scholarly journals КІРЛІАНОГРАФІЧНЕ ОЦІНЮВАННЯ БІОДОСТУПНОСТІ РЕЧОВИНИ

Author(s):  
M. V. Kuryk ◽  
L. A. Pesotska ◽  
N. V. Hlukhova ◽  
А. I. Horova

<p class="a0">The ratio between water molecules associated to the clusters in cell structures, which is the conformational catalyst for the exchange processes, and non-associated or free water participating in free-radical reactions is very important for the normal functioning of the organs of living beings.</p><p class="a0">The aim of the study was to compare Kirlian glow of apple samples before and after t h e sanctification during the Christian holiday The Saviour to detect the possibility of the bioavailability signs establishing of the product for the body.</p><p class="a0">The kirlianographic study of 10 samples of whole and cut apples with the same sort and size before and after the sanctification was made. Radiographic film and standard methods of its development as well as the instrument “REK-1”, designed by Ukrainian Research Institute of Machine Building Technology (D nepropetrovsk) were used. Mathematical processing of scanned Kirlianograms was performed using standard software package for th e construction of histograms and pixel brightness profile of the picture.</p><p class="a0">The method of classical kirlianography with X ray film allows assessing the bioavailability condition, which is important for the prediction of absorption and physiological effects of a man consumed food and phytomedicines. Therefore, these studies are relevant and require further development. Used such standard methods of mathematical processing as histograms and pixel brightness profile for the analysis of Kirlian images are informative enough for the individual samples, and can be the basis for the batch processing of data.</p>

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Weiwei Lin

Objective (1)Through the blood physiological and biochemical tests during the altitude training, to analyze the body function of swimmers in this stage.(2) Through the individual lactate threshold tests before and after the altitude training,to analyze the effects of altitude training. Methods Eight swimmers took a 26-day altitude training session.The individual lactate threshold test was carried out by the Swedish Monak839E power cycle progressive loading method before and after the training;During the altitude training period, 5ml of the subjects' elbow vein was extracted and tested on an empty stomach and in a quiet state every Monday morning. Results (1)When swimmers reached the plateau, the hemoglobin value was indistinguishable from the plain(male 156.2±7.01,female 135.7±8.75g/L),From the hemoglobin value (male 154.03 + 5.67, female 134.23 + 9.66g/L), there was a decrease in both male and female in the second week.But hypoxia stimulated red blood cell production, and the body itself was gradually adapting to the training load.Thus, the hemoglobin value of the third week (male 157.17 + 3.7, female 141.93 + 10.06g/L) was significantly improved, and higher than the level of the first week.During the altitude training period, the mean value of male’s blood testosterone was 474.33 + 97.06ng/dl, and the female’s blood testosterone was 33.67 + 17.25ng/dl.Male’s blood testosterone was lower than the mean of the national team, because the study participants were youngers who were not fully developed and had shorter training years.There were different trends in blood testosterone value between male and female. Male’s blood testosterone values during the Monday morning of these three weeks were 479.67±76.25、492.33±83.61、451±153.41ng/dl respectively.female’s blood testosterone values during the Monday morning of these three weeks were 29.33±21.83、32±23.26、39.67±9.29ng/dl respectively.These further indicated that this altitude training plan was more suitable for male with shorter training years, and the body had certain fatigue accumulation, but the decrease range was within a reasonable range.However, the increase of blood testosterone per week in female indicated that the training stimulation depth was not enough, and the potential of athletes should be further explored.According to the changes of creatine kinase, the sensitivity of male to the change of altitude training intensity was also shown, and the highest value of creatine kinase was 731U/L in the first week.(2) From the value of the individual lactate threshold before and after altitude training, no matter male or female,the change was not obvious, but was generally improved, this may be the altitude training adopted the pattern of three and a half weeks, training time was short.Secondly, as a professional athlete, the "plastic space" gradually decreased with the extension of the training years.Most of the peak blood lactate occurred in 1-3 minutes of recovery period.and the average value increased from 8.96 + 1.86mmol/L before altitude training to 9.99 + 1.47mmol/L.Among them, the peak value of male’s blood lactate was increased from 8 + 2.22mmol/L before the altitude training to 10.91 + 1.43mmol/L, and there was a significant difference in the peak of blood lactate before and after the altitude training.However, the peak value of female’s blood lactate was decreased from 9.92 + 0.79mmol/L before the altitude training to 9.07 + 0.88mmol/L. This was mainly due to the fact that a member of the swimmers had caused the result, and this swimmer’s enduring lactate level was lower than the one before the plateau. Conclusions The altitude training generally improved athletes’ training ability, but based on factors such as training age, gender, should be targeted according to the individual situation of each athlete training plan, so as to achieve more from less.


