scholarly journals Prevalence and associated factors of perinatal asphyxia in newborns admitted to neonatal intensive care unit at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Addisu Ginbu Dubie ◽  
Mehretie Kokeb ◽  
Abraham Tarkegn Mersha ◽  
Chilot Desta Agegnehu

Abstract Background Perinatal asphyxia is one of the leading causes of neonatal mortality and morbidity in Ethiopia. Understanding associated factors of perinatal asphyxia are important to identify vulnerable groups and to improve care during the perinatal period. Thus, this study aimed to assess the prevalence and associated factors of perinatal asphyxia among newborns admitted to NICU at the Gondar University Comprehensive Specialized Hospital Northwest Ethiopia, Ethiopia. Method Institutional based cross-sectional study was conducted on 364 newborns from November 2018 - August 2019. Data was collected using a structured and pre-tested questionnaire. It was then cleaned, coded, and entered using EPI INFO version 7, then analyzed with SPSS statistics version 20.0. Binary logistic regression analysis was used to identify variables with p < 0.2. An adjusted odds ratio (AOR) with a 95% CI and P-value of <0.05 was used to identify significantly associated variables with perinatal asphyxia. Result The prevalence of perinatal asphyxia in this study was 19.8, 95%CI (15.9, 24.2). Absence of maternal formal education (AOR = 4.09, 95%CI: 1.25, 13.38), pregnancy-induced hypertension (AOR = 4.07, 95%CI: 1.76, 9.40), antepartum hemorrhage (AOR = 6.35, 95%CI: 1.68, 23.97), prolonged duration of labor (AOR = 3.69, 95%CI: 1.68, 8.10), instrumental delivery (AOR = 3.17, 95%CI: 1.22, 8.21), and meconium-stained amniotic fluid (AOR = 4.50, 95%CI: 2.19, 9.26) were significantly associated with perinatal asphyxia. Conclusion The prevalence rate of perinatal asphyxia in this study was comparable to other resource poor countries. The absence of maternal formal education, pregnancy-induced hypertension, and Antepartum hemorrhage, prolonged duration of labor, Instrumental assisted delivery, and meconium-stained amniotic fluid was having significant association with perinatal asphyxia in this study.

Author(s):  
Richa Rathoria ◽  
Ekansh Rathoria ◽  
Utkarsh Bansal ◽  
Madhulika Mishra ◽  
Ila Jalote ◽  
...  

Background: The objective is to identify the risk factors of Meconium stained deliveries and evaluate the perinatal outcomes in Meconium Stained deliveries.Methods: This prospective observational study included those pregnant women who had completed 37 weeks of gestation, with singleton pregnancies with cephalic presentations and with no known fetal congenital anomalies. Among these, we selected 110 cases with Meconium stained amniotic fluid and they were compared with 110 randomly selected controls.Results: Regular antenatal visits were seen in 22.73 % of the cases while 77.27% cases had no previous visit. Majority of cases were primigravida and gestational ages of >40 weeks was seen in 55.45 % cases. 19.09% cases had meconium staining among pregnancies complicated with pregnancy induced hypertension, as compared to those among controls (5.45%). Fetal heart rate abnormalities were seen in 29.09% cases, and statistically significant fetal bradycardia was seen in cases. Caesarean section rates were nearly double in cases (54.55%). Poor perinatal outcome was found in cases as seen in results by low Apgar score (<7) at 1 minute and 5-minute, higher incidence of birth asphyxia, Meconium Aspiration Syndrome and increased NICU admission as compared to that among controls.Conclusions: Meconium stained amniotic fluid is more commonly associated with higher gestational age >40 weeks, pregnancy induced hypertension and fetal bradycardia, increased cesarean section rates, low APGAR score and higher incidence of birth asphyxia and NICU admissions. Meconium aspiration syndrome was associated with early neonatal death.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Gdiom Gebreheat ◽  
Tesfay Tsegay ◽  
Dessalegn Kiros ◽  
Hirut Teame ◽  
Natnael Etsay ◽  
...  

