scholarly journals Incidence and root causes of surgical site infections after gastrointestinal surgery at a public teaching hospital in Sudan

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Rawan Sharaf Eldein Elamein Hassan ◽  
Sarah Osman Sayed Osman ◽  
Mohamed Abdulmonem Salih Aabdeen ◽  
Walid Elhaj Abdelrahim Mohamed ◽  
Razan Sharaf Eldein Elamein Hassan ◽  
...  

Abstract Background Surgical site infections (SSIs) are common healthcare-associated infections and associated with prolonged hospital stays, additional financial burden, and significantly hamper the potential benefits of surgical interventions. Causes of SSIs are multi-factorials and patients undergoing gastrointestinal tract procedures carry a high risk of bacterial contamination. This study aimed to determine the prevalence, associated factors, and causing microorganisms of SSIs among patients undergoing gastrointestinal tract surgeries. Methods A hospital based, cross-sectional study conducted at Soba University Hospital in Khartoum, Sudan. We included all patients from all age groups attending the gastrointestinal tract surgical unit between 1st September and 31st December 2017. We collected data about the socio-demographic characteristics, risk factors of SSI, and isolated microorganisms from patients with SSIs. A Chi-square test was conducted to determine the relationship between the independent categorical variables and the occurrence of SSI. The significance level for all analyses was set at p < .05. Results A total of 80 participants were included in the study. The mean age was 51 +/- 16 years and most of the patients (67.5%) did not have any chronic illness prior to the surgical operation. Most of them (46.3%) of them underwent large bowel surgery. Twenty-two patients (27.5%) developed SSI post operatively and superficial SSI was the most common type of SSIs (81.8%). Occurrence of SSI was found to be associated with long operation time (p > .001), malignant nature of the disease (p > .001), intra-operative blood loss (p > .001), and intra-operative hypotension (p = .013). The most prevalent microorganism isolated from SSI patients was E coli (47.8%), followed by Enterococcus fecalis (13.0%) and combined Pseudomonas aeruginosa + E coli infection (13.0%). Conclusions The results showed a high prevalence of SSIs among patients attending the gastrointestinal tract surgical unit and the most prevalent microorganism isolated from them was E coli. Measures should be taken to reduce the magnitude of SSI by mitigating the identified associated factors.

2020 ◽  
Author(s):  
Rawan Sharaf Eldein Elamein Hassan ◽  
Sarah Osman Sayed Osman ◽  
Mohamed Abdulmonem Salih Aabdeen ◽  
Walid Elhaj Abdelrahim Mohamed ◽  
Razan Sharaf Eldein Elamein Hassan ◽  
...  

Abstract Background: Surgical site infections (SSIs) are common healthcare-associated infections and associated with prolonged hospital stays, additional financial burden, and significantly hamper the potential benefits of surgical interventions. Causes of SSIs are multi-factorials and patients undergoing gastrointestinal tract (GIT) procedures carry a high risk of bacterial contamination. This study aimed to determine the prevalence, associated factors, and causing microorganisms of SSIs among patients undergoing GIT surgeries.Methods: A hospital based, cross-sectional study conducted at Soba University Hospital (SUH) in Khartoum, Sudan. We included all patients from all age groups attending the GIT surgical unit at SUH between September-December 2017. We collected data about the socio-demographic characteristics, risk factors of SSI, and isolated microorganisms from patients with SSIs. Data analysis was done using the SPSS software version 20 (SPSS Inc., Chicago, IL, USA). A Chi-square test was conducted to determine the relationship between the independent categorical variables and the occurrence of SSI. The significance level for all analyses was set at p < .05.Results: A total of 80 participants were included in the study. The mean age was 51 +/- 16 years and most of the patients (67.5%) did not have any chronic illness prior to the surgical operation. Most of them (46.3%) of them underwent large bowel surgery. Twenty-two patients (27.5%) developed SSI post operatively and superficial SSI was the most common type of SSIs (81.8%). Occurrence of SSI was found to be associated with long operation time (p > .001), malignant nature of the disease (p > .001), intra-operative blood loss (p > .001), and intra-operative hypotension (p =.013). The most prevalent microorganism isolated from SSI patients was E coli (47.8%), followed by Enterococcus fecalis (13.0%) and combined Pseudomonas aeruginosa + E coli infection (13.0%).Conclusion: The results showed a high prevalence of SSIs among patients attending the GIT unit in SUH and the most prevalent microorganism isolated from them was E coli. Measures should be taken to reduce the magnitude of SSI by mitigating the identified associated factors.


