scholarly journals A STATISTICAL STUDY OF MORTALITY FROM LEUKEMIA

Blood ◽  
1947 ◽  
Vol 2 (1) ◽  
pp. 1-14 ◽  
Author(s):  
MILTON S. SACKS ◽  
ISADORE SEEMAN
Keyword(s):  
United States ◽  
Acute Leukemia ◽  
Death Rate ◽  
Myeloid Leukemia ◽  
Age Distribution ◽  
The United States ◽  
Age Group ◽  
Death Rates ◽  
Rate Of Increase ◽  
The Difference

Abstract The recorded death rate from leukemia in the United States has risen continuously since 1900, with an accelerated rate of increase since 1930. The rise from a rate of 1.9 per 100,000 population in 1920 to 3.7 in 1940 represents an increase of 94.7 per cent in this twenty-year period. This increase cannot be accounted for by changes in the age distribution of the population, for the age specific death rates have increased in each age group. The factor of increasing recognition of the disease resulting from improved diagnostic technics and greater use of hospitals with their laboratory facilities must be given adequate consideration in an effort to determine the causes for the rising death rate. White persons are affected at a rate more than twice as great as nonwhites. Some of the difference must be attributed to variations in the availability of diagnostic services. Males experience a rate approximately one-third greater than females. Leukemia affects persons in the older ages, particularly over 55 years, with the greatest frequency, and the population under 5 years of age experiences a mortality rate higher than any other age under 45 years. In the intermediate ages the death rate falls to the lowest point. In 1940 the death rate from leukemia for all ages was 3.7 per 100,000 population. The highest rate, 15.7 per 100,000 occurred in the age group 75-84 years. Under 1 year the rate was 4.9 per 100,000. The lowest rate, 1.5 per 100,000, occurred in the ages from 15 to 2.4 years. Figures for the city of Baltimore for the five-year period 1939-1943 indicate an almost equal incidence of lymphoid and myeloid leukemia. Nearly two-thirds of the deaths studied in Baltimore were reported as acute leukemia. Acute myeloid leukemia appears to be more common than acute lymphoid. After age 45 chronic leukemia is more frequently observed; younger persons experience acute leukemia most commonly. Undoubtedly many deaths result from leukemia in which this disease was neither diagnosed nor recorded on a death certificate. Clinical evidence indicates that the causes in which this failure would occur most commonly are cancer, anemia, and diseases of the spleen. Statistical evidence reveals that these conditions are certified jointly with leukemia in a significant number and proportion of cases. Comparison of the experience of several countries indicates that the general trends of mortality from leukemia in the United States are common to the other communities. The death rates per 100,000 population in 1931 adjusted for differences in age and sex composition of the population were: United States, 3.5; England and Wales, 3.0; Paris 2.5; and Canada 2.3. Each year since 1940 more than 5,000 persons in the United States have died from leukemia.

Calculating Age-Standardized Death Rates Among People With HIV Comparable Across Jurisdictions and Over Time

2021 ◽  
Vol 111 (1) ◽  
pp. 121-126
Author(s):  
Qiang Xia ◽  
Ying Sun ◽  
Chitra Ramaswamy ◽  
Lucia V. Torian ◽  
Wenhui Li
Keyword(s):  
United States ◽  
New York ◽  
New York City ◽  
York City ◽  
Death Rate ◽  
Age Distribution ◽  
The United States ◽  
Local Health ◽  
Death Rates ◽  
Over Time

The Centers for Disease Control and Prevention (CDC) and local health jurisdictions have been using HIV surveillance data to monitor mortality among people with HIV in the United States with age-standardized death rates, but the principles of age standardization have not been consistently followed, making age standardization lose its purpose—comparison over time, across jurisdictions, or by other characteristics. We review the current practices of age standardization in calculating death rates among people with HIV in the United States, discuss the principles of age standardization including those specific to the HIV population whose age distribution differs markedly from that of the US 2000 standard population, make recommendations, and report age-standardized death rates among people with HIV in New York City. When we restricted the analysis population to adults aged between 18 and 84 years in New York City, the age-standardized death rate among people with HIV decreased from 20.8 per 1000 (95% confidence interval [CI] = 19.2, 22.3) in 2013 to 17.1 per 1000 (95% CI = 15.8, 18.3) in 2017, and the age-standardized death rate among people without HIV decreased from 5.8 per 1000 in 2013 to 5.5 per 1000 in 2017.

