Abstract P267: Does Admission for Transient Ischemic Attack Lead to Differences in 1-Year Outcomes?

Author(s):  
Eric Cheng ◽  
Michael Cline ◽  
Joshua Robinson ◽  
Laura Myers ◽  
Flossy Lincoln ◽  
...  

Background: A new transient ischemic attack (TIA) is a risk factor for a future vascular event. Reducing that risk requires a timely diagnostic workup and delivering secondary stroke preventive services. It is unknown whether such care should be performed in the inpatient or outpatient setting. Methods: Using administrative databases, we identified all veterans with a diagnosis code for TIA assigned in the emergency department or urgent care setting in the Veterans Health Administration during fiscal year 2008. We calculated the proportion who were admitted and predictors of admission. At one-year after presentation of TIA, we examined the proportion who were assigned a new diagnosis code for stroke, myocardial infarction, or death. We then determined whether admission was associated with outcomes using chi-square and multivariate logistic models. Results: The sample consisted of 2247 persons with a new diagnosis of TIA, and 35% were admitted within one day of presentation. The mean age was 68, and 25% had a prior history of stroke or TIA. At one-year, 12.1% developed the composite outcome of stroke, myocardial infarction, and death. Older age, history of hypertension, atrial fibrillation, and diabetes were associated with admission (p<0.05). In unadjusted analyses, the composite outcome was not significantly different among persons admitted vs. not admitted (13.1% vs. 11.6%, p=0.29). In multivariate analyses, admission was not significantly associated with the composite outcome (see Table ). Discussion: Persons admitted for TIA are more likely to possess stroke risk factors than those who were not admitted. The decision to admit was not associated with differences in one-year outcomes. Ongoing work will compare the completeness and timeliness of the diagnostic work-up of TIA as well as long-term control of stroke risk factors among persons admitted versus persons not admitted. Predictors of 1-year stroke, myocardial infarction, or death among persons with TIA Odds ratio [95% CI] p-value Hospital admission within one day 1.0 [0.8 - 1.4] 0.7 Age 1.0 [1.0 -1.0] <0.001 History of hypertension 1.2 [0.9 - 1.7] 0.2 History of atrial fibrillation 1.5 [1.1 - 2.0] <0.05 History of diabetes 1.2 [0.9 - 1.5] 0.3 History of stroke 1.8 [1.3 - 2.5] <0.001 History of TIA 0.7 [0.5 - 1.1] 0.1 History of myocardial infarction 2.9 [1.3 - 6.1] <0.01

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Dawn M Aycock ◽  
Kenya D Kirkendoll ◽  
Kisha C Coleman ◽  
Karen C Albright ◽  
Anne W Alexandrov

Background & Purpose: Young to middle aged African Americans (AA) are at greater risk for a first-ever stroke, severe neurologic disability, and stroke-related mortality, than Caucasians of similar age; however, it remains unclear what role a family history of stroke (FHS) plays in promoting adoption of healthier lifestyles in this cohort. The purpose of this study was to explore differences between rural Stroke Belt AA with a FHS (e.g. parent/grandparent/sibling) on modifiable stroke risk factors, knowledge, perceived threat and perceived control of stroke, and exercise behaviors to AA without a FHS. Methods: A cross-sectional study was conducted recruiting AA aged 19-54 from the Black Belt region of Alabama via a mobile health clinic. Participants’ perceptions, knowledge, exercise history/intent, physiologic data, and health history were recorded. Results: Participants (N=66) averaged 43.3+9.4 years, were 71% female, with at least 12 years of school (89%), and unemployed (62%). Common risk factors were insufficient exercise (76%), obesity (59%), hypertension (53%; blood pressure M=145+17.6/88.3+12.9), and cigarette smoking (38%). Participants with a FHS (n=33) did not differ on average number of risk factors compared to those without a FHS (FHS 2.8+1.4 vs. 2.2+1.5; t(64)= 1.73, p=.089), nor did they differ on physiologic data. However, participants with a FHS were more likely to report a history of hypertension (67%) compared to those without a FHS (33%; χ2 =4.93, p <.05). There were no significant differences between groups for knowledge of stroke risk factors, perceived threat and perceived control of stroke, or recent exercise performance, although participants with a FHS (3.4+1.2) had significantly lower future intentions to exercise compared to those without a FHS (3.9+0.8); t(64)=2.45, p<.05). Conclusions: Although FHS is a significant non-modifiable risk factor for stroke and was common in this young to middle-aged AA cohort, FHS did not drive perceived stroke risk, risk factor control, or current/future intentions to exercise. Identification of interventions designed to personalize FHS as a key stroke risk factor, while promoting lifestyle change and self-management, may play an important role in future primary stroke prevention.


