scholarly journals Blood Donation-Related Adverse Reactions: Results of an Online Survey among Donors in Germany (2018)

2021 ◽  
pp. 1-11
Author(s):  
Stefano Orru’ ◽  
Kay Poetzsch ◽  
Marcus Hoffelner ◽  
Margarethe Heiden ◽  
Markus B. Funk ◽  
...  

<b><i>Introduction:</i></b> According to German legislation, reports of suspected serious adverse reactions (AR) associated with the donation of blood and its components are continuously being evaluated by the Paul-Ehrlich-Institut. This survey aimed at providing a more complete picture of the AR associated with the donation of blood and blood components. <b><i>Materials and Methods:</i></b> Eligible donors had the opportunity to anonymously report all AR occurring during or after their last donation by completing an online questionnaire. Reported AR were classified according to the Standard for Surveillance of Complications Related to Blood Donation. Donors’ self-assessment of AR seriousness was compared with the official severity classification as laid down by German legislation. Besides a descriptive statistical analysis, a multiple logistic analysis was performed to identify risk factors for AR. <b><i>Results:</i></b> A total of 8,138 data records were evaluated. Slightly more males (57.9%) participated in the survey and, except for donors aged ≥60 years, all age groups were equally represented. The majority of participants were whole blood donors (85.4%), repeat donors (97.2%), and stayed under observation in the blood establishment (BE) for more than 5 min (63.1%) after donation. Most participants did not report any reaction (72.5%), whereas 2,237 reported at least one AR (27.5%), 475 of whom underwent apheresis and 1,762 donated whole blood. Most AR occurred after leaving the BE (64.4%). Only a minority of participants required medical treatment (5.1%) or assessed the experienced AR as serious (3.9%). The most frequently reported donor AR were haematoma and other local reactions (57.6%). Vasovagal reactions without and with loss of consciousness were developed in 17 and 2% of the participants, respectively, whilst 7.6% experienced citrate reactions. New AR (i.e., allergic reactions and symptoms associated with iron deficiency) were reported as well. The occurrence of AR was linked to risk factors (i.e., female gender, young age, first-time donation, and thrombocytapheresis). <b><i>Discussion:</i></b> This survey yielded a more comprehensive AR spectrum, revealed a prolonged time to symptom onset, and identified risk factors for AR. This novel information could be implemented in an amended informed consent addressing common and rare AR.

Author(s):  
Rosa M Sánchez-Casas ◽  
Ildefonso Fernández-Salas ◽  
Maricela Laguna-Aguilar ◽  
Jorge J Rodríguez-Rojas ◽  
Marcia L Medina-Ponce ◽  
...  

SUMMARY The prevalence of pediculosis in Mexican children was studied in San Nicolas and Tapachula, Mexico. A cross-sectional study included 888 students between six and 12 years old from two urban communities with an unequal socioeconomic status between September 2015 and March 2016. A Pearson χ2 and multivariate logistic analysis were carried out to associate risk factors to pediculosis. The overall prevalence of pediculosis from both localities was 23.9%. The female gender; long and medium hair; living with someone infested; previously infested by head lice and curling hair were variables linked to a significantly higher prevalence of pediculosis (p &lt; 0.01). Nevertheless, no significant differences were observed in the age groups, localities and socioeconomic status for human lice infection. Socioeconomic variables such as numbers of inhabitants, floors of house, beds and rooms; and parents’ qualification did not show a significative association for pediculosis. Health education in schools is needed for pediculosis prevention and remove the stigmatization of this disease related to poverty.


2021 ◽  
Vol 9 (11) ◽  
pp. 232596712110434
Author(s):  
Damien Sanfilippo ◽  
Charlotte Beaudart ◽  
Allan Gaillard ◽  
Stephen Bornheim ◽  
Olivier Bruyere ◽  
...  

