scholarly journals Severity and frequency of restless legs syndrome in patients with familial Mediterranean fever

2017 ◽  
Vol 45 (4) ◽  
pp. 1340-1346
Author(s):  
Samet Yılmaz ◽  
Burhanettin Çiğdem ◽  
Şeyda Figül Gökçe ◽  
Sevil Ceyhan-Doğan ◽  
Hatice Balaban
Keyword(s):  
Familial Mediterranean Fever ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Inflammatory Diseases ◽  
Normal Population ◽  
Motor Disorder ◽  
Restless Legs ◽  
Mediterranean Fever ◽  
The Mean

Objective: Restless legs syndrome (RLS) is a common sensory motor disorder. RLS an urge to move the extremities that may be accompanied by dysesthesias, and significantly affects quality of life of affected patients. The frequency of RLS is higher in different systemic inflammatory diseases. Familial Mediterranean fever (FMF) is an inherited inflammatory disease characterized by attacks of polyserositis, arthritis, and fever. The prevalence of RLS in patients with FMF is unknown. This study aimed to evaluate the prevalence rate of RLS in a sample of patients with FMF and compare this prevalence with that of a matched normal population. Method: A total of 60 patients with FMF and 60 healthy controls were studied. All participants underwent a neurological examination. Diagnostic criteria as proposed by the International Restless Legs Syndrome Study Group (IRLSSG) were used to define RLS. The IRLSSG rating scale for the severity of RLS was applied to determine the severity of symptoms. Results: The prevalence of RLS was not significantly different between patients and controls. Although the mean International Restless Legs Syndrome Rating Scale (IRLSRS) scores tended to be higher in patients compared with controls, this difference was not significant. When each item of the severity scale was compared between the two groups, significantly higher scores were found in some items of the IRLSRS in patients with FMF compared with controls. Conclusion: According to this result, RLS symptoms in patients with FMF were more frequent and lasted longer than those in controls.

scholarly journals Restless legs syndrome and quality of life in pregnant women

2019 ◽  
Vol 65 (5) ◽  
pp. 618-624
Author(s):  
Pınar Akbaş ◽  
Şengül Yaman Sözbir
Keyword(s):  
Quality Of Life ◽  
Pregnant Women ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Short Form ◽  
Restless Legs ◽  
Sf 36 ◽  
Study Results ◽  
The Mean

SUMMARY OBJECTIVE: In this study, we aimed to determine the extent of restless legs syndrome (RLS) in pregnant women and evaluate the relationship between the syndrome and quality of life. METHODS: This is a cross-sectional descriptive study. A questionnaire developed by the researcher, the Short Form 36 (SF-36) Questionnaire to measure the quality of life, the International Restless Legs Syndrome Study Group (IRLSSG) Diagnostic Criteria for RLS and the Restless Legs Syndrome Rating Scale were applied to the women to collect the data. A total of 250 pregnant women were included in the study. RESULTS: The mean age of the women was 28.11 ± 5.59 years and the mean gestational time was 26.26 ± 10.72 weeks. Symptoms of RLS were seen in 46.4 % of the women. The mean for the RLS Violence Rating Score was 20.82 ± 6.61 for the women with RLS. RLS was found to be mild in 5.2 % of the women, moderate in 45.7 %, severe in 40.5 % and very severe in 8.6 %. A statistically significant effect of RLS survival on quality of life was observed. CONCLUSION: These results indicate that almost half of the pregnant women in this study experienced RLS, and about half of those with RLS experienced severe or very severe RLS. There is a significant relationship between RLS and six domains of SF-36 (physical, role limitations, pain, general health perception, energy/vitality, and mental health).

