scholarly journals A Study of Risk Factors for Early-Onset Adjacent Vertebral Fractures After Kyphoplasty

2019 ◽  
Vol 10 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Masayoshi Morozumi ◽  
Yuji Matsubara ◽  
Akio Muramoto ◽  
Yoshinori Morita ◽  
Kei Ando ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Onset ◽  
Odds Ratio ◽  
Multivariate Analyses ◽  
Thoracolumbar Junction ◽  
Spinal Level ◽  
Related Factors ◽  
Adjacent Vertebral Fracture ◽  
Vertebral Bodies ◽  
Risks Factors

Study Design: Retrospective study. Objectives: To elucidate risk factors for early-onset (2 months after initial kyphoplasty) adjacent vertebral fracture (EO-AVF) after kyphoplasty. Methods: A total of 108 vertebral bodies (95 patients) were included in this study. We examined patient backgrounds, the spinal level of EO-AVFs, surgery-related factors, and imaging findings. We divided the cases into 2 groups: patients with EO-AVF and patients without EO-AVF. Univariate, correlation, and multivariate analyses were conducted to reveal the risks factors for EO-AVFs for these 2 groups. Results: EO-AVFs developed in 28 vertebral bodies; they did not develop in 80 vertebral bodies. The overall EO-AVF incidence rate was 26%. The spinal level was the thoracolumbar junction for 93% of patients and another level for 7%, thus demonstrating the concentration of EO-AVFs in the thoracolumbar junction. For patients without EO-AVF and those with EO-AVF, there were significant differences in age (76 and 80 years, respectively), preoperative vertebral angles (VAs) (17.8° and 23°, respectively), and corrected VAs (7.3° and 12.7°, respectively). Significant differences were not observed for other factors. Pearson’s correlation coefficient was 0.661 ( P < .000), thereby showing a significantly positive correlation between preoperative VAs and corrected VAs. Logistic regression analysis indicated that age (odds ratio, 1.112; 95% CI, 1.025-1.206) and preoperative VAs (odds ratio, 1.08; 95% CI, 1.026-1.135) were covariates and that the presence of an EO-AVF was a dependent variable. Therefore, both were predictable risk factors for EO-AVFs. Conclusion: Age, preoperative VAs, and corrected VAs are risk factors for EO-AVFs after kyphoplasty.

Abstract WP164: Role of Risk Factors in the Paradoxical Effect of Smoking on Peri-procedural Stroke in SAMMPRIS

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Christine A Holmstedt ◽  
Tanya N Turan ◽  
Michael J Lynn ◽  
Bethany F Lane ◽  
Jean Montgomery ◽  
...  
Keyword(s):  
Risk Factors ◽  
Odds Ratio ◽  
Multivariate Analyses ◽  
Smoking Status ◽  
Active Form ◽  
Intracranial Stenosis ◽  
Contributory Factor ◽  
Increased Risk ◽  
Never Smokers

Background: A previous SAMMPRIS analysis of patients randomized to stenting showed that peri-procedural ischemic infarcts were significantly associated with diabetes, basilar stenosis, age, and smoking status with never smokers having a higher risk (odds ratio = 8.8, p< 0.001). We sought to determine if this finding could be due to a higher burden of other risk factors in never smokers. Method: Baseline features in 213 patients undergoing stenting in SAMMPRIS were compared between never smokers vs. former and current smokers in univariate and multivariate analyses. Logistic regression was used to determine the effect of smoking on peri-procedural ischemic infarcts after adjusting for factors related to smoking. Data: Univariate results are shown in Table 1. Never smokers were significantly (P<0.05) more likely to be female, diabetic, hypertensive, and have another intracranial stenosis, but in multivariate analyses only hypertension and another intracranial stenosis remained significantly (P<0.05) associated with smoking status. In a multivariate model that incorporated hypertension and another intracranial stenosis along with smoking status, diabetes, basilar stenosis, and age, smoking status remained significant with an increased risk among patients who never smoked (odds ratio = 5.3, p = 0.005). Conclusion: While never smokers had significantly higher rates of some risk factors compared to active or previous smokers, these risk factors do not explain all the increased risk of early stroke in never smokers after stenting in SAMMPRIS. Another contributory factor may be that smoking accelerates the conversion of clopidogrel to its active form.