Background: Despite the many studies on running-related injuries (RRIs), risk factors for injury remain unclear in the literature. Purpose: To investigate the risk factors of RRIs. Study Design: Case-control study; Level of evidence, 3. Methods: An online survey was conducted among 3669 injured and noninjured runners. Injury was defined as pain of various kinds, without attention to its consequences on running practice. The survey included 41 questions on 5 main categories—personal characteristics, daily lifestyle, training and running characteristics, practice of other sporting activities, and prevention habits—as well as information about the occurrence of RRI over the previous 12 months. Continuous and qualitative variables were analyzed by Student t test and chi-square test, respectively. Sixteen variables were selected for multivariate binary logistic analysis. Results: Among the 3669 runners, 1852 (50.5%) reported at least 1 injury over the previous 12 months. Overuse injuries were largely represented (60.6%). The variables associated with RRIs that remained significant in the fully adjusted model were previous injury (odds ratio [OR], 1.62; 95% CI, 1.42-1.86), higher weight (OR, 1.006; 95% CI, 1.00-1.012), competitive running (OR, 1.53; 95% CI, 1.19-1.98), running >2 h/wk (OR, 1.28; 95% CI, 1.01-1.62), running >20 km/wk (OR, 1.25; 95% CI, 1.001-1.55), and stretching before running (OR, 1.46; 95% CI, 1.25-1.71). Conclusion: Previous injury remains the most relevant risk factor for RRIs according to the current study and previous data. Many training characteristics seem to be involved but still have to be confirmed in view of conflicting data in the literature. Further research would help clinicians better understand RRIs and how to prevent them.


Author(s):  
Amro Bin Abdulrahman ◽  
Khalid Bin Abdulrahman ◽  
Randa Nouh

Background: The Saudi ministry of health (MOH) started the preventive measures very early on before having a single case of COVID-19. There were very few studies regarding the awareness and adherence to the preventive measures against COVID-19 among the Saudi population in the literature. Objectives: The study aims to examine the awareness and commitment to the strict Saudi government preventive measures against COVID-19. Methods: A cross-sectional online survey targeted Saudi and non-Saudi populations aged 18+ in March–April 2020. The online questionnaire was designed to explore the participant’s sociodemographic data, washing hygiene habits, the general level of awareness regarding COVID-19, and the extent to which they adhere to the government’s strict instructions. Results: Out of the 2958 participants in the survey, 23% washed their hands for between 20 and 30 s, 59.6% washed their hands after shaking hands with other people, 67.9% washed their hands after use of other’s utilities, 65.9% had appropriately followed the MOH recommended guidelines for home quarantine and social distancing. People in different age groups differed significantly on their practiced hygienic practices score p < 0.001. Respondents’ educational level had converged considerably and positively on their clean proper prevention practices score, f(2838.3) = 15.70. Conclusion: The majority of the participants adhere to the strict government instructions regarding COVID-19 as they have to obey the law. Health sector employees measured significantly greater hygienic preventive measures and precautions in comparison to other sectors. More public health efforts should increase hygienic best practice scores to achieve the best outcome.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 616-625
Author(s):  
Kamalli M ◽  
Kavitha S ◽  
Sangeetha A ◽  
Vishnupriya V ◽  
Gayathri R

Cardiovascular diseases (CVD) are becoming a serious health issue across the world and conventional risk factors are associated with lifestyle behaviours in all age groups. According to WHO, heart diseases are rapidly increasing in India and it is noted that CVD is not having any boundaries in terms of sex, socioeconomic or geography. The present study is aimed to determine the awareness of cardiovascular risk factors among working women. Self-administered questionnaire was prepared based on cardiovascular risk factors and circulated through an online survey link. The sample size was about 109 working women. The purpose of the study was explained in detail to the participants. The collected data were statistically analyzed using SPSS software. 89.9% of the population thought that working women are more prone to cardiovascular risk factors and 10.1% thought that working women are not prone to CVDs. 60.6% of the participants responded that PCOS could be a risk factor and remaining 39.4% responded that it is not a risk factor for CVD. The entire population answered that a healthy lifestyle and diet could reduce the risk of CVD. The Pearson Chi-square analysis showed that there is no association between the age group of the respondents and awareness of cardiovascular risk factors. To conclude, the awareness of the cardiovascular risk factors among working women was satisfactory.


