scholarly journals The impact of rTMS on patients with dual diagnosis of depressive disorder and substance use disorders

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S250-S250
Author(s):  
Wael Foad ◽  
Rami Alhawi ◽  
Samer Altamimi ◽  
Zahid Hussain ◽  
Hamdy Moselhy ◽  
...  
Keyword(s):  
Substance Use ◽  
Depressive Disorder ◽  
Relapse Rate ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Average Score ◽  
Drug Screen ◽  
Safe Treatment ◽  
Number Of Patients ◽  
The Impact

AimsWe aim to investigate the effectiveness of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing consumption and craving among patients with Substance Use Disorder (SUD) and comorbid depressive disorder.BackgroundDorsolateral prefrontal cortex (DLPFC) is greatly involved in SUD evolution (1). Research has turned to targeting this brain area with rTMS; a non-invasive brain stimulation technique that modulates cortical excitability by sending pulsatile electromagnetic fields through the skull and into the brain (2). rTMS is an FDA approved and safe treatment option for treatment-resistant depression (TRD) (3).MethodFifty-four patients were admitted over six-month period of time (June 2019- December 2019) to the inpatient unit of Erada center for treatment and rehabilitation of SUD in Dubai. All patients who fulfilled ICD-10 diagnoses of Depressive disorder and SUD were screened for further assessment.Positive drug screen was confirmed through urine analysis. Hospital Anxiety and Depression Scale (HADS) and Brief Substance Craving Scale (BSCS) were applied to all participants. Patients were contracted for 5-times weekly High frequency (10 Hz) rTMS for 4 weeks (total of 20 treatments). Those who managed to complete their contracted TMS sessions were matched for age and sex with similar number of patients who received standard treatment as usual (TAU). Stimulation was as per FDA clearance for rTMS application in TRD.ResultEight patients were excluded (previous head trauma). A total of 46 patients had TMS mapping; nine of whom completed 20 sessions.Opioids was the most commonly used drug in almost 52% of patients (n = 14), followed by amphetamines in almost 30% (n = 8) and Cannabis in 18.5% (n = 5).Among those who completed 20 rTMS sessions; HADS scores on anxiety and depression fell by 85% and 78% respectively. BSCS score fell by 98%. Relapse rate (defined by positive drug screen) at 3 months was 33%.For those who completed 10 sessions; there was only 50% reduction on BSCS scores and 66% relapse rate. There were no data available on their HADS scores (only collected at baseline and at completion of 20 sessions).Those who only had TAU; there were no reduction in their BSCS (average score of 7 at both baseline and after 2 weeks).ConclusionOur findings suggest that rTMS may be an effective and safe treatment for both depressive disorder and craving for SUD which is supported by other studies (3,4).Our study is probably the first of its kind within Middle East population with addiction problems.

scholarly journals Anxiety and depression intensity and the quality of life of patients with an implanted pacemaker

2021 ◽  
Vol 11 (6) ◽  
pp. 170-177
Author(s):  
Kamil Sikora ◽  
Robert Jan Łuczyk ◽  
Agnieszka Wawryniuk ◽  
Marta Łuczyk ◽  
Agnieszka Zwolak
Keyword(s):  
Quality Of Life ◽  
Standard Deviation ◽  
Pacemaker Implantation ◽  
Depression Scale ◽  
Anxiety Scale ◽  
Anxiety And Depression ◽  
Average Score ◽  
The Impact ◽  
Implanted Pacemaker

