Vitamin C in Senile Psychoses

1940 ◽  
Vol 86 (363) ◽  
pp. 675-679 ◽  
Author(s):  
P. Berkenau
Keyword(s):  
Old Age ◽  
Unsolved Problem ◽  
Clinical Symptoms ◽  
Senile Dementia ◽  
Brain Cells ◽  
Old People ◽  
Histological Changes ◽  
Mental Diseases ◽  
Constitutional Factor ◽  
The Brain

The senile psychoses are in regard to their origin an unsolved problem. Much valid work has been done in the field of anatomy and histology in approaching this problem, but as the mental diseases of old age cannot be separated from the growing old of body and mind generally, this problem is more or less a biological one. The borderline between old age and senile dementia is not a sharp one. In brains of old people without clinical symptoms of dementia there have been found histological changes, such as are usually found in cases of senile dementia. This makes it probable that the extent of degeneration of brain cells alone is not decisive for the appearance of senile psychoses. The finding of the characteristic plaques in the brain of senile psychoses may give evidence of the extent of the process and the severity of clinical symptoms, but it does not tell us anything about their nature and origin. Whether a constitutional factor is decisive or whether the histological changes are a reaction to an unknown noxa is undecided. Heredity may have its share too.

Comunicare con il vecchio in difficoltŕ

IKON ◽  
2009 ◽  
pp. 111-149
Author(s):  
Carlo Cristini ◽  
Marcello Cesa-Bianchi
Keyword(s):  
Old Age ◽  
Health Workers ◽  
Clinical Symptoms ◽  
Living Organism ◽  
Old People ◽  
Behavioral Disturbances ◽  
Clinical Pain ◽  
Males And Females ◽  
Old Age Depression ◽  
The Relationship

- Increase aged produces more specific dangers about health and autonomy for many old people; it is possibile to see in aged a life dicotomy: from one side autonomies, creatives, enterprising, propositives old people, from other side old people present loose of physical and mental autonomy. There are many factors that may cause with years disabilities conditions: from changes of living organism in males and females climacteric, from loneliness to alienation, from illness to institutionalized. In old age happen traumatic events, more than other phases of life, as situations about (affective, social, professional and healthy loses) that may produce clinical pain, an affecctive and cognitive decline. In old age depression and dementia represent the more frequent mental and behavioral disturbances. Of course becomes more important to learn, to analyse knolewdge and communication, suffering aged and wih his family. The relationship especially with dement, requires attention, sensitiveness, the decodification of messages, of his identity and of social relationship. Some health workers mind always to some meanings in communication that are to be analysed especially in suffering aged, with dement. Communication and understanding of old people mean give opportunities of support, of changing, of relieving painful and of its clinical symptoms.

scholarly journals Infection of sheep and monkeys with Langat virus: cross-protection against other viruses of the Russian spring-summer complex

1965 ◽  
Vol 63 (2) ◽  
pp. 213-221 ◽  
Author(s):  
K. J. O'Reilly ◽  
C. E. Gordon Smith ◽  
Dolores A. McMahon ◽  
A. L. Wilson ◽  
J. M. Robertson
Keyword(s):  
Field Trial ◽  
Clinical Symptoms ◽  
Neutralizing Antibody ◽  
Histological Changes ◽  
Central European ◽  
Forest Disease ◽  
Tick Borne Encephalitis ◽  
Langat Virus ◽  
Louping Ill ◽  
The Brain

1. The susceptibility of sheep to infection with Langat virus has been studied. No viraemia or symptoms were detected in sheep inoculated either subcutaneously or intracerebrally.2. Only those sheep inoculated intracerebrally with 106·0–108·0 mouse IC LD 50 of virus developed significant quantities of neutralizing antibody.3. Two-thirds of sheep vaccinated with varying doses of Langat virus withstood subcutaneous challenge of louping-ill virus followed by intracerebral starch. All the intracerebrally vaccinated sheep survived this form of challenge but no sheep, whether vaccinated subcutaneously or intracerebrally, withstood intracerebral challenge of louping ill.4. In a field trial, three of ten hoggs vaccinated with Langat virus and exposed to natural louping ill infection at Camlarg and Dalcairnie died of the disease compared with all eight of the non-vaccinated hoggs. At Knockgray, there was no louping ill infection, but 93% of the hoggs from this hirsel developed louping ill antibody after transfer to Camlarg.5. Monkeys infected intracerebrally, subcutaneously or orally with Langat virus showed a low titre viraemia without clinical symptoms or histological changes in the brain and developed high titres of antibody. Vaccinated monkeys challenged with either Central European tick-borne encephalitis or Kyasanur Forest disease viruses remained healthy compared with control monkeys which showed evidence of disease.