scholarly journals Risk Factors of Poorly Controlled Childhood Epilepsy - A Study in A Tertiary Care Hospital

2012 ◽  
Vol 34 (2) ◽  
pp. 44-50 ◽  
Author(s):  
AKM Moinuddin ◽  
Md Mizanur Rahman ◽  
Shaheen Akhter ◽  
Syeda Tabassum Alam ◽  
CA Kawser
Keyword(s):  
Risk Factors ◽  
Early Onset ◽  
Odds Ratio ◽  
Tertiary Care Hospital ◽  
Focal Epilepsy ◽  
Tertiary Care ◽  
Idiopathic Epilepsy ◽  
Care Hospital ◽  
Hospital Design ◽  
One Year

Objective: Identifying the risk factors of poor seizure control in children in a setting of tertiary care hospital. Design: Retrospective study. Setting: Child Development and Neurology Unit in the department of Paediatrics of Bangabandhu Sheikh Mujib Medical University (BSMMU). Study period: January 2004 through December 2005. Subjects: One hundred and twenty epileptic children were studied. They were grouped into controlled group (seizure free for more than six months) and poorly controlled group (having one or more seizure per month over a period of six months or more and who had experienced trials of at least two different antiepileptic drugs at optimum doses alone or in combination with adequate compliance) at the end of intervention and compared. Results: In this study 76 (63.3%) children were male and 44 (36.7%) children were female. Out of 120 cases 79 (65.8%) were in controlled group and 41 (34.2%) cases had poorly controlled epilepsy. Mean age of the controlled group and poorly controlled group of children were 79 months and 40.3 months respectively. Focal epilepsy was found in 30 (68%) cases in controlled and in 14 (31.8%) cases of poorly controlled group and generalized epilepsy was found in 42 (72%) cases in controlled and in 19 (28.8%) cases in poorly controlled group. Idiopathic epilepsy was more common which was 37 (46%) in controlled group against 14 (34%) in poorly controlled group. But symptomatic and cryptogenic cases were more prevalent with poorly controlled group 57.5% than controlled group 53%. In poorly controlled group 48.8% had cerebral palsy in comparison to 22.8% of controlled group. Early onset of seizure before one year was 25.3% in controlled and 78% in poorly controlled group (odds ratio=.2322, p =.0082) and one or more seizure per week 43% in controlled and 92.7% in poorly controlled group (odds ratio=.1218, p=.0032) were found as risk factors of poorly controlled epilepsy. Conclusion: Early onset of seizure before one year, symptomatic epilepsy and one or more seizure per week at diagnosis were found as risk factors of poorly controlled epilepsy in children attending a tertiary care hospital. DOI: http://dx.doi.org/10.3329/bjch.v34i2.10216 BJCH2010; 34(2): 44-50

Risk-Factors for Acute Graft-Versus-Host Disease and Survival After Hematopoietic Cell Transplantation From Siblings and Unrelated Donors – An Analysis of the CIBMTR

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 897-897
Author(s):  
Madan Jagasia ◽  
Mukta Arora ◽  
Mary Flowers ◽  
Nelson J. Chao ◽  
Philip L. McCarthy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Odds Ratio ◽  
Hematopoietic Cell Transplantation ◽  
Multivariate Analyses ◽  
Graft Versus Host ◽  
Group 4 ◽  
Unrelated Donors ◽  
Independent Risk Factors ◽  
Group 5 ◽  
Lower Odds Ratio