The Relationship between Restless Legs Syndrome and Quality of Life in Patients with Myasthenia Gravis

2019 ◽  
Vol 81 (3-4) ◽  
pp. 205-208
Author(s):  
Monica F. Ataide ◽  
Carolina da Cunha-Correia ◽  
Katia C.L. Petribú
Keyword(s):  
Quality Of Life ◽  
Myasthenia Gravis ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Study Population ◽  
Clinical Conditions

Background: Restless legs syndrome (RLS) is characterized for an uncomfortable sensation in legs and an irresistible desire to move them. This disorder has been more recently recognized in patients with myasthenia gravis (MG) and can interfere with the quality of life (QOL). Objectives: The aims of this study are to describe the prevalence of RLS and its severity and influence on the QOL in patients with MG. Method: This was a cross-sectional study conducted from May to June 2016 in Recife, Brazil. A sample of 42 patients was interviewed using a sociodemographic questionnaire, MG QOL questionnaire-15 and The RLS Rating Scale. Results: RLS was present in 47.6% of patients and of these 40.5% met moderate to severe RLS criteria. Patients were 45 years on average (SD ± 14.4) and women represented 57.1% of the study population. Among patients with RSL, the quality-of-life scores were worse (p = 0.010) on average. There was no association of RLS with the duration of MG, use of immunosuppressant or clinical conditions that could mimic the occurrence of RLS. Conclusion: RLS is a prevalent condition in patients with MG, and may be severe enough to negatively impact QOL.

scholarly journals Relationship between Demographic Characteristics, Depression and Insomnia with Restless Legs Syndrome: a Study of Adults Aged 17-70 Years in Yazd 2019

2020 ◽  
Author(s):  
Mohammad Hossein Sorbi ◽  
Ali Issazadegan ◽  
Esmaiel Soleimani ◽  
Hamid Mirhosseini
Keyword(s):  
Standard Deviation ◽  
Linear Regression ◽  
Restless Legs Syndrome ◽  
Pearson Correlation ◽  
Demographic Characteristics ◽  
T Test ◽  
Cluster Sampling ◽  
Motor Disorder ◽  
Restless Legs ◽  
The Mean

Introduction: Restless legs syndrome (RLS) is a neurological-motor disorder in which most patients tend to shake their legs during sleep and describe it as an unpleasant feeling. The aims of this study were to determine the prevalence of RLS, its relationship with demographic characteristics, depression, and insomnia and comparison of the mentioned variables in the group with and without RLS.  Methods: This was a case-control analytic study. The sample consisted of 429 adults aged 17-70 years who had referred all the psychiatric and neurological clinics of Yazd (center of Iran) in 2019. Participants were selected by cluster sampling method. Research tools included a demographic questionnaire, the Beck Depression Inventory (BDI-II), Insomnia Severity Index (ISI), and an International Restless Legs Syndrome Questionnaire (IRLSQ). The data were analyzed by SPSS-21, chi-square, Pearson correlation coefficient, independent t-test, and linear regression. Significant level was considered 0.05. Results: The mean and standard deviation of the age of participants was 34.43± 10.82. Furthermore, the mean and standard deviation of the age group with RLS was 36.07± 10.95 while in group without RLS was 33.92± 10.75. Prevalence of RLS in adults was 23.5% (n= 101), in women was 32% (n= 66) and in men was 28.7% (n= 35). The t-test showed patients with RLS had a higher degree of depression and insomnia than those without RLS (p<0.05). Multiple linear regression also showed that insomnia (β= 0.36), age (β= 0.13), and depression (β= 0.15) had a significant effect on RLS score.  Conclusion: The prevalence of RLS among adults in Yazd is high. Severe insomnia, depressed mood, and aging are considered as important factors in predicting this disease. According to what was mentioned early detection, prevention, and treatment of this disorder in adults is necessary.

Efficacy of neuromuscular electric stimulation versus aerobic exercise on uraemic restless legs syndrome

2019 ◽  
Vol 26 (10) ◽  
pp. 1-12
Author(s):  
Manal K Youssef
Keyword(s):  
Aerobic Exercise ◽  
Physical Performance ◽  
Restless Legs Syndrome ◽  
Electric Stimulation ◽  
Rating Scale ◽  
Neuromuscular Electrical Stimulation ◽  
Motor Disorder ◽  
Stand Test ◽  
Restless Legs ◽  
Sit To Stand