Impact of Safety Packaging on Accidental Poisoning

PEDIATRICS ◽  
1979 ◽  
Vol 63 (5) ◽  
pp. 816-817 ◽  
Author(s):  
Robert G. Scherz
Keyword(s):  
United States ◽  
Death Rate ◽  
The United States ◽  
Accidental Poisoning ◽  
Age Group ◽  
Accidental Death ◽  
Death Rates ◽  
The Past ◽  
Group 15 ◽  
The One

During the past 20 years (1957-1977), the accidental death rates in the United States from poisoning by solids and liquids have changed greatly. The death rate per 100,000 population rose steadily from 0.8 in 1957 to 2.2 in 1975 and then decreased to 1.9 in 1976 and an estimated 1.8 in 1977. The increase in death rates since 1957 was due mostly to changes in the age group 15 to 44 years. There were smaller increases in the groups 5 to 14 years and the 45 years and older. The only age group that has shown a consistent decline has been the one younger than age 5 years.

The altered seasons of death in America

1972 ◽  
Vol 4 (2) ◽  
pp. 145-151 ◽  
Author(s):  
W. R. Lyster
Keyword(s):  
United States ◽  
The United States ◽  
Seasonal Distribution ◽  
Fertility Rates ◽  
Death Rates ◽  
The Difference ◽  
The 1960S

The seasonal distribution of deaths in the United States has progressively altered since 1940. The proportion of deaths in the first half of the year has declined. During the 1940s there were 7·44% more deaths in the first half than in the second half of the year, but during the 1960s the difference was only 4·85%.The continuous shift in the seasonal distribution of the crude death rates from all causes is in association with a similar movement in the monthly fertility rates of the United States.

The Demand for Pharmaceuticals in Major International Markets

2018 ◽  
Author(s):  
Stuart O. Schweitzer ◽  
Z. John Lu
Keyword(s):  
United States ◽  
Central Government ◽  
Age Distribution ◽  
Pharmaceutical Expenditure ◽  
National Income ◽  
The United States ◽  
International Markets ◽  
The United Kingdom ◽  
The Difference

This chapter provides a comparative analysis of pharmaceutical expenditure levels across major global markets. It identifies several factors for the difference across countries, including national income, spending on overall healthcare, price for substitutable healthcare products and services, age distribution, patient and physician tastes and preferences, and even culture. The discussion focuses on seven of the largest national markets outside the United States: Japan, China, France, Germany, the United Kingdom, Canada, and Brazil. While there are notable differences between these markets, one especially important commonality distinguishes them from the United States: in every single market, the central government plays a pivotal role in the determination of drug prices by using its monopsonist power in negotiations with and regulations of drug manufacturers.

scholarly journals Changing Spatiotemporal Trends in County‐Level Heart Failure Death Rates in the United States, 1999 to 2018

2021 ◽  
Vol 10 (4) ◽  
Author(s):  
Adam S. Vaughan ◽  
Mary G. George ◽  
Sandra L. Jackson ◽  
Linda Schieb ◽  
Michele Casper
Keyword(s):  
United States ◽  
Heart Failure ◽  
Ethnic Group ◽  
The United States ◽  
Local Context ◽  
County Level ◽  
Age Group ◽  
Death Rates ◽  
Spatiotemporal Trends ◽  
Racial Ethnic

Background Amid recently rising heart failure (HF) death rates in the United States, we describe county‐level trends in HF mortality from 1999 to 2018 by racial/ethnic group and sex for ages 35 to 64 years and 65 years and older. Methods and Results Applying a hierarchical Bayesian model to National Vital Statistics data representing all US deaths, ages 35 years and older, we estimated annual age‐standardized county‐level HF death rates and percent change by age group, racial/ethnic group, and sex from 1999 through 2018. During 1999 to 2011, ~30% of counties experienced increasing HF death rates among adults ages 35 to 64 years. However, during 2011 to 2018, 86.9% (95% CI, 85.2–88.2) of counties experienced increasing mortality. Likewise, for ages 65 years and older, during 1999 to 2005 and 2005 to 2011, 27.8% (95% CI, 25.8–29.8) and 12.6% (95% CI, 11.2–13.9) of counties, respectively, experienced increasing mortality. However, during 2011 to 2018, most counties (67.4% [95% CI, 65.4–69.5]) experienced increasing mortality. These temporal patterns by age group held across racial/ethnic group and sex. Conclusions These results provide local context to previously documented recent national increases in HF death rates. Although county‐level declines were most common before 2011, some counties and demographic groups experienced increasing HF death rates during this period of national declines. However, recent county‐level increases were pervasive, occurring across counties, racial/ethnic group, and sex, particularly among ages 35 to 64 years. These spatiotemporal patterns highlight the need to identify and address underlying clinical risk factors and social determinants of health contributing to these increasing trends.

