scholarly journals Childhood with a relative's excessive alcohol use, and own drinking in adult years

2021 ◽  
pp. 145507252110507
Author(s):  
Jóna Ólafsdóttir ◽  
Sindri Steinn Marinósson

Objective: The aim of this study was to investigate if individuals who had been brought up by relatives (e.g. parents, siblings and grandparents) who consumed excessive alcohol effected these individuals' own alcohol use in their adult years. The participants in the study were also asked about their alcohol consumption in the past 12 months, and abstainers were asked about their reasons for choosing to live their lives without consuming alcohol. Method: A quantitative approach was used. Data collected from the Icelandic RARHA SEAS were used in this study. A panel of 2500 respondents in the age range of 18-65 years was randomly sampled and was intended to be adequately representative of the Icelandic population. There was a 34.9% response rate ( n=873). Results: Of the 873 source of this study, 26.6% (n=211) categorised as Group A had lived with relatives who excessively consumed alcohol, and this had negatively affected them in their childhood. In their adult years, Group A seemed to be more frequently intoxicated than the control group, Group B (n=659). They also experienced more negative consequences from their alcohol consumption. Group A was likely to consume alcohol to deal with difficult feelings such as depression, and they were also more likely to abstain than Group B. Conclusions: The childhood experience of living with relatives who excessively use alcohol does not impact everyone in the same way in their adult years. Some of them are more likely to use excessive alcohol as adults without relating it to their childhood experience of relatives excessively using alcohol.

2015 ◽  
Vol 11 (3) ◽  
pp. 158-168
Author(s):  
Montana Hewlett ◽  
Lisa Merry ◽  
Anit Mishra ◽  
Risatul Islam ◽  
Raz Mohammad Wali ◽  
...  

Purpose – The purpose of this paper is to explore factors associated with alcohol use disorders (AUDs) among Bhutanese refugees in Nepal, where there has been a mass third-country resettlement operation in place since 2007. Design/methodology/approach – A case-control study was conducted in which the Alcohol Use Disorder Identification Test (AUDIT) was used to confirm AUDs and participants’ eligibility for placement in a case or control group. A translated questionnaire measuring demographic variables and context of drinking was also administered. Findings – In total, 128 questionnaires were completed (32 cases, 96 controls). Compared to participants without AUDs, those with AUDs were more likely to be older (36-50 years) (OR=10.5, 95 per cent CI 2.17-50.81), (50+years) (OR=10.3, 95 per cent CI 2.02-52.71), illiterate (OR=7.3 (2.80-18.42)), use tobacco (smoking or chewing) (OR=4.3 (1.84-10.01)) and be male (OR=3.5 (1.35-8.67)). Reasons for excessive alcohol use included unemployment, unoccupied time and increased family tensions. Originality/value – The study is the first of which the authors are aware that attempts to examine risk factors associated with AUDs within the context of a mass resettlement operation where camp services are winding down. The findings of this study suggest that greater attention needs to be given toward creating meaningful activities for adult, less educated male migrants awaiting resettlement.


2021 ◽  
Vol 12 (1) ◽  
pp. 774-785
Author(s):  
Meenakshi S ◽  
Indu Thammaiah ◽  
Anil Kumar G ◽  
Sahana K

Speech is an autonomous and unconscious activity. Its production involves a combination of phonation and articulation. Thus the aim of the study is to evaluate and compare linguo palatal sounds /ţ/, /d/, /tᶴ^/and /ᶴ^/ in three different groups like Group A individual with conventional complete dentures without palatine rugae, group B individual with conventional complete dentures with palatine rugae and Group C normal dentition individuals. A total of 20 individuals completely edentulous were selected in the age range of 50 to 65 years for the study. Control group consisted of10 individuals, with complete natural dentition in the same age group.4 Linguo-palatal phonemes in Kannada like /ţ/, /d/, /tᶴ^/and /ᶴ^/ were considered for the study and the target phonemes were identified in the initial and medial position of words of Kannada Articulation Test. The speech samples with target phonemes were analysed perceptually and acoustically by SLP software. Spectral parameters and temporal parameters were better in with palatal rugae denture than compared to without palatal rugae. Perceptual analysis reports showed many substitution errors with a conventional denture. To summarize, with customized rugae denture speech was clearer. To conclude, speech characteristic will be better after denture insertion compared to the edentulous stage.