Abstract Abstract 897 Recent changes in allogeneic hematopoietic cell transplantation (HCT) including increased use of reduced-intensity conditioning, peripheral blood cells as the graft source (PB) and unrelated donors (URD) warrant re-evaluation of risk factors for acute graft-versus-host disease (aGVHD) and its impact on overall survival (OS). Risk factors for these outcomes were analyzed using more recent data from CIBMTR observational database. Methods: The cohort included adult patients ≥ 20 y transplanted from an HLA-identical sibling (SD) (n=3191) or URD (N=2370) for acute myelogenous leukemia (AML), acute lymphoid leukemia (ALL), chronic myeloid leukemia (CML), or myelodsyplastic syndrome (MDS) using a T-cell replete graft from 1999–2005. Six groups were created to evaluate the impact of conditioning [(myeloablative (MA) and reduced-intensity or non-myeloablative (RIC)], total-body irradiation (TBI) and graft source [(bone marrow (BM) or PB] as follows: MA+TBI+PB (group 1), MA+TBI+BM (group 2) MA+ no TBI+PB (group 3), MA+ no-TBI+BM (group 4), RIC+PB (group 5) and RIC+BM (group 6). Separate analyses were performed for SD and URD. IBMTR grade was used to classify aGVHD. A p-value of ≤ 0.01 was considered significant. Results: Among the SD cohort, the probability of aGVHD grade B-D and grade C-D at 100 days was 39% (95% CI, 37–41%) and 16% (95% CI, 14–17%). In multivariate analyses, non-TBI based MA regimens with a BM graft (group 4), RIC conditioning with PB (group 5) and tacrolimus plus methotrexate aGVHD prophylaxis were associated with lower odds ratio of grade B-D aGVHD (Table 1). The probability of OS was 51% (95% CI: 49–53%) at 3 y and 46% (95% CI: 44–49%) at 5 y. In multivariate analyses, grade B-D aGVHD was associated with a higher risk of death. Other independent risk factors for OS are shown in Table 2. Among the URD cohort, the probability of aGVHD grade B-D and C-D at 100 days was 59% (95%, CI 57–61%) and 32% (30-34%). In multivariate analysis, BM with MA (TBI and no TBI) or RIC conditioning (groups 2, 4 and 6) were significantly associated with lower odds ratio of grade B-D aGVHD (Table 1). Other independent risk factors included a diagnosis of CML. HCT from a 7/8 HLA-mismatched URD showed a trend for higher incidence of aGVHD (p=0.02). The probability of OS was 38% (95% CI: 35–40%) at 3 y and 33% (95% CI: 31–35%) at 5 y. In multivariate analysis, grade B-D aGVHD was associated with a higher mortality. Table 2 shows other independent risk factors for OS. Conclusion: Intensity of the conditioning regimen, TBI and the graft source has a combined effect on the risk of aGVHD. In both SD and URD cohorts, BM with MA, non-TBI regimens were associated with lower risk of aGVHD. In URD cohort, BM after a RIC also was associated with a reduced risk of aGVHD. Modulation of these risk factors is needed to reduce acute GVHD incidence and death after allogeneic transplantation. Disclosures: No relevant conflicts of interest to declare.

scholarly journals What Are the Risk Factors for Adjacent Vertebral Fracture After Vertebral Augmentation? A Meta-Analysis of Published Studies

2020 ◽  
pp. 219256822097822
Author(s):  
Tianyu Zhang ◽  
Yanhua Wang ◽  
Peixun Zhang ◽  
Feng Xue ◽  
Dianying Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vertebral Fracture ◽  
Cobb Angle ◽  
Meta Analysis ◽  
Cement Leakage ◽  
Thoracolumbar Junction ◽  
Vertebral Augmentation ◽  
T Score ◽  
Intravertebral Cleft ◽  
Adjacent Vertebral Fracture

Study Design: Meta-analysis. Objectives: To provide up-to-date evidence-based outcomes for the incidence and risk factors of adjacent vertebral fracture (AVF) after the vertebral augmentation. Methods: The MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were searched for studies assessing the risk factors of adjacent vertebral fracture after vertebral augmentation until June 2020. The AVF incidence and factors potentially affecting AVF were extracted and pooled. Results: A total of 16 studies, encompassing 2549 patients were included in the meta-analysis. The pooled incidence of AVF was 14% after vertebral augmentation. Female, lower T-score, thoracolumbar junction fracture, intravertebral cleft, more injected cement volume, intradiscal cement leakage significantly increased the risk of AVF. Age, body mass index, steroid medication, Cobb angle change, postoperative Cobb angle showed no significant association with AVF. Conclusions: Identifying the risk factors of AVF can facilitate prevention strategy to avoid the AVF. Female, T-score, thoracolumbar junction fracture, intravertebral cleft, more cement volume, and intradiscal cement leakage increased the risk of AVF.

scholarly journals Parental Risk Factors and Child Birth Data in a Matched Year and Sex Group Cleft Population: A Case-Control Study

