scholarly journals Different chest CT scoring systems in patients with COVID-19: could baseline CT be a helpful tool in predicting survival in patients with matched ages and co-morbid conditions?

2021 ◽  
pp. 028418512110063
Author(s):  
Okan Dilek ◽  
Emin Demirel ◽  
Hüseyin Akkaya ◽  
Mehmet Cenk Belibagli ◽  
Gokhan Soker ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Severity Score ◽  
Area Under The Curve ◽  
Scoring Systems ◽  
Survival Prediction ◽  
Success Rates ◽  
Survival Times ◽  
The Mean ◽  
Early Decision ◽  
Age Range

Background Computed tomography (CT) gives an idea about the prognosis in patients with COVID-19 lung infiltration. Purpose To evaluate the success rates of various scoring methods utilized in order to predict survival periods, on the basis of the imaging findings of COVID-19. Another purpose, on the other hand, was to evaluate the agreements among the evaluating radiologists. Material and Methods A total of 100 cases of known COVID-19 pneumonia, of which 50 were deceased and 50 were living, were included in the study. Pre-existing scoring systems, which were the Total Severity Score (TSS), Chest Computed Tomography Severity Score (CT-SS), and Total CT Score, were utilized, together with the Early Decision Severity Score (ED-SS), which was developed by our team, to evaluate the initial lung CT scans of the patients obtained at their initial admission to the hospital. The scans were evaluated retrospectively by two radiologists. Area under the curve (AUC) values were acquired for each scoring system, according to their performances in predicting survival times. Results The mean age of the patients was 61 ± 14.85 years (age range = 18–87 years). There was no difference in co-morbidities between the living and deceased patients. The survival predicted AUC values of ED-SS, CT-SS, TSS, and Total CT Score systems were 0.876, 0.823, 0.753, and 0.744, respectively. Conclusion Algorithms based on lung infiltration patterns of COVID-19 may be utilized for both survival prediction and therapy planning.

scholarly journals Evaluation of prediction score of contrast-induced nephropathy in inpatients undergone to digital or CT angiography

2020 ◽  
Vol 10 (3) ◽  
pp. 78-84
Author(s):  
Seleno Glauber de Jesus-Silva ◽  
Ana Elisa Chaves ◽  
Caio Augusto Alves Maciel ◽  
Edson Eziel Ferreira Scotini ◽  
Pablo Girardelli Mendonça Mesquita ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Roc Curve ◽  
Computed Tomography Angiography ◽  
Score Test ◽  
Area Under The Curve ◽  
Roc Curve Analysis ◽  
Contrast Induced Nephropathy ◽  
Mean Values ◽  
Iodinated Contrast ◽  
The Mean

Objectives: To assess the incidence of contrast-induced nephropathy (CIN) and determine the Mehran Score's (MS) ability to predict CIN in patients undergoing digital angiography or computed tomography angiography. Methods: 252 medical records of inpatients who underwent DA or CTA over 28 months in a quaternary hospital were reviewed. CIN was defined as serum creatinine> 0.5 mg / dL or > 25% increase in baseline creatinine, 48 h after administration of iodinated contrast. The ROC curve and the area under the curve (AUC) were used as a score test. Results: The majority (159; 63.1%) were male, and the average age was 60.4 years. Anemia, diabetes mellitus, and age > 75 years were the most prevalent factors. The incidence of CIN was 17.8% (n = 45). There was a decrease in the mean values ​​of creatinine pre and post among patients who did not suffer CIN (1.38 ± 1.22 vs 1.19 ± 0.89; t = 3.433; p = 0.0007), while among patients who suffering CIN, the mean increase was 1.03 mg / dL (1.43 ± 1.48 vs 2.46 ± 2.35 mg / dL; t = 5.44; p = 0.117). The ROC curve analysis identified a low correlation between MS and the occurrence of CIN (AUC = 0.506). Conclusion: The incidence of CIN in hospitalized patients undergoing angiography or computed tomography angiography was high. The EM did not allow the prediction of NIC.

scholarly journals The comparison of two risk prediction models specific for COVID-19: The Brescia-COVID Respiratory Severity Scale versus the Quick COVID-19 Severity Index