2006 ◽  
Vol 27 (08) ◽  
pp. 855-862 ◽  
Author(s):  
Le Thi Anh Thu ◽  
Annette H. Sohn ◽  
Nguyen Phuc Tien ◽  
Vo Thi Chi Mai ◽  
Vo Van Nho ◽  
...  

Objectives. To determine the pathogens associated with surgical site infections (SSIs) and describe patterns of antimicrobial use and resistance in orthopedic and neurosurgical patients in a large university hospital in Vietnam. Design. Prospective cohort study. Setting. Cho Ray Hospital, Ho Chi Minh City, Vietnam. Patients. All patients who had operations during a 5-week study period. Results. Of 702 surgical patients, 80 (11.4%) developed an SSI. The incidence of SSI among orthopedic patients was 15.2% (48 of 315), and among neurosurgical patients it was 8.3% (32 of 387). Postoperative bacterial cultures of samples from the surgical sites were performed for 55 (68.8%) of the 80 patients with SSI; 68 wound swab specimens and 10 cerebrospinal fluid samples were cultured. Of these 78 cultures, 60 (76.9%) were positive for a pathogen, and 15 (25%) of those 60 cultures yielded multiple pathogens. The 3 most frequently isolated pathogens were Pseudomonas aeruginosa (29.5% of isolates), Staphylococcus aureus (11.5% of isolates), and Escherichia coli (10.3% of isolates). Ninety percent of S. aureus isolates were methicillin resistant, 91% of P. aeruginosa isolates were ceftazidime resistant, and 38% of E. coli isolates were cefotaxime resistant. All but 1 of the 702 patients received antimicrobial therapy after surgery, and the median duration of antimicrobial therapy was 11 days. Commonly used antimicrobials included aminopenicillins and second- and third-generation cephalosporins. Two or, more agents were given to 634 (90%) of the patients, and most combination drug regimens (86%) included an aminoglycoside. Conclusions. Our data indicate that the incidence of SSI is high in our study population, that the main pathogens causing SSI are gram-negative bacteria and are often resistant to commonly used antimicrobials, that the use of broad-spectrum antimicrobials after surgery is widespread, and that implementation of interventions aimed at promoting appropriate and evidence-based use of antimicrobials are needed in Vietnam.


2019 ◽  
Vol 9 (3) ◽  
Author(s):  
Duy Long Võ ◽  

Tóm tắt Đặt vấn đề: Phẫu thuật nội soi cắt dạ dày và nạo hạch mang lại nhiều lợi ích cho người bệnh. Phục hồi lưu thông ruột theo Roux - en -Y hoàn toàn bằng phẫu thuật nội soi (PTNS) theo phương pháp cắt dạ dày và ruột non trước tốn nhiều stapler, làm tăng chi phí điều trị. Mục tiêu của nghiên cứu này nhằm đưa ra kỹ thuật phục hồi lưu thông ruột hoàn toàn bằng PTNS mà không cắt ruột trước trong điều trị ung thư dạ dày. Phương pháp nghiên cứu: Đây là nghiên cứu tiền cứu, can thiệp lâm sàng. Từ tháng 6 năm 2015 đến tháng 8 năm 2016, tại khoa Ngoại Tiêu hóa, Bệnh viện Đại học Y Dược TP. HCM có 70 trường hợp ung thư dạ dày được phẫu thuật nội soi cắt dạ dày kèm nạo hạch D2 và phục hồi lưu thông ruột hoàn toàn trong ổ bụng theo Roux en Y bằng kỹ thuật không cắt ruột trước. Trong số này, có 40 trường hợp được cắt bán phần dưới dạ dày và 30 trường hợp cắt toàn bộ dạ dày. Các dữ kiện để đánh giá kết quả gồm: số lượng stapler dùng, thời gian mổ, biến chứng sau mổ và thời gian sống còn sau mổ. Kết quả: Tuổi trung bình 51,1. Thời gian mổ trung bình là 178 ± 28 phút. Số lượng stapler dùng cho 1 trường hợp cắt bán phần dưới hoặc toàn bộ dạ dày là 3, tối đa dùng 4 stapler. Tất cả trường hợp đều không còn tế bào ác tính ở bờ mặt cắt. Có 1 trường hợp (1,4%) nối lộn quai. Không có biến chứng xì, rò hay chảy máu miệng nối sau mổ. Thời gian sống còn chung sau mổ 1 và 3 năm lần lượt là 92% và 81%. Kết luận: Phục hồi lưu thông ruột theo phương pháp Roux - en -Y hoàn toàn qua PTNS cắt dạ dày và nạo hạch D2 mà không cắt ruột trước làm giảm số lượng stapler dùng và không tăng thêm biến chứng sau mổ. Thời gian sống còn sau mổ khả quan. Abstract Introduction: Gastrectomy associated with lymphadenectomy for patients with gastric cancer has great benefits. Totally intracorporeal Roux-en-Y anastomosis uses lot of staplers, and costs to patients. The aim of this study is to investigate on the effectiveness laparoscopic gastrectomy with totally intracorporeal reconstruction of gastrointestinal tract using unprecut method for gastric cancer. Material and Methods: This was a prospective interventional clinical research. From June 2015 to August 2016 at Gastrointestinal Surgery Department of UMC, 70 patients of gastric cancer were performed D2-gastrectomy with totally intracorporeal Roux-en-Y anastomosis using unprecut method. Among them, there were 40 cases of distal gastrectomy and 30 cases of total gastrectomy. The data collected were : number of staplers, operation time, post-operative complications, survival time. Results: The mean age was 51.1 years. The mean operation time was 178 +/- 28 minutes. The number of staplers per case for distal gastrectomy or total gastrectomy was 3 staplers, with maximum of 4 staplers. All cases had R0 margins. There was one case (1.4%) of misconstruction. There were no post-operative complications such as leakage or anastomotic fistular even bleeding. Overall 1-year and 3-year survival rates were 92% and 81%, respectively. Conclusion: Laparoscopic gastrectomy with totally intracorporeal reconstruction of gastrointestional tract using unprecut method for gastric cancer saved the number of staplers and not increased post-operative complications. The survival rate was satisfied. Keyword: Laparoscopic gastric


BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tomoko Takahashi ◽  
Hiroshi Nishiura

Abstract Background Surgical site infections (SSI) are the most common healthcare-associated infection, and gastrointestinal surgery is frequently followed by a high incidence of SSI. Epidemiological analysis of the temporal trends in SSI following gastrointestinal surgery has yet to be performed in Japan. Our purpose was to descriptively investigate these trends. Methods Extracting national surveillance data from the Japan Nosocomial Infections Surveillance (JANIS) system, we analyzed the frequency of SSI events following gastrointestinal surgery, which consisted of seven surgical procedures, from 2012–2017. We calculated the standardized infection ratio to compute risk-adjusted SSI frequency, and used the trend test to detect time-dependent changes. Results The frequency of SSI events, except for those associated with surgery of the upper gastrointestinal tract, revealed a decreasing time-dependent trend. The use of laparoscopic surgery increased dramatically over time (p < 0.01 for the six applicable surgical sites), while the frequency of SSI events during laparoscopic surgery remained unchanged. Conclusions The increasing use of laparoscopic surgery was identified, and the observation coincided with the decreasing trend in SSI, especially in lower gastrointestinal tract surgery. If the relationship is causal, the overall SSI incidence among previously healthy individuals is expected to decrease, because the use of laparoscopic surgery has large growth potential in Japan.


2021 ◽  
Author(s):  
Tetsu SHIMANE ◽  
Kazuyuki Koike ◽  
Shigeyuki Fujita ◽  
Hiroshi Kurita ◽  
Emiko Tanaka Isomura ◽  
...  

Abstract Background: Surgical site infections (SSI) are associated with increased morbidity and mortality. The purpose of this study was to investigate the ability of perioperative oral management (POM) to reduce the risk of SSI in abdominal surgery. Real-world data collected from 16 Japanese university hospital was reviewed. Methods: The medical records of consecutive 2,782 patients (1,750 men and 1,032 women) who underwent abdominal surgery under general anesthesia in 16 university hospitals were retrospectively reviewed. Detailed information about SSI was assessed and compared between patients with and without POM in univariate and multivariate analyses. Results: SSI were observed in 275 patients (incidence rate: 9.9%) and POM was delivered in 778 patients (28.0%). Univariate analyses revealed that diabetes mellitus, Eastern Cooperative Oncology Group (ECOG) performance status, the American Society of Anesthesiologists (ASA) classification, the surgical site, the preoperative Prognostic Nutritional Index score, POM, the extent of surgery, the operation time, and the amount of intraoperative blood loss were significantly associated with postoperative SSI (Chi-square or Mann-Whitney U-test, p <0.01). The multivariate analysis revealed that POM had significant preventative effects against postoperative SSI (estimate: -0.245, standard error: 0.080, p <0.01). The surgical site, the ASA classification, and the operation time were also significant and independent clinical predictors of SSI.Conclusion: The analysis of real-world data from 16 university hospitals revealed that, regardless of the content and degree of the problem, addition of POM has significant beneficial effects in reducing the risk of SSI in patients who undergo abdominal surgery.


