, O, AB and RhD(+/-), which are essential for right blood supply to the recipients and in various studies. The incidence of ABO and Rhesus (Rh) groups varies markedly in different parts of the world and in different races. The present study was aimed at determining the prevalence of ABO & RhD blood groups among healthy blood donors in Western Rajasthan. Material and Methods: At our centre, all the healthy blood donors were assessed and analyzed for ABO-Rh blood grouping during a period of previous 4 years (from January, 2015 to December, 2018). 119200 samples were checked for ABO and RhD blood grouping by manual saline antigen-antibody agglutination method using commercially prepared antisera antiA, antiB, antiAB, antiD, in house prepared reagent cells Acell, Bcell, Ocell and negative control. The results were reconfirmed on fully automated immunohematology analyzer (Galileo Neo, USA) with direct hemagglutination micro-well plates using antiA, antiB, antiD series-5, antiD Novaclone, Monoclonal control, Acell, Bcell and Ocell provided by the manufacturer. Discrepant samples were cross checked separately by column agglutination technique using DG Gel ABO/Rh-2D cards (Diagnostic Grifols S.A.) and tube technique. Results: We found that the most common blood group was B+ 39758 (33.35%) followed by O+, A+, AB+, B-, O-, A- and AB-. RhD negative donors were 10504 (8.81%) among the total donors. Phenotypic frequencies were expressed under the standard assumption of Hardy-Weinberg equilibrium. Conclusion: Present study concludes that the most common ABO phenotype found among healthy blood donors in Western Rajasthan (India) is group B with RhD negativity being 8.81%. Larger studies should be conducted to calculate antigenic, phenotypic and allelic frequencies in general population. Keywords: ABO-RhD blood group, Phenotype, Allele, Blood donors, hemagglutination.

scholarly journals ABO, Rhesus blood groups and transfusion-transmitted infections among blood donors in Gabon

2018 ◽  
Vol 13 (1) ◽  
pp. 12 ◽  
Author(s):  
Christ-Dominique Ngassaki-Yoka ◽  
Jophrette Mireille Ntsame Ndong ◽  
Cyrille Bisseye
Keyword(s):  
Blood Group ◽  
Blood Donor ◽  
Representative Sample ◽  
Blood Donors ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Donor Population ◽  
Monospecific Antisera

Background: Few studies focused on the study of blood groups in Gabon. This study aimed to determine the phenotypic frequency of ABO and Rhesus antigens in blood donors of Libreville and to assess the association between ABO blood groups and transfusion-transmitted infections.Materials and Methods: The study of ABO and Rhesus blood groups concerned 4,744 blood donors. ABO and Rhesus phenotyping were obtained using monoclonal monospecific antisera: anti-A, anti-B, anti-AB, anti-D, anti-E, anti-C, anti-c, and anti-e with an automate (QWALYS® 3, DIAGAST, France) or a card gel (ID Card, BIO-RAD) according to manufacturer’s instructions.Results: The phenotypic frequency of blood group antigens A, B, AB and O were respectively 21.0%; 17.6%; 2.6% and 58.9%. Those of rhesus antigens D, d, C, c, E and e were 97.7%; 2.3%; 15.9%; 99.9%; 17.6%; 99.3%, respectively. The prevalence of ABO and Rh antigens in Gabonese donors reported here are significantly different from those of neighboring countries. No association was found between the prevalence of HIV, HCV and syphilis and ABO blood groups. Instead, HBV seroprevalence was twice as high among non-O blood groups donors compared with blood group O donors [OR = 2 (CI 1.26 to 3.2), p = 0.003].Conclusions: This study provides new data on phenotypic frequency of ABO and Rh blood groups in a representative sample of the Gabonese blood donor population. It suggests a significant association between ABO blood group and HBV infection.

scholarly journals The Higher Frequency of Blood Group B in a Brazilian Population with HIV Infection

2013 ◽  
Vol 7 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Tor Gunnar Hugo Onsten ◽  
Sidia Maria Callegari-Jacques ◽  
Luciano Zubaran Goldani
Keyword(s):  
Hiv Infection ◽  
Blood Group ◽  
Blood Donors ◽  
Binding Capacity ◽  
Blood Groups ◽  
Viral Envelope ◽  
Blood Type ◽  
Blood Group Antigens ◽  
Group B

Objective:To analyze the frequency of and odds for and against HIV infection based on ABO blood type in a large sample of blood donors.Background:Coevolution between pathogens and hosts may explain the ABO system of polymorphisms. HIV-infected cells add ABO(H) blood group antigens to the viral envelope. Naturally occurring antibodies against ABO(H) antigens that are present in normal human sera are able to neutralize ABO-expressing HIVin vitro. Blood donors are ideal for studying blood groups and HIV infectionin vivobecause all donors are routinely typed and tested.Methods:All blood donors who donated blood between 1994 and 2010 were tested for HIV (ELISA antibody tests and Western blot test or immunofluorescence testing) and were ABO typed (direct and reverse grouping tests). HIV infection based on the ABO blood group was analyzed using the chi-square test and game theory.Results:The total number of examined blood donors during this period was 271,410, of whom 389 were infected with HIV. B-group donors were more infected than non-B donors (p= 0.006).Conclusions:A more restricted antigen recognition capacity of anti-Galα1-3Gal in blood groups AB and B and a weaker antigen-binding capacity of anti-A antibodies may contribute to a higher frequency of HIV infection in blood group B.

scholarly journals Relationship of SARS-CoV-2 Pandemic with Blood Groups

2021 ◽  
pp. 1-7
Author(s):  
Didar Yanardag Acik ◽  
Mehmet Bankir
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Clinical Symptoms ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Direct Role ◽  
Angiotensin Converting Enzyme 2 ◽  
Healthy Donors ◽  
Relationship Of ◽  
Group Distribution

<b><i>Introduction:</i></b> SARS-CoV attaches to human angiotensin-converting enzyme 2 receptor with the spike protein and infects cells. It can play a direct role in infection by acting as a receptor and/or co-receptor for blood group antigens, microorganisms, parasites, and viruses. <b><i>Objectives:</i></b> We aimed to compare the blood group distribution of patients with SARS-CoV-2 infection admitted to hospital and that of healthy donors. <b><i>Methods:</i></b> A total of 823 patients with a positive SARS-CoV-2 test and clinical symptoms were included in the study. The results were compared with the normal blood group distribution in the region. <b><i>Results:</i></b> While the prevalence of COVID-19 in the A, B, and AB blood groups was higher than that in the healthy blood donors, it was lower in the O blood group (<i>p</i> = 0.009). The distribution of demographic and clinical characteristics based on blood groups did not differ significantly. <b><i>Conclusion:</i></b> Our results are in agreement with other studies suggesting that blood group O individuals are somewhat more resistant to clinically overt infection with SARS-CoV-2 than other blood groups. However, this tendency is not sufficiently established to allow special prophylaxis recommendations for non-O individuals.

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