2021 ◽  
Vol 18 (9) ◽  
pp. 4615
Author(s):  
Inês Francisco ◽  
Francisco Caramelo ◽  
Maria Helena Fernandes ◽  
Francisco Vale
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Body Mass ◽  
Odds Ratio ◽  
Maternal Body Mass Index ◽  
Related Factors ◽  
Mass Unit ◽  
Parental Risk Factors ◽  
Increase Odds Ratio ◽  
Birth Data

(1) Background: The etiology of orofacial cleft (OC) is not completely known but several genetic and environmental risk factors have been identified. Moreover, a knowledge gap still persists regarding neonatal characteristics. This study evaluated the effect of parental age and mothers’ body mass index on the risk of having an OC child, in a matched year and sex group (cleft/healthy control). Additionally, birth data were analyzed between groups. (2) Methods: 266 individuals born between 1995 to 2015 were evaluated: 133 OC individuals (85 males/48 females) and 133 control (85 males/48 females). A logistic model was used for the independent variables. ANOVA or Kruskal-Wallis tests were used for comparison between the OC phenotypes. (3) Results: Regarding statistically significant parental related factors, the probability of having a cleft child decreases for each maternal year increase (odds ratio = 0.903) and increases for each body mass index unit (kg/m2) increase (odds ratio = 1.14). On the child data birth, for each mass unit (kg) increase, the probability of having a cleft child decrease (odds ratio = 0.435). (4) Conclusions: In this study, only maternal body mass index and maternal age found statistical differences in the risk of having a cleft child. In the children’s initial data, the cleft group found a higher risk of having a lower birth weight but no relation was found regarding length and head circumference.

Early Onset Pneumonia

2004 ◽  
Vol 100 (2) ◽  
pp. 234-239 ◽  
Author(s):  
Régis Bronchard ◽  
Pierre Albaladejo ◽  
Gilles Brezac ◽  
Arnaud Geffroy ◽  
Pierre-François Seince ◽  
...  
Keyword(s):  
Risk Factors ◽  
Confidence Interval ◽  
Head Trauma ◽  
Early Onset ◽  
Odds Ratio ◽  
Nasal Carriage ◽  
Arterial Oxygen ◽  
Surgical Intensive Care Unit ◽  
Trauma Patients ◽  
Independent Risk Factors

Background Early onset pneumonia occurs frequently in head trauma patients, but the potential consequences and the risk factors of this event have been poorly studied. Methods This prospective observational study was undertaken in the surgical intensive care unit of a university teaching hospital in Clichy, France. Head trauma patients requiring tracheal intubation for neurologic reasons and ventilation for at least 2 days were studied to assess the risk factors and the consequences of early onset pneumonia. Results During a 2-yr period, 109 head trauma patients were studied. The authors found an incidence of early onset pneumonia of 41.3%. Staphylococcus aureus was the most common bacteria involved in early onset pneumonia. Patients with early onset pneumonia had a lower worst arterial oxygen tension:fraction of inspired oxygen ratio, more fever, more arterial hypotension, and more intracranial hypertension, factors known to worsen the neurologic prognosis of head trauma patients. Nasal carriage of S. aureus on admission (odds ratio, 5.1; 95% confidence interval, 1.9-14.0), aspiration before intubation (odds ratio, 5.5; 95% confidence interval, 1.9-16.4) and barbiturate use (odds ratio, 3.9; 95% confidence interval, 1.2-12.8) were found to be independent risk factors of early onset pneumonia. Conclusions The results suggest that early onset pneumonia leads to secondary injuries in head-injured patients. Nasal carriage of S. aureus, aspiration before intubation, and use of barbiturates are specific independent risk factors for early onset pneumonia and must be assessed to find and evaluate strategies to prevent early onset pneumonia.

scholarly journals Risk factors of contrast extravasation and subsequent hemorrhagic transformation after thrombectomy

2021 ◽  
Vol 49 (10) ◽  
pp. 030006052110490
Author(s):  
Keqin Liu ◽  
Lin Jiang ◽  
Yuqi Zhao ◽  
Wenqing Xia ◽  
Jie Ruan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Odds Ratio ◽  
Multivariate Analyses ◽  
Independent Predictor ◽  
Hemorrhagic Transformation ◽  
Stent Retriever ◽  
Contrast Extravasation ◽  
Endovascular Thrombectomy ◽  
Factors Associated ◽  
Radiological Data