scholarly journals Memoirs: Determination of Age in Honey-Bees

1920 ◽  
Vol s2-64 (254) ◽  
pp. 191-205
Author(s):  
HELEN L. M. PIXELL-GOODRICH
Keyword(s):  
Old Age ◽  
Honey Bees ◽  
Brain Cells ◽  
Gradual Reduction ◽  
The Brain

For the study of those bee diseases with which no specific organisms have so far been identified, it is important to be able to eliminate bees dying of old age, and this cannot be done with certainty by observing outward symptoms. However, the age of bees, which normally work almost incessantly for about six weeks and then die, may be determined with some accuracy from a study of the brain-cells. With advancing age the cytoplasm of these cells undergoes gradual reduction peripherally, until in senescence only a vestige is left surrounding the nucleus. The condition of the head-glands, including a pair of œsophageal glands which do not appear to have been previously recorded, gives some indication of age in normal healthy bees.

Depression in old age

2011 ◽  
Vol 26 (S2) ◽  
pp. 702-702
Author(s):  
B. Vukovic ◽  
D. Markovic-Zigic
Keyword(s):  
Old Age ◽  
Elderly Population ◽  
Severe Depression ◽  
The Elderly ◽  
Chronic Illnesses ◽  
Age Group ◽  
Old People ◽  
Population Prevalence ◽  
Prevalence Of Depression ◽  
Mental Diseases

Depression in older people is related to the population over 65 years. The age of depression often go with chronic illnesses, various physical and mental diseases.Depression in old age is not a natural part. In the elderly population 1.4% suffered from severe depression. Compared with the rest of the population prevalence of major depression is twice as large in the age group of 70–85 years. Less severe depression have an instance 4–13%. Twice as many women than men have depression. The prevalence of depression is particularly high in the elderly with dementia.In this report we present how many old people in Serbia suffer of depression and what is new tendence in therapy.

scholarly journals Islamic Legal and regulatory provisions for Alzheimer's patients: الأحكام الشرعية والنظامية لمرضى الزهايمر

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Asma Mohammed Al-Turki
Keyword(s):  
Alzheimer’S Disease ◽  
Mental Disorders ◽  
Blood Vessels ◽  
Old Age ◽  
Brain Atrophy ◽  
Head Injuries ◽  
Brain Cells ◽  
Legal Provisions ◽  
The Brain ◽  
Work And Life

Alzheimer's is the disease of the era destroys the brain cells then affects the work and life of the patient and deteriorates gradually may lead to death after that, I liked to look for its meaning and terminology and symptoms and what the Islamic legal and legal provisions for patients, I followed in my research deductive approach, Research that Alzheimer's disease is devastating nerve causes the brain atrophy gradually and the destruction of the person's ability to learn, it has been called a number of terms of the scientists, including real dementia and cerebral dementia and mental disorders, the causes of the disease include old age and diseases of blood vessels and head injuries and has a number of types of treatments and It's also relates some of the Islamic rulings The Alzheimer's patient in the first stage applies to him the provisions of the Full-fledged person, but in the case of medium and late it passes a mixture of the provisions of madness and the ship and dementia in accordance with its provisions.    

Ageing and Senility: A Major Problem of Psychiatry

1946 ◽  
Vol 92 (386) ◽  
pp. 150-170 ◽  
Author(s):  
Aubrey Lewis
Keyword(s):  
Social Responsibility ◽  
Old Age ◽  
Senile Dementia ◽  
High Standard ◽  
The Other ◽  
Reproduction Rate ◽  
Old People ◽  
The Social ◽  
Net Reproduction

The psychiatric aspects of ageing are a major problem in any country which, like our own, has a low net reproduction rate and a high standard of social responsibility: the proportion of old people in the community steadily increases, so that they provide an increasingly high proportion of our mentally infirm population who must be cared for. But it is not only senile dementia and the other senile and presenile psychoses described in textbooks that make up the problem: less conspicuous failings which may accompany old age also call for attention if the social and preventive sides of our work are to be given due weight. Therefore it is psychiatric aspects of ageing rather than senile psychoses alone that are intended by the title of this paper.

scholarly journals The volume of changes in the cerebral cortex in senile dementia

2020 ◽  
Vol VIII (3) ◽  
pp. 156-187
Author(s):  
A. F. Lazursky
Keyword(s):  
Cerebral Cortex ◽  
Old Age ◽  
Senile Dementia ◽  
Anatomical Changes ◽  
The Subject ◽  
The Brain

The question of pathological - anatomical changes in the brain in old age and senile dementia has repeatedly served as the subject of numerous and sometimes very detailed studies.

