The association between alcohol use disorder and suicidal ideation in a New Zealand birth cohort

Background: Alcohol use disorder is associated with increased suicide risk; however, both alcohol use disorder and suicide share risk factors which must be accounted for in order to understand this relationship. This study aimed to explore the longitudinal relationship between alcohol use disorder and suicidal ideation in adulthood, while accounting for both child background and adult covariate factors. Method: Data were collected from the Christchurch Health and Development Study, a birth cohort of 1265 children born in Christchurch (New Zealand) in mid-1977. Alcohol use disorder (operationalised as alcohol abuse and alcohol dependence) was quantified between age 18 and 40 in five data waves. The outcome measure suicidal ideation was reported over the same time periods. Childhood confounding variables were controlled for, as well as time-dynamic covariates collected in adulthood, including internalising disorders, distress due to relationship dissolutions and other substance use disorders. Results: The association between alcohol abuse and suicidal ideation was not statistically significant before or after adjusting for childhood confounding and adulthood covariate factors, when compared to no alcohol disorder. However, the association between alcohol dependence and suicidal ideation was significant both before and after adjustment (unadjusted odds ratio = 2.89, 95% confidence interval = [2.09, 3.99]; adjusted odds ratio = 1.52, 95% confidence interval = [1.04, 2.23]), when compared to no alcohol disorder. Furthermore, alcohol dependence remained significant when compared to alcohol abuse (unadjusted odds ratio = 2.33, 95% confidence interval = [1.61, 3.37]; adjusted odds ratio = 1.54, 95% confidence interval = [1.00, 2.37]). Conclusion: This analysis found an association between alcohol dependence and suicidal ideation within a New Zealand birth cohort, which persists even after adjustment for childhood confounding and adulthood covariate factors. Given the high rates of suicide and heavy drinking within the New Zealand population, any comprehensive national or regional suicide prevention plan should seek to reduce risky alcohol consumption at an individual and population level, as this represents a modifiable risk factor for suicide.

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Evaluation of childhood traumatic experience as a risk factor for alcohol use disorder in adulthood

BMC Psychiatry ◽

10.1186/s12888-020-2428-5 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Lan Wang ◽

Cui-Xia An ◽

Mei Song ◽

Na Li ◽

Yuan-Yuan Gao ◽

...

Keyword(s):

Risk Factors ◽

Alcohol Use ◽

Alcohol Abuse ◽

Alcohol Dependence ◽

Physical Abuse ◽

Emotional Abuse ◽

Alcohol Use Disorder ◽

Alcohol Use Disorders ◽

Traumatic Experience ◽

Frequent Drinking

Abstract Background We aimed to investigate the effect of early-age (prenatal, infant, and childhood) trauma on adulthood alcohol use disorder. Methods A total number of 1534 subjects who were born and live in the city of Tangshan were selected. The subjects were divided into three age groups. General demographic data, conditions of the mothers during pregnancy, and condition of the babies at birth, were collected. The diagnosis of alcohol use disorder was based on Structured Clinical Interviews for DSM-IV Axis Disorders (patient version) (SCID). The childhood trauma questionnaire short form (CTQ-SF) [1] and the Lifetime of Experience Questionnaire (LTE-Q) [2] were used to evaluate stress in childhood and adulthood, respectively. Results Only male subjects were diagnosed with lifelong alcohol abuse and alcohol dependence. There was no statistically significant difference in the prevalence of lifetime alcohol use disorder (X2 = 4.480, P = 0.345), current alcohol abuse, and current alcohol dependence among the three groups (X2abuse = 2.177, X2depedence = 2.198, P > 0.05). However, higher prevalence of lifetime alcohol use disorders was found in group with higher scores of CTQ (X2 = 9.315, P = 0.009), emotional abuse (X2 = 8.025, P = 0.018), physical abuse (X2 = 20.4080, P < 0.001), but not in the group with higher scores of emotional neglect (X2 = 1.226, P = 0.542), sexual abuse (X2 = 2.779, P = 0.249), physical neglect (X2 = 3.978, P = 0.137), LTE-Q (X2 = 5.415, P = 0.067), and PSQI (X2 = 5.238, P = 0.073). Protective factor for alcohol abuse for men was identified to be heavy drinking (OR = 0.085, 95%CI: 0.011–0.661), and the risk factors for alcohol abuse were identified to be frequent drinking (OR = 2.736, 95%CI: 1.500, 4.988), and consumption of low liquor (OR = 2.563, 95%CI: 1.387, 4.734). Risk factors for alcohol dependence in males were identified to be consumption of low liquor (OR = 5.501, 95%CI: 2.004, 15.103), frequent drinking (OR = 2.680, 95%CI: 1.164, 6.170), and childhood physical abuse (OR = 2.310, 95% CI: 1.026, 5.201). Conclusion Traumatic experience during infant and prenatal periods does not have a strong statistical correlation with alcohol use disorders for male adults. However, subjects with high CTQ scores, experience of emotional abuse and physical abuse show a statistically higher prevalence of lifetime alcohol use disorders. Several risk factors including consumption of low liquor, frequent drinking, and childhood physical abuse contribute to alcohol dependence in male adults.