2009 ◽  
Vol 1 (1) ◽  
pp. 15
Author(s):  
Sabina Yeasmin ◽  
Noorzahan Begum ◽  
Shelina Begum

<p><strong>Background</strong>: Hypothyroidism is a clinical condition associated with low levels of thyroid hormones with raised TSH. Peripheral neuropathy may be associated with hypothyroidism which usually develops insidiously over a long period of time due to irregular taking of drugs or lack of thyroid hormone replacement.</p> <p><strong>Objectives: </strong>The present study was done to evaluate the clinical and electro-physiological findings in hypothyroid patients in order to evaluate the neuromuscular dysfunction as well as motor neuropathy.</p> <p><strong>Method: </strong>In this study, 70 subjects with the age range from 20 to 50 years of both sexes were included of whom 40 hypothyroids were taken in study group (B) with the duration of 6 months to 5 years and 30 healthy euthyroid subjects were taken as control (Group A). On the basis of their TSH level, group B was further divided into group B<sub>1</sub> with TSH level &lt;60 MIU /L (less severe) and group B<sub>2</sub> with TSH &gt;60 MIU /L (severe group). The d latency and NCV for motor nerve function were measured by NCV machine in median and ulnar nerve for upper limb and in common peroneal nerve for lower limb. TT<sub>3</sub>, TT<sub>4</sub> were measured by RIA and TSH by IRMA method. All these parameters were measured on the day 1 (one) of their first visit. Data were analysed statistically by ANOVA and Z test.</p> <p><strong>Result: </strong>Both TT<sub>3</sub>, TT<sub>4</sub> levels were significantly (P&lt;0.01) lower in hypothyroids in comparison to those of control. Diminished or absence of most of the deep tendon reflexes were found in all the hypothyroids. Most of the patients (67.5%) showed significantly higher (P &lt;0.01) motor distal latencies (MDL) with lower (P&gt; 0.001) conduction velocities (MNCV) and all these changes were more marked in group B<sub>2</sub>.</p> <p><strong>Conclusion: </strong>So, the study revealed that motor neuropathy may be a consequence of hypothyroidism.</p><p>DOI: 10.3329/bsmmuj.v1i1.3692</p> <p><strong>Key Words: </strong>Hypothyroidism; neuropathy; electrophysiology</p> <p><em>BSMMU J </em>2008; 1(1): 15-18</p>


2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.


Author(s):  
Patil Aniket ◽  
Dindore Pallavi ◽  
Arbar Aziz ◽  
Kadam Avinash ◽  
Saroch Vikas

The quest for excellence in mental and physical health is not new. We find various references and formulations in Ayurvedic classics meant for promoting mental and physical health of a child. Suvarna Prashan is one of the formulations explained in age old Ayurvedic classic Kashyap Samhita. This formulation is very widely used now days as a memory and immune booster for children. But there is very little systematic documented study which can be used to evaluate the efficacy of the formulation. Suvarna Bhasma was prepared in Ayurved Rasayani Pharmacy, Pune. Madhu and Ghrita were collected from KLE Ayurveda Pharmacy, Belgaum. Suvarna Bindu Prashan was prepared in KLE Ayurved pharmacy, Belgaum. It contains Suvarna Bhasma, Ghrita and Madhu. Twenty apparently healthy male and female children with age group of three to four years were ready to sign inform consent form were selected into two groups each. Subjects in Group A received Suvarna Bindu Prashan where as Group B (Control group) did not receive any treatment. Both the groups were observed for six months. Children in Suvarna Bindu Prashan group showed significant reduction in the scores of eating habits, behavior, mood, temperament and scores of event of illness. However there was no significant difference in the score of sleeping habit. There was significant increase in IQ percentage.


2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Jianguo Liu ◽  
Liehui Xiao ◽  
Hezhongrong Nie ◽  
Yong Pan ◽  
Yan Liu ◽  
...  