Objective The risk factors associated with iodine contrast extravasation immediately after endovascular thrombectomy (EVT) and subsequent hemorrhagic transformation within 24 hours remain unclear. Methods Mixed images, iodine overlay maps, and virtual non-contrast images were reconstructed from 106 consecutive acute ischemic stroke patients who underwent dual energy computed tomography immediately and 24 hours after EVT. Multivariate analyses of clinical and radiological data were performed to explore independent predictors of iodine contrast extravasation and hemorrhagic transformation. Results Sixty-eight (64.2%) patients exhibited pure iodine contrast extravasation after EVT; 30.9% developed hemorrhagic transformation within 24 hours after EVT. The number of stent retriever passes was independently associated with both iodine contrast extravasation (odds ratio 1.608; 95% confidence interval (CI) 1.047–2.469) and subsequent hemorrhagic transformation (odds ratio 1.477; 95% CI 1.003–2.175). Patients with more than two stent retriever passes were more likely to exhibit iodine contrast extravasation (sensitivity = 68.2%, specificity = 81.5%), while those with more than three stent retriever passes more often exhibited hemorrhage after iodine contrast extravasation (sensitivity = 64.6%, specificity = 87.2%). Conclusions The number of stent retriever passes was an independent predictor for both iodine contrast extravasation and subsequent hemorrhagic transformation.

scholarly journals Environmental Risk Factors for Early-Onset Alzheimer’s Dementia and Frontotemporal Dementia: A Case-Control Study in Northern Italy

2020 ◽  
Vol 17 (21) ◽  
pp. 7941 ◽  
Author(s):  
Giorgia Adani ◽  
Tommaso Filippini ◽  
Caterina Garuti ◽  
Marcella Malavolti ◽  
Giulia Vinceti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Frontotemporal Dementia ◽  
Environmental Risk ◽  
Early Onset ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Environmental Risk Factors ◽  
Control Study

Background: Early-onset dementia (EOD) is defined as dementia with symptom onset before 65 years. The role of environmental risk factors in the etiology of EOD is still undefined. We aimed at assessing the role of environmental risk factors in EOD etiology, taking into account its different clinical types. Methods: Using a case-control study, we recruited all EOD cases referred to Modena hospitals from 2016 to 2019, while the referent population was drawn from cases’ caregivers. We investigated residential history, occupational and environmental exposures to chemicals and lifestyle behaviors through a self-administered questionnaire. We computed the odds ratios of EOD risk (overall and restricting to the Alzheimer’s dementia (AD) or frontotemporal dementia (FTD) diagnoses) and the corresponding 95% confidence intervals using an unconditional logistic regression model. Results: Fifty-eight EOD patients (19 FTD and 32 AD) and 54 controls agreed to participate. Most of the investigated exposures, such as occupational exposure to aluminum, pesticides, dyes, paints or thinners, were associated with an increased odds ratio (OR) for FTD but not for AD. Long-term use of selenium-containing dietary supplements was associated with increased OR for EOD and, particularly, for FTD. For both EOD forms, smoking and playing football showed an increased odds ratio, while cycling was associated with increased risk only in FTD. Overall sports practice appeared to be a protective factor for both types. Conclusions: Our results suggest a role of environmental and behavioral risk factors such as some chemical exposures and professional sports in EOD etiology, in particular with reference to FTD. Overall sports practice may be associated with a reduced EOD risk.