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Social anxiety disorder and alcohol use disorder co-morbidity in the National Epidemiologic Survey on Alcohol and Related Conditions

Psychological Medicine ◽

10.1017/s0033291709991231 ◽

2009 ◽

Vol 40 (6) ◽

pp. 977-988 ◽

Cited By ~ 116

Author(s):

F. R. Schneier ◽

T. E. Foose ◽

D. S. Hasin ◽

R. G. Heimberg ◽

S.-M. Liu ◽

...

Keyword(s):

Anxiety Disorder ◽

Social Anxiety ◽

Alcohol Use ◽

Alcohol Abuse ◽

Alcohol Dependence ◽

Personality Disorders ◽

Social Anxiety Disorder ◽

Representative Sample ◽

Alcohol Use Disorder ◽

Co Morbidity

BackgroundTo assess the prevalence and clinical impact of co-morbid social anxiety disorder (SAD) and alcohol use disorders (AUD, i.e. alcohol abuse and alcohol dependence) in a nationally representative sample of adults in the United States.MethodData came from a large representative sample of the US population. Face-to-face interviews of 43093 adults residing in households were conducted during 2001–2002. Diagnoses of mood, anxiety, alcohol and drug use disorders and personality disorders were based on the Alcohol Use Disorder and Associated Disabilities Interview Schedule – DSM-IV version.ResultsLifetime prevalence of co-morbid AUD and SAD in the general population was 2.4%. SAD was associated with significantly increased rates of alcohol dependence [odds ratio (OR) 2.8] and alcohol abuse (OR 1.2). Among respondents with alcohol dependence, SAD was associated with significantly more mood, anxiety, psychotic and personality disorders. Among respondents with SAD, alcohol dependence and abuse were most strongly associated with more substance use disorders, pathological gambling and antisocial personality disorders. SAD occurred before alcohol dependence in 79.7% of co-morbid cases, but co-morbidity status did not influence age of onset for either disorder. Co-morbid SAD was associated with increased severity of alcohol dependence and abuse. Respondents with co-morbid SAD and alcohol dependence or abuse reported low rates of treatment-seeking.ConclusionsCo-morbid lifetime AUD and SAD is a prevalent dual diagnosis, associated with substantial rates of additional co-morbidity, but remaining largely untreated. Future research should clarify the etiology of this co-morbid presentation to better identify effective means of intervention.