2020 ◽  
Vol 66 (5) ◽  
pp. 504-511 ◽  
Author(s):  
Selçuk Özdin ◽  
Şükriye Bayrak Özdin

Background: The COVID-19 pandemic is having negative effects on societies’ mental health. Both the pandemic and the measures taken to combat it can affect individuals’ mental health. Aims: The purpose of this study was to evaluate the levels of depression, anxiety and health anxiety in Turkish society during the COVID-19 pandemic, and to examine the factors affecting these. Method: The study was performed using an online questionnaire. Participants were asked to complete a sociodemographic data form, the Hospital Anxiety and Depression Scale (HADS) and the Health Anxiety Inventory (HAI). The effects on depression, anxiety and health anxiety levels of factors such as age, sex, marital status, living with an individual aged above 60, the presence of a new Coronavirus+ patient among friends or relatives, previous and current psychiatric illness and presence of accompanying chronic disease were then investigated. Results: In terms of HADS cut-off points, 23.6% ( n = 81) of the population scored above the depression cut-off point, and 45.1% ( n = 155) scored above the cut-off point for anxiety. In regression analysis, female gender, living in urban areas and previous psychiatric illness history were found as risk factors for anxiety; living in urban areas was found as risk factor for depression; and female gender, accompanying chronic disease and previous psychiatric history were found as risk factors for health anxiety. Conclusion: The results of this cross-sectional study suggest that the groups most psychologically affected by the COVID-19 pandemic are women, individuals with previous psychiatric illness, individuals living in urban areas and those with an accompanying chronic disease. Priority might therefore be attached to these in future psychiatric planning.


Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Yoshihide Mitani ◽  
Noriko Yodoya ◽  
Hiroyuki Ohashi ◽  
Hirofumi Sawada ◽  
Masahiro Hirayama

Introduction: Out-of-hospital cardiac arrests (OHCA) of presumed cardiac origin witnessed by nonfamily members in the daytime are most effectively resuscitated in the youth, in which the impact of recently disseminated hands-only cardiopulmonary resuscitation (CPR) is poorly understood. Hypothesis: Dissemination of hands-only CPR is associated with the better outcome in school students and young adults after such OHCA. Methods: We investigated OHCA of presumed cardiac origin in the youth (Group A, 7-12y; group B, 13-18y; group C, 19-22y; group D, 23-35y) which are witnessed by nonfamily members in the daytime (6:00-17:59) during 2005-15 by using Japanese nationwide Utstein registry. Results: We recruited 1,646 pts, in which N of pts was 92 (A), 382 (B), 229 (C) and 943 (D); ventricular fibrillation (VF) as the initial rhythm (%) was 48, 70, 64, and 59; bystander’s CPR (%) was 81, 80, 71 and 68; hands-only/bystander’s CPR (%) was 32, 38, 57, 56; bystander’s automated external defibrillator (AED) (%) was 37, 44, 24 and 19; the favorable neurological outcome at 1 month (CPC1-2)(%) was 46, 49, 39 and 30. Compared with group D, %bystander’s CPR (p=.013 in A, <.001 in B), %bystander’s AED (<.001 in both), and %CPC1-2 (.005, <.001) was higher but %hands-only CPR(<.001 in both) was lower in A and B, independent of the calendar year. Compared with 2005-09, %hands-only CPR, %bystander’s AED and CPC1-2 were higher in all age groups (<.005 in all) in 2010-15. In multivariate logistic analysis (gender, age groups (vs D), CPR type (conventional or hands-only CPR vs no CPR), bystander’s AED, the initial VF, emergency response time, calendar year), hands-only CPR (p=.03), bystander’s AED(<.001), female gender(.045), initial VF (<.001), emergency response time (<.001), and calendar year (<.001) were independently associated with CPC1-2. Conclusions: The present investigation demonstrates that resuscitation and outcome parameters after OHCA of presumed cardiac origin were persistently better in school students than young adults and that %hands-only CPR, which was persistently lower in school students, was independently associated with the better outcome in the youth overall. This finding may give a clue to further improvement of the outcomes in school students after OHCA.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Seiji Shiota ◽  
Kazunari Murakami ◽  
Kunimitsu Inoue ◽  
Kyoko Yamamoto ◽  
Akiko Kuroda ◽  
...  

