scholarly journals Understanding the impact of diet and nutrition on symptoms of Tourette syndrome: A scoping review

2017 ◽  
Vol 22 (1) ◽  
pp. 68-83 ◽  
Author(s):  
Amanda K Ludlow ◽  
Samantha L Rogers

Anecdotal reports frequently suggest some dietary involvement in the maintenance of tics in children with Tourette syndrome (TS). This scoping review aimed to (1) understand the possible influence of diet as a trigger of tics and (2) map out the existing studies documenting dietary interventions in children with TS. Current evidence suggests no single diet to benefit individuals with TS. However, reports from parents of children with TS suggest that certain allergens in food may exacerbate tic-related symptoms. For example, an increase in tics has been related to the consumption of caffeine and refined sugar. Moreover, oligoantigenic diets and sugar-free diets have been identified as significantly reducing tics. More research is urgently needed to develop more accurate guidance for parents and children with TS, as many have reported using dietary and nutritional supplements, despite the lack of evidence detailing any benefits, side effects and recommended doses.

2021 ◽  
Vol 75 (Supplement_2) ◽  
pp. 7512515329p1-7512515329p1
Author(s):  
Rebecca Mariel Rutta ◽  
Shamta Kumar ◽  
Varada Pisharody ◽  
Kaitlyn Cecilia Irwin ◽  
Nancy Baker ◽  
...  

Abstract Date Presented Accepted for AOTA INSPIRE 2021 but unable to be presented due to online event limitations. Executive functions, including attention and regulation, are relevant to successful participation in complex occupations. A scoping review was conducted to summarize and evaluate current evidence for the impact of mindfulness on the attention and regulation skills of preadolescents and adolescents. Findings suggest early promise of mindfulness interventions in improving these skills in the target population. However, firm conclusions cannot be drawn due to low trustworthiness of the evidence. Primary Author and Speaker: Rebecca Mariel Rutta Additional Authors and Speakers: Shamta Kumar, Varada Pisharody, and Kaitlyn Cecilia Irwin Contributing Authors: Nancy Baker, Elizabeth Marfeo, and Margaret Morris


2017 ◽  
Vol 24 (4) ◽  
pp. 305-311 ◽  
Author(s):  
Sara F Jacoby ◽  
Laura M Mercer Kollar ◽  
Greg Ridgeway ◽  
Steven A Sumner

BackgroundHealthcare providers and law enforcement (LE) officers are among the most common first responders to injuring events. Despite frequent interface between the health system (HS) and LE sectors, the published evidence that supports their collaboration in injury surveillance, control and prevention has not been comprehensively reviewed.MethodsWe conducted a scoping review of literature published from 1990 to 2016 that focused on local and regional HS and LE collaborations in injury surveillance, control and prevention. Our aim was to describe what is known and what remains unexplored about these cross-sector efforts.Results128 articles were included in the final review. These were categorised by their focus on either surveillance activities or partnerships in injury control and prevention programmes. The majority of surveillance articles focused on road traffic injuries. Conversely, articles describing partnerships and programme evaluations primarily targeted the prevention of interpersonal violence.DiscussionThis review yielded two major findings: overall, the combination of HS and LE injury data added value to surveillance systems, especially as HS data augmented LE data; and HS and LE partnerships have been developed to improve injury control and prevention. However, there are few studies that have evaluated the impact and sustainability of these partnerships.ConclusionsThe current evidence to support HS and LE collaboration in injury surveillance and control and prevention programmes is heterogeneous. Notable gaps suggest ample opportunity for further research and programme evaluation across all types of injury.


2021 ◽  
Author(s):  
Janet A Curran ◽  
Justine Dol ◽  
Leah Boulos ◽  
Mari Somerville ◽  
Bearach Reynolds ◽  
...  