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Correlates of lifetime alcohol abuse and dependence among older community residents in Brazil

International Psychiatry ◽

10.1192/s1749367600000436 ◽

2009 ◽

Vol 6 (2) ◽

pp. 40-44 ◽

Cited By ~ 1

Author(s):

Gerda G. Fillenbaum ◽

Sergio Luís Blay ◽

Sergio Baxter Andreoli ◽

Fabio Leite Gastal

Keyword(s):

Alcohol Use ◽

Alcohol Abuse ◽

Alcohol Dependence ◽

Alcohol Use Disorder ◽

Social Characteristics ◽

Community Residents ◽

Dsm Iv ◽

Physiological Impact ◽

The Relationship ◽

Alcohol Abuse And Dependence

Misinterpretation in major surveys of alcohol use disorder as described by DSM-IV (Hasin et al, 2007) has raised serious questions regarding the extent of alcohol use disorder, and the relationship between alcohol abuse and alcohol dependence. While the adverse social, physical and mental effects of alcohol misuse are well known (Council on Scientific Affairs, 1996), there is little information on the determinants of alcohol abuse (societal impact) and alcohol dependence (physiological impact). We therefore examined their separate and combined associations with demographic, social and health characteristics in a representative community-resident sample aged 60 years and over. We hypothesised that, while for each of the three groups (those with alcohol abuse, those with alcohol dependence, and those with both) there would be associated demographic characteristics, abuse would be more closely associated with social characteristics, dependence with health characteristics, and the combined presence of abuse and dependence with both social and health characteristics.

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A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder

CNS Spectrums ◽

10.1017/s1092852918001554 ◽

2019 ◽

Vol 24 (6) ◽

pp. 597-604 ◽

Cited By ~ 2

Author(s):

Marcelo Piquet-Pessôa ◽

Samuel R. Chamberlain ◽

Rico S. C. Lee ◽

Gabriela M. Ferreira ◽

Marcelo S. Cruz ◽

...

Keyword(s):

Alcohol Use ◽

Alcohol Abuse ◽

Alcohol Dependence ◽

Clinical Features ◽

Alcohol Use Disorder ◽

Psychiatric Symptoms ◽

Lower Number ◽

Self Report ◽

Addictive Disorders ◽

Behavioral Tendencies

ObjectiveWe assessed self-reported drives for alcohol use and their impact on clinical features of alcohol use disorder (AUD) patients. Our prediction was that, in contrast to “affectively” (reward or fear) driven drinking, “habitual” drinking would be associated with worse clinical features in relation to alcohol use and higher occurrence of associated psychiatric symptoms.MethodsFifty-eight Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) alcohol abuse patients were assessed with a comprehensive battery of reward- and fear-based behavioral tendencies. An 18-item self-report instrument (the Habit, Reward and Fear Scale; HRFS) was employed to quantify affective (fear or reward) and non-affective (habitual) motivations for alcohol use. To characterize clinical and demographic measures associated with habit, reward, and fear, we conducted a partial least squares analysis.ResultsHabitual alcohol use was significantly associated with the severity of alcohol dependence reflected across a range of domains and with lower number of detoxifications across multiple settings. In contrast, reward-driven alcohol use was associated with a single domain of alcohol dependence, reward-related behavioral tendencies, and lower number of detoxifications.ConclusionThese results seem to be consistent with a shift from goal-directed to habit-driven alcohol use with severity and progression of addiction, complementing preclinical work and informing biological models of addiction. Both reward-related and habit-driven alcohol use were associated with lower number of detoxifications, perhaps stemming from more benign course for the reward-related and lack of treatment engagement for the habit-related alcohol abuse group. Future work should further explore the role of habit in this and other addictive disorders, and in obsessive-compulsive related disorders.