Nghiên cứu một số yếu tố nguy cơ của nhiễm khuẩn sơ sinh sớm tại Bệnh viện Trường Đại học Y Dược Huế

2021 ◽  
Author(s):  
Thanh Binh Nguyen Thi
Keyword(s):  
Risk Factors ◽  
Early Onset ◽  
Abdominal Distension ◽  
Neonatal Infection ◽  
Total Sample ◽  
Peripheral Circulation ◽  
Infected Group ◽  
Related Factors ◽  
Perinatal Risk Factors ◽  
Perinatal Risk

TÓM TẮT Đặt vấn đề: Nhiễm khuẩn sơ sinh sớm là một trong những nguyên nhân gây tử vong cao ở giai đoạn sơ sinh nhưng việc chẩn đoán sớm còn gặp nhiều khó khăn. Vì thế, chúng tôi tiến hành nghiên cứu này nhằm mục đích tìm hiểu các yếu tố nguy cơ giúp thiết lập chẩn đoán nhiễm khuẩn sơ sinh sớm. Đối tượng, phương pháp: Nghiên cứu hồi cứu. Lấy mẫu toàn bộ gồm 295 trẻ sơ sinh được chẩn đoán nghi ngờ nhiễm khuẩn sơ sinh sớm trong 72 giờ đầu sau sinh. Sau đó, chia thành hai nhóm: nhóm nhiễm khuẩn (các trường hợp nhiễm khuẩn hay có khả năng nhiễm khuẩn) và nhóm không nhiễm khuẩn để so sánh. Địa điểm nghiên cứu: phòng Nhi sơ sinh, Bệnh viện Trường Đại học Y Dược Huế từ tháng 5/2019 đến tháng 5/2020. Kết quả: Tỷ lệ của nhóm nhiễm khuẩn là 57,3%. Các yếu tố liên quan giúp chẩn đoán nhiễm khuẩn sơ sinh sớm bao gồm: ối vỡ non (OR = 4,7), thời gian ối vỡ trên 18 giờ (OR = 2,5), da tái, nổi vân tím (OR = 14,9), trẻ có chỉ định thở máy (OR = 8,7), suy hô hấp bắt đầu sau 4 giờ tuổi (OR = 6,8), kém linh hoạt (OR = 6,6), bụng chướng (OR = 4,2), thở nhanh (OR = 2,7), nôn (OR = 2,3), số lượng bạch cầu trong máu ngoại vi > 25 x 109/L (OR = 5,7), tỷ lệ bạch cầu đa nhân trung tính > 65% (OR = 2,0) và nồng độ CRP huyết thanh > 10 mg/L (OR = 8,0). Kết luận: Việc phối hợp các yếu tố nguy cơ trong thai kỳ, triệu chứng lâm sàng và cận lâm sàng, giúp xác định chẩn đoán nhiễm khuẩn sơ sinh sớm, nhằm hạn chế tối đa việc sử dụng kháng sinh không cần thiết ở trẻ sơ sinh. Từ khóa: Sơ sinh, nhiễm khuẩn sơ sinh sớm, yếu tố nguy cơ trước sinh ABSTRACT RELATED FACTORS OF EARLY-ONSET NEONATAL INFECTION AT HUE UNIVERSITY OF MEDICINE AND PHARMARCY HOSPITAL Background: Early - onset neonatal infection is an important cause of morbidity and mortality in neonates and it’s diagnosis remains challenging. Therefore, this study aimed to describle the related factors that can help establish the diagnosis of early - onset neonatal infection. Methods: A retrospective study. A total sample of 295 neonates at Hue University of Medicine and Pharmacy Hospital, Hue, Viet Nam from 5/2019 - 5/2020, who were suspected to suffer from infection within the first 72 hours of life. Then, they were classified as infected group (confirmed or possible infected) and non - infected group to compare. Results: The prevalence of infected group is 57,3%. Some related factors of early - onset neonatal infection are: prelabour rupture of membranes (OR=4,7), rupture of membranes for more than 18 hours (OR = 2,5), pale or mottled skin (OR = 14,9), need for mechanical ventilation (OR = 8,7), respiratory distress starting more than 4 hours after birth (OR = 6,8), responsiveness (OR = 6,6), abdominal distension (OR = 4,2), tachypnoea (OR = 2,7),vomiting (OR = 2,3), white blood cell in peripheral circulation > 25 x 109/L (OR = 5,7), neutrophil ratio in peripheral circulation > 65% (OR = 2,0) and CRP concentrations > 10 mg/L (OR = 8,0). Conclusions: Combination of perinatal risk factors, clinical and subclinical characteristcs are highly suggestive for early - onset neonatal infection will help to reduce the numbers of babies given antibiotics unnecessarily. Key words: Neonate, early - onset infection, perinatal risk factors

Sign in / Sign up

Export Citation Format

Share Document