Perinatal asphyxia is one of the most important causes of morbidity and mortality in neonates. Perinatal asphyxia occurs in association with maternal, fetal, and maternofetal factors. However, the magnitude and associated factors of perinatal asphyxia are not well studied in Tigray, Ethiopia. Therefore, our study is conducted to determine the prevalence and factors associated with perinatal asphyxia among neonates in general hospitals of Tigray. An observational hospital-based cross-sectional study was conducted in randomly selected general hospitals. A semistructured questionnaire was used to collect data from 421 randomly selected neonates with their mothers and medical records. The data was entered into epidata version 3.5 and exported to Statistical Package for Social Sciences (SPSS) version 20 for analysis. Finally, the presence of an association between a dependent variable and an independent variables has been declared at P-value ≤0.05, or adjusted odds ratio (AOR), 95% confidence interval (CI). Accordingly, the result of this study showed that the prevalence of perinatal asphyxia among the selected general hospitals was 22.1%. Neonates born with cesarean section are seven times more likely to have perinatal asphyxia than those who are born spontaneously through the vagina (AOR, 6.97; CI (2.87-16.93)). In addition, neonates who are born meconium stained are 8.55 times more likely to have perinatal asphyxia than those who had not stained with meconium (AOR, 8.55; CI (4.20-17.39)). Neonates who are weighed less than 2.5 kg are 12.75 times more likely to have perinatal asphyxia than those who are weighed 2.5-4 kg (AOR, 12.75; CI (4.05-40.08)). Prolonged duration of labour was also associated statistically with perinatal asphyxia (AOR, 3.33, CI (1.32-8.38)). In conclusion, the magnitude of perinatal asphyxia in general hospitals of Tigray remains high. Low birth weight, meconium-stained amniotic fluid, cesarean section, and prolonged maternal labour have been associated with perinatal asphyxia.


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Kahsay Gebreslasie

Background. The birth of a preterm infant has a greater risk of developmental disabilities, health, and growth problems than infants born at full term. The main aim of this study was to assess the prevalence and associated factors of preterm birth Northwest Ethiopia, Gondar town health institutions. Methods. Facility based cross section study was undertaken. Systematic sampling was used to select 540 study participants. Both bivariate and multiple logistic regression were fitted. Variables with p value < 0.05 and 95% CI in multivariate were considered statistically significant. Result. This study showed that 4.4% from the total 540 mothers gave a preterm birth. The covariates of pregnancy induced hypertension (AOR 5.36 (95% CI 1.8, 15.96)) and being HIV positive (AOR 3.4 (95% CI 1.25, 9.2)) were found to be significantly associated with preterm birth. Conclusion. The main factors for preterm birth were pregnancy induced hypertension and being HIV positive. Therefore, still efforts have to be made to decrease the prevalence of preterm birth and for timely management of pregnancy induced hypertension and identifying pregnant women at the risk of preterm delivery like HIV positive women and proving quality of healthcare may decrease the rate of preterm birth and its consequences.


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Tariku Gebre Haile ◽  
Eshetu Haileselassie Engeda ◽  
Abdella Amano Abdo

Background. In many studies, compliance with standard precautions among healthcare workers was reported to be inadequate.Objective.The aim of this study was to assess compliance with standard precautions and associated factors among healthcare workers in northwest Ethiopia.Methods.An institution-based cross-sectional study was conducted from March 01 to April 30, 2014. Simple random sampling technique was used to select participants. Data were entered into Epi info 3.5.1 and were exported to SPSS version 20.0 for statistical analysis. Multivariate logistic regression analyses were computed and adjusted odds ratio with 95% confidence interval was calculated to identify associated factors.Results.The proportion of healthcare workers who always comply with standard precautions was found to be 12%. Being a female healthcare worker (AOR [95% CI] 2.18 [1.12–4.23]), higher infection risk perception (AOR [95% CI] 3.46 [1.67–7.18]), training on standard precautions (AOR [95% CI] 2.90 [1.20–7.02]), accessibility of personal protective equipment (AOR [95% CI] 2.87 [1.41–5.86]), and management support (AOR [95% CI] 2.23 [1.11–4.53]) were found to be statistically significant.Conclusion and Recommendation.Compliance with standard precautions among the healthcare workers is very low. Interventions which include training of healthcare workers on standard precautions and consistent management support are recommended.


