scholarly journals Skin hyperpigmentation and its treatment with herbs: an alternative method

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Prity Rathee ◽  
Sunil Kumar ◽  
Dinesh Kumar ◽  
Beena Kumari ◽  
Savita S. Yadav
Keyword(s):  
Sun Exposure ◽  
Skin Condition ◽  
Main Body ◽  
Skin Hyperpigmentation ◽  
Number Of Patients ◽  
Different Types ◽  
Common Skin ◽  
Sun Spots ◽  
Multiple Treatments ◽  
Surrounding Areas

Abstract Background With an increasing number of patients, those who are facing a lot of skin-related complaints, often referred to as skin of pigmentation patients, are on the rise. Among all the most common complaints in patients with skin of color is hyperpigmentation. So, there is need of herbal formulation for treatment of hyperpigmentation. Main body This review article addresses the different types of hyperpigmentation, causes, and its treatment with herbs for the management of the skin hyperpigmentation. As uneven pigmentation of skin or hyperpigmentation is a common skin condition, which occurs when the skin produces more melanin. This can make spots or patches of skin appear darker than surrounding areas. Some forms of hyperpigmentation with post-inflammatory, melasma, and sun spots are more likely to affect areas of face, arms, and legs due to sun exposure and injury. Although the availability of multiple treatments for the condition which leads to some adverse effects, hyperpigmentation continues to present skin care management challenges for dermatologists. Conclusion Some plants and phytoconstituents, e.g., Azadirachta indica, Glycyrrhiza glabra, Panax ginseng and genistein, ellagic acids, quercetin, are very useful in herbal cosmetic as anti-hyperpigmentry agents in cosmetic industries. Some of flavonoids and triterpenoids present in plants also show their effect as antioxidant and skin whitening agents. It is expected that this review will compile and improve the existing knowledge on the potential utilization of herbs for the treatment of skin hyperpigmentation.

scholarly journals Guidelines for the management of Acne Vulgaris

2017 ◽  
Vol 59 (2) ◽  
pp. 24-29
Author(s):  
Werner Sinclair
Keyword(s):  
Successful Treatment ◽  
Acne Vulgaris ◽  
Skin Condition ◽  
Algorithmic Approach ◽  
Medical Practitioners ◽  
Different Types ◽  
Common Skin ◽  
General Medical Practitioners

Background: Acne vulgaris is a very common skin condition that, in the vast majority, can and should be effectively managed by general medical practitioners. Several guideline documents for management thereof exist and there is an overwhelmingly large, confusing literature bank available on the topic. Methods: This article summarises and simplifies the main guideline documents that have been published over the last few years to present the results in an algorithmic approach to the treatment of the different types and grades of acne. Disclaimer: Adherence to these guidelines will not ensure successful treatment in every situation and should not be deemed inclusive of all proper methods of care or exclusive of other methods of care reasonably directed to obtaining the same results.

scholarly journals The need for widely available genomic testing in rare eye diseases: an ERN-EYE position statement

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Graeme C. Black ◽  
◽  
Panagiotis Sergouniotis ◽  
Andrea Sodi ◽  
Bart P. Leroy ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Rare Diseases ◽  
Eye Diseases ◽  
Reference Network ◽  
Genomic Testing ◽  
Main Body ◽  
National Plan ◽  
Member States ◽  
Technological Advances ◽  
Number Of Patients

Abstract Background Rare Eye Diseases (RED) are the leading cause of visual impairment and blindness for children and young adults in Europe. This heterogeneous group of conditions includes over 900 disorders ranging from relatively prevalent disorders such as retinitis pigmentosa to very rare entities such as developmental eye anomalies. A significant number of patients with RED have an underlying genetic etiology. One of the aims of the European Reference Network for Rare Eye Diseases (ERN–EYE) is to facilitate improvement in diagnosis of RED in European member states. Main body Technological advances have allowed genetic and genomic testing for RED. The outcome of genetic testing allows better understanding of the condition and allows reproductive and therapeutic options. The increase of the number of clinical trials for RED has provided urgency for genetic testing in RED. A survey of countries participating in ERN-EYE demonstrated that the majority are able to access some forms of genomic testing. However, there is significant variability, particularly regarding testing as part of clinical service. Some countries have a well-delineated rare disease pathway and have a national plan for rare diseases combined or not with a national plan for genomics in medicine. In other countries, there is a well-established organization of genetic centres that offer reimbursed genomic testing of RED and other rare diseases. Clinicians often rely upon research-funded laboratories or private companies. Notably, some member states rely on cross-border testing by way of an academic research project. Consequently, many clinicians are either unable to access testing or are confronted with long turnaround times. Overall, while the cost of sequencing has dropped, the cumulative cost of a genomic testing service for populations remains considerable. Importantly, the majority of countries reported healthcare budgets that limit testing. Short conclusion Despite technological advances, critical gaps in genomic testing remain in Europe, especially in smaller countries where no formal genomic testing pathways exist. Even within larger countries, the existing arrangements are insufficient to meet the demand and to ensure access. ERN-EYE promotes access to genetic testing in RED and emphasizes the clinical need and relevance of genetic testing in RED.

