scholarly journals Environmental assessment of pediatric Lead exposure in Tehran; a prospective cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hedieh Ahangar ◽  
Afsoon Karimdoost ◽  
Amir Salimi ◽  
Maryam Akhgari ◽  
Scott Phillips ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lead Poisoning ◽  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Industrial Areas ◽  
Floor Dust ◽  
House Floor

Abstract Background Ingestion and inhalation are common routes of exposure for lead in humans. Developing countries still have unacceptably high rates of lead toxicity, especially in children. Studies on probable risk factors of lead poisoning in Iranian children are insufficient. In this study, we aimed to evaluate possible environmental factors in children with high blood lead concentrations living in Tehran and neighboring cities. Methods In a prospective cross-sectional study between March 2018 and March 2019 we followed all children referred from two pediatric gastrointestinal clinics with blood lead level (BLL) > 5 μg/dL in metropolitan Tehran to investigate possible environmental risk factors in their home. Household specimens including scratched wall paint, house floor dust, windowsill dust, tap water, and consumed spice were evaluated using atomic absorption method to detect lead concentrations. Epidemiological and environmental data collected through in-depth interviews with parents/guardians. Industrial areas were defined based on municipality maps on industrial places. Results Thirty of 56 parents/guardians with BLL > 5 μg/dL agreed to be followed through environmental investigation. The only categorical statistically significant risk factor was a history of lead poisoning in the family and living in an industrial zone. There was a positive correlation between BLL and interior windowsills dust lead level, r = 0.46, p = 0.01. Scratched paint lead level and BLL showed a significant positive correlation, r = 0.50, p = 0.005. House floor dust lead level (median = 77.4, p < 0.001) and interior windowsill dust lead level (median = 291, p = 0.011) were both significantly higher than the environmental protection agency (EPA) standards of 40 μg/ft2, 250 μg/ft2. Interior windowsill dust lead concentrations were significantly higher in industrial areas (p = 0.026). Conclusion Children’s playing environment should be cleaned more often to reduce dust. Moreover, specific rules may need to be implemented for paint lead concentrations and air pollution, especially in industrial areas.

scholarly journals Examining the relationship between blood lead level and stunting, wasting and underweight- A cross-sectional study of children under 2 years-of-age in a Bangladeshi slum

PLoS ONE ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. e0197856 ◽  
Author(s):  
Mohammad Jyoti Raihan ◽  
Emily Briskin ◽  
Mustafa Mahfuz ◽  
M. Munirul Islam ◽  
Dinesh Mondal ◽  
...  
Keyword(s):  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

scholarly journals Investigation into the Prevalence of Cryptosporidium Infection in Calves among Small-Holder Dairy and Traditional Herds in Tanzania

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Emanuel S. Swai ◽  
Luuk Schoonman
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
High Prevalence ◽  
Level Information ◽  
Independent Risk Factors ◽  
House Floor ◽  
Small Holder ◽  
Structured Questionnaire

A cross-sectional study was conducted to determine prevalence and risk factors of cryptosporidiosis in bovine from two contrasting production system in and around Tanga municipality between May 2003 and January 2004. The study populations comprised 117 calves aged ≤3 months, randomly selected from 44 smallholders dairy and traditional managed herds, respectively. Individual calf and herd-level information was collected using a structured questionnaire and feacal samples were screened forCryptosporidiumspp oocysts using the modified Ziehl-Neelsen method. Overall, 35% of the calves in the study were sheddingCryptosporidiumspp oocysts, with at least one positive calf detected in 54.5% of herds. Independent risk factors for cryptosporidiosis were: age ≥1 to ≤2 months and level of cleanness of calf house floor categorized as dirty (). Similarly an increases risk ofCryptosporidiumspp infection was found in calves from smallholder dairy units compared to traditional herds (). The finding highlights thatCryptosporidiumspp is prevalent among calves in the area under study. The high prevalence of cryptosporidiosis detected in this study suggests that it may have a significant impact on livestock industry and that the close interaction between cattle and human may play a role in zoonotic transmission to humans.