Aims. FSSG {frequency scale for the symptoms of gastroesophageal reflux disease (GERD)} was developed as a diagnostic tool for dysmotility and acid reflux symptoms. We first used FSSG to investigate the prevalence and risk factors for dysmotility and acid reflux symptoms and overlap of the two symptoms in a Japanese population. Methods. A cross-sectional survey was performed in Japanese underwent the routine medical examination. Dysmotility and acid reflux symptom were diagnosed by using FSSG. Subjects met both criteria were considered as overlap group. Results. Among 778 subjects, 395 persons were included in the final analyses. Dysmotility symptoms were found in 32.6% and acid reflux symptoms in 20.5%. Their overlap was found in 13.9% of all 395 subjects, which in 42.6% of dysmotility symptoms and 67.9% of acid reflux symptoms. Multiple logistic analysis showed that female gender was significantly associated with dysmotility symptoms compared with controls. Female gender, smoking, and hiatus hernia were significantly associated with overlap. Smoking was significantly associated with overlap compared with dysmotility symptoms alone and acid reflux symptoms alone. Conclusions. Overlap between dysmotility and acid reflux symptoms was common in Japan. Smoking was an independent risk factor for overlap among two symptoms.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zoya Fatima Rizwan Ladiwala ◽  
Rubaid Azhar Dhillon ◽  
Ibrahim Zahid ◽  
Omar Irfan ◽  
Muhammad Sharjeel Khan ◽  
...  

Abstract Background The Novel Coronavirus Disease (COVID-19) has created havoc globally as countries worldwide struggle to combat this pandemic. Since prevention and social isolation are known to be the only ways to prevent the spread of COVID-19, this has created challenges among the lower-middle income countries (LMIC) including Pakistan, as it battles between an under-resourced healthcare, an economic shutdown, and widespread myths and misconceptions. Therefore, a study was conducted to evaluate the knowledge, attitude and perceptions regarding COVID-19 as public understanding is vital to help facilitate the control of this outbreak. Methods A pre-validated online questionnaire was distributed among the general population of Pakistan from 1st to 12th June 2020. Descriptive statistics were analyzed using SPSS v25. Adequate knowledge was assigned as a score of > 4 (range: 0–8) and good perception as a score of > 3 (range: 0–5). Chi-square test was used to determine the significance of difference in knowledge and perception of COVID-19 with socio-demographic characteristics. Logistic regression analysis was run to identify factors associated with adequate knowledge and perception. P < 0.05 was considered as significant. Results A total of 1200 respondents participated in this study with a wide range of age groups and education. Majority of the respondents had adequate knowledge (93.3%) with a mean score of 6.59 ± 1.35, and good perception (85.6%) with a mean score of 4.29 ± 0.82. Significant differences in knowledge and perception were observed among genders, age groups, education and between students and employees in the healthcare and non-healthcare department. A multivariate analysis revealed a higher educational status and female gender to be significant predictors of adequate knowledge and perception. Conclusions Albeit the surge of COVID-19 cases in Pakistan, the participants demonstrated an overall adequate knowledge and good perception towards COVID-19. There is a need to follow the preventive protocols and dissemination of correct information through conducting educational interventions that target safe health practices and provide appropriate information on this infection.


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