scholarly journals Whole-Body Regeneration in Sponges: Diversity, Fine Mechanisms, and Future Prospects

Genes ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 506
Author(s):  
Alexander Ereskovsky ◽  
Ilya E. Borisenko ◽  
Fyodor V. Bolshakov ◽  
Andrey I. Lavrov
Keyword(s):  
Single Species ◽  
Whole Body ◽  
Phylogenetic Position ◽  
Main Body ◽  
Regenerative Processes ◽  
Cellular Mechanisms ◽  
Different Types ◽  
Dissociated Cells ◽  
Shed Light ◽  
Regeneration Processes

While virtually all animals show certain abilities for regeneration after an injury, these abilities vary greatly among metazoans. Porifera (Sponges) is basal metazoans characterized by a wide variety of different regenerative processes, including whole-body regeneration (WBR). Considering phylogenetic position and unique body organization, sponges are highly promising models, as they can shed light on the origin and early evolution of regeneration in general and WBR in particular. The present review summarizes available data on the morphogenetic and cellular mechanisms accompanying different types of WBR in sponges. Sponges show a high diversity of WBR, which principally could be divided into (1) WBR from a body fragment and (2) WBR by aggregation of dissociated cells. Sponges belonging to different phylogenetic clades and even to different species and/or differing in the anatomical structure undergo different morphogeneses after similar operations. A common characteristic feature of WBR in sponges is the instability of the main body axis: a change of the organism polarity is described during all types of WBR. The cellular mechanisms of WBR are different across sponge classes, while cell dedifferentiations and transdifferentiations are involved in regeneration processes in all sponges. Data considering molecular regulation of WBR in sponges are extremely scarce. However, the possibility to achieve various types of WBR ensured by common morphogenetic and cellular basis in a single species makes sponges highly accessible for future comprehensive physiological, biochemical, and molecular studies of regeneration processes.

scholarly journals Traditional uses, phytochemistry, pharmacology and toxicity of Arisaema (Areaceae): a review

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Heena Ali ◽  
Ubaid Yaqoob
Keyword(s):  
Skin Irritation ◽  
Clinical Applications ◽  
Human Populations ◽  
Main Body ◽  
Anticancer Activities ◽  
Medicinal Uses ◽  
The World ◽  
Different Types ◽  
Tropical Areas ◽  
Medicinal Properties

Abstract Background The genus Arisaema (Areaceae), popularly known as cobra lilies and jack in pulpit is mainly found in temperate to tropical areas of all continents except South America, Europe and Australia and contain about more than 250 species. Arisaema genus is being used by the different folks of human populations for medicinal as well as food purposes. Arisaema plants are used for the treatment of different types of diseases. There have been several attempts to highlight different aspects of genus Arisaema by describing it in terms of phytochemistry and medicinal uses. The present study is, however, an attempt to put together all the former data available related to the phytochemistry and medicinal uses of genus Arisaema. Main body The phytochemicals of the plant include alkaloids, phenols, terpenes, flavonoids, lectins, saponins, glycosides, triterpenoids, stigmasterols, n-alkanes, n-alkanols sitosterols, campesterol, oxalates, coumarins, tannins etc. Moreover, the properties such as antioxidant, antifungal, antibacterial, insecticidal, antimicrobial, cytotoxic, nematocidal, antiallergic antitumour and anticancer activities are also shown by the plants belonging to genus Arisaema. Arisaema plants have been traditionally used to treat various ailments such as resolving phlegm, dampness, and to treat asthma, bronchitis, cold, cough, and laryngitis etc. It has been found that there are several species which are toxic by nature. The development of clinical applications of arisaematis rhizomes had been seriously constrained due to its toxic properties like, mouth and lingua pain, even respiration slowing and suffocation, mucous membrane and skin irritation etc. and this toxicity of arisaematis rhizomes is due to raphide components. Conclusions The collection of data available on the phytochemistry of genus Arisaema is not sufficient as further work is required to do on phytochemical and medicinal basis. The data available on phytochemistry and medicinal properties of the plants belonging to genus Arisaema throws light on various species of Arisaema which are medicinally important and have been exploited to treat different types of diseases in the world.