2021 ◽  
pp. 1-17
Author(s):  
Rohat AK ◽  
Erdem KURT ◽  
Suphi BAHADIRLI
Keyword(s):  
Hospital Mortality ◽  
Prediction Models ◽  
Area Under The Curve ◽  
Prediction Rule ◽  
Scoring Systems ◽  
Severity Index ◽  
Severity Scale ◽  
Risk Prediction Models ◽  
Icu Admission ◽  
The Mean

Abstract Objective: This study compared the prognostic performances of the Brescia-COVID Respiratory Severity Scale (BCRSS) and the Quick COVID-19 Severity Index (qCSI) scores in hospitalized patients diagnosed with COVID-19. Methods: The data of all adult patients (over 18 years of age) who were admitted into a state hospital with confirmed COVID-19 between May 1, 2020 and October 31, 2020 were retrospectively examined. The area under the receiver operating characteristic (ROC) curve, known as the area under the curve (AUC), was used to assess the BCRSS prediction rule and the qCSI score to assess the discriminatory power in predicting in-hospital mortality and intensive care unit (ICU) admission. Results: There were 341 patients included in this study. The mean age of the patients was 58.2 ± 17.2, of which 165 were men and 176 were women, and 61.3% of patients had at least one comorbidity. The most common comorbidity was hypertension. The predictive power scores of BCRSS and qCSI were found as very good in terms of in-hospital mortality (AUC 0.804 and 0.847, respectively) and likewise in terms of ICU admission (AUC 0.842 and 0.851, respectively). Conclusion: Both BCRSS and qCSI scoring systems were found to be successful in predicting in-hospital mortality and ICU admission in our patient population.

scholarly journals Clinical use of the poisoning severity score in acute pediatric poisoning

2021 ◽  
Vol 38 (4) ◽  
pp. 565-570
Author(s):  
Fatih ÇALIŞKAN ◽  
Gülfer AKÇA ◽  
Burcu ÇALIŞKAN ◽  
Ünal AKÇA
Keyword(s):  
Severity Score ◽  
Emergency Service ◽  
Pediatric Emergency ◽  
Accurate Diagnosis ◽  
Pediatric Emergency Department ◽  
Research And Practice ◽  
The Mean ◽  
Physiological Values ◽  
Poisoning Severity Score ◽  
Age Range

To make an accurate diagnosis of poisoning and determine the severity of poisoning quickly without losing time are critical for managing the patient's medical treatment and predicting the prognosis. This study aimed to investigate PSS and Glasgow Coma Scale Score (GCS) effectiveness in predicting outcomes in acute pediatric poisoning. We retrospectively reviewed the data of intoxicated patients aged under 18 years who were admitted to the pediatric emergency service of Ondokuz Mayıs University Faculty of Medicine Clinical Research and Practice Hospital between January 1, 2018, and December 31, 2018. Two hundred twenty-two patients were admitted to our pediatric emergency department (ED) after drug ingestions. Of the patients enrolled in the study, 148 (66.7 %) were female, and 74 (33.3%) were male. The mean age was 105.8±75.3 months, and the median age was 65 (12-213) months. 96 (43.3%) poisoning cases were in the age range of 12-18 years. According to Poisoning Severity Score, it was found that 84 cases (37.4%) were asymptomatic (PSS score=0), 86 cases (38.7%) were minor (PSS score=1), 48 cases (21.6%) were moderate (score=2) and four cases (1.8%) were severe (PSS score=3). Combined using the Poisoning Severity Score with the patient's biochemical and physiological values may help improve an accurate diagnosis of poisoning and determine the severity of poisoning more accurately.

scholarly journals The mean severity score and its correlation with common computed tomography chest manifestations in Egyptian patients with COVID-2019 pneumonia

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Mona A. F. Hafez
Keyword(s):  
Computed Tomography ◽  
Disease Severity ◽  
Severity Score ◽  
Descriptive Analysis ◽  
Multislice Ct ◽  
Mediastinal Lymphadenopathy ◽  
Diagnostic Tools ◽  
Ct Findings ◽  
Egyptian Patients ◽  
The Mean

