scholarly journals Research progress on quality assurance of genuine Chinese medicinal in Sichuan

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Hua Luo ◽  
Yi Zhao ◽  
Hua Hua ◽  
Yan Zhang ◽  
Xiaobo Zhang ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Chinese Medicine ◽  
Quality Evaluation ◽  
Technology Development ◽  
Wide Distribution ◽  
Research Progress ◽  
High Quality ◽  
Ecological Protection ◽  
Medicine Quality

AbstractThe genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a comprehensive standard for evaluating the quality of Chinese medicinal materials. The newest data from the Fourth National Survey of Chinese Medicinal Resources showed that Sichuan Province has 7290 types of Chinese medicine and 86 GCM, both ranking highly in China. The characteristics like diverse species, wide distribution, higher yield, and good quality are considered as advantages of geo-herbals grown in Sichuan. Resources guarantee and high-quality development of those medicine materials make a difference in local Chinese medicine quality promotion and Chinese medicine industry and technology development to serve the public's needs, assist targeted poverty alleviation, and strengthen ecological protection. This review aims to outline significant progress in the recent ten years regarding regionalization, germplasm resources, and quality evaluation around the quality assurance of GCM in Sichuan, China.

scholarly journals Basic research in the context of the development of medical substances and technologies

2018 ◽  
pp. 84-86
Author(s):  
Л.В. Кузнецова ◽  
Л.Ю. Бахтина ◽  
И.Ю. Малышев
Keyword(s):  
Experimental Design ◽  
Technology Development ◽  
Scientific Research ◽  
Basic Research ◽  
Pharmaceutical Companies ◽  
High Quality ◽  
Pharmacological Research ◽  
Design And Methods

В кратком обзоре обсуждаются задачи фармацевтических компаний, и вопросы о наиболее рациональном соотношении скорости, стоимости и качества процесса разработки лекарств и технологий (DDD). Делается заключение, что экспериментальный дизайн и методы медико-фармакологических исследований должны разрабатываться на основании современных принципов и представлений о содержании этапов DDD, с особым акцентом на высокое качество научных исследований на этапе открытия. This brief review discusses challenges of pharmaceutical companies and issues of the most rational relationship between the speed, cost, and quality of the process for drug and technology development (DTD). It was concluded that the experimental design and methods of medical and pharmacological research should be developed on the basis of modern principles and ideas about the essence of DTD stages with a particular emphasis on the high quality of scientific research at the stage of discovery.

scholarly journals Building a high quality data linkage spine using a targeted approach to clerical review

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Nadine Wiggins ◽  
Brian Stokes
Keyword(s):  
Quality Assurance ◽  
Data Linkage ◽  
Quality Data ◽  
High Confidence ◽  
Software Module ◽  
High Quality ◽  
Confidence Levels ◽  
Lower Confidence ◽  
Linkage Quality

ABSTRACTObjectivesThe Tasmanian Data Linkage Unit (TDLU) was established through the University of Tasmania in 2011 with the first dataset imported to its Master Linkage Map (MLM) during 2014. Tasmania an island state of Australia, has a population of approximately 516,000. From the TDLU’s earliest inception, it was deemed important to build a high quality linkage spine comprising key administrative data representative of significant state health and related datasets to support quality population level research.ApproachThe TDLU has embraced a model of continual quality and process enhancement as a determined strategy to support ongoing business improvement. Initial linkage approaches utilised ‘traditional’ methods of reviewing record pairs within an upper and lower confidence range. This approach resulted in false record pairs with high confidence levels being linked (false positives) and true record pairs at lower confidence levels not linked (false negatives). To improve linkage quality, the TDLU has continually refined and modified its clerical review methodology with a specialist software module developed to identify specific record attributes within groups that require the group to be manually reviewed and resolved. A range of SQL queries have also been developed to identify incorrect links and further enhance the linkage quality of the MLM.ResultsThe linkage quality tools implemented have led to improved clerical review and quality assurance processes which in turn have increased the overall quality of the linkage spine. The ‘targeted’ method of clerical review provides easy identification of false positive records, particularly those with high confidence scores such as twins and husband/wife combinations. The review of groups at lower confidence levels has minimised the rate of false negative pairs however further refinement of tools is required to minimise the time spent on reviewing these groups. The clerical review software module has equipped staff with the necessary information to make informed and timely decisions when reviewing groups of records. Detailed documentation is maintained for each linkage project providing continual feedback for system and process improvements as the linkage spine increases in size.ConclusionThe process of clerical review and quality assurance requires a commitment to continual refinement of tools and techniques resulting in a higher quality linkage spine and a reduction in the total time and resource required to link datasets.