Background: As of April 2021, three SARS-CoV-2 variants of concern (VOC: B.1.1.7, B.1.351 and P.1) have been detected in over 132 countries. Increased transmissibility of VOC has implications for public health measures and health system arrangements. This rapid scoping review aims to provide a synthesis of current evidence related to public health measures and health system arrangements associated with VOC. Methods: Rapid scoping review. Seven databases were searched up to April 7, 2021 for terms related to VOC, transmission, public health and health systems. A grey literature search was conducted up to April 14, 2021. Title, abstracts and full text were screened independently by two reviewers. Data were double extracted using a standardized form. Studies were included if they reported on at least one of the VOC and public health or health system outcomes. Results: Of the 2487 articles and 59 grey literature sources retrieved, 37 studies and 21 guidance documents were included. Included studies used a wide range of designs and methods. Most of the studies and guidance documents reported on B.1.1.7, and 18 studies and 4 reports provided data for consideration in relation to public health measures. Public health measures, including lockdowns, physical distancing, testing and contact tracing, were identified as critical adjuncts to a comprehensive vaccination campaign. No studies reported on handwashing or masking procedures related to VOC. For health system arrangements, 17 studies were identified. Some studies found an increase in hospitalization due to B.1.1.7 but no difference in length of stay or ICU admission. Six studies found an increased risk of death ranging from 15-67% with B.1.1.7 compared non-B.1.1.7, but three studies reported no change. One study reported on the effectiveness of personal protective equipment in reducing VOC transmission in the hospital. No studies reported on screening staff and visitors, adjusting service provisions, or adjusting patient accommodations and shared spaces, which is a significant gap in the literature. Guidance documents did not tend to cite any evidence and were thus assumed to be based on expert opinion. Conclusion: While the findings should be interpreted with caution as most of the sources identified were preprints, findings suggest a combination of non-pharmaceutical interventions (e.g., masking, physical distancing, lockdowns, testing) should be employed alongside a vaccine strategy to improve population and health system outcomes. While the findings are mixed on the impact of VOC on health system arrangements, the evidence is trending towards increased hospitalization and death.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Nandita Perumal ◽  
Beverly Bradley ◽  
Aviva Rappaport ◽  
Vanessa Pike ◽  
Stanley Zlotkin

Abstract Objectives To summarize the evidence on the impact of nutrition policies on improving health among children in low-, middle- and high-income countries (LMHICs). Methods A scoping review was conducted to map and describe peer-reviewed studies evaluating the impact of population-level nutrition policies on child health and undernutrition (using primary data) in LMHICs. We systematically searched Medline, Embase, Web of Science, Scopus, and PAIS Index for public policy, to identify eligible studies. Data on key study characteristics, including research design, type of nutrition policy, time span of policy, child's age at outcome assessment, and types of outcomes assessed, were abstracted. Abstract screening and data abstraction were conducted in duplicate and reconciled. Results Of the 5646 abstracts screened, 83 studies were included. The majority of studies were conducted in upper-middle or high-income settings (66%, 54/83 studies) (Figure 1). Most studies were observational study design (49%, 41/83 studies), evaluated regional/sub-national policies (68%, 56/83 studies), reported on mandatory policies (71%, 59/83 studies), were related to micronutrient food fortification and/or supplementation (70%, 58/83 studies), and assessed outcomes among children <5 years of age (55%, 46/83 studies). Iodine deficiency disorders (40%, 33 studies) and neural tube defects (18%, 15 studies) were the most commonly assessed child health outcomes. The impact of policy intervention on outcomes, such as low birth weight, breastfeeding rates, vitamin A deficiencies, and child growth, were assessed less frequently. Policies were largely implemented between 1990–2000 (36%, 30/83 studies) and studies mostly evaluated effects within a year (28%, 23/83) or within 2–5 years since policy implementation (13%, 11/83 studies). Conclusions Among the studies reviewed, nutrition policies were commonly associated with improved child nutrition and health. However, current evidence is primarily based on regional studies from high-income settings evaluating the effect of micronutrient food fortification and/or supplementation policies on a narrow set of outcomes. Further research is needed to assess the impact of a broader range of nutrition policies on child health, particularly in LMICs. Funding Sources Funding for this research was provided by the 2017 SickKids Centre for Global Child Health Catalyst Grant Competition. Supporting Tables, Images and/or Graphs


2013 ◽  
Vol 27 (1) ◽  
pp. 83-93 ◽  
Author(s):  
Andrea Eugenio Cavanna ◽  
Kate David ◽  
Valentina Bandera ◽  
Cristiano Termine ◽  
Umberto Balottin ◽  
...  