Relationship Between Blood Lead and Nutritional Factors in Preschool Children: A Cross-sectional Study

PEDIATRICS ◽  
1996 ◽  
Vol 97 (1) ◽  
pp. 74-78
Author(s):  
Susan R. Lucas ◽  
Mary Sexton ◽  
Patricia Langenberg
Keyword(s):  
Preschool Children ◽  
Dietary Fat ◽  
Lead Level ◽  
Caloric Intake ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Nutritional Factors ◽  
Total Caloric Intake

Objective. The purpose of this study was to assess the relationships between selected nutritional factors and blood lead levels of preschool children. Methodology. Data on 296 children, aged 9 to 72 months, who were cared for at the University of Maryland at Baltimore Pediatric Ambulatory Center were examined in this cross-sectional study. Nutritional status, socioeconomic aspects, medical history, and potential sources of lead exposure were assessed. Blood samples were evaluated for levels of blood lead, serum iron (ferritin), free erythrocyte photoporphyrin, calcium, and hematocrit. Results. The average blood lead level was 11.4 µg/dL. Multicollinearity of nutritional factors was addressed using regression techniques. After adjusting for confounders, significant positive associations with blood lead were found for total caloric intake (P = .01) and dietary fat (P = .05). Conclusions. The findings of this study suggest that even when behavioral and environmental exposures to lead were statistically controlled, total caloric intake and dietary fat each had an independent and significant association with the level of blood lead.

scholarly journals Blood Lead Levels and Associated Sociodemographic Factors among Children Aged 3 to 14 Years Living near Zinc and Lead Mines in Two Provinces in Vietnam

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Thi Giang Hoang ◽  
Quang Phuc Tran ◽  
Van Tung Lo ◽  
Ngoc Hai Doan ◽  
Thu Ha Nguyen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lead Level ◽  
Blood Lead ◽  
Ambient Air ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
The Body ◽  
Lead Contamination ◽  
Health Concern ◽  
Cross Sectional

Lead poisoning in children is a major public health concern worldwide, especially in developing countries. We conducted a cross-sectional study on 403 children aged from 3 to 14 years living nearly zinc–lead mining areas in two provinces in Vietnam (Bac Kan and Thai Nguyen) from 06/2016 to 10/2016 to identify risk factors for lead contamination. Results. The proportion of children with blood   lead   levels   BLLs ≥ 10  μg/dL was 80.51% in Bac Kan and 50% in Thai Nguyen; the mean blood lead level for children was 14.41 ± 9.42  μg/dL. In linear regression analyses, the body mass index was negatively associated with elevated BLLs with r = − 0.404 , p < 0.05 (95% CI: -0.801, -0.006). In multivariable regression analysis, several risk factors were associated with lead contamination including male sex ( aOR = 2.44 , 95% CI: 1.13-5.24, p = 0.02 ), play areas in Bac Kan ( aOR = 2.3 (1.02-5.17), p = 0.04 ), proximity of children’s home of less than 2 kilometers from the mine ( aOR = 2.90 (1.54-5.44), p = 0.001 ), and inattentive symptoms in Thai Nguyen ( aOR = 7.85 , 95% CI 3.49-17.69, p = 0.001 ). Environmental factors, including lead concentrations in the soil and ambient air samples in both locations, are many times higher than Vietnamese standards.

scholarly journals Blood lead concentrations among pediatric patients with abdominal pain: a prospective cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Amirhossein Hosseini ◽  
Anahita Fayaz ◽  
Hossein Hassanian-Moghaddam ◽  
Nasim Zamani ◽  
Seyed Kaveh Hadeiy ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Lead Poisoning ◽  
Lead Exposure ◽  
Motor Development ◽  
Pediatric Patients ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Organ Systems

Abstract Background Lead exposure is one of the most menacing of environmental exposures, particularly in children. Children are more susceptible to the effects of lead which manifest in many organ systems, including interference with mental and motor development. Lead poisoning can cause colicky abdominal pain. In this study, the authors sought to evaluate the prevalence of elevated blood lead level (BLL) and its contributing factors among pediatric patients presenting with abdominal pain. An epidemic of lead poisoning in adults was previously uncovered, and thus a concern for pediatric lead poisoning was raised. Methods Pediatric patients presenting to two pediatric clinics in Tehran with abdominal pain were eligible for enrollment in a descriptive prospective cross-sectional study. A predesigned questionnaire was filled for each patient by their consenting parents. The questionnaire queried demographic information, environmental, social, and other relevant parameters for lead exposure. After completion of the questionnaire, biometrics were obtained, and a blood sample was taken from each patient for measurement of BLL and complete blood count. Results A total of 187 patients were enrolled in the study. Of them, almost 20% had BLL ≥ 5 µg/dL. Univariate analysis showed that age (p = 0.002, OR 3.194, CI 95% 1.504–6.783), weight (p = 0.009, OR 2.817, CI 95% 1.266–6.269), height (p = 0.003, OR 3.155, CI 95% 1.443–6.899), and playing with both plastic and cotton toys (p = 0.03, OR 2.796, CI 95% 1.072–7.295) were significant predictors of high BLLs. Maternal level of education correlated with blood lead concentrations (p = 0.048, OR 2.524, CI 95% 1.006–6.331). Conclusions A clinically significant number of cases of abdominal pain may have high BLLs. Specific attention should be paid to children presenting with abdominal pain, especially due to the detrimental effects of lead on their mental and motor development.