Introduction. The consequences of anxiety and depression in various forms affect the course of cardiovascular diseases - including patients with an implanted pacemaker. To improve the quality of care for such patients, it is important to understand the scale of the problem, as well as to determine the impact of the above-mentioned symptoms on the patients' quality of life.Aim of research. The aim of the study was to assess the relationship between the quality of life and the anxiety and depression intensity on patients with implanted pacemakers.Material and methods. The study involved 100 patients hospitalized at the SPSK 4 cardiology clinic in Lublin with an implanted pacemaker. The method of diagnostic survey and research tools were used - the WHOQOL - Bref questionnaire to assess the quality of life and the Hospital Anxiety and Depression Scale (HADS-M). The results of the research are summarized in the statistical analysis.Results. The average score obtained by the respondents on the depression scale was 6.05 points with a standard deviation of 4.47. On the anxiety scale, this result was 7.99 points with a standard deviation of 4.54. The results indicating disorders in both scales concern values higher than or equal to 11 points. On the depression scale they were obtained by 16% of the respondents, while on the anxiety scale 26%. The conducted analyses showed a statistically significant relationship between the level of anxiety and depression and the quality of life of the respondents in all domains. The overall declared quality of life of the respondents and the self-esteem of the health condition were the lower, the higher the anxiety and depression severity coefficient in the study group.Conclusions.1. Most of the studied patients with pacemakers do not have high levels of anxiety and depression. 2. The occurrence of anxiety and depression affects the quality of life of respondents after pacemaker implantation in all domains. 3. Patients with high levels of anxiety and depression have a lower assessment of their quality of life and health.

Changes in anxiety and depression symptoms associated to the outcome of MOH: A post-hoc analysis of the Comoestas Project

Cephalalgia ◽  
2017 ◽  
Vol 38 (4) ◽  
pp. 646-654 ◽  
Author(s):  
Sara Bottiroli ◽  
Marta Allena ◽  
Grazia Sances ◽  
Roberto De Icco ◽  
Micol Avenali ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Affective State ◽  
Antidepressant Drugs ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression Symptoms ◽  
Depression And Anxiety ◽  
Symptoms Of Depression ◽  
Number Of Patients ◽  
The Impact

Aims To evaluate the impact of treatment success on depression and anxiety symptoms in medication-overuse headache (MOH) and whether depression and anxiety can be predictors of treatment outcome. Methods All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion over a six-month period. Depression and anxiety were assessed using the Hospital Anxiety and Depression Scale. Results A total of 663 MOH patients were evaluated, and 492 completed the entire protocol. Of these, 287 ceased overuse and reverted to an episodic pattern (responders) and 23 relapsed into overuse. At the final evaluation, the number of patients with depressive symptoms was reduced by 63.2% among responders ( p < 0.001) and did not change in relapsers ( p = 0.13). Anxious symptomatology was reduced by 43.1% in responders ( ps < 0.001) and did not change in relapsers ( p = 0.69). At the multivariate analysis, intake of a prophylactic drug and absence of symptoms of depression at six months emerged as prognostic factors for being a responder (OR 2.406; p = 0.002 and OR 1.989; p = 0.019 respectively), while lack of antidepressant drugs and presence of symptoms of depression at six months were prognostic factors for relapse into overuse (OR 3.745; p = 0.004 and OR 3.439; p = 0.031 respectively). Conclusions Symptomatology referred to affective state and anxiety can be significantly reduced by the treatment of MOH. Baseline levels of depression and anxiety do not generally predict the outcome at six months. Their persistence may represent a trait of patients with a negative outcome, rather than the consequence of a treatment failure.

scholarly journals AB0926-PARE IMPACT OF COVID 19 PANDEMIC ON TUNISIAN SPA PATIENTS: PSYCHOLOGICAL STATE AND TREATMENT ADHERENCE

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1484.2-1484
Author(s):  
M. Rachdi ◽  
A. Feki ◽  
Z. Gassara ◽  
S. Ben Jemaa ◽  
M. Ghali ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Treatment Adherence ◽  
Depression Scale ◽  
Psychological State ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Medical Support ◽  
Number Of Patients ◽  
To Come ◽  
The Impact

