scholarly journals Does Intramedullary Nailing for Distal Fibular Fractures Restore Anatomic Parameters and Syndesmotic Relationship?

2020 ◽  
Vol 5 (2) ◽  
pp. 2473011420S0000
Author(s):  
Natalio R. Cuchacovich Mikenberg ◽  
Francisco J. Bravo Gallardo ◽  
Esteban Giannini ◽  
Claudia Astudillo ◽  
Manuel J. Pellegrini ◽  
...  
Keyword(s):  
Statistical Power ◽  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Wilcoxon Test ◽  
Medium Size ◽  
Control Group ◽  
Cross Sectional ◽  
Rotation Length ◽  
Paired Control

Category: Trauma; Ankle Introduction/Purpose: Fibular nailing (FN) is a method of fixation that has proven to be useful for the treatment of distal fibular fractures (DF). FN minimizes soft tissue complications, provides similar stability compared to plating with less hardware related symptoms. Nevertheless, FN has been associated with syndesmotic malreduction and incapacity of restoring length and rotation of the fibula. We aimed to evaluate the fibular and syndesmotic reduction after fixation with FN compared to the uninjured ankle. Methods: Prospective cohort, cross-sectional study with a paired control group. Patients with DF fractures treated with FN between January 2017 and July 2019 were included. Immediate postoperative bilateral Ankle CT was obtained in all cases. Two independent radiologists performed all the measurements on both ankles (fibular rotation, length, translation, and syndesmotic diastasis. Statistical analysis was made using the Wilcoxon Test and Intraclass correlation coefficient (ICC). Considering a medium size sample effect, 95% confidence with .05 alpha error, a total sample of 26 subjects were needed to achieve a .80 of statistical power (G-Power 3.1). All analyses were performed using SPSS V20. Results: Twenty-six patients were included (14 Women). The mean age was 47 years (18-91). No statistically significant differences were identified considering fibular rotation (p:0,694), fibular length (p:0,585) and syndesmotic diastasis (p:0,078) between the injured and uninjured ankle. Fibular translation has statistical differences (p:0,043). The ICC shows an excellent concordance between radiologists except for Fibular translation (ICC 0,47) Conclusion: In this cohort, fixation of DF fractures with FN allows restoration of anatomical parameters of the ankle in terms of fibular rotation, length, and syndesmotic diastasis. However, Fibular translation had significant differences compared with the uninjured ankle.

scholarly journals Development and evaluation of a diet quality screener to assess adherence to the Dutch food-based dietary guidelines

2021 ◽  
pp. 1-28
Author(s):  
Mariëlle G de Rijk ◽  
Anne I Slotegraaf ◽  
Elske M Brouwer-Brolsma ◽  
Corine WM Perenboom ◽  
Edith JM Feskens ◽  
...  
Keyword(s):  
Diet Quality ◽  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Dietary Guidelines ◽  
Full Length ◽  
Cross Sectional ◽  
Maximum Score ◽  
The Mean ◽  
Excellent Reproducibility

Abstract The Eetscore FFQ was developed to score the Dutch Healthy Diet index 2015 (DHD2015-index) representing the Dutch food-based dietary guidelines of 2015. This paper describes the development of the Eetscore FFQ, a short screener assessing diet quality, examines associations between diet quality and participants’ characteristics, and evaluates the relative validity and reproducibility of the Eetscore FFQ in a cross-sectional study with Dutch adults. The study sample consisted of 751 participants, aged 19-91 y, recruited from the EetMeetWeet research panel. The mean DHD2015-index score based on the Eetscore FFQ of the total sample was 111 (SD 17.5) out of a maximum score of 160 points and was significantly higher in women than in men, positively associated with age and education level, and inversely associated with BMI. The Kendall’s tau-b coefficient of the DHD2015- index between the Eetscore FFQ and the full-length FFQ (on average 1.7-month interval, n=565) was 0.51 (95% CI 0.47, 0.55), indicating an acceptable ranking ability. The intraclass correlation coefficient (ICC) between DHD2015-index scores derived from two repeated Eetscore FFQs (on average 3.8-month interval, n=343) was 0.91 (95% CI: 0.89, 0.93) suggesting a very good reproducibility. In conclusion, the Eetscore FFQ was considered acceptable in ranking participants according to their diet quality compared with the full-length FFQ and showed good to excellent reproducibility.