Background The prevalence of restless legs syndrome in haemodialysis patients is approximately ~30%, and it is significantly higher than in the general population. Restless legs syndrome is a sensory-motor disorder with negative effects on sleep and daytime activities that affect personal, family and occupational life. The overall impact of restless legs syndrome on quality of life is comparable to that of chronic and frustrating conditions such as depression and diabetes. The present study was conducted to compare the effect of neuromuscular electric stimulation with aerobic exercise on cases of uraemic restless legs syndrome. Methods A total of 60 chronic renal failure patients with uraemic restless legs syndrome aged 20 to 65 years participated in this study. Participants were allocated to receive neuromuscular electric stimulation or aerobic exercises. All participants were evaluated before the first session of treatment and after 3 months, at the end of the treatment. Normal and fast walk gait speed tests and the Five Times Sit-to-Stand Test and 60 second Sit-to-Stand Test were used to assess participants' physical status. The Restless Legs Syndrome Rating Scale was used to determine the level of restless legs syndrome severity. Results Neuromuscular electric stimulation resulted in significant improvements in all measures of physical performance and in Restless Legs Syndrome Rating Scale score when compared to baseline. Aerobic exercise produced significant improvements in all tests. At the end of the study, aerobic exercise had greater responses than neuromuscular electric stimulation in all parameters measured except the Five Times Sit-to-Stand Test. Conclusions Neuromuscular electrical stimulation may be used as an alternative to aerobic exercise to improve physical performance in cases of less severe restless legs syndrome in those unable or unwilling to participate in physical training.

scholarly journals Translation and validation into the Brazilian Portuguese of the restless legs syndrome rating scale of the International Restless Legs Syndrome Study Group

2008 ◽  
Vol 66 (4) ◽  
pp. 832-836 ◽  
Author(s):  
Alice H. Masuko ◽  
Luciane B.C. Carvalho ◽  
Marco A.C. Machado ◽  
José F. Morais ◽  
Lucila B.F. Prado ◽  
...  
Keyword(s):  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Reliability And Validity ◽  
Brazilian Portuguese ◽  
Motor Disorder ◽  
Study Group ◽  
Alpha Coefficient ◽  
Good Reliability ◽  
Restless Legs ◽  
Translation And Validation

BACKGROUND: Restless legs syndrome (RLS) is a chronic sensory-motor disorder characterized by unpleasant limb sensations and an irresistible urge to move. The International Restless Legs Syndrome Study Group developed the Restless Legs Syndrome Rating Scale (IRLS) to assess the severity of RLS symptoms. The objective of this study was to translate and validate the IRLS into Brazilian Portuguese. METHOD: The IRLS was translated into Brazilian Portuguese, analyzed, back translated to English, and compared to the original version. It was applied to 10 patients for cultural verification. The language was adjusted and the final version was administered to 30 patients (13 male, mean age 58.88±14.82). RESULTS: There was correlation among the IRLS evaluation of three experts. Many linguistic adaptations were required to achieve cultural adequacy and the Cronbach's alpha coefficient showed reliability of 80%. CONCLUSION: IRLS was translated, adapted, and validated to Brazilian Portuguese language, showing good reliability and validity.

scholarly journals AB0715 THE PREVALENCE OF FIBROMIYALGIA IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER AND THE RELATIONSHIP BETWEEN FATIGUE AND QUALITY OF LIFE

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1389.1-1389
Author(s):  
S. Ugurlu ◽  
T. Civi Karaaslan ◽  
Z. Toker Dincer ◽  
E. Tarakci
Keyword(s):  
Quality Of Life ◽  
Familial Mediterranean Fever ◽  
Short Form ◽  
Pearson Correlation ◽  
Fibromyalgia Impact Questionnaire ◽  
Sf 36 ◽  
Mediterranean Fever ◽  
The Mean ◽  
The Relationship

