Abstract 207: Dissemination of Hands-Only Cardiopulmonary Resuscitation and the Impact on the Outcome in School Students and Young Adults After Out-of-Hospital Cardiac Arrest of Presumed Cardiac Origin: A Japanese Nationwide Utstein Registry Study

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Yoshihide Mitani ◽  
Noriko Yodoya ◽  
Hiroyuki Ohashi ◽  
Hirofumi Sawada ◽  
Masahiro Hirayama

Introduction: Out-of-hospital cardiac arrests (OHCA) of presumed cardiac origin witnessed by nonfamily members in the daytime are most effectively resuscitated in the youth, in which the impact of recently disseminated hands-only cardiopulmonary resuscitation (CPR) is poorly understood. Hypothesis: Dissemination of hands-only CPR is associated with the better outcome in school students and young adults after such OHCA. Methods: We investigated OHCA of presumed cardiac origin in the youth (Group A, 7-12y; group B, 13-18y; group C, 19-22y; group D, 23-35y) which are witnessed by nonfamily members in the daytime (6:00-17:59) during 2005-15 by using Japanese nationwide Utstein registry. Results: We recruited 1,646 pts, in which N of pts was 92 (A), 382 (B), 229 (C) and 943 (D); ventricular fibrillation (VF) as the initial rhythm (%) was 48, 70, 64, and 59; bystander’s CPR (%) was 81, 80, 71 and 68; hands-only/bystander’s CPR (%) was 32, 38, 57, 56; bystander’s automated external defibrillator (AED) (%) was 37, 44, 24 and 19; the favorable neurological outcome at 1 month (CPC1-2)(%) was 46, 49, 39 and 30. Compared with group D, %bystander’s CPR (p=.013 in A, <.001 in B), %bystander’s AED (<.001 in both), and %CPC1-2 (.005, <.001) was higher but %hands-only CPR(<.001 in both) was lower in A and B, independent of the calendar year. Compared with 2005-09, %hands-only CPR, %bystander’s AED and CPC1-2 were higher in all age groups (<.005 in all) in 2010-15. In multivariate logistic analysis (gender, age groups (vs D), CPR type (conventional or hands-only CPR vs no CPR), bystander’s AED, the initial VF, emergency response time, calendar year), hands-only CPR (p=.03), bystander’s AED(<.001), female gender(.045), initial VF (<.001), emergency response time (<.001), and calendar year (<.001) were independently associated with CPC1-2. Conclusions: The present investigation demonstrates that resuscitation and outcome parameters after OHCA of presumed cardiac origin were persistently better in school students than young adults and that %hands-only CPR, which was persistently lower in school students, was independently associated with the better outcome in the youth overall. This finding may give a clue to further improvement of the outcomes in school students after OHCA.

2021 ◽  
pp. 1-11
Author(s):  
Stefano Orru’ ◽  
Kay Poetzsch ◽  
Marcus Hoffelner ◽  
Margarethe Heiden ◽  
Markus B. Funk ◽  
...  

<b><i>Introduction:</i></b> According to German legislation, reports of suspected serious adverse reactions (AR) associated with the donation of blood and its components are continuously being evaluated by the Paul-Ehrlich-Institut. This survey aimed at providing a more complete picture of the AR associated with the donation of blood and blood components. <b><i>Materials and Methods:</i></b> Eligible donors had the opportunity to anonymously report all AR occurring during or after their last donation by completing an online questionnaire. Reported AR were classified according to the Standard for Surveillance of Complications Related to Blood Donation. Donors’ self-assessment of AR seriousness was compared with the official severity classification as laid down by German legislation. Besides a descriptive statistical analysis, a multiple logistic analysis was performed to identify risk factors for AR. <b><i>Results:</i></b> A total of 8,138 data records were evaluated. Slightly more males (57.9%) participated in the survey and, except for donors aged ≥60 years, all age groups were equally represented. The majority of participants were whole blood donors (85.4%), repeat donors (97.2%), and stayed under observation in the blood establishment (BE) for more than 5 min (63.1%) after donation. Most participants did not report any reaction (72.5%), whereas 2,237 reported at least one AR (27.5%), 475 of whom underwent apheresis and 1,762 donated whole blood. Most AR occurred after leaving the BE (64.4%). Only a minority of participants required medical treatment (5.1%) or assessed the experienced AR as serious (3.9%). The most frequently reported donor AR were haematoma and other local reactions (57.6%). Vasovagal reactions without and with loss of consciousness were developed in 17 and 2% of the participants, respectively, whilst 7.6% experienced citrate reactions. New AR (i.e., allergic reactions and symptoms associated with iron deficiency) were reported as well. The occurrence of AR was linked to risk factors (i.e., female gender, young age, first-time donation, and thrombocytapheresis). <b><i>Discussion:</i></b> This survey yielded a more comprehensive AR spectrum, revealed a prolonged time to symptom onset, and identified risk factors for AR. This novel information could be implemented in an amended informed consent addressing common and rare AR.


BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e027233 ◽  
Author(s):  
Helen S Marshall ◽  
Mark McMillan ◽  
Ann Koehler ◽  
Andrew Lawrence ◽  
Jenny MacLennan ◽  
...  

IntroductionInvasive meningococcal disease is uncommon but associated with a high-case fatality rate. Carriage prevalence of the causative bacteria,Neisseria meningitidis, is high in adolescents. A large (n=34 500) cluster randomised controlled trial (RCT) to assess the impact of a meningococcal B (MenB) vaccine on meningococcal carriage was implemented in the state of South Australia (SA) for year 10, 11 and 12 senior school students in 2017–2018. This study will assess the impact of MenB vaccine (4CMenB) on carriage prevalence in school leavers in SA, 1 and 2 years after implementation of the cluster RCT in adolescents. Measuring the impact of population programmes on carriage can assist in informing future meningococcal immunisation programmes such as targeted age groups and use of catch-up campaigns.Methods and analysisThis repeat cross-sectional study will assess carriage prevalence in 2018 and 2019. All school leavers who attended year 12 in any school in SA in 2018 or 2019 will be invited to participate in this study. An oropharyngeal swab will be taken from each participating student and a risk factor questionnaire completed by the student following informed consent. Students will attend clinics at SA universities, technical colleges, and metropolitan, rural and remote government council clinics. Confirmed vaccination history will allow a comparison in carriage prevalence between vaccinated and unvaccinated school leavers. A sample size of 4096 students per year will provide 80% power to detect a 20% difference in carriage prevalence of disease-causing meningococci (defined as genogroup A, B, C, W, X or Y) between years.Ethics and disseminationThe study was approved by the Women’s and Children’s Health Network Human Research Ethics Committee. Results will be published in international peer review journals and presented at national and international conferences.Trial registration numberNCT03419533; Pre-results


2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Aladine A Elsamadicy ◽  
Andrew B Koo ◽  
Wyatt B David ◽  
Victor Lee ◽  
Cheryl K Zogg ◽  
...  

Abstract Background Mounting evidence supports the presence of heterogeneity in the presentation of ependymoma patients with respect to location, histopathology, and behavior between pediatric and adult patients. However, the influence of age on treatment outcomes in ependymoma remains obscure. Methods The SEER database years 1975–2016 were queried. Patients with a diagnosis of ependymoma were identified using the International Classification of Diseases for Oncology, Third Edition, coding system. Patients were classified into one of 4 age groups: children (age 0–12 years), adolescents (age 13–21 years), young adults (age 22–45 years), and older adults (age &gt;45 years). The weighed multivariate analysis assessed the impact of age on survival outcomes following surgical treatment. Results There were a total of 6076 patients identified with ependymoma, of which 1111 (18%) were children, 529 (9%) were adolescents, 2039 (34%) were young adults, and 2397 (40%) were older adults. There were statistically significant differences between cohorts with respect to race (P &lt; .001), anatomical location (P &lt; .001), extent of resection (P &lt; .001), radiation use (P &lt; .001), tumor grade (P &lt; .001), histological classification (P &lt; .001), and all-cause mortality (P &lt; .001). There was no significant difference between cohorts with respect to gender (P = .103). On multivariate logistic regression, factors associated with all-cause mortality rates included males (vs females), supratentorial location (vs spinal cord tumors), and radiation treatment (vs no radiation). Conclusions Our study using the SEER database demonstrates the various demographic and treatment risk factors that are associated with increased rates of all-cause mortality between the pediatric and adult populations following a diagnosis of ependymoma.


Author(s):  
Rosa M Sánchez-Casas ◽  
Ildefonso Fernández-Salas ◽  
Maricela Laguna-Aguilar ◽  
Jorge J Rodríguez-Rojas ◽  
Marcia L Medina-Ponce ◽  
...  