The Norsjö-Cooperstown healthy heart project: A case study combining data from different studies without the use of meta-analysis

2001 ◽  
Vol 29 (56_suppl) ◽  
pp. 40-45 ◽  
Author(s):  
P.L. Jenkins ◽  
L. Weinehall ◽  
T.A. Erb ◽  
C. Lewis ◽  
A.N. Nafziger ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Risk Score ◽  
Significant Interaction ◽  
Statistical Power ◽  
Cross Sectional Study ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Combining Data

Objectives: This paper aims to develop and describe a method for combining, comparing, and maximizing the statistical power of two longitudinal studies of risk factors for cardiovascular disease that did not have identical data collection methodologies. Methods: Subjects from a 1986 cross-sectional study (n= 180) were pair-matched with subjects of corresponding gender and age (+ 5 years) from a 1990 cross-sectional study. The methodology is described and results are calculated for various measures of cardiovascular risk or risk factors (e.g. cholesterol, Finnish Risk Score). Results: Box's test of equality and symmetry of covariance matrices gave chi-square values of 223.8 and 710.0 for two cardiovascular risk factors (cholesterol and cardiac risk score, respectively); these values were highly significant (p=0.0001). For the North Karelia Risk Score, repeated measures ANOVA revealed a borderline significant interaction for treatment by time (p=0.054) and a significant interaction for treatment by time by country (p=0.035). These probabilities compared favorably with a randomized blocks model. Conclusions: Creation of a synthetic longitudinal control group resulted in a statistically valid ANOVA model that increased the statistical power of the study.

scholarly journals Reliability of SNIP test and optimal number of maneuvers in 6-11 years healthy children

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0252150
Author(s):  
Ana Aline Marcelino ◽  
Guilherme Fregonezi ◽  
Layana Marques ◽  
Ana Lista-Paz ◽  
Rodrigo Torres-Castro ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Optimal Number ◽  
Minimal Detectable Change ◽  
Healthy Children ◽  
Age Group ◽  
Older Children ◽  
Cross Sectional ◽  
Pediatric Populations

Background and purpose Sniff nasal inspiratory pressure (SNIP) is a voluntary inspiratory maneuver measured through a plug occluding one nostril. The investigation of the number of maneuvers necessary to reach the highest peak of SNIP in pediatric populations has been inconsistent. Thus, this study aimed to assess the reliability of SNIP in healthy children aged 6 to 11 years according to sex and age group, and to determine the optimal number of SNIP maneuvers for this age group. Methods This cross-sectional study included healthy children with normal pulmonary function. We performed 12 to 20 SNIP maneuvers, with a 30 s rest between each maneuver. The reliability was tested using the intraclass correlation coefficient (ICC), standard error of measurement (SEM), minimal detectable change (MDC), and Bland-Altman analysis for agreement. Results A total of 121 healthy children (62 girls [51%]) were included in this study. The ICC and corresponding confidence interval (CI) between the highest measure and the first reproducible maneuver were 0.752 (0.656–0.824), SEM = 10.37 cmH2O, and MDC = 28.74 cmH2O. For children aged 6 to 7 years, the ICC was 0.669 (0.427–0.822), SEM = 10.76 cmH2O and MDC = 29.82 cmH2O; for children aged 8 to 11 years, the ICC was 0.774 (0.662–0.852), SEM = 9.74 cmH2O, and MDC = 26.05 cmH2O. For girls, the ICC was 0.817 (0.706–0.889), SEM = 9.40 cmH2O and MDC = 26.05 cmH2O; for boys, the ICC was 0.671 (0.487–0.798), SEM = 11.51 cmH2O, and MDC = 31.90 cmH2O. Approximately 80% of the total sample reached the highest SNIP before the 10th maneuver. Conclusions SNIP demonstrated moderate reliability between the maneuvers in children aged 6 to 11 years; older children and girls reached the SNIP peak faster. Finally, results indicated that 12 maneuvers were sufficient for healthy children aged 6 to 11 years to achieve the highest SNIP peak.

scholarly journals In-Out-Test: A New Paradigm for Sorting the Wheat from the Chaff in Prodromal Alzheimer’s Disease

2019 ◽  
Vol 67 (1) ◽  
pp. 265-277
Author(s):  
Eduardo Torrealba ◽  
Pilar Garcia-Morales ◽  
Juan Carlos Cejudo ◽  
Mario Diaz ◽  
Francisco Rodriguez-Esparragon ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
New Paradigm ◽  
Progressive Dementia ◽  
Cross Sectional ◽  
Prodromal Alzheimer’S Disease ◽  
Selective Reminding Test