2017 ◽  
pp. 103-106
Author(s):  
Minh Duc Pham

Background: Conventional three–port laparoscopic appendectomy is becoming popular for the treatment of acute appendicitis. In this report, we present the early results of a new technique of laparoscopic appendectomy conducted through a single-port. Patients and Methods: From March 2011 to October 2013, we have performed 86 operations Single Port Laparoscopic Appendectomy at Hue University Hospital and Hue Central Hospital. SILS Port (Covidien) is used, it can be performed with basic laparoscopic instruments. Results: In this study, 86 patients underwent Single-Port laparoscopic appendectomy, among them 52.33% were femele, 47.67% were male, female/male ratio was 1.09. The mean age was 33.09. An orther trocar insertion was required in 2 patients (2.33%). The mean operation time was 42.03 minutes and mean postoperative hospital stay 3.37 days. Postoperative complication occurred in 2 case (2.33%) was of omphalitis. During 2 weeks follow up, 2 case (2.33%) was of omphalitis. Conclusions: Single - port intracorporeal appendectomy is a safe, minimal invasive procedure with excellent cosmetic results. Key words: Single Port Laparoscopic Appendectomy, appendectomy


2018 ◽  
pp. 100-108
Author(s):  
Dinh Khanh Le ◽  
Dinh Dam Le ◽  
Khoa Hung Nguyen ◽  
Xuan My Nguyen ◽  
Minh Nhat Vo ◽  
...  

Objectives: To investigate clinical characteristics, bacterial characteristics, drug resistance status in patients with urinary tract infections treated at Department of Urology, Hue University Hospital. Materials and Method: The study was conducted in 474 patients with urological disease treated at Department of Urology, Hue Universiry Hospital from July 2017 to April 2018. Urine culture was done in the patients with urine > 25 Leu/ul who have symptoms of urinary tract disease or infection symptoms. Patients with positive urine cultures were analyzed for clinical and bacterial characteristics. Results: 187/474 (39.5%) patients had symptoms associated with urinary tract infections. 85/474 (17.9%) patients were diagnosed with urinary tract infection. The positive urine culture rate was 45.5%. Symptoms of UTI were varied, and no prominent symptoms. E. coli accounts for the highest proportion (46.67%), followed by, Staphycoccus aureus (10.67%), Pseudomonas aeruginsa (8,0%), Streptococcus faecali and Proteus (2.67%). ESBL - producing E. coli was 69.23%, ESBL producing Enterobacter spp was 33.33%. Gram-negative bacteria are susceptible to meropenem, imipenem, amikacin while gram positive are vancomycin-sensitive. Conclusions: Clinical manifestations of urinary tract infections varied and its typical symptoms are unclear. E.coli is a common bacterium (46.67%). Isolated bacteria have a high rate of resistance to some common antibiotics especially the third generation cephalosporins and quinolones. Most bacteria are resistant to multiple antibiotics at the same time. Gram (+) bacteria are susceptible to vancomycin, and gram (-) bacteria are susceptible to cefoxitin, amikacin, and carbapenem. Key words: urinary tract infection


2021 ◽  
Vol 10 (8) ◽  
pp. 1563
Author(s):  
Ching-Chia Li ◽  
Tsu-Ming Chien ◽  
Ming-Ru Lee ◽  
Hsiang-Ying Lee ◽  
Hung-Lung Ke ◽  
...  