2017 ◽  
Vol 23 (5) ◽  
pp. 4429-4433
Author(s):  
Muhammad Hazrani Abdul Halim ◽  
Yumn Suhaylah Yusoff ◽  
Mazlynda Md Yusuf

2019 ◽  
Vol 4 (7) ◽  

Introduction: Patients undergoing hemodialysis are at increased risk of stroke. However, less known about the impact of some of the stroke risk factors, and the value of stroke risk scores in determining the risk in those patients. Our main goal. To assess the risk factors for stroke in hemodialysis patients and the use of the new CHA2DS2-VASc score for stroke assessment. Methods: Single center, retrospective cohort study of 336 patients undergoing hemodialysis from June 24, 2018, to September 6, 2018, was recruited. Baseline demographics, clinical, and laboratory data were collected. We calculated the CHA2 DS2 -VASc score for stroke assessment in all patients and categorized them into high, moderate and low risk patients according to CHA2 DS2 - VASc score and subcategorized them to two groups atrial fibrillation (AFib) and Non- Atrial fibrillation (Non AFib) patients. Results: 336 patients were included in our study; the majority of patients were at high risk with a CHA2 DS2 -VASc Score mean of 2.9± 1.5, although history of stroke was observed only in 15 patients (4.46%). According to CHA2 DS2 - VASc score, 280 patients were at high risk, 172 (51.19%) were high-risk patients on treatment (anticoagulant or antiplatelet) and 108(32.14%) patients were high risk patients not on treatment 48 were at moderate risk (14.28%) and 8 were at low risk (2.38 %). Patients were divided into subgroups as non-AFib and AFib. In non-AFib patients 320 (95.23%), high-risk patients 103 (32.18%) were not treated; high-risk patients with treatment are 162 (50.62%), moderate patients were 47 (14.68%), 8(2.5%) was in low risk. AFib patients were 16 with a mean CHA2 DS2 -VASc score of 4.4±1.1. Patients with AFib were all at high risk except 1 was at moderate risk (6.25%). There were 11 (68.75%) patients on treatment and 5 (31.25%) patients not on treatment. The risk factors for stroke that were statistically significant in increasing score risk for all patients were: age > 65 (95% CI, -2.04– -1.29; p = 0.000), being female (95% CI, -1.36– -0.68; p = 0.000) hypertension (95% CI, -2.59– -1.37; p = 0.000), diabetes (95% CI, -2.10– -1.50; p = 0.000), CVD (95% CI, -2.07– -1.24; p=0.000), history of stroke or TIA (95% CI, -3.70– -2.03; p = 0.000), CHF or LVEF (95% CI, -2.28– - 0.91; p = 0.000). Conclusions: The risk of stroke in hemodialysis patients is significant according to the use of CHA2 DS2 -VASc score in Non-AFib hemodialysis patients shows supportive evidence of increased risk of stroke in those patients, which suggest the importance of close monitoring of patients with stroke risk factors by the nephrologist and the stroke team which will lead to the initiation of early prophylaxis in those patients.


e-CliniC ◽  
2014 ◽  
Vol 2 (3) ◽  
Author(s):  
Rio Christanto ◽  
Corry N. Mahama ◽  
Melke J. Tumboimbela