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Māori health outcomes in an intensive care unit in Aotearoa New Zealand

Anaesthesia and Intensive Care ◽

10.1177/0310057x21989715 ◽

2021 ◽

pp. 0310057X2198971

Author(s):

M Atif Mohd Slim ◽

Hamish M Lala ◽

Nicholas Barnes ◽

Robert A Martynoga

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

New Zealand ◽

Renal Replacement Therapy ◽

Confidence Interval ◽

Health Outcomes ◽

Odds Ratio ◽

Adjusted Odds Ratio ◽

One Year ◽

Maori Health

Māori are the indigenous people of New Zealand, and suffer disparate health outcomes compared to non-Māori. Waikato District Health Board provides level III intensive care unit services to New Zealand’s Midland region. In 2016, our institution formalised a corporate strategy to eliminate health inequities for Māori. Our study aimed to describe Māori health outcomes in our intensive care unit and identify inequities. We performed a retrospective audit of prospectively entered data in the Australian and New Zealand Intensive Care Society database for all general intensive care unit admissions over 15 years of age to Waikato Hospital from 2014 to 2018 ( n = 3009). Primary outcomes were in–intensive care unit and in-hospital mortality. The secondary outcome was one-year mortality. In our study, Māori were over-represented relative to the general population. Compared to non-Māori, Māori patients were younger (51 versus 61 years, P < 0.001), and were more likely to reside outside of the Waikato region (37.2% versus 28.0%, P < 0.001) and in areas of higher deprivation ( P < 0.001). Māori had higher admission rates for trauma and sepsis ( P < 0.001 overall) and required more renal replacement therapy ( P < 0.001). There was no difference in crude and adjusted mortality in–intensive care unit (16.8% versus 16.5%, P = 0.853; adjusted odds ratio 0.98 (95% confidence interval 0.68 to 1.40)) or in-hospital (23.7% versus 25.7%, P = 0.269; adjusted odds ratio 0.84 (95% confidence interval 0.60 to 1.18)). One-year mortality was similar (26.1% versus 27.1%, P=0.6823). Our study found significant ethnic inequity in the intensive care unit for Māori, who require more renal replacement therapy and are over-represented in admissions, especially for trauma and sepsis. These findings suggest upstream factors increasing Māori risk for critical illness. There was no difference in mortality outcomes.

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The association of gout with an increased risk of hypertension and diabetes mellitus among stroke survivors in New Zealand: A cross-sectional study using routinely collected electronic health data

JRSM Cardiovascular Disease ◽

10.1177/2048004019863239 ◽

2019 ◽

Vol 8 ◽

pp. 204800401986323 ◽

Cited By ~ 2

Author(s):

Dina Eufemia D San Gabriel ◽

Julia Slark

Keyword(s):

Diabetes Mellitus ◽

New Zealand ◽

Confidence Interval ◽

Odds Ratio ◽

Adjusted Odds Ratio ◽

Cross Sectional Study ◽

Stroke Survivors ◽

Sectional Study ◽

Cross Sectional ◽

Increased Risk

Background There is a paucity of data relating to the association of gout with the occurrence of hypertension and diabetes mellitus in patients with stroke. This study aimed to determine the association of gout with the risk of hypertension and diabetes mellitus in a cohort of stroke patients from Auckland, Aotearoa New Zealand. Methods A cross-sectional study was conducted among stroke survivors in South and East Auckland, New Zealand from the years 2010 to 2014. Electronic health record data were collected and analysed using Statistical Package for Social Science version 23. Multivariate logistic regression modelling adjusted for age, gender, and ethnicity was conducted to determine the association of gout with the risk of hypertension and diabetes mellitus in patients discharged with a diagnosis of stroke. Results The age-, gender-, and ethnicity-adjusted odds ratio for having hypertension and diabetes mellitus among stroke survivors with gout history were 3.25 (95% confidence interval 1.32–8.03) and 1.94 (95% confidence interval 1.12–3.36), respectively. Māori stroke survivors with gout history had the highest risk of having diabetes mellitus with age- and gender-adjusted odds ratio of 5.10 (95% confidence interval 1.90–18.93). Conclusion The findings from this study suggest gout may be independently associated with an increased risk of hypertension and diabetes mellitus in patients with stroke. Māori who are the indigenous population of New Zealand show a greater risk of diabetes mellitus associated with a gout diagnosis compared to other populations. This finding highlights the importance of the need for further research with Māori stroke survivors and other indigenous populations.