Currently, over 80% of radical prostatectomies have been performed with the da Vinci Surgical System. In order to improve the aesthetic outlook and decrease the morbidity of the operation, the new da Vinci Single Port (SP) system was developed in 2018. However, one major problem is the SP system is still not available in most countries. We aim to present our initial experience and show the safety and feasibility of the single-site robotic-assisted radical prostatectomy (LESS-RP) using the da Vinci Single-Site platform. From June 2017 to January 2020, 120 patients with localized prostate cancer (stage T1–T3b) at Kaohsiung Medical University Hospital were included in this study. We describe our technique and report our initial results of LESS-RP using the da Vinci Si robotic system. Preoperative, intraoperative and postoperative patient variables were recorded. Prostate-specific antigen (PSA)-free survival was also analyzed. A total of 120 patients were enrolled in the study. The median age of patients was 68 years (IQR 63–71), with a median body mass index of 25 kg/m2 (IQR 23–27). The median PSA value before operation was 10.7 ng/mL (IQR 7.9–21.1). The median setup time for creat-ing the extraperitoneal space and ports document was 25 min (IQR 18–34). The median robotic console time and operation time were 135 min (IQR 110–161) and 225 min (IQR 197–274), respectively. Median blood loss was 365 mL (IQR 200–600). There were 11 (9.2%) patients who experienced complications (Clavien–Dindo classification Gr II). The me-dian catheter duration was 8 days (IQR 7–9), with a median of 10 days (IQR 7–11) of hospital stay. The PSA free-survival rate was 86% at a median 19 months (IQR 6–28) of follow up. Robotic radical prostatectomy using the da Vinci Single-Site platform system is safe and feasible, with acceptable outcomes.


Antibiotics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 43
Author(s):  
Robin Janssen ◽  
Frans Van Workum ◽  
Nikolaj Baranov ◽  
Harmen Blok ◽  
Jaap ten Oever ◽  
...  

Infectious complications occur frequently after esophagectomy. Selective decontamination of the digestive tract (SDD) has been shown to reduce postoperative infections and anastomotic leakage in gastrointestinal surgery, but robust evidence for esophageal surgery is lacking. The aim was to evaluate the association between SDD and pneumonia, surgical-site infections (SSIs), anastomotic leakage, and 1-year mortality after esophagectomy. A retrospective cohort study was conducted in patients undergoing Ivor Lewis esophagectomy in four Dutch hospitals between 2012 and 2018. Two hospitals used SDD perioperatively and two did not. SDD consisted of an oral paste and suspension (containing amphotericin B, colistin, and tobramycin). The primary outcomes were 30-day postoperative pneumonia and SSIs. Secondary outcomes were anastomotic leakage and 1-year mortality. Logistic regression analyses were performed to determine the association between SDD and the relevant outcomes (odds ratio (OR)). A total of 496 patients were included, of whom 179 received SDD perioperatively and the other 317 patients did not receive SDD. Patients who received SDD were less likely to develop postoperative pneumonia (20.1% vs. 36.9%, p < 0.001) and anastomotic leakage (10.6% vs. 19.9%, p = 0.008). Multivariate analysis showed that SDD is an independent protective factor for postoperative pneumonia (OR 0.40, 95% CI 0.23–0.67, p < 0.001) and anastomotic leakage (OR 0.46, 95% CI 0.26–0.84, p = 0.011). Use of perioperative SDD seems to be associated with a lower risk of pneumonia and anastomotic leakage after esophagectomy.


Author(s):  
Jahyung Kim ◽  
Sanghyeon Lee ◽  
Jeong Seok Lee ◽  
Sung Hun Won ◽  
Dong Il Chun ◽  
...  

(1) Background: Ingrown toenail is a common disorder of the toe that induces severe toe pain and limits daily activities. The Winograd method, the most widely used operative modality for ingrown toenails, has been modified over years to include wedge resection of the nail fold and complete ablation of the germinal matrix. We evaluated the outcomes of original Winograd procedure without wedge resection with electrocautery-aided matrixectomy. (2) Methods: We retrospectively analyzed the outcomes of patients who underwent surgery for ingrown toenails at a university hospital for two years from November 2015 to October 2017. Surgery was performed in 76 feet with a mean operation time of 9.34 min. (3) Results: The minimal interval from surgery to return to regular activities was 13.26 (range 7 to 22) days. Recurrence and postoperative wound infections were found in 3 (3.95%) and 2 (2.63%) patients, respectively. Evaluation of patient satisfaction at one-year follow-up showed that 40 (52.63%) patients were very satisfied, 33 (43.42%) were satisfied, 3 (3.95%) were dissatisfied, and none of them were very dissatisfied. The average follow-up duration was 14.66 (range 12 to 25) months. (4) Conclusions: Therefore, it is believed that this less-invasive and simple procedure could be easily performed by clinicians, with satisfactory patient outcomes.


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