Abstract Background Computed tomography (CT) is one of the main diagnostic tools for early detection and management of coronavirus disease 2019 (COVID-19) pneumonia. This study aims to highlight the commonly encountered CT findings in patients with COVID-19 pneumonia in Egypt and the mean severity score and its correlation with the imaging findings. This study involved 200 patients with pathologically confirmed COVID-19 infection; non-contrast CT chest was performed for all cases; in addition, CT findings and severity score (CT-SS) were then assessed using descriptive analysis, and the correlation between the CT findings and disease severity was assessed. Results The ground-glass densities and peripheral adhesions were the most typical CT findings. Prominent interlobular septations; bronchial thickening/dilatation; CT signs of crazy-paving, halo, and reversed halo; and reactive mediastinal lymphadenopathy were significantly correlated with disease severity. The mean CT-SS of Egyptian patients with COVID-19 pneumonia was 11.2 (mild to moderate severity). Conclusion Multislice CT played a vital role in the early identification of Egyptian patients with COVID-19 pneumonia. The assessment of the CT severity score of COVID-19 is essential for the extent of pneumonia involvement to help clinicians achieve the purpose of early diagnosis and accurate treatment.

scholarly journals Correlation between D-dimer and computed tomography severity score in middle aged young adults with COVID-19 pneumonia: a retrospective study

2021 ◽  
Author(s):  
Deepak Kumar A. ◽  
Sachin N. Solanke
Keyword(s):  
Computed Tomography ◽  
Retrospective Study ◽  
Severity Score ◽  
Rt Pcr ◽  
Wuhan City ◽  
Medical College ◽  
Coagulation Tests ◽  
The Mean ◽  
D Dimer ◽  
Time Point

Background: An unknown pneumonia broke out in Wuhan City in December 2019 and it was confirmed as an acute respiratory infectious disease caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2, formerly known as 2019-nCoV). Consumption coagulopathy, which should be obviated in order to decrease mortality, arises in disseminated intravascular coagulation with a decrease in fibrinogen and an increase in D-dimer levels. However, studies on the predictive and prognostic values of coagulation parameters in the setting of patients with COVID-19 are still limited. The objective of this retrospective study was to investigate the correlation of D-dimer and computed tomography severity score in patients with COVID-19 pneumonia.Methods: The present retrospective study was conducted among 108 subjects reported COVID RT-PCR positive admitted during the study period i.e.; January-August 2021 in the department of medicine of Rural Medical College, Loni. Pneumonia was confirmed by Computed tomography (CT) examination and coagulation test completed within 12 hr after admission were enrolled. Coagulation tests, which Fibrinogen (Fib) and D-dimer were performed. CT score was categorized into mild (0-7), moderate (8-16) and advanced grade (17-25 points).Results: The mean age of male and female was 38.52±5.34 and 35.67±3.22 years respectively, with an overall age of 37.79±4.58 years. Mean D-dimer level was 0.54±0.09, 0.91±0.22 and 1.96±0.47 mcg/ml among subjects having mild, moderate and severe CT score respectively. According to multivariate analysis, higher D-dimer (OR:3.61, p<0.01) was significantly associated with CT severity score.Conclusions: Study concluded that the D-dimer level's time point was matched to the time of CT scan, we have reasons to correlate that the D-dimer level may predict the severity of inflammation prior to coagulopathy/thrombosis.

scholarly journals Computed tomography severity scoring of COVID 19 infected young patients: Is the second wave affecting the young lungs more than the first wave in India?

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Omair Shah ◽  
Shadab Maqsood ◽  
Tahleel Shera ◽  
Mudasir Bhat ◽  
Naseer Choh ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Severity Score ◽  
Young Patients ◽  
Severity Scoring ◽  
Number Of Patients ◽  
Severity Scores ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Second Wave

We evaluated the High Resolution Computed Tomography (HRCT) findings in young patients (< 40 years) infected with the COVID 19 virus and tried to find out any difference in the severity of lung involvement between the first and second wave of the pandemic and whether the notion of young population being more severely affected by the second wave holds true.Two-hundred (200) young patients (<40 years) with RT PCR documented COVID infections undergoing HRCT chest at our institute were included. Group A included young patients infected in the first wave (up to 28 February 2021) while Group B included patients beyond this date. Demographic and clinical data was obtained from the medical records department. HRCT scans were retrieved from the archive and were assessed by two radiologists or CT severity scoring. The mean severity scores were calculated and any statistical difference between Group A and B was sought. CT scans of four fully vaccinated patients were also evaluated.The age and gender distribution among the two groups was comparable. A greater number of patients in group B required hospital admission compared to group A (74% VS 53%). In group A, the mean severity score was 10.1±2.1 with 34 patients (34%) in mild category, 46 patients (46%) in moderate group and 20 patients (20%) in the severe group. In group B, the mean CT severity score was 12.6±2.3 with 20 patients (20%) in mild category, 42 patients (42%) in moderate group and 38 patients (38%) in the severe group.Lung involvement in young patients in the second wave is more severe requiring more hospital admissions. Vaccinated population may well have a milder form of the disease.