Gilles de la Tourette syndrome (GTS) is a neurodevelopmental condition characterised by multiple motor and phonic tics and associated behavioural problems, carrying a significant burden on patients' lives. Although the term health related-quality of life (HR-QOL) has only been used in recent years, several studies have long addressed the impact of GTS on physical, psychological and social aspects of wellbeing of both children and adults with GTS. We set out to answer the question "Is HR-QOL affected by GTS and, if so, in what domains?" by conducting a systematic literature review of published original studies addressing HR-QOL in both children and adult patients with GTS. This review focuses on the current evidence on the impact of GTS on patients' lives, mainly informed by studies using generic functional impairment and HR-QOL measures from the last decade, and expands on the new opportunities introduced by the recently developed GTS-specific HR-QOL scales (GTS-QOL and GTS-QOL-C&A). Analysis of the first decade of studies specifically addressing HR-QOL in GTS suggests that co-morbid conditions are key factors in determining HR-QOL in young patients, whilst the picture is more complex in adults with GTS. These findings offer some general directions for both current clinical practice and future research.


2014 ◽  
Vol 2 (20) ◽  
pp. 1-196 ◽  
Author(s):  
Yvonne Birks ◽  
Reema Harrison ◽  
Kate Bosanquet ◽  
Jill Hall ◽  
Melissa Harden ◽  
...  

BackgroundIn 2009 the UK National Patient Safety Agency relaunched its Being Open framework to facilitate the open disclosure of adverse events to patients in the NHS. The implementation of the framework has been, and remains, challenging in practice.AimThe aim of this work was to both critically evaluate and extend the current evidence base relating to open disclosure, with a view to supporting the implementation of a policy of open disclosure of adverse events in the NHS.MethodsThis work was conducted in three phases. The first phase comprised two focused systematic literature reviews, one summarising empirical research on the effectiveness of interventions to enhance open disclosure, and a second, broader scoping review, looking at reports of current opinion and practice and wider knowledge. The second phase involved primary qualitative research with the objective of generating new knowledge about UK-based stakeholders’ views on their role in and experiences of open disclosure. Stakeholder interviews were analysed using the framework approach. The third phase synthesised the findings from the first two phases to inform and develop a set of short pragmatic suggestions for NHS trust management, to facilitate the implementation and evaluation of open disclosure.ResultsA total of 610 papers met the inclusion criteria for the broad review. A large body of literature discussed open disclosure from a number of related, but sometimes conflicted, perspectives. Evidential gaps persist and current practice is based largely on expert consensus rather than evidence. There appears to be a tension between the existing pragmatic guidance and the more in-depth critiques of what being consistent and transparent in health care really means. Eleven papers met the inclusion criteria for the more focused review. There was little evidence for the effectiveness of disclosure alone on organisational or individual outcomes or of interventions to promote and support open disclosure. Interviews with stakeholders identified strong support for the basic principle of being honest with patients or relatives when someone was seriously harmed by health care. In practice however, the issues are complex and there is confusion about a number of issues relating to disclosure policies in the UK. The interviews generated insights into the difficulties perceived within health care at individual and institutional levels, in relation to fully implementing the Being Open guidance.ConclusionsThere are several clear strategies that the NHS could learn from to implement and sustain a policy of openness. Literature reviews and stakeholder accounts both identified the potential benefits of a culture that was generally more open (not just retrospectively open about serious harm). Future work could usefully evaluate the impact of disclosure on legal challenges within the NHS, best practice in models of support and training for open disclosure, embedding disclosure conversations in critical incident analysis and disclosure of less serious events.FundingThe National Institute for Health Research Health Services and Delivery Research programme.


PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254222
Author(s):  
Michael Hoffer-Hawlik ◽  
Andrew Moran ◽  
Lillian Zerihun ◽  
John Usseglio ◽  
Jennifer Cohn ◽  
...  