Background:The challenge posed by the COVID-19 pandemic may represent an overwhelmingly stressful event for ankylosing spondylitis (SpA) patients and impact their treatment adherence. In response to the COVID-19 pandemic, Tunisia,have adopted community containment to manage the spread of the virus. However, COVID-19 restrictions can alter psychological wellbeing and limit access to treatment for SpA patients.Objectives:This study aimed to evaluate the impact of COVID-19 pandemic on psychological health and treatment adherence on Tunisian SpA patients.Methods:This is a cross sectional study including patients with SpA (ASAS criteria). A survey comprising questions about adherence to stay home warnings; the obligation to go outside for work; satisfaction with the medical support or information received for COVID-19; showing up to medical check-ups, proper use of the medications; medications that the patient stopped taking.Anxious and depressive symptoms were assessed using the Arabic version of Hospital Anxiety and Depression Scale (HADS) questionnaire.Results:We included thirty patients. the average age was: 39,7 years-old and the sex ratio was: 13,3. 75 % of patients were married. The SpA was axial in 25%, peripheral in 20%, and both in 55 %. Most patients had a moderate activity and the mean activity scores were: BASDAI = 2.60, ASDAScrp:2.6538% of patients were on biologics, 36 % on sulfasalazine and NSAIDs and 26 % on NSAIDs only.It seemed that significant number of patients strictly adhered to stay home warnings (> 89%) only 11% were obliged to go out for work during general lockdown while only 24 % adhered to it after general lockdown.Most of the patient 78 % were not satisfied with the medical support or information about COVID 19. 88% of patients requested information from TV while 10 % requested it from social media and 2 % from relatives and friends working in health care field.After the outbreak, 23% of the patients who had a scheduled chek-up visit attended the appointment as it was before.The remaining either ‘did not want to come’ (43%), wanted to come but could not contact anyone in the hospital (11%), was advised to postpone their visits (10%), or couldn’t find means of transport (13%).A significant number of patients decreased or skipped their dose (69%), while only 13% continued their medications and 16%stopped taking NSAIDs.Biological DMARDs(anti-TNF agents) were the most frequent drugs which patients decreased their dose, skipped or stopped taking 33%. sulfasalazine and NSAIDs were least likely 17% to be skipped or stopped.43% of patients Had a HADS anxiety level more than or equal to 11: 87 % women and 13 % men. The highest anxiety scores were found among patients aged less than 45 years old (87%) married with children .32% of patients had a HADS depression level more than or equal to 11: 54 % women and 44 % men. the highest depression scores were found among patients aged less than 45 years old married with children.No significant relationship was found between anxiety and depression levels regarding biologic treatment.Conclusion:Our results suggest that patients with SpA were less likely to comply strictly to ‘stay home’ restrictions, most probably due to the male predominance and relatively younger age. Additionally, we noticed that SpA patients treated with anti-TNF agents were the patients that regular drug use had been considerably disrupted.COVID 19 pandemic has heightened the need to care for patients with SpA in an increasingly virtual environment.Additionally, we found that being female, having a lower level of education, having a child, living in a crowded family is correlated to higher levels of anxiety and depression.References:[1]Smarr KL, Keefer AL. Measures of depression and depressive symptoms: Beck Depression Inventory-II (BDI-II),Hospital Anxiety and Depression Scale (HADS), and Patient Health Questionnaire-9 (PHQ-9) Arthritis care.Acknowledgements:I would like to express my special thanks of gratitude to Rheumatology department of Hedi Chaker Hospital Sfax.Disclosure of Interests:None declared

scholarly journals Family Physicians’ Standpoint and Mental Health Assessment in the Light of COVID-19 Pandemic—A Nationwide Survey Study

2021 ◽  
Vol 18 (4) ◽  
pp. 2093
Author(s):  
Tina Vilovic ◽  
Josko Bozic ◽  
Marino Vilovic ◽  
Doris Rusic ◽  
Sanja Zuzic Furlan ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Care ◽  
Perceived Stress ◽  
Depression Scale ◽  
Family Physicians ◽  
Knowledge Score ◽  
Well Being ◽  
Anxiety And Depression ◽  
Event Scale ◽  
The Impact