1988 ◽  
Vol 65 (1) ◽  
pp. 318-324 ◽  
Author(s):  
H. Nose ◽  
G. W. Mack ◽  
X. R. Shi ◽  
E. R. Nadel

To investigate the influence of [Na+] in sweat on the distribution of body water during dehydration, we studied 10 volunteer subjects who exercised (40% of maximal aerobic power) in the heat [36 degrees C, less than 30% relative humidity (rh)] for 90-110 min to produce a dehydration of 2.3% body wt (delta TW). After dehydration, the subjects rested for 1 h in a thermoneutral environment (28 degrees C, less than 30% rh), after which time the changes in the body fluid compartments were assessed. We measured plasma volume, plasma osmolality, and [Na+], [K+], and [Cl-] in plasma, together with sweat and urine volumes and their ionic concentrations before and after dehydration. The change in the extracellular fluid space (delta ECF) was estimated from chloride distribution and the change in the intracellular fluid space (delta ICF) was calculated by subtracting delta ECF from delta TW. The decrease in the ICF space was correlated with the increase in plasma osmolality (r = -0.74, P less than 0.02). The increase in plasma osmolality was a function of the loss of free water (delta FW), estimated from the equation delta FW = delta TW - (loss of osmotically active substance in sweat and urine)/(control plasma osmolality) (r = -0.79, P less than 0.01). Free water loss, which is analogous to "free water clearance" in renal function, showed a strongly inverse correlation with [Na+] in sweat (r = -0.97, P less than 0.001). Fluid movement out of the ICF space attenuated the decrease in the ECF space.(ABSTRACT TRUNCATED AT 250 WORDS)


2020 ◽  
Vol 6 (2) ◽  
pp. 47-54
Author(s):  
E. Petrenko

The article discusses the main provisions of the book, in which its author described the development of man with certain differences from the ideas existing in universities on this problem, which arose as a result of his many years of research, analysis of his own and literary data. Human development at different stages, before and after birth, the author studied on the basis of taking into account the close relationship of all parts of the body of the individual, all his organs, such important features of his development as uneven growth rates and directions of organs and asynchronous during ontogenesis development of different emerging organ systems. The greatest novelty of such a representation in the book under discussion concerns the digestive, venous and lymphatic systems, the development of which the author has investigated to the greatest extent, although he has conducted other studies


Author(s):  
S.K. Aggarwal ◽  
J.M. Fadool

Cisplatin (CDDP) a potent antitumor agent suffers from severe toxic side effects with nephrotoxicity being the major dose-limiting factor, The primary mechanism of its action has been proposed to be through its cross-linking DNA strands. It has also been shown to inactivate various transport enzymes and induce hypocalcemia and hypomagnesemia that may be the underlying cause for some of its toxicities. The present is an effort to study its influence on the parathyroid gland for any hormonal changes that control calcium levels in the body.Male Swiss Wistar rats (Crl: (WI) BR) weighing 200-300 g and of 60 days in age were injected (ip) with cisplatin (7mg/kg in normal saline). The controls received saline injections only. The animals were injected (iv) with calcium (0.5 ml of 10% calcium gluconate/day) and were killed by decapitation on day 1 through 5. Trunk blood was collected in heparinized tubes.