Abstract Objective To investigate the impact of microecological preparation combined with modified low-carbon diet on the glucolipid metabolism and cardiovascular complication in obese patients. Methods From August 2017 to July 2020, 66 obese patients were recruited, and administrated with an modified low-carbon diet with (group A) or without (Group B) microecology preparation and a balanced diet in control group (group C) for 6 months. Meanwhile, 20 volunteers administrated with a balanced diet were recruited as the healthy control group (group D). Results After 6-month intervention, obese subjects in group A and B showed significant improvement of body and liver fat mass, reduction of serum lipid levels, intestinal barrier function markers, insulin resistance index (IRI), high blood pressure (HBP) and carotid intima thickness, as compared with subjects in group C. More importantly, subjects in group A had better improvement of vascular endothelial elasticity and intimal thickness than subjects in group B. However, these intervention had no effect on carotid atherosclerotic plaque. Conclusion Administration of microecological preparation combined with modified low-carbon diet had better improvement of intestinal barrier function, glucose and lipid metabolism, and cardiovascular complications than low-carbon diet in obese patients, but the effect of a simple low-carb diet on carotid atherosclerotic plaque need to be further addressed.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guanyu Yang ◽  
Zefei Zhu ◽  
Hongyu Zheng ◽  
Shifeng He ◽  
Wanyue Zhang ◽  
...  

Abstract Background This study explored the comparison of the thermal insulation effect of incubator to infusion thermometer in laparoscopic hysterectomy. Methods We assigned 75 patients enrolled in the study randomly to three groups: Group A: Used warming blanket; group B: Used warming blanket and infusion thermometer; group C: Used warming blanket and incubator. The nasopharyngeal temperature at different time points during the operation served as the primary outcome. Results The nasopharyngeal temperature of the infusion heating group was significantly higher than that of the incubator group 60 min from the beginning of surgery (T3): 36.10 ± 0.20 vs 35.81 ± 0.20 (P<0.001)90 min from the beginning of surgery (T4): 36.35 ± 0.20 vs 35.85 ± 0.17 (P<0.001). Besides, the nasopharyngeal temperature of the incubator group was significantly higher compared to that of the control group 60 min from the beginning of surgery (T3): 35.81 ± 0.20 vs 35.62 ± 0.18 (P<0.001); 90 min from the beginning of surgery (T4): 35.85 ± 0.17 vs 35.60 ± 0.17 (P<0.001). Regarding the wake-up time, that of the control group was significantly higher compared to the infusion heating group: 24 ± 4 vs 21 ± 4 (P = 0.004) and the incubator group: 24 ± 4 vs 22 ± 4 (P = 0.035). Conclusion Warming blanket (38 °C) combined infusion thermometer (37 °C) provides better perioperative thermal insulation. Hospitals without an infusion thermometer can opt for an incubator as a substitute. Trial registration This trial was registered with ChiCTR2000039162, 20 October 2020.


Biology ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 12
Author(s):  
David Chavarri-Prado ◽  
Aritza Brizuela-Velasco ◽  
Ángel Álvarez-Arenal ◽  
Markel Dieguez-Pereira ◽  
Esteban Pérez-Pevida ◽  
...  

Objectives: To determine the effect of mechanical loading of bone on the stability and histomorphometric variables of the osseointegration of dental implants using an experimental test in an animal model. Materials and Methods: A total of 4 human implants were placed in both tibiae of 10 New Zealand rabbits (n = 40). A 6-week osseointegration was considered, and the rabbits were randomly assigned to two groups: Group A (Test group) included 5 rabbits that ran on a treadmill for 20 min daily during the osseointegration period; Group B (Controls) included the other 5 that were housed conventionally. The monitored variables were related to the primary and secondary stability of the dental implants (implant stability quotient—ISQ), vertical bone growth, bone to implant contact (BIC), area of regenerated bone and the percentage of immature matrix. Results: The results of the study show a greater vertical bone growth (Group A 1.26 ± 0.48 mm, Group B 0.32 ± 0.47 mm, p < 0.001), higher ISQ values (Group A 11.25 ± 6.10 ISQ, 15.73%; Group B 5.80 ± 5.97 ISQ, 7.99%, p = 0.006) and a higher BIC (Group A 19.37%, Group B 23.60%, p = 0.0058) for implants in the test group, with statistically significant differences. A higher percentage of immature bone matrix was observed for implants in the control group (20.68 ± 9.53) than those in the test group (15.38 ± 8.84) (p = 0.108). A larger area of regenerated bone was also observed for the test implants (Group A 280.50 ± 125.40 mm2, Group B 228.00 ± 141.40 mm2), but it was not statistically significant (p = 0.121). Conclusions: The mechanical loading of bone improves the stability and the histomorphometric variables of the osseointegration of dental implants.