SUMMARY The prevalence of pediculosis in Mexican children was studied in San Nicolas and Tapachula, Mexico. A cross-sectional study included 888 students between six and 12 years old from two urban communities with an unequal socioeconomic status between September 2015 and March 2016. A Pearson χ2 and multivariate logistic analysis were carried out to associate risk factors to pediculosis. The overall prevalence of pediculosis from both localities was 23.9%. The female gender; long and medium hair; living with someone infested; previously infested by head lice and curling hair were variables linked to a significantly higher prevalence of pediculosis (p &lt; 0.01). Nevertheless, no significant differences were observed in the age groups, localities and socioeconomic status for human lice infection. Socioeconomic variables such as numbers of inhabitants, floors of house, beds and rooms; and parents’ qualification did not show a significative association for pediculosis. Health education in schools is needed for pediculosis prevention and remove the stigmatization of this disease related to poverty.


2018 ◽  
Vol 15 (4) ◽  
pp. 2462
Author(s):  
Nuh Osman Yıldız ◽  
Güçlü Özen ◽  
Ahmet Özsoy

The aim of this research is to determine the effects of artificial wall climbing - which was performed by primary school students- as a recreative activity on children’s locus of control. Artificial wall climbing represents itself as a learning point beyond a sportive activity while creating an opportunity for participants to discover the limits of their own and that of others’, and opening a path for learning through experience by rendering the participants active rather than passive.The research was designed as one group pre-test – post-test model. The sample of the study is the same as the study population. 40 (15 female, 25 male) students studying in 7th and 8th grades of primary school attended voluntarily in this study.  Climbing practices were determined according to students' free time. Climbing practices were planned to be 90 minutes each. It is organized two days in a week between at least twenty-four hours. The test lasted 6 weeks in total. The activity which started with warm-up exercises suited for the age group was configured as a developmental schema as it started with top rope and extended to lead climbing route again on the climbing routes suited for the age groups. During the practice, it was ensured to provide knowledge and skills for not only climbing skills but also for other topics such as basic knowledge of climbing techniques, basic knots and belaying. The practice lasted six weeks and the questionnaire was applied before and after.To determine whether participants had a tendency towards externalizing or internalizing bias, "Nowicki-Strickland Locus of Control Scale" was used.As a result of the statistical analysis, it was observed that there are significant differences between pre-test and the difference of differences regarding the gender discrepancy and between pre-test and post-test scores regarding the total scores (p<0.05).The group of activities carried out for the artificial wall climbing led to a positive development in the children’s perception of locus of control and it was seen that children's beliefs on what’s happening around them is under their control and they can turn their lives in whichever direction they want were positively influenced.


2005 ◽  
Vol 27 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Clarissa Marceli Trentini ◽  
Flávio Merino de Freitas Xavier ◽  
Eduardo Chachamovich ◽  
Neusa Sica da Rocha ◽  
Vânia N Hirakata ◽  
...  

BACKGROUND: The Beck Depression Inventory (BDI) has been widely used to assess the prevalence of depressive symptomatology in clinical and non-clinical samples. On elders, however, the Beck Depression Inventory total score can be influenced by the increased scores on somatic and performance subscale due to the impact of ageing process itself and clinical diseases. PURPOSE: To verify if there are differences between answers of adults and elders for the BDI Somatic and Performance subscale. METHODS: Five hundred and fifty six subjects were interviewed. Two hundred and seventeen were adults (between 18 and 59 years old) and 339 were elders (> 60 years). Adults and elders with terminal diseases or dementia were excluded. The convenience sampling method was used. RESULTS: Elders answered significantly with higher scores in the Somatic and Performance subscale compared to adults (p < 0.001). Female gender and educational level were also associated to higher scores in the Somatic subscale. No differences between both age groups were found in the Cognitive-Affective subscale (p = 0.332). CONCLUSIONS: Positive answers in the BDI Somatic and Performance subscale must be carefully assessed among elder subjects. The age factor, either by aging or due to several diseases, can bring signs that are not necessarily symptoms of major depression. Further studies are suggested.


Angiology ◽  
2020 ◽  
pp. 000331972096194
Author(s):  
Kuljit Singh ◽  
Rosanna Tavella ◽  
Tracy Air ◽  
Matthew Worthley ◽  
Ajay Sinhal ◽  
...  