Comparing the COVID-19 Responses in Cuba and the United States

2021 ◽  
Vol 111 (12) ◽  
pp. 2186-2193
Author(s):  
Mary Anne Powell ◽  
Paul C. Erwin ◽  
Pedro Mas Bermejo
Keyword(s):  
United States ◽  
Death Rate ◽  
Health Inequities ◽  
The United States ◽  
Death Rates ◽  
Excess Death ◽  
Future Studies ◽  
Effective Strategies ◽  
The Us ◽  
Case Rate

The purpose of this analytic essay is to contrast the COVID-19 responses in Cuba and the United States, and to understand the differences in outcomes between the 2 nations. With fundamental differences in health systems structure and organization, as well as in political philosophy and culture, it is not surprising that there are major differences in outcomes. The more coordinated, comprehensive response to COVID-19 in Cuba has resulted in significantly better outcomes compared with the United States. Through July 15, 2021, the US cumulative case rate is more than 4 times higher than Cuba’s, while the death rate and excess death rate are both approximately 12 times higher in the United States. In addition to the large differences in cumulative case and death rates between United States and Cuba, the COVID-19 pandemic has unmasked serious underlying health inequities in the United States. The vaccine rollout presents its own set of challenges for both countries, and future studies can examine the comparative successes to identify effective strategies for distribution and administration. (Am J Public Health. 2021;111(12):2186–2193. https://doi.org/10.2105/AJPH.2021.306526 )

Confirmation of Tabachnick and Klugman's Hypothesis That the Death Instinct is Constant

1992 ◽  
Vol 74 (3_suppl) ◽  
pp. 1065-1066
Author(s):  
Patrick R. Saucer
Keyword(s):  
United States ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Death Rate ◽  
The United States ◽  
Chronic Liver ◽  
Death Instinct ◽  
Death Rates ◽  
Per Capita

In reporting the accident death rate and the chronic liver disease death rate for 1980, the Bureau of the Census divided the United States into nine areas. To test Tabachnick and Klugman's hypothesis that the amount of death instinct per capita remains constant across regions, the 1980 death rates for accidents and chronic liver disease were correlated. Contrary to earlier studies, the present study gave support for Tabachnick and Klugman's hypothesis.

V.—The Decline of the Birth-Rate : Regularities Revealed by an Analysis of the Rates Observed in Certain European Countries

1939 ◽  
Vol 58 ◽  
pp. 55-72 ◽  
Author(s):  
R. S. Barclay ◽  
W. O. Kermack
Keyword(s):  
Death Rate ◽  
Birth Rate ◽  
Age Distribution ◽  
Crude Birth Rate ◽  
Developed Countries ◽  
Vital Statistics ◽  
Annual Number ◽  
Age Group ◽  
Death Rates ◽  
The World

During recent decades the vital statistics of the more developed countries of the world have exhibited two outstanding features: the first is a decline in the death‐rate, and the second a similar decline in the birth‐rate, the latter setting in some time after the former. It is generally realised that, for an adequate study of the changes involved, it is necessary, not merely to consider the crude death‐ and birth‐rates—that is, the number of deaths and births respectively per 1000 inhabitants—but also to take into account the age distribution of the population. In the case of death‐rates, for instance, it is important to know the specific death‐rates for each age-group—that is to say, for example, the annual number of deaths of persons aged twenty, per 1000 individuals of that particular age. In the same way the crude birth‐rate can only be properly interpreted when analysed in reference to the age of the mothers.

scholarly journals Increasing Firearm Deaths in The Youngest Americans: Ecologic Correlation with Firearm Prevalence