Nondestructive Quality Evaluation From a Horticulturist's Point of View

1978 ◽  
Vol 41 (1) ◽  
pp. 63-66 ◽  
Author(s):  
W. E. BALLINGER ◽  
W. F. McCLURE ◽  
E. P. MANESS ◽  
W. B. NESBITT ◽  
D. E. CARROLL ◽  
...  
Keyword(s):  
Quality Evaluation ◽  
Fruits And Vegetables ◽  
Quality Characteristics ◽  
Point Of View ◽  
High Quality ◽  
Nondestructive Techniques ◽  
Nondestructive Quality

Application of nondestructive sorting of fruits can be direct or indirect. Direct applications involve mainly objective means of establishing grades and quality of fruits and vegetables, as well as use of light-sorting and other nondestructive means for determining when a crop should be harvested or whether it should be marketed fresh or processed immediately. Indirect applications might be termed “research” usage of nondestructive sorting. Plant breeders would find nondestructive techniques useful for rapidly evaluating quality characteristics during the development of high quality cultivars. Physiologists could utilize it to rapidly determine the effects of treatments upon the quality of the commodity. Examples of development of techniques of light-sorting of blueberries and grapes for ripeness are discussed.

scholarly journals A Sequence-Based Novel Approach for Quality Evaluation of Third-Generation Sequencing Reads

Genes ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 44 ◽  
Author(s):  
Wenjing Zhang ◽  
Neng Huang ◽  
Jiantao Zheng ◽  
Xingyu Liao ◽  
Jianxin Wang ◽  
...  
Keyword(s):  
Quality Evaluation ◽  
Training Data ◽  
Third Generation ◽  
Contig Assembly ◽  
High Quality ◽  
Promising Alternative ◽  
Third Generation Sequencing ◽  
Long Reads ◽  
Generation Sequencing

The advent of third-generation sequencing (TGS) technologies, such as the Pacific Biosciences (PacBio) and Oxford Nanopore machines, provides new possibilities for contig assembly, scaffolding, and high-performance computing in bioinformatics due to its long reads. However, the high error rate and poor quality of TGS reads provide new challenges for accurate genome assembly and long-read alignment. Efficient processing methods are in need to prioritize high-quality reads for improving the results of error correction and assembly. In this study, we proposed a novel Read Quality Evaluation and Selection Tool (REQUEST) for evaluating the quality of third-generation long reads. REQUEST generates training data of high-quality and low-quality reads which are characterized by their nucleotide combinations. A linear regression model was built to score the quality of reads. The method was tested on three datasets of different species. The results showed that the top-scored reads prioritized by REQUEST achieved higher alignment accuracies. The contig assembly results based on the top-scored reads also outperformed conventional approaches that use all reads. REQUEST is able to distinguish high-quality reads from low-quality ones without using reference genomes, making it a promising alternative sequence-quality evaluation method to alignment-based algorithms.

scholarly journals Simultaneous Determination of Six Active Compounds in Yixin Badiranjibuya Granules, a Traditional Chinese Medicine, by RP-HPLC-UV Method

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Ning Yu ◽  
ChenHui He ◽  
Gulistan Awuti ◽  
Cheng Zeng ◽  
JianGuo Xing ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Rosmarinic Acid ◽  
Quality Evaluation ◽  
Scientific Basis ◽  
Determination Method ◽  
Rp Hplc ◽  
And Control ◽  
First Time

In this study, a sensitive, precise, and accurate HPLC-UV method was developed and validated to simultaneously determine the six analytes (luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D-glucuronide, tilianin, and rosmarinic acid) in Yixin Badiranjibuya Granules, in which five analytes (i.e., luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D-glucuronide, and rosmarinic acid) were determined for the first time in Yixin Badiranjibuya Granules, the content of tilianin in Yixin Badiranjibuya Granules was reported in other literatures, and the content of tilianin in our work was higher than that of the literature reports. The quality of 11 batch samples from four different manufacturers was evaluated using the proposed determination method. The contents of the six analytes were largely different among samples from various manufacturers. Therefore, this determination method can provide a scientific basis for quality evaluation and control of Yixin Badiranjibuya Granules.

scholarly journals Am Bestehenden weiterdenken

ARCHALP ◽  
2019 ◽  
Vol 2 NS (Issue 2 Ns, July 2019) ◽  
pp. 105-113
Author(s):  
Walter Angonese
Keyword(s):  
Quality Assurance ◽  
Architectural Design ◽  
High Quality ◽  
Existing Structures ◽  
Starting Point ◽  
Awareness Raising ◽  
The Individual ◽  
The Way

Isn’t the existent always the outcome of any creative confrontation? Is such a creative discussion really out of a contextual consideration? Isn’t every context – even a purely spiritual one – part of the heritage? In his contribution, Walter Angonese reflects on the potential of the pre-existent on the architectural project. He believes in “thinking ahead” and consequently in “building on”, and that is why the question of the relevance of existing structures to architectural design has been clarified. However, he also believes that the quality of the existent can only be improved thanks to an increased habit of awareness and not only following and blaming the prescribed laws for quality assurance. This awareness raising gives responsibility to the individual within a society, but also makes him responsible for his own actions. Building in an alpine context – like any building, by the way – is therefore a question of responsibility, towards oneself and towards one’s society. If the architectural idea is built by leading it from an intuition about a cultural reflection to what one can call a real “architectural idea” (and not merely any intuition), then that is an important first step for a high-quality “continuing construction” of the existing. Only the heritage and the existent can become a meaningful starting point of the project.