The differential impact of young age and female gender on transradial access (TRA) outcomes remains to be confirmed. The primary objective was to assess the impact of young age and female gender on in-hospital net adverse cardiovascular events (NACE). Among 12 346 patients from the Coronary Angiogram Database of South Australia (CADOSA) Registry, the impact of gender; men (transfemoral access [TFA] 1995, TRA 6168) and women (TFA 1249, TRA 2934), and a median split of age, ≤63 years (TFA 1617, TRA 4727) and >63 years (TFA 1627, TRA 4375) were analyzed on in-hospital outcomes by creating 5 separate propensity-matched cohorts (entire cohort, men, women, ≤63 and > 63 years). Net adverse cardiovascular event reduction with TRA was limited to the >63 years old cohort (odds ratio [OR] = 0.56, 95% CI: 0.34-0.93, P = .02) and women (OR = 0.37, 95% CI: 0.18-0.76, P = .007). In both the age groups and genders, TRA was associated with a lower risk of bleeding and all-cause mortality. On multivariate logistic regression, TRA was associated with a significant reduction in NACE, major bleeding, and mortality in the overall cohort. In conclusion, a reduction in bleeding and mortality was noted with TRA in all the subgroups in this observational study.


PEDIATRICS ◽  
1993 ◽  
Vol 91 (1) ◽  
pp. 158-159
Author(s):  

The American Academy of Pediatrics recommends that high school students receive training in Basic Life Support (BLS) and Pediatric Basic Life Support (PBLS) as part of their health education program. The skills taught, such as recognition of symptoms, establishment of an airway, and rescue breathing, will help prepare students to deal with individuals who need their assistance due to aspiration or cardiorespiratory emergencies. Individual efforts using only BLS/PBLS skills can be effective in rescuing patients in these circumstances.1-3 Prompt initiation of cardiopulmonary resuscitation (CPR) after early recognition of a cardiac arrest has limited success alone. This education must be supported by a community emergency response system. Immediate CPR coupled with access to the community emergency response team maximizes the impact of school education programs.4,5 School-based programs have been successful in training students to have BLS skills.6,7 The Academy does not expect that BLS/PBLS training will prepare students for all emergencies, nor does it intend that students should be made to believe they are solely responsible for rescuing victims or for the survival of individuals with life-threatening events in their school or community. Younger students should be reassured that their responsibility is limited during emergency events, particularly when adults are available. In addition to the potential benefits of BLS/PBLS, a realistic perspective of resuscitation abilities as only a link in the "chain of survival" should be provided. The limitations of BLS/PBLS and of all emergency services on the eventual outcome of cardiac arrests also should be explained.8 Students should be given information about avoiding the acquisition of transmissible diseases during CPR.


Medicina ◽  
2019 ◽  
Vol 55 (3) ◽  
pp. 75 ◽  
Author(s):  
Jurgita Gailite ◽  
Dana Apela ◽  
Iveta Dzīvīte-Krišāne ◽  
Dace Gardovska

Background and objectives: The efficacy of a weight correction programme can be affected by such predictors as the number of contact hours, gender, age, baseline weight, parental weight status, psycho-emotional status, insulin resistance, and socioeconomic status. The aim of this current study was to evaluate the overall efficacy of the Weight Correction Programme at Children’s Clinical University Hospital, and explore the impact of the probable predictors. We evaluated the efficacy depending on gender, age, parental weight status, signs of depression, baseline body mass index z-score (z-BMI), and baseline waist circumference. Materials and Methods: The data were gathered from medical records. The inclusion criteria were as follows: Entered the programme by 13 June 2017, at least five years old, follow-up data available. All the respondents were divided into two age groups: <10 years old and ≥10 years old. Results: The study included 181 respondents. They were 5 to 17 years old on the first day of participation in the Weight Correction Programme. Results indicated that 117 (65%) patients managed to reduce z-BMI and 69 (38%) patients achieved clinically significant reduction of z-BMI. Boys had four times higher odds (odds ratio (OR) = 4,22; CI 1.37–13.05; p = 0.012) to reduce their z-BMI by at least 0.20 units than girls. The respondents of the older age group (≥10 years) had a better chance to reduce z-BMI than the younger ones (OR = 11,51; CI 2.04–64.83; p = 0.006). The odds to reduce z-BMI were lower by 7% for every extra cm of waist circumference (OR = 0.93; CI 0.88–0.99; p = 0.014) for reducing z-BMI. The follow-up time was also a positive predictor, and with every month the odds for clinically significant z-BMI reduction increased by 7% (OR = 1.07; CI 1.00–1.15; p = 0.047). The parental weight status, signs of depression, and baseline z-BMI were not significant predictors. Conclusions: More than half of the patients of the respondents managed to reduce their z-BMI. Female gender, younger age, and larger waist circumference were negative predictors.


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