2001 ◽  
Vol 40 (01) ◽  
pp. 31-37 ◽  
Author(s):  
U. Wellner ◽  
E. Voth ◽  
H. Schicha ◽  
K. Weber

Summary Aim: The influence of physiological and pharmacological amounts of iodine on the uptake of radioiodine in the thyroid was examined in a 4-compartment model. This model allows equations to be derived describing the distribution of tracer iodine as a function of time. The aim of the study was to compare the predictions of the model with experimental data. Methods: Five euthyroid persons received stable iodine (200 μg, 10 mg). 1-123-uptake into the thyroid was measured with the Nal (Tl)-detector of a body counter under physiological conditions and after application of each dose of additional iodine. Actual measurements and predicted values were compared, taking into account the individual iodine supply as estimated from the thyroid uptake under physiological conditions and data from the literature. Results: Thyroid iodine uptake decreased from 80% under physiological conditions to 50% in individuals with very low iodine supply (15 μg/d) (n = 2). The uptake calculated from the model was 36%. Iodine uptake into the thyroid did not decrease in individuals with typical iodine supply, i.e. for Cologne 65-85 μg/d (n = 3). After application of 10 mg of stable iodine, uptake into the thyroid decreased in all individuals to about 5%, in accordance with the model calculations. Conclusion: Comparison of theoretical predictions with the measured values demonstrated that the model tested is well suited for describing the time course of iodine distribution and uptake within the body. It can now be used to study aspects of iodine metabolism relevant to the pharmacological administration of iodine which cannot be investigated experimentally in humans for ethical and technical reasons.


Author(s):  
A. E. Chernikova ◽  
Yu. P. Potekhina

Introduction. An osteopathic examination determines the rate, the amplitude and the strength of the main rhythms (cardiac, respiratory and cranial). However, there are relatively few studies in the available literature dedicated to the influence of osteopathic correction (OC) on the characteristics of these rhythms.Goal of research — to study the influence of OC on the rate characteristics of various rhythms of the human body.Materials and methods. 88 adult osteopathic patients aged from 18 to 81 years were examined, among them 30 men and 58 women. All patients received general osteopathic examination. The rate of the cranial rhythm (RCR), respiratory rate (RR) heart rate (HR), the mobility of the nervous processes (MNP) and the connective tissue mobility (CTM) were assessed before and after the OC session.Results. Since age varied greatly in the examined group, a correlation analysis of age-related changes of the assessed rhythms was carried out. Only the CTM correlated with age (r=–0,28; p<0,05) in a statistically significant way. The rank dispersion analysis of Kruskal–Wallis also showed statistically significant difference in this indicator in different age groups (p=0,043). With the increase of years, the CTM decreases gradually. After the OC, the CTM, increased in a statistically significant way (p<0,0001). The RCR varied from 5 to 12 cycles/min in the examined group, which corresponded to the norm. After the OC, the RCR has increased in a statistically significant way (p<0,0001), the MNP has also increased (p<0,0001). The initial heart rate in the subjects varied from 56 to 94 beats/min, and in 15 % it exceeded the norm. After the OC the heart rate corresponded to the norm in all patients. The heart rate and the respiratory rate significantly decreased after the OC (р<0,0001).Conclusion. The described biorhythm changes after the OC session may be indicative of the improvement of the nervous regulation, of the normalization of the autonomic balance, of the improvement of the biomechanical properties of body tissues and of the increase of their mobility. The assessed parameters can be measured quickly without any additional equipment and can be used in order to study the results of the OC.


Author(s):  
Paulina Hebisz ◽  
Rafal Hebisz ◽  
Marek Zaton

AbstractBackground: The purpose of this study was to compare body balance in road and off-road cyclists, immediately before and after the racing season.Material/Methods: Twenty individuals participated in the study and they were divided into two groups: specialists in road-cycling (n = 10) and in off-road cycling (n = 10). Immediately before and after the five-month racing season stabilographic trials were carried out (at rest and after progressive exercise). In assessing body balance the distance and velocity of the centre shifts (in the anterior-posterior and left-right direction) were analysed. The tests were performed with the cyclists’ eyes open, eyes closed, and in feedback.Results: After the racing season, in the off-road cyclists’ group, distance and velocity of the centre of pressure shifts increased after a progressive exercise.Conclusions: In the off-road cyclists’ group the balance of the body in the sagittal plane deteriorated after the racing season. Moreover, after the racing season off-road cyclists were characterized by a worse balance of the body, compared to road cyclists