An Evaluation Model of Polytechnic Teaching Quality Based on ID3 Decision Making Tree

2014 ◽  
Vol 651-653 ◽  
pp. 2437-2440 ◽  
Author(s):  
Wu Xue Jiang ◽  
Yin Zhen Zhong ◽  
Huan Liang
Keyword(s):  
Decision Tree ◽  
Quality Evaluation ◽  
Teaching Practice ◽  
Evaluation Model ◽  
Teaching Quality ◽  
Practical Significance ◽  
Research Progress ◽  
Apriori Algorithm ◽  
High Credibility

For improving the quality of vocational education evaluation validity, this paper introduces the research progress of teaching evaluation, use data mining technology to put forward a feasible model of higher vocational teaching quality evaluation, construct a decision tree has practical significance. By the method used, the traditional Apriori algorithm is improved decision tree to improve the teaching contents to the location of the second master node, reflecting the characteristics of vocational teaching practice. Case analysis indicated, the decision tree has a good operability and high credibility.

scholarly journals GMP/GACP - new standards for quality assurance of cannabis

2020 ◽  
Vol 66 (1) ◽  
pp. 91-101
Author(s):  
Mirela Ilikj ◽  
Irena Brchina ◽  
Liljana Ugrinova ◽  
Vasil Karcev ◽  
Aleksandra Grozdanova
Keyword(s):  
Quality Control ◽  
Quality Assurance ◽  
Quality Standards ◽  
Quality System ◽  
Quality Systems ◽  
High Quality ◽  
Iso Standard ◽  
Continuous Quality ◽  
Medicinal Use

In 2015, in Republic of North Macedonia, a new law for narcotics has been adopted, where the changes include legal cultivation of cannabis for medicinal use as well as legal production of cannabis extracts for medicinal use. In order to gain high quality of cannabis and cannabis products for medicinal use and to meet some quality standards that will guarantee consistency, traceability and continuous quality of the product, it is necessary to implement Quality Systems. Good quality system is ISO standard system but for cannabis for medicinal use, GACP, GMP and GLC standards are used more often. Production of cannabis for medicinal use consists of: process of cultivation where GACP standards are applicable, primary processing where GMP standards are the most important and quality control of final product regulated with GLP standard. In this review, explanation of these standards as well as overview of modes of their implementation has been made. Keywords: GxP, GMP, GACP, GLP

scholarly journals . Increasing the efficiency of casting manufacture in small-scale and single-unit production

2020 ◽  
pp. 10-14
Author(s):  
M. A. Sadokha ◽  
S. L. Rovin
Keyword(s):  
Quality Assurance ◽  
Single Unit ◽  
Small Scale ◽  
Technological Equipment ◽  
Minimal Cost ◽  
Technological Changes ◽  
High Quality ◽  
Casting Technology ◽  
Modern Engineering

Foundry is a multidisciplinary industry of engineering, providing cast blanks from various metals and alloys. The seriality of production has a great impact on the efficiency and quality of the castings being received. Single-unit and small-scale foundry production is an important part of modern engineering. Structural analysis of casting technology is presented in the article, individual technological changes are considered both in terms of impact on the efficiency of casting, and in terms of high quality assurance at minimal cost. Taking into account the need for a single-unit and small-scale casting in the fl xibility of the processes, schemes of organization of technological preparation of production and technological equipment are proposed. Examples of the equipment used are given.

Exploring Quality Assurances

2022 ◽  
pp. 26-42
Author(s):  
Vimbi Petrus Mahlangu ◽  
Mpipo Zipporah Sedio
Keyword(s):  
Higher Education ◽  
Quality Assurance ◽  
Literature Review ◽  
Higher Education Institutions ◽  
Qualitative Approach ◽  
High Quality ◽  
Education Standards ◽  
High Quality Education ◽  
Critical Requirement

The purpose of this chapter is to argue that higher education institutions (HEIs) in doing quality assurance (QA) must focus on the critical aspects of quality assurance, the need to look at the advantages, disadvantages, and challenges facing HEIs regarding quality assurance. It is assumed that institutions should carry out quality assurance and accreditation processes for stakeholders to have confidence in them. It also explains in detail what quality assurance and accreditation must entail in higher education institutions (HEIs). The need to maintain high-quality education standards becomes a critical requirement for HEIs to remain competitive in the education sector market. This chapter follows a qualitative approach in exploring quality assurance and accreditation in HEIs. Data will be collected through literature review. Quality assurance and accreditation in HEIs must aim to maintain and raise the quality of education and to guarantee the improvement of its standards.

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