Hypertension remains the leading cause of cardiovascular disease worldwide and disproportionately impacts patients living in low- and middle-income countries (LMICs). Telemedicine offers a potential solution for improving access to health care for vulnerable patients in LMICs. Objectives The purpose of this scoping review was to summarize the evidence for telemedicine interventions for blood pressure management in LMICs and assess the relationships between the telemedicine intervention characteristics and clinical outcomes. Design Published studies were identified from the following databases (from their inception to May 2020): PubMed, Scopus, and Embase. Search terms related to “Low and Middle Income Countries,” “Telemedicine,” and “Hypertension” were used, and clinical outcomes were extracted from the screened articles. Results Our search resulted in 530 unique articles, and 14 studies were included in this review. Five studies assessed telemedicine interventions for patient-provider behavioral counseling, four assessed patient-provider medical management, and five assessed provider-provider consultation technologies. Out of fourteen individual studies, eleven demonstrated a significant improvement in systolic or diastolic blood pressure in the intervention group. Of the eight studies that reported difference-in-differences changes in systolic blood pressure, between-arm differences ranged from 13.2 mmHg to 0.4 mmHg. Conclusions The majority of the studies in this review demonstrated a significant reduction in blood pressure with use of the telemedicine intervention, though the magnitude of benefit was not consistently large. Limitations of the studies included small sample sizes, short duration, and intervention heterogeneity. Current evidence suggests that telemedicine may provide a promising approach to increase access to care and improve outcomes for hypertension in LMICs, especially during events that limit access to in-person care, such as the COVID-19 pandemic. However, high-quality clinical trials of sufficient size and duration are needed to establish the impact and role of telemedicine in hypertension care. The protocol for this review was not registered.


2020 ◽  
Vol 29 (1S) ◽  
pp. 530-559
Author(s):  
Julie Hickin ◽  
Madeline Cruice ◽  
Lucy Dipper

Purpose Aphasia research demonstrates increasing interest in the treatment of verb retrieval deficits. This systematically conducted scoping review reports on the level and fidelity of the current evidence for verb treatments; on its effectiveness regarding the production of trained and untrained verbs, functional communication, sentences, and discourse; and on the potential active ingredients. Recommendations to guide clinical decision making and future research are made. Method The computerized database search included studies from January 1980 to September 2018. The level of evidence of each study was documented, as was fidelity in terms of treatment delivery, enactment, and receipt. Studies were also categorized according to the treatment methods used. Results Thirty-seven studies were accepted into the review, and all but 1 constituted a low level of evidence. Thirty-three studies (89%) described treatment in sufficient detail to allow replication, dosage was poorly reported, and the fidelity of treatment was rarely assessed. The most commonly reported treatment techniques were phonological and semantic cueing in 25 (67.5%) and 20 (54%) studies, respectively. Retrieval of trained verbs improved for 80% of participants, and improvements generalized to untrained verbs for 15% of participants. There was not sufficient detail to evaluate the impact of treatment on sentence production, functional communication, and discourse. Conclusions The evidence for verb treatments is predominantly of a low level. There are encouraging findings in terms of treatments being replicable; however, this is tempered by poor monitoring of treatment fidelity. The quality of verb treatment research would be improved by researchers reaching consensus regarding outcome measures (including generalization to, e.g., sentences and discourse) by manualizing treatment to facilitate implementation and exploring the opinions of participants. Finally, while treatment is largely effective in improving production of trained verbs, lack of generalization to untrained items leads to the recommendation that personally relevant verbs are prioritized.


Geriatrics ◽  
2021 ◽  
Vol 6 (4) ◽  
pp. 96
Author(s):  
Abu Baker Sheikh ◽  
Nismat Javed ◽  
Katarina Leyba ◽  
Ali Hamza Khair ◽  
Zainab Ijaz ◽  
...  

Delirium leading to agitation is a common issue in elderly people and patients with underlying neurocognitive impairment. Despite use of medications to treat agitation, polypharmacy is a major concern and might lead to multiple side effects in this patient population. Therefore, it is imperative to investigate non-pharmacological methods that can provide solutions to the problem. The objective of this review was to evaluate the impact of pet-assisted therapy on elderly patients, with a major focus on agitation and delirium. For the purposes of this study, a scoping review was performed using PubMed, Google Scholar, and ClinicalTrials. We reviewed literature from 1980 to 2021. Out of the 31 studies reviewed, 14 commented on agitation with respect to pet-assisted interventions. Of these, eight studies (57%) reported a statistically significant reduction in agitation and/or delirium in patients who were exposed to pet therapy. Pet-assisted therapy can improve the standardized care in hospital-based settings for patients with neurocognitive impairment because of better companionship, reduced agitation and mood disorders, and better stability of hemodynamic status. These interventions can pave the way for better patient and hospital satisfaction.


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