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Alcohol, Marijuana, and Dating Abuse Perpetration by Young Adults: Results of a Daily Call Study

Violence Against Women ◽

10.1177/1077801218781959 ◽

2018 ◽

Vol 24 (10) ◽

pp. 1187-1206 ◽

Cited By ~ 3

Author(s):

Emily F. Rothman ◽

Gregory L. Stuart ◽

Jeff R. Temple ◽

Timothy Heeren

Keyword(s):

Young Adults ◽

Alcohol Use ◽

Confidence Interval ◽

Odds Ratio ◽

Temporal Order ◽

Marijuana Use ◽

Elevated Risk ◽

Dating Abuse ◽

Daily Data

The purpose of this study was to investigate same-day alcohol or marijuana use and dating abuse (DA) perpetration in a sample of 60 noncollege-attending young adults. Participants reported daily data for 3 months. DA perpetration was more likely on days when participants also reported alcohol use (odds ratio [OR] = 2.17, 95% confidence interval [CI] = [1.38, 3.42]), but analyses of the temporal order indicated that alcohol use was not a proximal predictor of DA. Same day marijuana use was not associated with elevated risk of DA perpetration (OR = 1.40, 95% CI = [0.89, 2.21]). Results suggest the alcohol–DA relationship may vary by sample and context.

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Association of Picornavirus Infections With Acute Otitis Media in a Prospective Birth Cohort Study

The Journal of Infectious Diseases ◽

10.1093/infdis/jiaa087 ◽

2020 ◽

Vol 222 (2) ◽

pp. 324-332

Author(s):

Elina M Seppälä ◽

Sami Oikarinen ◽

Jussi P Lehtonen ◽

Subas Neupane ◽

Hanna Honkanen ◽

...

Keyword(s):

Confidence Interval ◽

Birth Cohort ◽

Otitis Media ◽

Odds Ratio ◽

Adjusted Odds Ratio ◽

Quantitative Polymerase Chain Reaction ◽

Population Attributable Risk ◽

Acute Otitis Media ◽

Attributable Risk ◽

Prospective Birth Cohort

Abstract Background Human rhinoviruses (HRVs), human enteroviruses (HEVs) and human parechoviruses (HPeVs) have been linked to acute otitis media (AOM). We evaluated this association in a prospective birth cohort setting. Methods A total of 324 healthy infants were followed up from birth to age 3 years. Nasal swab samples were collected at age 3, 6, 12, 18, 24, and 36 months and screened for HRV and HEV using real-time reverse-transcription quantitative polymerase chain reaction. Stool samples were collected monthly and analyzed for HRV, HEV, and HPeV. AOM episodes diagnosed by physicians were reported by parents in a diary. The association of viruses with AOM was analyzed using generalized estimation equations, and their relative contributions using population-attributable risk percentages. Results A clear association was found between AOM episodes and simultaneous detection of HEV (adjusted odds ratio for the detection of virus in stools, 2.04; 95% confidence interval, 1.06–3.91) and HRV (1.54; 1.04–2.30). HPeV showed a similar, yet nonsignificant trend (adjusted odds ratio, 1.44; 95% confidence interval, .81–2.56). HRV and HEV showed higher population-attributable risk percentages (25% and 20%) than HPeV (11%). Conclusions HEVs and HRVs may contribute to the development of AOM in a relatively large proportion of cases.

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Alcohol craving and the dimensionality of alcohol disorders

Psychological Medicine ◽

10.1017/s003329171000053x ◽

2010 ◽

Vol 41 (3) ◽

pp. 629-640 ◽

Cited By ~ 61

Author(s):

K. M. Keyes ◽

R. F. Krueger ◽

B. F. Grant ◽

D. S. Hasin

Keyword(s):