2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Suaad Muhssen Ghazi ◽  
Fatin Shallal Farhan

Vitamin D deficiency is common in women with polycystic ovarian syndrome. Vitamin D plays an important physiologic role in reproductive functions of ovarian follicular development and luteinization through altering anti-müllerian hormone signaling, follicular stimulating hormone activity and progesterone production in human granulose cells. Vitamin D is precipitated in adipose fat tissues, making it notable to be used for the body as a result; obese people with high body mass index are already highly expected to have low levels of serum vitamin D.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1477-1481
Author(s):  
Ishwari Gaikwad ◽  
Priyanka Shelotkar

The current world situation is both frightening and alarming due to the massive disruption caused by the Covid-19 pandemic. The next few days are censorious as we need to be very precautious in our daily regimen as well as dietary habits. Ayurveda offers knowledge about food based on certain reasoning. Indecent food custom is the chief cause for the rising development of health disorders in the current era. In classical texts of Ayurveda, the concept of diet explained well, ranging from their natural sources, properties and specific utility in pathological as well as physiological manner. In this work, the review of the relevant literature of Ahara (Diet) was carried out from Charak Samhita and other texts, newspapers, articles, web page related to the same.  Every human being is unique with respect to his Prakriti (Physical and mental temperament), Agni (Digestive capacity), Koshtha  (Nature of bowel) etc. For that reason, the specificity of the individual should be kept in mind. Ahara, when consumed in the appropriate amount at the right moment following all Niyamas (Guidelines) given in Ayurveda texts, gives immunity and keeps the body in a healthy state during pandemics such as Covid-19. Ultimately, this will help the human body to maintain its strength for life. This article reviews the concept of diet viz. combination of foods, their quantity and quality, methods of preparation and processing, which are to be followed during pandemics and are essential in maintenance and endorsement of health and preclusion of diseases.


2020 ◽  
Vol 5 (5) ◽  
pp. 386-393
Author(s):  
L. M. Gunina ◽  
◽  
Kazys Mylashyus ◽  
Voitenko V. L. ◽  
◽  
...  

Under high-intensity loads, the athlete's bodies take place a number of biochemical reactions and physiological processes that can lead to hyperbilirubinemia. The factors that can initiate the onset of this phenomenon include the syndrome of micro-damage muscle, violation of the integrity of erythrocyte membranes, decreased blood pH, malnutrition and increase oxygen demand of the body. Degree of expression of manifestations of physiological bilirubinemia depends on the level of adaptation of the athlete to the physical activities offered. Hyperbilirubinemia in athletes can be one of the components of the deterioration of the functional state, forming the symptoms of endogenous intoxication. The relevance of this problem in sport lies in the relatively low detection rate of hyperbilirubinemia due to the lack of regular screening studies. However, in drawing up a plan of nutritional- metabolic support for training and competitive activity and recovery measures, must not only the individual reaction of the athlete body to physical activity, but also the severity of shifts in the indicators of bilirubin metabolism and their ratio. The article describes the reasons for the increase in bilirubin levels, which can be caused by both the effect of physical activity and by the presence of pathological processes in athletes. The factors influencing the blood serum’s bilirubin content are also highlighted, which include the state of erythrocyte cell membranes and the rate of hemoglobin destruction, the functional state of the liver, the specifics of physical loads and the use of ergogenic pharmacological agents by athletes. Particular accent has been placed on the illumination of hereditary hyperbilirubinemias, which may have been detected at the stage of selection of athletes. The most common phenomenon is Gilbert's syndrome, which occurs in 2-5% of cases in the general population, is characterized in the clinic by a benign flow and is manifested by episodes of jaundice and an increase in total bilirubin content to moderate values due to indirect. The frequency of detection of hyperbilirubinemias in the population of athletes is 4.68%, among which Gilbert's disease accounts for almost half (48.7%). Conclusion. The work highlighted the pathogenesis and diagnostic algorithm of Gilbert's disease, and also emphasized that its drug prevention and correction in athletes to maintain functional and physical fitness should be carried out taking into account anti-doping rules, which requires upon diagnosis timely receipt of a therapeutic exclusion


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