scholarly journals Efficacy and comparison of appendicitis inflammatory response score with Alvarado score in predicting the diagnosis of acute appendicitis

2019 ◽  
Vol 6 (8) ◽  
pp. 2843
Author(s):  
Abhishek Kumar ◽  
K. G. Byakodi ◽  
Prathamesh P. Chandrapattan ◽  
Vasant Teggimani
Keyword(s):  
Acute Appendicitis ◽  
Area Under The Curve ◽  
Scoring Systems ◽  
Alvarado Score ◽  
Discriminating Power ◽  
Study Population ◽  
Male Patients ◽  
The Mean ◽  
Response Score ◽  
Better Than

Background: Aute appendicitis being the most common surgical emergency poses a significant diagnosing dilemma. Early diagnosis has very favourable outcomes and if diagnosis is delayed leads to significant morbidity and mortality. USG has some limitations and best investigation computed tomography (CT) is being overused which leads to unnecessary exposure to radiation especially in children and young adult. Scoring systems are a valuable aid when it comes to diagnosing appendicitis.Methods: Study done in department of surgery in KIMS, Hubli. The study period was December 2015– September 2016, and 107 patients with right lower abdomen pain were studied. History, clinical examination, biochemical, haematological, radiological investigations were done. Alvarado and AIR scores were calculated. Considering HPR report as gold standard the scores were compared.Results: There were 70 male patients (66%) and 37 female patients (34%). The mean age in our study population was 28.1 years ±13.57 years. The overall area under the receiver operating characteristic (ROC) curve of the AIR score was 0.967 and significantly better than the area under the curve of 0.825 of the Alvarado score (p=0.05).Conclusions: This study externally validates the AIR score for patients with acute appendicitis. The scoring system has a high discriminating power compared to Alvarado score especially in cases in which appendicitis is difficult to diagnose such as females, children, elderly, in advanced cases and very effective supplement to available radiological investigations.

Computed Tomography-Based Patient-Specific Instrumentation Loses Accuracy with Significant Varus Preoperative Misalignment

2020 ◽  
Author(s):  
Vicente Jesús León-Muñoz ◽  
Mirian López-López ◽  
Alonso José Lisón-Almagro ◽  
Francisco Martínez-Martínez ◽  
Fernando Santonja-Medina
Keyword(s):  
Computed Tomography ◽  
Deformity Correction ◽  
Patient Specific ◽  
Control Group ◽  
X Rays ◽  
Varus Alignment ◽  
Patient Specific Instrumentation ◽  
Conventional Instrumentation ◽  
The Mean ◽  
Valgus Alignment

AbstractPatient-specific instrumentation (PSI) has been introduced to simplify and make total knee arthroplasty (TKA) surgery more precise, effective, and efficient. We performed this study to determine whether the postoperative coronal alignment is related to preoperative deformity when computed tomography (CT)-based PSI is used for TKA surgery, and how the PSI approach compares with deformity correction obtained with conventional instrumentation. We analyzed pre-and post-operative full length standing hip-knee-ankle (HKA) X-rays of the lower limb in both groups using a convention > 180 degrees for valgus alignment and < 180 degrees for varus alignment. For the PSI group, the mean (± SD) pre-operative HKA angle was 172.09 degrees varus (± 6.69 degrees) with a maximum varus alignment of 21.5 degrees (HKA 158.5) and a maximum valgus alignment of 14.0 degrees. The mean post-operative HKA was 179.43 degrees varus (± 2.32 degrees) with a maximum varus alignment of seven degrees and a maximum valgus alignment of six degrees. There has been a weak correlation among the values of the pre- and postoperative HKA angle. The adjusted odds ratio (aOR) of postoperative alignment outside the range of 180 ± 3 degrees was significantly higher with a preoperative varus misalignment of 15 degrees or more (aOR: 4.18; 95% confidence interval: 1.35–12.96; p = 0.013). In the control group (conventional instrumentation), this loss of accuracy occurs with preoperative misalignment of 10 degrees. Preoperative misalignment below 15 degrees appears to present minimal influence on postoperative alignment when a CT-based PSI system is used. The CT-based PSI tends to lose accuracy with preoperative varus misalignment over 15 degrees.