2021 ◽  
pp. 48-50
Author(s):  
Neha Agarwal ◽  
Samta Bali Rathore ◽  
Shivani Baberwal-

BACKGROUND: Occurance of meconium-stained amniotic uid (MSAF) during labour may be considered as a measure for prediction of poor fetal outcomes such as meconium aspiration syndrome and perinatal asphyxia ,resulting in perinatal as well as neonatal morbidity and mortality. It constitutes about 5% of deliveries with meconium stained amniotic uid and death results in about 12% of infants with MAS. METHODS: 40 cases of meconium stained liquor detected after spontaneous or artical rupture of membranes taken during labour from june 2020 to december 2020 and their outcome in terms of mode of delivery(whether vaginal delivery or lower segment caesarean section) and fetal outcome and associated maternal high risk were studied RESULT: Anemia was co existant in around 15%, pregnancy induced hypertension(PIH) in 25%and premature rupture of membrane in 10%.Pregnancies complicated with Pregnancy induced hypertension had signicant higher rate of meconium stained liquor among all cases. Caesarean Section was commonly performed in meconium stained amniotic uid cases and accounted for about 65%of all cases. CONCLUSIONS: Meconium Stained amniotic uid increases the chances of caesarean rates,leading to birth asphyxia ,Meconium Aspiration Syndrome and hence increases the chances of neonatal intensive unit admission.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Tadesse Belayneh ◽  
Mulat Adefris ◽  
Gashaw Andargie

Background.Early booking of antenatal care (ANC) is regarded as a cornerstone of maternal and neonatal health care. However, existing evidence from developing countries indicate that lots of pregnant woman begin ANC booking lately.Objective.It was aimed to assess timing of ANC booking and associated factors among pregnant women attending ANC clinic at University of Gondar Hospital, 2013.Methods.An institution based cross-sectional study design was used to collect data with a face-to-face interview technique. Bivariate and multivariate analysis was used to identify associated factors for early ANC visit using SPSS version 20.Results.From total women (N = 369) interviewed, 47.4% were timely booked. Mothers with younger age (AOR = 3.83, 95% CI: 1.89, 10.53), formal education (AOR = 1.06, 95% CI: 1.03, −7.61), previous early ANC visit (AOR = 2.39, 95% CI: 2.23, 9.86), and perceived ANC visit per pregnancy of four and greater were significantly associated with early ANC visit.Conclusions.Although late booking is a problem in this study, previous early utilization of ANC visit favors current timely booking. This indicates that the importance of early booking was appropriately addressed from previous visits. Counseling of timely booking during ANC visit should be strengthened. Moreover, empowering through education is also recommended.


1970 ◽  
Vol 29 (1) ◽  
Author(s):  
Tesfaye Abera Gudeta ◽  
Tilahun Mekonnen Regassa

BACKGROUND: Disorders of pregnancy induced hypertensive are a major health problem in the obstetric population as they are one of the leading causes of maternal and perinatal morbidity and mortality. The World Health Organization estimates that at least one woman dies every seven minutes from complications of hypertensive disorders of pregnancy. The objective of this study is to assess pregnancy induced hypertension and its associated factors among women attending delivery service at Mizan-Tepi University Teaching Hospital, Gebretsadikshawo Hospital and Tepi General Hospital.METHODS: A health facility based cross-sectional study was carried out from October 01 to November 30/2016. The total sample size (422) was proportionally allocated to the three hospitals. Systematic sampling technique was used to select study participants. Variables with p-value of less than 0.25 in binary logistic regression were entered into the multivariable logistic regression to control cofounding. Odds ratio with 95% confidence interval was used. P-value less than 0.05 was considered as statistically significant.RESULTS: The prevalence of pregnancy induced hypertension was 33(7.9%); of which 5(15.2%) were gestational hypertension, 12 (36.4%) were mild preeclampsia, 15(45.5%) were severe preeclampsia and 1 (3%) eclampsia. Positive family history of pregnancy induced hypertension [AOR5.25 (1.39-19.86)], kidney diseases (AOR 3.32(1.04-10.58)), having asthma [AOR 37.95(1.41-1021)] and gestational age (AOR 0.096(0.04-.23)) were predictors of pregnancy induced hypertension.CONCLUSION: The prevalence of pregnancy induced hypertension among women attending delivery service was 7.9%. Having family history of pregnancy induced hypertension, chronic kidney diseases and gestational age were predictors of pregnancy induced hypertension. 


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