Background: Assessment of hippocampal amnesia is helpful to distinguish between normal cognition and mild cognitive impairment (MCI), but not for identifying converters to dementia. Here biomarkers are useful but novel neuropsychological approaches are needed in their absence. The In-out-test assesses episodic memory using a new paradigm hypothesized to avoid reliance on executive function, which may compensate for damaged memory networks. Objective: To assess the validity of the In-out-test in identifying prodromal Alzheimer’s disease (PAD) in a clinical setting, by comparing this to the Free and Cued Selective Reminding Test (FCSRT) and cerebrospinal fluid biomarkers. Methods: A cross-sectional study of 32 cognitively healthy, 32 MCI, and 30 progressive dementia subjects. All participants were given both the In-out-test and the FCSRT; 40 of them also received a lumbar puncture. Results: Internal consistency was demonstrated using Cronbach Alpha (r = 0.81) and Inter-rater reliability with Kappa (k = 0.94). Intraclass correlation (ICC) for test-retest reliability: r = 0.57 (p = 0.57). ICC between the In-out-test and FCSRT r = 0.87 (p = 0.001). ICC between the In-out-test and Aβ42 and P-tau/Aβ42 for controls: 0.73 and 0.75, respectively; P-tau for MCI: 0.77 and total sample: 0.70; Aβ42 for dementia: 0.71. All ICC measures between FCSRT and biomarkers were ≤0.264. AD diagnosis: In-out-test k = 0.71; FCSRT k = 0.49. PAD diagnosis (N = 35): In-out-test k = 0.69; FCSRT k = 0.44. Conclusions: The In-out-test detected prodromal AD with a higher degree of accuracy than a conventional hippocampal-based memory test. These results suggest that this new paradigm could be of value in clinical settings, predicting which patients with MCI will go on to develop AD.

scholarly journals Development and administration of a postural and ergonomic assessment tool: a pilot study

2015 ◽  
Vol 28 (3) ◽  
pp. 509-523
Author(s):  
Renata Chlalup Silveira ◽  
Marcelo La Torre ◽  
Isabel Guglielmone
Keyword(s):  
Content Validity ◽  
Assessment Tool ◽  
Intraclass Correlation ◽  
Cross Sectional Study ◽  
Wilcoxon Test ◽  
Cross Sectional ◽  
Sitting Posture ◽  
Prevention And Health Promotion ◽  
Quantitative Descriptive ◽  
High Degree

AbstractIntroduction Prevention of occupational diseases depends on the identification of risk factors, which can be complemented by the functional assessment of workers.Objective The aim of this study was to develop a postural and ergonomic assessment tool for the analysis of subjects’ sitting posture at the computer workstation.Materials and methods This is a quantitative, descriptive, observational, cross-sectional study. Eighty-two employees in the administrative sector of FIERGS were invited to participate in the study. The mean age was 32.8 ± 7.7 years. The IAPE (Instrumento de Avaliação Postural Ergonômica [Postural and Ergonomic Assessment Tool]) development and administration process was performed in four stages: 1) observation of the most commonly adopted postures by employees in the workplace; 2) development of the first version of the IAPE; 3) content validation by two ergonomics experts and content validity index (CVI) calculation; 4) inter-evaluator reproducibility assessment. Reproducibility was assessed by Wilcoxon test and intraclass correlation coefficient (ICC) (p < 0.05).Results The results obtained from the calculation of the CVI showed that the IAPE possesses a high degree of content validity (CVI = 1). Inter-evaluator reproducibility assessment showed no differences between evaluators (p < 0.05) and ICC values above 0.80 (p < 0.05). This shows an adequate inter-evaluator reproducibility of the tool.Conclusion Based on the results of the IAPE development process, it can be concluded that the tool has content validity and adequate inter-evaluator reproducibility. This tool can aid in the development of occupational disease prevention and health promotion strategies.

scholarly journals Comparison of Fetal Cerebellum and Cisterna Magna Length by 2D and 3D Ultrasonography between 18 and 24 Weeks of Pregnancy

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Fernanda Silveira Bello de Barros ◽  
Luiz Cláudio de Silva Bussamra ◽  
Edward Araujo Júnior ◽  
Leonardo da Silva Valladão de Freitas ◽  
Luciano Marcondes Machado Nardozza ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Gestational Age ◽  
Intraclass Correlation ◽  
Three Dimensional ◽  
Cross Sectional Study ◽  
Wilcoxon Test ◽  
Cross Sectional ◽  
Cisterna Magna ◽  
Length Measurements ◽  
The Difference