scholarly journals Association between blood lead level and risk of stroke in Korean adults: a cross-sectional study in the Korea National Health and Nutrition Examination Survey 2008–2013

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e035725
Author(s):  
Minkyeong Kim ◽  
Sang-Moon Yun ◽  
Jihyun Jeong ◽  
Chulman Jo ◽  
Young Ho Koh
Keyword(s):  
Blood Lead Level ◽  
Lead Concentration ◽  
Lead Level ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
High Level ◽  
Level Group

ObjectivesAlthough lead is a potential risk factor for cardiovascular diseases such as stroke, research on this association in the Korean population remains limited. Therefore, we aimed to investigate the association between lead level and stroke in Korean adults.DesignA population-based cross-sectional study.SettingThe Korea National Health and Nutrition Examination Survey 2008–2013, which enrolled a representative sample of the Korean population.ParticipantsWe excluded participants younger than 20 years, missing weight data, pregnant or lactating, and missing blood lead and stroke data. A total of 11 510 participants were included in this analysis.Primary and secondary outcome measurementThe participants were classified by blood lead concentration into the low-level (≤2.189 µg/dL, n=5756) and high-level (>2.189 µg/dL, n=5754) groups. The main outcome, stroke, was assessed by information from physician diagnosis, prevalence of stroke or treatment for stroke. The ORs and 95% CIs were calculated to evaluate the association between blood lead level and stroke using multivariate logistic regression analysis.ResultsAlthough blood lead level was not significantly associated with stroke (OR: 1.30, 95% CI: 0.66–2.58) in the multivariate-adjusted model, in individuals with hypertension, the high-level group was 2.36-fold higher odds of stroke (OR: 2.36, 95% CI: 1.02–5.44) compared to that in the low-level group. No association was observed in individuals with normotension (OR: 0.42, 95% CI: 0.13–1.38, p for interaction=0.007).ConclusionThe association between blood lead concentration and stroke may be influenced by hypertension status. Our findings suggest the need for closer attention to lead exposure in patients with hypertension.

scholarly journals Risk factors for children’s blood lead levels in metal mining and smelting communities in Armenia: a cross-sectional study

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Ruzanna Grigoryan ◽  
Varduhi Petrosyan ◽  
Dzovinar Melkom Melkomian ◽  
Vahe Khachadourian ◽  
Andrew McCartor ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
Blood Lead Levels ◽  
Sectional Study ◽  
Metal Mining ◽  
Cross Sectional ◽  
Lead Levels ◽  
Mining And Smelting

PRRSV: Risikofaktoren und Herdenprävalenz in Deutschland

2019 ◽  
Vol 47 (02) ◽  
pp. 132-132
Author(s):  
Sebastian Ganz
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Respiratory Syndrome Virus ◽  
Sectional Study ◽  
Cross Sectional ◽  
Klinische Symptome

Nathues C, Janssen E, Duengelhoef A et al. Cross-sectional study on risk factors for Porcine Reproductive and Respiratory Syndrome virus sow herd instability in German breeding herds. Acta Vet Scand 2018; 60 (1): 1–8 In mit PRRSV (Porcine Reproductive and Respiratory Syndrom Virus) infizierten Schweinebeständen zeigen die Tiere oftmals ernsthafte klinische Symptome. Die Schwere der Symptomatik hängt von der Virulenz der jeweiligen Virusstämme ab. Deshalb ist die Impfung gegen diesen Erreger sinnvoll und wird empfohlen, auch wenn sie nicht immer klinische Fälle verhindert bzw. das Virus vollends eliminiert. Aufgrund dessen rückt die Prävention durch Verbesserung der innerbetrieblichen Abläufe zunehmend in den Fokus. Um solche Maßnahmen erfolgreich etablieren zu können, ist es wichtig, den epidemiologischen Status der Herde und mögliche Risikofaktoren zu kennen. Ziel der Studie war deshalb, die Prävalenz der Infektion in Sauenbetrieben in Norddeutschland zu eruieren und verschiedene Arbeitsabläufe hinsichtlich des Risikos der Erregerverbreitung zu untersuchen.

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