Alcohol Use ◽

Alcohol Dependence ◽

Latent Variable ◽

Alcohol Use Disorder ◽

Alcohol Problems ◽

Continuous Measure ◽

Alcohol Disorders ◽

Alcohol Craving ◽

Epidemiologic Survey ◽

Dsm Iv

BackgroundICD-10 includes a craving criterion for alcohol dependence while DSM-IV does not. Little is known about whether craving fits with or improves the DSM-IV criteria set for alcohol-use disorders.MethodData were derived from current drinkers (n=18 352) in the 1991–1992 National Longitudinal Alcohol Epidemiologic Survey (NLAES), a nationally representative survey of US adults >17 years of age. The Alcohol Use Disorder and Associated Disabilities Interview Schedule was used to assess the eleven DSM-IV dependence and abuse criteria, and alcohol craving. Exploratory factor, item response theory, and regression analyses were used to evaluate the psychometric properties and concurrent validity of DSM-based alcohol disorder criteria with the addition of alcohol craving.ResultsThe past 12-month prevalence of craving was 1.3%. Craving formed part of a unidimensional latent variable that included existing DSM-IV criteria. Craving demonstrated high severity on the alcohol-use disorder continuum, resulting in an improved dimensional model with greater discriminatory ability compared with current DSM-IV criteria. Correlates of the diagnosis did not change with the addition of craving, and past 12-month craving was associated with prior alcohol dependence, depression, and earlier age of alcohol disorder onset among those with current DSM-IV alcohol dependence.ConclusionsThe addition of craving to the existing DSM-IV criteria yields a continuous measure that better differentiates individuals with and without alcohol problems along the alcohol-use disorder continuum. Few individuals are newly diagnosed with alcohol dependence given the addition of craving, indicating construct validity but redundancy with existing criteria.

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Connections between personality and the symptomatology of alcohol use disorder

European Psychiatry ◽

10.1016/s0924-9338(11)71782-5 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 71-71

Author(s):

E. Kurgyis ◽

B. Andó ◽

S. Rózsa ◽

A. Szkaliczki ◽

I. Demeter ◽

...

Keyword(s):

Alcohol Use ◽

Alcohol Dependence ◽

Symptom Severity ◽

Impulse Control ◽

Alcohol Use Disorder ◽

Specific Impulse ◽

Personality Factors ◽

Clinical Aspects ◽

Novelty Seeking ◽

Dsm Iv

IntroductionTemperament and character factors and specific impulse control-related personality traits are connected to the developmental and clinical aspects of alcohol use disorder (AUD).Objectives/aimsTo reveal the underlying personality structure of individual differences in the symptom severity of AUD. Therefore temperament and character, impulsivity and aggression were assessed in relation to alcohol addiction severity.MethodsSixty-three patients with AUD were involved. Temperament and Character Inventory-Revised was used to quantify temperament and character dimensions. Impulsivity was assessed by the Barratt Impulsivity Scale-11 (BIS) and aggression by the Buss-Perry Aggression Questionnaire (BPAQ). To determine symptom severity of AUD the Severity of Alcohol Dependence Questionnaire (SADQ), the Alcohol Use Disorders Identification Test (AUDIT), the MacAndrew Alcoholism Scale-Revised (MAC-R) and the number of DSM-IV alcohol dependence symptoms were registered. To analyze the connections between symptom severity indicators and personality factors Pearson and Spearman correlation analysis were applied, p < 0.05 were considered significant.ResultsSADQ (r = 0.290), AUDIT (r = 0.345), MAC-R (r = 0.504) and the DSM-IV alcohol dependence symptoms (Spearman rho = 0.271) correlated positively with novelty-seeking temperament factor. SADQ (r = 0.262) and AUDIT (r = 0.293) scores correlated positively with BIS. Furthermore SADQ (r = 0.382), AUDIT (r = 0.318), MAC-R (r = 0.416) correlated positively with BPAQ.ConclusionsNovelty-seeking, impulsivity and aggression as indicators of impulse control have different theoretical backgrounds but a common root. This study has revealed that the adverse consequences of lower impulse control can lead to more severe symptoms of AUD. These connections between impulse control and the symptomatology could contribute to a better understanding of the clinical complexity of AUD.

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