Background:Familial Mediterranean Fever (FMF) can cause various muscle diseases. Because it is a chronic auto inflammatory disease, painful trigger points may be encountered in the examination due to a decrease in the pain threshold (1-3).Objectives:The aim of this study was to determine the prevalence of Fibromiyalgia in patients with FMF, at the same time to identify the relationship between fatigue and quality of life.Methods:Sixtyseven patients (38 female, 29 male) with FMF were enrolled in the study. They were diagnosed with FMF based on the Livneh diagnostic criteria (4). Fibromyalgia involvement of the patients was evaluated according to the Fibromyalgia Impact Questionnaire (FIQ). Patients with diagnose with other chronic disease were excluded. Fatigue Severity Scale (FSS) was used to evaluate fatigue. Quality of life was evaluated with Short Form-36 (SF-36).Results:Respectively, the mean age, disease duration and body mass index were 34.46±12.69 years, 12.66±7.86 years and 24.96±5.42 kg/m2. In addition, 65% of the patients had no rheumatic disease in their family history. The mean of scores of FIQ was 38.66±25.14, the mean of FSS was 38.07±17.56, the mean of SF-36-PCS was 45.55±10.54 and SF36-MCS was 30.93±17.39. Patients were categorized as mild (n=28), moderate (n=24) and severe (n=15) affected according to their FİQ score. The relationships of scores of FIQ, FSS and SF-36 were demonstrated Table 1.Conclusion:Fibromyalgia symptoms can be seen in FMF. According to our results, it has been shown that patients with moderate and severe symptoms have increased fatigue levels and decreased quality of life. In the light of these results, we can say that also the fibromyalgia symptom of patients with FMF should be considered in the treatment.References:[1]Sari, Ismail; Birlik, Merih; Kasifoglu, Timucin. Familial Mediterranean fever: an updated review. European journal of rheumatology, 2014, 1.1: 21.[2]Alayli G, Durmus D, Ozkaya O, Sen HE, Genc G, Kuru O. Frequency of juvenile fibromyalgia syndrome in children with familial Mediterranean fever: effects on depression and quality of life. Clin Exp Rheumatol 2011; 29: S127-32.[3]Langevitz P, Buskila D, Finkelstein R, Zaks N, Neuman L, Sukenik S, et al. Fibromyalgia in familial Mediterranean fever. J Rheumatol 1994; 21: 1335-7.[4]Bashardoust, Bahman. Familial Mediterranean fever; diagnosis, treatment, and complications. Journal of nephropharmacology, 2015, 4.1: 5.Table 1.The correlations of FIQ, FSS and SF-36 scores.FSSSF-36 PCSSF-36 MCSFIQ-mildmean±sd23.78±14.8853.34±7.0140.98±13.73r0.595**-0.014-0.551**p0.0010.9440.002FIQ-moderatemean±sd45.75±10.8341.09±8.8938.13±9.19r0.053-0.379-0.145p0.8060.0680.498FIQ-severemean±sd52.46±10.1138.13±9.1920.32±15.68r0.622*-0.548*-0.268p0.0130.0350.333-Pearson CorrelationDisclosure of Interests:None declared

scholarly journals Evaluation of Adolescents with Restless Legs Syndrome: Relation to School Success

2021 ◽  
pp. 106-110
Author(s):  
Neslihan Günay ◽  
Sevda İsmailoğluları ◽  
Esra Özdemir Demirci ◽  
Fatih Kardaş ◽  
Hüseyin Per
Keyword(s):  
Patient Group ◽  
Restless Legs Syndrome ◽  
School Success ◽  
Rating Scale ◽  
Ferritin Level ◽  
Control Group ◽  
Restless Legs ◽  
Dsm Iv ◽  
The Mean ◽  
Inattention And Hyperactivity

Restless Legs Syndrome (RLS), which may be a missed diagnosis in children, is seen at an important frequency. The aim of this study was to investigate the clinical characteristics of patients with RLS and to show the effect of RLS on school success. Forty-three patients with RLS and 43 healthy volunteers were included to the study. Blood samples were taken to measure ferritin. The averages of school exam scores were recorded. The patient group was classified as mild, moderate, severe, and very severe according to the RLS rating scale. The daytime sleepiness was measured by the Epworth Sleepiness Scale (ESS). The"Turgay DSM-IV-Based Child and Adolescent Disruptive Behavioral Disorders Screening and Rating Scale (T-DSM-IV-S)" was completed by parents, and patients' inattention, and hyperactivity-impulsivity scores were compared with the control group. According to the RLS rating scale scores 25.6% (n:11) were evaluated as mild, 60.5% (n:26) were moderate and 14% (n:6) were severe. The mean ferritin level was significantly lower in the patient group. The mean score of inattention and hyperactivity-impulsivity in the patient group to be significantly higher than the control. The mathematics and science course mean grades were significantly lower in the patient group than the controls (66.7±17.7 vs 74.2±11.7). ESS scores were found to be significantly higher in the patient group. In this study, RLS has been found associated with ADHD and iron deficiency, similar to previous studies. There are not many studies on the effects of RLS in children on daily life and this study has objectively shown that RLS reduces patients' school achievement