scholarly journals Correlation between serum carbohydrate antigen 19-9 levels and computed tomography severity score in patients with nontuberculous mycobacterial pulmonary disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kangjoon Kim ◽  
Seung Hyun Yong ◽  
Su Hwan Lee ◽  
Sang Hoon Lee ◽  
Ah Young Leem ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Disease Activity ◽  
Pulmonary Disease ◽  
Severity Score ◽  
Partial Correlation ◽  
Elevated Serum ◽  
Carbohydrate Antigen ◽  
Chest Ct ◽  
Clinical Biomarker ◽  
Serum Carbohydrate Antigen

AbstractThere is no validated clinical biomarker for disease severity or treatment response for nontuberculous mycobacterial pulmonary disease (NTM-PD). We investigated the correlation between elevated serum carbohydrate antigen (CA) 19-9 levels and NTM-PD disease activity, defined using an imaging severity score based on chest computed tomography (CT). We retrospectively examined 79 patients with NTM-PD who underwent serum CA19-9 level assessments and chest CT less than 1 month apart. NTM-PD severity was rated using a CT-based scoring system. The correlation between the CT score and serum CA19-9 levels was evaluated. Chest CT revealed nodular bronchiectasis without cavitation in most patients (78.5%). Serum CA19-9 levels were elevated in 19 (24%) patients. Serum CA19-9 levels were positively correlated with the total CT score and bronchiectasis, bronchiolitis, cavity, and consolidation subscores. Partial correlation analysis revealed a significant positive correlation between serum CA19-9 levels and CT scores for total score and bronchiectasis, bronchiolitis, cavitation, and consolidation subscores after controlling for age, sex, and BMI. Serum CA19-9 levels were positively correlated with the CT severity score for NTM-PD. Serum CA19-9 may be useful in evaluating disease activity or therapeutic response in patients with NTM-PD.

scholarly journals Metacarpal Bony Dimensions Related to Headless Compression Screw Sizes

2019 ◽  
Vol 12 (S 01) ◽  
pp. S39-S44
Author(s):  
Michael Okoli ◽  
Kevin Lutsky ◽  
Michael Rivlin ◽  
Brian Katt ◽  
Pedro Beredjiklian
Keyword(s):  
Computed Tomography ◽  
Fracture Fixation ◽  
Ct Scans ◽  
Compression Screw ◽  
Metacarpal Head ◽  
Headless Compression Screw ◽  
Metacarpal Bones ◽  
Headless Compression Screws ◽  
The Mean ◽  
Distal Aspect

Abstract Introduction The purpose of this study is to determine the radiographic dimensions of the finger metacarpals and to compare these measurements with headless compression screws commonly used for fracture fixation. Materials and Methods We analyzed computed tomography (CT) scans of the index, long, ring, and small metacarpal bones and measured the metacarpal length, distance from the isthmus to the metacarpal head, and intramedullary diameter of the isthmus. Metacarpals with previous fractures or hardware were excluded. We compared these dimensions with the size of several commercially available headless screws used for intramedullary fixation. Results A total of 223 metacarpals from 57 patients were analyzed. The index metacarpal was the longest, averaging 67.6 mm in length. The mean distance from the most distal aspect of the metacarpal head to the isthmus was 40.3, 39.5, 34.4, and 31 mm for the index, long, ring, and small metacarpals, respectively. The narrowest diameter of the isthmus was a mean of 2.6, 2.7, 2.3, and 3 mm for the index, long, ring, and small metacarpals, respectively. Of 33 commercially available screws, only 27% percent reached the isthmus of the index metacarpal followed by 42, 48, and 58% in the long, ring, and small metacarpals, respectively. Conclusion The index and long metacarpals are at a particular risk of screw mismatch given their relatively long lengths and narrow isthmus diameters.

Sign in / Sign up

Export Citation Format

Share Document