scholarly journals (P2-6) Evaluation of Air Rescue Missions Using a Helicopter — Analysis from a German Helicopter Base

2011 ◽  
Vol 26 (S1) ◽  
pp. s137-s137
Author(s):  
M.D. Frank ◽  
U. Aschenbrenner ◽  
G. Nitschke ◽  
J. Braun
Keyword(s):  
Injury Severity ◽  
Air Rescue ◽  
Coronary Syndrome ◽  
Central Computer ◽  
Emergency Medical ◽  
Thoracic Drainage ◽  
Number Of Patients ◽  
Naca Score ◽  
Rescue System ◽  
Surrounding Areas

IntroductionIn Germany, emergency medical care is provided by ambulances. Emergency physicians also are used in the German rescue system to ensure primary care. Additionally, rescue helicopters are insertable. The rescue helicopter in Dresden covers the city of Dresden and its surrounding areas, with 517,000 inhabitants and distances up to 70 km. The goal of this study was to evaluate emergency cases in helicopter rescue missions according to primary diagnoses and severity of the mission on the basis of NACA Score.MethodsData from all emergencies using the German Air Rescue (DRF-Luftrettung) Helicopter Base Dresden were recorded on a standardized protocol and transferred to a central computer database (MEDAT®). Data from all emergency cases between January 2006 and July 2010 were analyzed.ResultsThere was a total of 6,310 emergencies during the study period, with a significant increase over time. The helicopter was on-scene within 10.9 minutes. In total, 54% of the patients were male. The rate of female patients > 80 years of age was 64.5%. A total of 63.4% of patients suffered life-threatening injuries or dysfunctions and a NACA score ≥ 4. A total of 7.6% of patients were classified in NACA 6 or 7. The most common cause for rescue missions was an acute coronary syndrome (20.4%). Other frequent diagnoses included brain injury (13.3%), unconsciousness (12.5%), stroke (12.9%), general cerebral convulsion (7.9%), polytrauma (6.4%), and cardiac arrest (5.0%). The rate of prehospital endotracheal intubation was 15.1%. In 1.1% of patients, a thoracic drainage was established.ConclusionsIn recent years the number of helicopter rescue missions increased, along with injury severity. The total number of patients with NACA 6 and 7 was extremely high, and demonstrates the need for an efficient emergency medical rescue system that includes helicopters.

Differential Diagnosis of Seborrheic Dermatitis

1986 ◽  
Vol 7 (7) ◽  
pp. 204-211
Author(s):  
Mary L. Williams
Keyword(s):  
Atopic Dermatitis ◽  
Differential Diagnosis ◽  
Metabolic Diseases ◽  
Fungal Infections ◽  
Seborrheic Dermatitis ◽  
Local Therapy ◽  
Skin Condition ◽  
Unknown Etiology ◽  
Common Skin ◽  
Nutritional And Metabolic Diseases

Seborrheic dermatitis is a common skin condition of infancy of unknown etiology. The disorder is usually mild and responsive to therapy. In severe or atypical cases, a variety of other entities should be considered in the differential diagnosis. Atopic dermatitis, psoriasis, psoriasiform-id reaction, fungal infections, and irritant contact dermatitis can be differentiated on clinical grounds. Less common but more serious disorders, such as histiocytosis X, immunodeficiency disorders, and nutritional and metabolic diseases, may be considered in the child whose disease does not spontaneously resolve or respond satisfactorily to local therapy. Laboratory studies including skin biopsy may be helfpul in these cases. Seborrheic dermatitis is uncommon in children after infancy and before puberty. In this age group, scalp scaling is likely to be due to other causes, such as tinea capitis, atopic dermatitis, or psoriasis.

scholarly journals MEDICAL MANAGEMENT OF TINEA INFECTION THROUGH SHODHANA AND SHAMANA – A CASE SERIES

2021 ◽  
Vol 9 (9) ◽  
pp. 2029-2036
Author(s):  
Asha A Bhat ◽  
Prashanth A S
Keyword(s):  
Case Series ◽  
Skin Condition ◽  
Wilcoxon Rank Sum Test ◽  
Common Skin ◽  
Skin Conditions ◽  
Almost All ◽  
Continuous Use ◽  
Present Case Study