2019 ◽  
Author(s):  
Archie Bleyer ◽  
Stuart Siegel ◽  
Charles R. Thomas
Keyword(s):  
Death Rate ◽  
Causes Of Death ◽  
Average Rate ◽  
The United States ◽  
Mortality Data ◽  
Age Group ◽  
Background Checks ◽  
Rate Of Increase ◽  
Background Check ◽  
The U.S

ABSTRACTBackgroundIn the United States (U.S.), the overall death rate in 1-4 year-olds had been steadily declining until 2011, after which it ceased to improve. To understand this trend reversal, we investigated trends in the causes of their deaths.MethodsMortality data were obtained from the U.S. Centers for Disease Control and Institute for Health Metrics and Evaluation, firearm background check data from the National Instant Criminal Background Check System, and civilian firearm prevalence from the Small Arms Survey.FindingsIn 1-4 year-olds, the rate of fatal firearm accidents during 2002-2017 increased exponentially at an average rate of 6.0%/year (p=0.0003). The rate of increase was the greatest of all evaluable causes of death in the age group. Both the rate increase and most recent absolute rate in firearm accidental deaths in young children were correlated with the concurrent corresponding rate of firearm background checks (p = 0.0002 and 0.003, respectively). Also, the firearm accidental death rate in countries with high civilian firearm prevalence was correlated with the number of guns per civilian population (p=0.002).InterpretationPrior to 2004, the childhood firearm death rate did not increase during the Federal Assault Weapons Ban. Since 2004 when the Ban ended, the steadily increasing rate of sales and concomitant availability of, and access to, firearms in the U.S. has been associated with an increase in fatal firearm accidents in its youngest children. The acceleration of firearm deaths and injuries among young Americans requires urgent, definitive solutions that address firearm prevalence.FundingNo external funding.KEY POINTSQuestionIn the U.S., how has the escalation of both firearm sales and firearm death rates affected the country’s youngest population?FindingsWhile the steadily increasing rate of sales and concomitant availability of, and access to, firearms in the U.S. has increased since 2004, fatal firearm accidents in 1 to 4 year-olds increased exponentially and at a rate greater than all other evaluable causes of death in the age group.InterpretationThe ominous acceleration of firearm deaths and injuries among young Americans requires urgent, definitive solutions from multiple stakeholders to effectively reduce firearm access.

scholarly journals Not One Pandemic: A Multilevel Mixture Model Investigation of the Relationship Between Poverty and the Course of the COVID-19 Pandemic Death Rate in the United States

2021 ◽  
Vol 6 ◽  
Author(s):  
Holmes Finch ◽  
Maria E. Hernández Finch ◽  
Katherine Mytych
Keyword(s):  
United States ◽  
Mixture Model ◽  
Ethnic Diversity ◽  
Death Rate ◽  
Access To Health Care ◽  
Health Care Services ◽  
The United States ◽  
Rapid Decline ◽  
Death Rates ◽  
Random Intercept

The COVID-19 pandemic, which began in China in late 2019, and subsequently spread across the world during the first several months of 2020, has had a dramatic impact on all facets of life. At the same time, it has not manifested in the same way in every nation. Some countries experienced a large initial spike in cases and deaths, followed by a rapid decline, whereas others had relatively low rates of both outcomes throughout the first half of 2020. The United States experienced a unique pattern of the virus, with a large initial spike, followed by a moderate decline in cases, followed by second and then third spikes. In addition, research has shown that in the United States the severity of the pandemic has been associated with poverty and access to health care services. This study was designed to examine whether the course of the pandemic has been uniform across America, and if not how it differed, particularly with respect to poverty. Results of a random intercept multilevel mixture model revealed that the pandemic followed four distinct paths in the country. The least ethnically diverse (85.1% white population) and most rural (82.8% rural residents) counties had the lowest death rates (0.06/1000) and the weakest link between deaths due to COVID-19 and poverty (b = 0.03). In contrast, counties with the highest proportion of urban residents (100%), greatest ethnic diversity (48.2% nonwhite), and highest population density (751.4 people per square mile) had the highest COVID-19 death rates (0.33/1000), and strongest relationship between the COVID-19 death rate and poverty (b = 46.21). Given these findings, American policy makers need to consider developing responses to future pandemics that account for local characteristics. These responses must take special account of pandemic responses among people of color, who suffered the highest death rates in the nation.

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