Abstract: Stroke is a serious neurological disease, with acute attacks that can lead to death. Closely related to the occurrence of stroke risk factors possessed by the patient, especially if there are risk factors that are not addressed properly. Aim: To know the profile of risk factors in stroke patients hospitalized in neurology. irina F  of  RSUP Prof. Dr. R. D. Kandou Manado among period january to october 2012. Methods: The study descriptive with retrospective method is to collect all the data of patients who had been diagnosed with stroke in inpatient neurology irina F RSUP Prof. Dr. R. D. Kandou Manado among period january to october 2012. Results: The results showed that the highest percentage of stroke patients are in the age group 51-65 years (45.2%), male sex (51.2%), high risk category of hypertension (92.2%), risk category Low dyslipidemia ((73.1%), low risk of diabetes mellitus (83.8%), history of heart problems (40.2%), had a history of smoking (8.2%). Conclusion: There are three factors that influence the risk of stroke incidence is age, gender and hypertension Keywords: stroke, risk factors Abstrak: Stroke merupakan penyakit neurologi yang serius, dengan serangan akut yang dapat menyebabkan kematian. Terjadinya stroke berkaitan erat dengan faktor risiko yang dipunyai oleh penderita, terutama bila faktor risiko yang ada tidak ditanggulangi dengan baik. Tujuan: Mengetahui profil faktor-faktor risiko pada pasien stroke yang di rawat inap di irina F neurologi RSUP Prof. Dr. R. D. Kandou Manado periode januari 2012 sampai oktober 2012. Metode: Penelitian deskriktif  dengan metode retrospektif yaitu mengumpulkan semua data penderita yang telah didiagnosa dengan stroke  yang di rawat inap di irina F neurologi RSUP Prof. Dr. R. D. Kandou Manado periode januari 2012 sampai Oktober 2012.  Hasil: Hasil penelitian menunjukan bahwa persentase terbanyak pasien stroke berada pada golongan umur 51-65 tahun (45,2%), berjenis kelamin laki-laki (51,2%), kategori risiko tinggi hipertensi (92,2%), kategori risiko rendah dislipidemia ((73,1%), risiko rendah diabetes melitus (83,8%), riwayat atau kelainan jantung (40,2%), memiliki riwayat merokok (8,2%). Simpulan: Terdapat 3 faktor risiko yang berpengaruh terhadap kejadian stroke yaitu umur, jenis kelamin dan hipertensi Kata kunci: Stroke, faktor risiko


2021 ◽  
Author(s):  
Chatpol Samuthpongtorn ◽  
Tul Jereerat ◽  
Nijasri Suwanwela

Abstract Background: Nowadays, the number of elderly has steadily increased annually. Elderly patients with ischemic stroke often have worse outcomes than younger patients. However, there has not been a study of ischemic stroke in the elderly in Thailand. A better knowledge of the risk factors, subtypes, and outcomes of strokes in the elderly may have significant practical implications for the aged society in the future. The objective of the study was to assess the risk factor, stroke subtypes, and outcome of stroke in the elderly compared to the younger patients.Method: All patients presented with acute ischemic stroke and transient ischemic attack (TIA) aged over 45 years who were admitted in the Stroke unit between November 1st, 2016 and December 31st, 2017 were retrospectively studied.Result: 542 patients were included. The average age was 68.78±12.03, 44.8% of them were male. 186 (34.3%) patients were 75 or older. Cardioembolism was found to be the most common cause of ischemic stroke in 156 patients (28.8%). Patients who were 75 or older had significantly worse outcomes in all categories including NIHSS at discharge, modified Rankin scale, length of stay and the number of deaths) compared to the younger group. Atrial fibrillation was the risk factors associated with older age with OR 3.861 (p value<0.001). Aged 75 years or older, atrial fibrillation, more NIHSS score on admission and history of the previous stroke were the risk factors associated with a patient's death.Conclusion: The elderly who are 75 years or older accounts for more than one-third of ischemic stroke in our study. Stroke in the elderly correlates with higher mortality and poorer outcome. Cardioembolism related to atrial fibrillation is the major cause of stroke in this population.