During the coronavirus disease 2019 (COVID-19) outbreak, family physicians (FPs) are the backbone of the healthcare system with considerable impact on the general population, and their well-being is of great importance. The aim of this investigation was to assess FPs mental health, as well as knowledge, attitudes and practices (KAPs) regarding the pandemic, and opinions on non-communicable disease (NCD) health care provided to patients. A cross-sectional study was carried out with a sample of 613 FPs. Anxiety and depression levels were estimated with the Hospital Anxiety and Depression Scale, subjective perceived stress with the Perceived Stress Scale, while trauma-related symptoms were assessed using the Impact on Event Scale-COVID19. KAPs toward the pandemic and opinions regarding NCD patients were evaluated with questionnaires accordingly. Results have shown that age (β = −0.02, p = 0.013) and personal risk of COVID‑19 (β = 1.05, p < 0.001) were significant independent correlates of the knowledge score. A total of 87.7% FPs expressed moderate/high perceived stress, 45.2% moderate/severe trauma-related symptoms, 60.4% borderline/abnormal anxiety levels, and 52.4% borderline/abnormal depression levels. Knowledge score was an independent predictor of perceived stress (β = −0.33, p = 0.023) and anxiety (β = −0.31, p = 0.006) levels. Limited accessibility to healthcare services and decreased number of newly-diagnosed NCD cases were mostly agreed on. The pandemic puts a considerable strain on FPs mental health, as well as on public health measures, due to the decreased overall quality of NCD patient health care. Educational programs may bridge the gaps between FPs’ knowledge. Thus lowering anxiety and improving patient care.

THE IMPACT OF GENDER, ANXIETY, AND DEPRESSION ON PERFORMANCE ON PURSUIT ROTOR

2007 ◽  
Vol 35 (5) ◽  
pp. 615-626
Author(s):  
Khader Baroun
Keyword(s):  
Undergraduate Students ◽  
Depression Scale ◽  
Anxiety Scale ◽  
Anxiety And Depression ◽  
Kuwait University ◽  
Pursuit Rotor ◽  
Low Levels ◽  
High Level ◽  
The Impact ◽  
Significant Increment

In this study the impact of gender, levels of anxiety, and depression on pursuit rotor performance task was investigated. The participants were 292 undergraduate students (171 men and 121 women) of Kuwait University, Kuwait. They completed an anxiety scale, depression scale, and 4 speed levels of pursuit rotor. They were divided into 3 groups (low, middle, and high anxiety and depression) based on their scores on the Kuwait University Anxiety Scale (KUAS; Abdel-Khalek, 2000) and the Beck Depression Inventory (BDI-II; Beck, Ward, Mendelson, Mock, & Erbaugh, 1961). The results revealed that groups of men with low levels of anxiety, and high level of depression showed significant increment in performance and had more time on target than the other groups in all 4 speed sessions, whereas women displayed less time on target of pursuit rotor.

Impact of Preventive Therapy with Nadolol and Topiramate on the Quality Of Life Of Migraine Patients

Cephalalgia ◽  
2007 ◽  
Vol 27 (8) ◽  
pp. 920-928 ◽  
Author(s):  
JC Garcia-Monco ◽  
N Foncea ◽  
A Bilbao ◽  
I Ruiz de Velasco ◽  
M Gomez-Beldarrain
Keyword(s):  
Quality Of Life ◽  
Depression Scale ◽  
Preventive Therapy ◽  
Anxiety And Depression ◽  
Physical Domain ◽  
Depressive State ◽  
Migraine Frequency ◽  
Sf 36 ◽  
The Impact