To compare the fetal cerebellum and cisterna magna length measurements by means of two- (2DUS) and three-dimensional (3DUS) ultrasonography using the three-dimensional extended imaging (3D XI), a cross-sectional study with 69 healthy pregnant women between 18 and 24 weeks was performed. For the measurements by 2DUS, the axial planes were used and for the 3DUS a sequence of adjacent axial slices (multislice view). To evaluate the difference between the two techniques, we used the Wilcoxon test. To evaluate the correlation between the cerebellum and cisterna magna length measurements and the gestational age, we used the Spearman correlation coefficient (r). For the calculation of reproducibility, we used the intraclass correlation coefficient (ICC). The mean of the transverse and anterior-posterior diameter of cerebellum and cisterna magna by 3DUS was 9.23 and 6.62 mm, respectively. It was observed that the average of the measurements obtained by 3DUS was significantly higher, 0.76 and 1.02 mm for the length of the cerebellum and cisterna magna, respectively (P<0.001). There was a high correlation between the length measurement of the cerebellum 3D (r=0.940, P<0.001), but low correlation of cisterna magna 3D (r=0.462, P=0.080) with the gestational age. There was good intra- and interobserver reproducibility for the cerebellum and cisterna magna 3D with ICC=0.792 , 0.668, 0.691, and 0.287, respectively. The measurements of the fetal cerebellum and cisterna magna length by 3DUS using the software 3D XI were significantly higher than those obtained by 2DUS.

scholarly journals Reliability of SNIP test in healthy children from 6 to 11 years.

2020 ◽  
Author(s):  
Ana Aline Marcelino ◽  
Guilherme Fregonezi ◽  
Layana Marques ◽  
Ana Lista-Paz ◽  
Rodrigo Torres-Castro ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Minimal Detectable Change ◽  
Healthy Children ◽  
Older Children ◽  
Cross Sectional ◽  
Residual Capacity ◽  
Pediatric Populations ◽  
Standard Error Of Measurement

Abstract Background Sniff nasal inspiratory pressure (SNIP) is a voluntary inspiratory maneuver measured through a plug occluding one nostril. The investigation of the number of maneuvers necessary to reach the highest peak of SNIP in pediatric populations has been inconsistent. Thus, our goal was to assess the reliability SNIP in healthy children aged 6 to 11 years and compare with regard to sex and age group, as well as to determine the adequate number of maneuvers. Methods This cross-sectional study included healthy children with normal pulmonary function. Were performed 12 to 20 maneuvers SNIP near functional residual capacity, with a 30 s rest between each. Reliability was tested using intraclass correlation coefficient (ICC), standard error of measurement (SEM), minimal detectable change (MDC), and Bland-Altman analysis for agreement. Results A total of 121 children (62 girls [51%]) were included. The ICC and corresponding confidence interval (CI) between the highest measure and the first reproducible maneuver was 0.752 (0.656–0.824), SEM of 10.37 cmH2O and MDC of 28.74 cmH2O. For children aged 6–7 and 8–11 years, the ICC (CI) was 0.669 (0.427–0.822), SEM = 10.76 cmH2O and MDC = 29.82 cmH2O, and 0.774 (0.662–0.852), with SEM = 9.74 cmH2O and MDC = 26.05 cmH2O, respectively. For girls, the ICC (CI) was 0.817 (0.706–0.889), SEM = 9.40 cmH2O and MDC = 26.05 cmH2O; for boys, 0.671 (0.487–0.798), SEM = 11.51 cmH2O and MDC = 31.90 cmH2O. Approximately 80% of the total sample reached the highest SNIP before the 10th maneuver. Conclusions SNIP demonstrated moderate reliability between the maneuvers in children aged 6 to 11 years. Otherwise, older children and girls reached the SNIP peak faster. Finally, results suggested that 12 maneuvers were sufficient for healthy children aged 6 to 11 years to achieve the highest SNIP peak.

scholarly journals Study of corneal biomechanical properties in patients with childhood glaucoma