2015 ◽  
Vol 114 (10) ◽  
pp. 826-834 ◽  
Author(s):  
Flemming Skjøth ◽  
Peter Nielsen ◽  
Torben Bjerregaard Larsen ◽  
Gregory Lip

SummaryOral anticoagulation (OAC) to prevent stroke has to be balanced against the potential harm of serious bleeding, especially intracranial haemorrhage (ICH). We determined the net clinical benefit (NCB) balancing effectiveness and safety of no antithrombotic therapy, aspirin and warfarin in AF patients with none or one stroke risk factor. Using Danish registries, we determined NCB using various definitions intrinsic to our cohort (Danish weights at 1 and 5 year follow-up), with risk weights which were derived from the hazard ratio (HR) of death following an event, relative to HR of death after ischaemic stroke. When aspirin was compared to no treatment, NCB was neutral or negative for both risk strata. For warfarin vs no treatment, NCB using Danish weights was neutral where no risk factors were present and using five years follow-up. For one stroke risk factor, NCB was positive for warfarin vs no treatment, for one year and five year follow-up. For warfarin vs aspirin use in patients with no risk factors, NCB was positive with one year follow-up, but neutral with five year follow-up. With one risk factor, NCB was generally positive for warfarin vs aspirin. In conclusion, we show a positive overall advantage (i.e. positive NCB) of effective stroke prevention with OAC, compared to no therapy or aspirin with one additional stroke risk factor, using Danish weights. ‘Low risk’ AF patients with no additional stroke risk factors (i.e. CHA2DS2-VASc 0 in males, 1 in females) do not derive any advantage (neutral or negative NCB) with aspirin, nor with warfarin therapy in the long run.Note: The review process for this manuscript was fully handled by Christian Weber, Editor in Chief.


2020 ◽  
Vol 11 (1) ◽  
pp. 22-29
Author(s):  
Md Rashedul Islam ◽  
Tanbin Rahman ◽  
Rafi Nazrul Islam ◽  
Mohammad Sakhawat Hossen Khan ◽  
Mofizul Islam ◽  
...  

Background: Patients of stroke or transient ischaemic attacks (TIA) are at risk of further stroke. Our objective was to study patients admitted with stroke/TIA regarding their knowledge about risk factors for having anew event of stroke/TIA, possible associations between patient characteristics and patients’ knowledge about risk factors, and patients’ knowledge about their preventive treatment for stroke/TIA. Methods: A questionnaire was used for 200 patients with stroke/TIA diagnoses. We asked 13 questions about diseases/conditions and lifestyle factors known to be risk factors and four questions regarding other diseases/ conditions (“distractors”). Additional questions concerned with the patients’ social and functional status and their drug use were asked. Categorical variables were analyzed using chi square test, while one-way analysis of variance and univariate analysis of variance were used for continuous variables. Logistic regression was employed to describe risk. A p value of, p < 0.05 was considered statistically significant. Results: The risk factors that were most often identified by the patients were Diabetes(75.9%), hypertension(83.3%), previous stroke or TIA(81.5%), smoking (85.2%), regular exercise(75.9%), older age(83.3%), overweight (75.9%) and patients with ischemic heart disease (70.4%). Atrial fibrillation and carotid stenosis were identified by less than 50% of the patients. 44.5% of the patients could identify 10 or more stroke/TIA risk factors. We observed that higher age, having a diagnosis of cerebral infarction/TIA, patients residing in urban area, high income group, businessman/retired service holder, family history of cardiovascular disease, past history of stroke / TIA were related to better knowledge of stroke/TIA risk factors. Anticoagulants and antiplatelets are important drugs for stroke/TIA prevention but only 20(9.3%) of the patients who reported anticoagulants and 76(35.2%) of the patients taking these drugs marked them as intended for prevention. Conclusion: Knowledge about diabetes, hypertension and smoking as risk factors was good, and patients who suffered from atrial fibrillation or carotid stenosis seemed to be less informed about these conditions as risk factors. The knowledge level was low regarding the use of anticoagulants and antiplatelets for stroke/TIA prevention. Better patient educational strategies for stroke/TIA patients should be developed. Furthermore, individuals with less knowledge should be given special consideration when developing strategies and programmes thus improving awareness of stroke risk factors. Birdem Med J 2021; 11(1): 22-29


Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. P01.008-P01.008
Author(s):  
F. Babtain ◽  
M. Al Hamrany ◽  
A. Al Hazzani ◽  
E. Al Shehri ◽  
B. Al Ghamdi ◽  
...  

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