Preventive therapy is aimed at reducing migraine frequency, but should also improve the much deteriorated quality of life of the migraneur. We aimed to evaluate the impact of preventive therapy with two widely employed drugs (topiramate and nadolol) on the quality of life of migraine patients. A population of consecutive migraineurs aged ≥16 years, with frequent migraines, was selected prospectively for evaluation at baseline and after 16 weeks of therapy with nadolol or topiramate (40 mg and 100 mg daily, respectively) by generic and specific quality of life questionnaires (SF-36 and MSQOL) and by an anxiety and depression scale (HADS). Preventive therapy resulted in a statistically significant improvement in physical domains of the SF-36, whereas mental domains remained almost unchanged. Despite this improvement, all domains remained below the population norms. The HADS revealed a moderate depressive state at baseline that did not change with therapy. The MSQOL global score also revealed statistically significant improvement. Both drugs were similarly effective, although topiramate was superior on the role physical domain compared with nadolol. Preventive therapy with nadolol and topiramate significantly improves the quality of life of migraineurs, although additional efforts are needed to place them in a nearer-to-normal situation compared with the general population.

EVALUATION OF ANXIETY AND DEPRESSION DISORDERS AND THE ASSOCIATED FACTORS AMONG HEMODIALYSIS SUBJECTS

2019 ◽  
Vol 17 (4) ◽  
pp. 405-416
Author(s):  
Driss Touil ◽  
Mahjoub Aouane ◽  
Ahmed Omar Touhami Ahami
Keyword(s):  
Analytical Study ◽  
Depressive Disorders ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Psychiatric Evaluation ◽  
Average Score ◽  
Dialysis Unit ◽  
Taking Charge ◽  
Depression Disorders ◽  
Anxious State

Identifying anxio-depressive disorders, evaluating their prevalence and determining the different factors that can intervene in their hap- pening to the patients suffering from hemodialysis. Transversal descriptive and analytical study over 70 patients, real- ized at the dialysis unit of the Idrissi regional hospital’s department of medicine at Kenitra, Morocco, over a period of three months starting from 27 March to 26 June 2015. The data were acquired from a survey and psychiatric evaluation scales: The scale HADS (Hospital Anxiety and Depression Scale ) to evaluate anxiety and depression and the scale of « Big Five French Inventory to evaluate the treats of personality» (BF-Fr). Average age was from 54,66±15,96 years. The seniority of the hemodialysis was on average 5,20±3,23 years. The studied traits of personality show a decrease regard to the average score of dimen- sion O (overture of sense) and of the dimension E score (extraversion) versus an evaluation of the dimension N score (Neu ro ticism). The prevalence of anxio-depressive troubles were as the following; 74,29% presented an anxious state (suspected or proven) and 70% had a depressive state (suspected or proven). The anxious troubles were correlated to age and to N and O characters of personality traits BFI-Fr. the depressive troubles were correlated to N charac- ters traits of personality BFI-Fr, and the anxious troubles were pos- itively correlated to depressive troubles. The prevalence of anxio-depressive troubles among hemodialysis subjects was elevated with repercussions on the personality. The involvement of a psychologist in the processes of taking charge is obligatory.

Psychophysical functioning and quality of life in 94 patients affected by oropharyngeal cancer and treated with different therapeutic approaches.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 6039-6039
Author(s):  
Fulvia Pedani ◽  
Mario Airoldi ◽  
Massimiliano Garzaro ◽  
Riccardo Torta ◽  
Luca Raimondo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Functioning ◽  
Depression Scale ◽  
Stage Iv ◽  
Stage Iii ◽  
Lower Percentage ◽  
Anxiety And Depression ◽  
Anxiety Depression ◽  
The Impact