2020 ◽  
Vol 13 (12) ◽  
pp. 1922-1927
Author(s):  
Sara Garcia Caride ◽  
Federico Sáenz Francés ◽  
Julián García Feijoo
Keyword(s):  
Pearson Correlation ◽  
Corneal Thickness ◽  
Intraclass Correlation ◽  
Clinical History ◽  
Biomechanical Properties ◽  
Cross Sectional Study ◽  
Control Group ◽  
Ophthalmological Examination ◽  
Cross Sectional ◽  
Corneal Biomechanical Properties

AIM: To study of corneal biomechanical properties and intraocular pressure (IOP) measured with Corvis Scheimpflug Technology (ST) in patients with childhood glaucoma (CG). METHODS: Cross-sectional study in which 89 eyes were included 56 of them with CG. Only one eye per patient was included. The following variables were obtained from the clinical history and the ophthalmological examination: age, sex, IOP, number of surgeries, and the cup/disc ratio (CDR). The following parameters were recorded using Corvis ST: corrected by biomechanics IOP (bIOP), not corrected IOP (nctIOP), central corneal thickness (CCT), maximum concavity [radius, peak distance (PD) and deformation amplitude], applanation 1 and 2 (length and velocity). The mean age was 23±14.55 and 33±19.5 years old for the control group and CG group, respectively. Totally 36 were males and 53 were females. In the CG group, 7 patients were controlled only with medical treatment. Sixteen had at least one previous goniotomy, 19 had at least one trabeculectomy, and 11 had an Ahmed implant. RESULTS: A significant and positive intraclass correlation coefficient was found between Goldman IOP and the IOP measured by Corvis in both groups. No differences were found between the IOP measured with Corvis and Goldman using a student t-test. Regarding biomechanical parameters, there were differences in the applanation length 2 (A-L2), in the applanation velocity 2 (A-V2) and in the PD. By sex, only the applanation length 1 (A-L1) was found to be different in control group. A positive and significant Pearson correlation was found between CDR and the A-L1. CONCLUSION: Corneal biomechanical properties have shown differences between CG and healthy subjects and also between men and women.

DYSLIPIDEMIA IN THYROID DISORDERS

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Kashish Narula ◽  
Narendra Kumar Dara ◽  
Shyam Lal Meena
Keyword(s):  
Lipid Metabolism ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Control Group ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
Carbohydrate And Lipid Metabolism ◽  
History Of ◽  
Thyroid Profile ◽  
Basal Energy Expenditure

Background: Thyroid hormones influence nearly all major metabolic pathways. Their most obvious and well-known action is the increase in basal energy expenditure obtained by acting on protein, carbohydrate and lipid metabolism. The lipid metabolism is more influenced by the thyroid hormone. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results: The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: Dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Thyroid profile, Total cholesterol, Triglycerides and LDL

Pengaruh bising lalu lintas terhadap penurunan fungsi pendengaran pada juru parkir di kota Denpasar

2013 ◽  
Vol 40 (2) ◽  
Author(s):  
Ni Ketut Susilawati ◽  
Wayan Sudana ◽  
Eka Putra Setiawan
Keyword(s):  
Hearing Impairment ◽  
Noise Exposure ◽  
Traffic Noise ◽  
Hearing Threshold ◽  
Noise Pollution ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Hearing Function

Background: Noise pollution or noise is an unwanted sound which is disturbing to human beings.However small or soft the sound, if it is undesirable it is considered as noise. Noise induced hearingloss is a sensorineural hearing loss that is commonly encountered second to presbycusis. Purpose: Toknow the effect of traffic noise exposure on hearing impairment to the employees of the Parking DistrictCompany of the Denpasar city and to improve diagnostic detection on hearing impairment caused bynoise. Method: A cross sectional study was conducted at the Parking District Company office. Thepopulations of this study were the employees of the Parking District Company. Samples of this study were the employees who were exposed to traffic noise and control samples were an employee who was unexposed. Samples were selected by simple random sampling. Results: From 40 parking attendants,27 persons (67.5%) aged above 35 years old. The parking attendants who had been working for ten to fifteen years were 36 persons (90%) and no history using ear protection when working. Seven persons(17.5%) had referred DPOAE upon examination with increase hearing threshold on audiogram result.In this study the parking attendants who had hearing deficit induced by noise were 7 persons (17.5%)and only one person (2.5%) in control group. There was a statistically significant effect of traffic noiseto hearing function deficit (p<0.05). Conclusion: Traffic noise has effect in hearing function deficit onthe parking attendants.ORLI Vol. 40 No. 2 Tahun 2010Key words: NIHL, parking attendant, audiometry, DPOAE.

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