Author(s):  
Akinleye Stephen Akinrinde ◽  
Halimot Olawalarami Hameed

Abstract Objectives This study examined the possible protective roles of exogenous glycine (Gly) and L-Arginine (l-Arg) against Diclofenac (DIC)-induced gastro-duodenal damage in rats. Methods Rats were divided into Group A (control), Group B (DIC group) and Groups C–F which were pre-treated for five days with Gly1 (250 mg/kg), Gly2 (500 mg/kg), l-Arg1 (200 mg/kg) and l-Arg2 (400 mg/kg), respectively, before co-treatment with DIC for another three days. Hematological, biochemical and histopathological analyses were then carried out. Results DIC produced significant (p<0.05) reduction in PCV (13.82%), Hb (46.58%), RBC (30.53%), serum total protein (32.72%), albumin (28.44%) and globulin (38.01%) along with significant (p<0.05) elevation of serum MPO activity (83.30%), when compared with control. In addition, DIC increased gastric H2O2 and MDA levels by 33.93 and 48.59%, respectively, while the duodenal levels of the same parameters increased by 19.43 and 85.56%, respectively. Moreover, SOD, GPx and GST activities in the DIC group were significantly (p<0.05) reduced in the stomach (21.12, 24.35 and 51.28%, respectively) and duodenum (30.59, 16.35 and 37.90%, respectively), compared to control. Treatment with Gly and l-Arg resulted in significant amelioration of the DIC-induced alterations although l-Arg produced better amelioration of RBC (29.78%), total protein (10.12%), albumin (9.93%) and MPO (65.01%), compared to the DIC group. The protective effects of both amino acids against oxidative stress parameters and histological lesions were largely similar. Conclusions The data from this study suggest that Gly or l-Arg prevented DIC-induced gastro-duodenal toxicity and might, therefore be useful in improving the therapeutic index of DIC.


Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 277
Author(s):  
Raluca Cosgarea ◽  
Sigrun Eick ◽  
Ionela Batori-Andronescu ◽  
Søren Jepsen ◽  
Nicole B. Arweiler ◽  
...  

The aim of this study was to evaluate the clinical and microbiological effects of subgingival instrumentation (SI) alone or combined with either local drug delivery (LDD) or photodynamic therapy (PDT) in persistent/recurrent pockets in patients enrolled in supportive periodontal therapy (SPT). A total of 105 patients enrolled in SPT were randomly treated as follows: group A (n = 35): SI +PDT and 7 days later 2nd PDT; group B (n = 35): SI+LDD; group C (n = 35): SI (control). Prior intervention, at 3 and 6 months after therapy, probing pocket depths, clinical attachment level, number of treated sites with bleeding on probing (n BOP), full mouth plaque and bleeding scores (gingival bleeding index, %BOP) were recorded. At the same time points, 8 periodontopathogens were quantitatively determined. All three treatments resulted in statistically significant improvements (p < 0.05) of all clinical parameters without statistically significant intergroup differences (p > 0.05). Several bacterial species were reduced in both test groups, with statistically significantly higher reductions for LDD compared to PDT and the control group. In conclusion, the present data indicate that: (a) In periodontal patients enrolled in SPT, treatment of persistent/recurrent pockets with SI alone or combined with either PDT or LDD may lead to comparable clinical improvements and (b) the adjunctive use of LDD appears to provide better microbiological improvements for some periodontal pathogens than SI alone or combined with PDT.


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