6039 Background: The treatment of oropharyngeal squamous cell carcinomas (OSCC) may heavily affect patient’s quality of life (QoL). Aim of our study was the evaluation of the impact of different treatments on physical and psychological functioning and on QoL of patients affected by stage III-IV disease. Methods: The enrolled sample was composed by 94 OSCC patients divided into 3 subgroups based on treatment modalities: surgery + adjuvant radiotherapy (S + RT: 30 patients), exclusive concomitant chemo-radiotherapy (CT + RT: 30 patients) and exclusive chemotherapy (CT) in 34 patients not suitable for surgery and/or radiotherapy. Psycho-oncological assessment included: Hospital Anxiety Depression Scale (HADS), Montgomery-Asberg Depression Scale (MADRS), Mini-Mental Adjustment to Cancer scale (MINI-MAC), EORTC QLQ C-30 questionnaire with the specific module Head and Neck 35 (H&N35). Results: The 60 patients primarily treated with S + RT or CT + RT presented superimposeable clinical and tumour characteristics while those treated with exclusive CT were affected by stage IV disease and in the 90% of cases underwent to previous treatment exclusive or combined treatment such as surgery, radiotherapy and chemotherapy. In the following table, data about physical and psychological functioning and on QoL of the 3 subgroups of patients are summarized. Conclusions: In stage III-IV OSCC treatments have a strong influence on QoL and coping styles. Patients treated with CT + RT were characterized by a lower percentage of self-reported anxiety and depression and higher EORTC Global QoL score. More than one third of patients treated with S + RT had overt symptoms of anxiety and depression. Stage IV patients treated with palliative CT had elevated level of anxiety, depression and low quality of life. Auto-evaluation is less effective in depression assessment. The role of concomitant psychological supportive care should be evaluated in these patients treated with different approaches. [Table: see text]

Partners of young breast cancer survivors: A cross-sectional evaluation of psychosocial issues and mental health.

2017 ◽  
Vol 35 (5_suppl) ◽  
pp. 184-184 ◽  
Author(s):  
Nancy Borstelmann ◽  
Shoshana M. Rosenberg ◽  
Shari I. Gelber ◽  
Meghan E Meyer ◽  
Kathryn Jean Ruddy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mental Health ◽  
Social Support ◽  
Coping Strategies ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Full Time ◽  
Maladaptive Coping ◽  
Psychosocial Concerns ◽  
The Impact

184 Background: While evidence of the challenges of cancer caregiving has been growing, scant research addresses the experience of partners of young adults with cancer. These individuals and their relationships may be particularly vulnerable to stress, especially when managing the complexity of cancer care and survivorship with their partner. We sought to evaluate psychosocial concerns and mental health in the partners of young survivors of early stage breast cancer (BC). Methods: We invited partners of young women w/BC diagnosed at age ≤ 40 yrs enrolled in a prospective cohort study to participate in a one-time survey evaluating psychosocial concerns including quality of life, coping, social support, financial insecurity, partnership concerns, parenting concerns, anxiety and depression. Logistic regression was used to explore predictors of anxiety (score > 8 on Hospital Anxiety and Depression Scale (HADS)). Results: Most respondents (284/289) were male, with median age 43 yrs (range 27-65). The median time of survey completion was 62 months (range 16 -114) after their partner’s dx. Respondents were mostly white (93%), working full time (94%), and college educated (78%); 29% reported some financial stress, 74% were parenting children < 18 yrs, and 32% reported at least a fair amount of relationship concern. 42% (106/250) had anxiety (39/289 respondents (13%) had incomplete/missing HADS). In univariable analyses, lower education, working full time, parenting concerns, insufficient social support and maladaptive coping were associated (p < .05) with anxiety. In the multivariable model, only maladaptive coping remained significantly associated with anxiety (p < .01, OR = 2.32 (95% CI: 1.22, 4.39)). Conclusions: Partners of young BC survivors who used less constructive/more maladaptive coping strategies experience negative mental health outcomes after tx has ended. Caregivers’ anxiety may have implications for both their own and survivors’ health and QOL. Future interventions might focus on the development of constructive coping strategies to enhance adjustment and role effectiveness in dealing with the impact of cancer.

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