Skin is one of the most beautiful organs God has ever blessed to anyone. Everyone craves for beautiful skin and makes all possible efforts to make it glow. To achieve this, they are engaged in continuous use of creams, moist- urizers and other cosmetic articles which lead to immediate or long-term skin issues. Itching being the predomi- nant symptom of these cosmetic issues make people highly embarrassed in society. In Ayurveda, almost all skin conditions are explained under one umbrella called Kushta. It is broadly classified into Mahakushta and Kshudra- kushta1. Dadru Kushta one among the Kshudra Kushta is the most common skin condition accounts for 20% in all consultation in general practice2. North Karnataka is well known for its hot and humid conditions making its population at risk of many Tinea infections. Kandu, Raga and Atasi Pushpa Sankashavat Mandala are the cardi- nal features of Dadru3. In the present case study, 40 patients of Dadru Kushta were taken according to inclusion criteria. The combined effect of both Shodhana and Shamana was assessed. Keywords: Dadru Kushta, Aupasargika, Anushangi, Wilcoxon Rank Sum Test

Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis (INCOMIN Trial) II: analysis of MRI responses to treatment and correlation with NAb

2006 ◽  
Vol 12 (1) ◽  
pp. 72-76 ◽  
Author(s):  
P Barbero ◽  
M Bergui ◽  
E Versino ◽  
A Ricci ◽  
J J Zhong ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Logistic Regression ◽  
Primary Outcome ◽  
Interferon Beta ◽  
Active Lesion ◽  
Number Of Patients ◽  
Different Types

Background In RRMS, clinical exacerbations are usually associated with different types of active lesions at MRI, including: hyperintense lesions on T1-weighted post-gadolinium sequences; new hyperintense lesions or enlarging old lesions on PD/T2-weighted scans; or new hypointense lesions on T1-weighted pre-Gd sequences. Objective/methods Primary outcome was the occurrence of patients with at least one active MRI lesion of the different types indicated above during treatment with 250 mg every other day (EOD) interferon beta (IFNβ)-1b or 30 mg once weekly (OW) IFNβ-1a in outpatients with RRMS (INCOMIN Trial). Results The number of patients with at least one ‘active’ lesion, evaluated over the two-year follow-up, was significantly (P=0.014) lower in the EOD IFNβ-1b arm (13/76, 17%) then in the OW IFNβ-1a arm (25/73, 34%). NAb frequency over two-year follow-up was 22/65 (33.8%) in the EOD IFNβ-1b arm and 4/62 (6.5%) in the OW IFNβ-1a arm, significantly greater in the EOD IFNβ-1b arm. Conclusions The development of MRI active lesions is strongly reduced by EOD-IFNβ-1b compared with OW-IFNβ-1a, indicating that EOD-IFNβ-1b is more effective than OW-IFNβ-1a in reducing ongoing inflammation and demyelination in MS. Logistic regression showed that NAb status did not affect the risk of MRI activity.

The treatment of paediatric burns with concentrated surfactant gel technology: a case series

2020 ◽  
Vol 29 (Sup6) ◽  
pp. S12-S17
Author(s):  
Timothy P Pittinger ◽  
Danielle Curran ◽  
Michel HE Hermans
Keyword(s):  
Antimicrobial Agent ◽  
Case Series ◽  
Retrospective Chart Review ◽  
Ease Of Use ◽  
Anatomical Location ◽  
Paediatric Patients ◽  
Number Of Patients ◽  
Paediatric Burns ◽  
Different Types ◽  
Topical Antimicrobial

Objective: To assess the safety and efficacy of a surfactant-based technology for the management of burns. Method: In a retrospective review, paediatric patients with different types of burns were treated with the gel technology. In some patients, the treatment was combined with a topical antimicrobial agent. Primary objectives of the review were the assessment of healing, healing times and ease of use of the material. Results: The wounds of 15 paediatric patients with different types of burns, particularly with regard to depth and anatomical location, were evaluated using a retrospective chart review. It was found that the surfactant gel technology, with or without the topical antimicrobial agent, assisted in autolytic debridement, and that time to re-epithelialisation was short and within the range of those obtained with other established treatments. Conclusion: The number of patients and wounds in this evaluation is small but the study indicates that the gel technology provides a safe and effective way to treat smaller burns in paediatric patients.

Acne in aesthetics: a common skin condition and the practitioner's role in helping

2019 ◽  
Vol 8 (9) ◽  
pp. 430-433 ◽  
Author(s):  
Kev Hubbard
Keyword(s):  
Skin Condition ◽  
Treatment Modalities ◽  
General Overview ◽  
Aesthetic Practice ◽  
Common Skin ◽  
The Common ◽  
Common Problems

This article will provide a general overview of the pathophysiology of acne presentations that may be seen in aesthetic practice, as well as common problems associated with acne. Some of the common treatment modalities that can be used in aesthetic practice will then be discussed. By doing this, the author hopes that aesthetic practitioners will be more confident and more able to manage clients with this potentially debilitating condition.

Sign in / Sign up

Export Citation Format

Share Document