scholarly journals Anticonvulsants to treat idiopathic restless legs syndrome: systematic review

2008 ◽  
Vol 66 (2b) ◽  
pp. 431-435 ◽  
Author(s):  
Cristiane Fiquene Conti ◽  
Márcio Moysés de Oliveira ◽  
Juliana Spelta Valbuza ◽  
Lucila Bizari F. Prado ◽  
Luciane Bizari Coin de Carvalho ◽  
...  
Keyword(s):  
Systematic Review ◽  
Restless Legs Syndrome ◽  
Scientific Evidence ◽  
Body Part ◽  
The Body ◽  
Motor Disorder ◽  
Double Blind ◽  
Restless Legs ◽  
Anticonvulsant Treatment

BACKGROUND: Restless legs syndrome (RLS) is a sensory motor disorder characterized by a distressing urge to move the legs and sometimes also other parts of the body usually accompanied by a marked sense of discomfort or pain in the leg or other affected body part. Many treatments have been used to minimize the discomfort of the disease, among them the anticonvulsant therapy. AIM: This review aims to evaluate the efficacy and safety of anticonvulsant treatment for idiopathic RLS. METHOD: Systematic review of randomized or quasi-randomized, double blind trials on anticonvulsant treatment for RLS. Outcomes: relief of RLS symptoms, subjective and objective sleep quality, quality of life, and adverse events associated with the treatments. RESULTS: A total of 231 patients were randomized in three cross over studies and one parallel study. Three studies with carbamazepine, one with sodium valproate, and one with gabapentin, and they were very heterogeneous so we could not perform a metanalyses. CONCLUSIONS: There is no scientific evidence on RLS treatment with anticonvulsants for clinical practice.

Is restless legs syndrome in Parkinson disease patients associated with any specific factor?

2021 ◽  
Vol 79 (1) ◽  
pp. 38-43
Author(s):  
Manoel Alves SOBREIRA-NETO ◽  
Márcio Alexandre PENA-PEREIRA ◽  
Emmanuelle Silva Tavares SOBREIRA ◽  
Marcos Hortes Nisihara CHAGAS ◽  
Carlos Maurício Oliveira de ALMEIDA ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Lower Limbs ◽  
Specific Factor ◽  
Cross Sectional ◽  
Restless Legs

ABSTRACT Background: Restless legs syndrome or Willis-Ekbom disease is a disorder characterized by unpleasant sensations associated with the need to mobilize the lower limbs. In Parkinson disease patients, restless legs syndrome is associated with worse quality of life and excessive sleepiness. Regarding other factors, results of different studies are controversial. Objective: To determine the factors associated with the restless legs syndrome presence in Parkinson disease patients. Methods: A cross-sectional study was conducted in 88 consecutive Parkinson disease patients from the outpatient clinic for 21 months. Participants underwent a clinical interview, assessment based on standardized scales (Epworth Sleepiness Scale, Parkinson Disease Questionnaire - 39, Pittsburgh Sleep Quality Index, International Restless Legs Syndrome Study Group rating scale), and video-polysomnography. Results: Out of the 88 participants, 25 had restless legs syndrome. In the multivariate analysis, restless legs syndrome in Parkinson disease has been associated with the symptom of smell loss and quality of sleep and life. In the univariate analysis, restless legs syndrome in Parkinson disease has occurred more frequently in women with higher frequency of insomnia, constipation, and anosmia than in the group without restless legs syndrome. Conclusion: Restless legs syndrome is a prevalent condition in patients with Parkinson disease and is associated with specific characteristics in this group of patients.

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