Presence of antibody in virus-infected brain cells of SSPE ferrets

1983 ◽  
Vol 41 ◽  
pp. 804-805
Author(s):  
Hannah R. Brown ◽  
Tammy L. Donato ◽  
Halldor Thormar
Keyword(s):  
Measles Virus ◽  
Plasma Cells ◽  
Subacute Sclerosing Panencephalitis ◽  
Protein A ◽  
Neutralizing Antibody ◽  
Brain Cells ◽  
Antibody Titers ◽  
A Cell ◽  
The Central Nervous System ◽  
The Brain

Measles virus specific immunoglobulin G (IgG) has been found in the brains of patients with subacute sclerosing panencephalitis (SSPE), a slowly progressing disease of the central nervous system (CNS) in children. IgG/albumin ratios indicate that the antibodies are synthesized within the CNS. Using the ferret as an animal model to study the disease, we have been attempting to localize the Ig's in the brains of animals inoculated with a cell associated strain of SSPE. In an earlier report, preliminary results using Protein A conjugated to horseradish peroxidase (PrAPx) (Dynatech Diagnostics Inc., South Windham, ME.) to detect antibodies revealed the presence of immunoglobulin mainly in antibody-producing plasma cells in inflammatory lesions and not in infected brain cells.In the present experiment we studied the brain of an SSPE ferret with neutralizing antibody titers of 1:1024 in serum and 1:512 in CSF at time of sacrifice 7 months after i.c. inoculation with SSPE measles virus-infected cells. The animal was perfused with saline and portions of the brain and spinal cord were immersed in periodate-lysine-paraformaldehyde (P-L-P) fixative. The ferret was not perfused with fixative because parts of the brain were used for virus isolation.

SPECIFIC PROPERTIES OF TUBULIN IN THE PREFRONTAL CORTEX IN CONTROL, SCHIZOPHRENIA AND VASCULAR DEMENTIA

2020 ◽  
pp. 65-71
Author(s):  
Burbaeva G.Sh. ◽  
Androsova L.V. ◽  
Vorobyeva E.A. ◽  
Savushkina O.K.
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Prefrontal Cortex ◽  
Vascular Dementia ◽  
Binding Activity ◽  
Nephelometric Method ◽  
Rate Of Polymerization ◽  
Mental Diseases ◽  
And Control ◽  
The Brain

The aim of the study was to evaluate the rate of polymerization of tubulin into microtubules and determine the level of colchicine binding (colchicine-binding activity of tubulin) in the prefrontal cortex in schizophrenia, vascular dementia (VD) and control. Colchicine-binding activity of tubulin was determined by Sherlinе in tubulin-enriched extracts of proteins from the samples. Measurement of light scattering during the polymerization of the tubulin was carried out using the nephelometric method at a wavelength of 450-550 nm. There was a significant decrease in colchicine-binding activity and the rate of tubulin polymerization in the prefrontal cortex in both diseases, and in VD to a greater extent than in schizophrenia. The obtained results suggest that not only in Alzheimer's disease, but also in other mental diseases such as schizophrenia and VD, there is a decrease in the level of tubulin in the prefrontal cortex of the brain, although to a lesser extent than in Alzheimer's disease, and consequently the amount of microtubules.

scholarly journals Effect of Water and Ethanol Extracts from Hericium erinaceus Solid-State Fermented Wheat Product on the Protection and Repair of Brain Cells in Zebrafish Embryos

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3297
Author(s):  
Shun-Kuo Sun ◽  
Chun-Yi Ho ◽  
Wei-Yang Yen ◽  
Su-Der Chen
Keyword(s):  
Solid State ◽  
Brain Cell ◽  
Hot Water ◽  
Raw Material ◽  
Brain Cells ◽  
Zebrafish Embryos ◽  
Hericium Erinaceus ◽  
Water Extracts ◽  
The Brain ◽  
Wheat Product

Extracts from Hericium erinaceus can cause neural cells to produce nerve growth factor (NGF) and protect against neuron death. The objective of this study was to evaluate the effects of ethanol and hot water extracts from H. erinaceus solid-state fermented wheat product on the brain cells of zebrafish embryos in both pre-dosing protection mode and post-dosing repair mode. The results showed that 1% ethanol could effectively promote zebrafish embryo brain cell death. Both 200 ppm of ethanol and water extracts from H. erinaceus solid-state fermented wheat product protected brain cells and significantly reduced the death of brain cells caused by 1% ethanol treatment in zebrafish. Moreover, the zebrafish embryos were immersed in 1% ethanol for 4 h to cause brain cell damage and were then transferred and soaked in the 200 ppm of ethanol and water extracts from H. erinaceus solid-state fermented wheat product to restore the brain cells damaged by the 1% ethanol. However, the 200 ppm extracts from the unfermented wheat medium had no protective and repairing effects. Moreover, 200 ppm of ethanol and water extracts from H. erinaceus fruiting body had less significant protective and restorative effects on the brain cells of zebrafish embryos. Both the ethanol and hot water extracts from H. erinaceus solid-state fermented wheat product could protect and repair the brain cells of zebrafish embryos damaged by 1% ethanol. Therefore, it has great potential as a raw material for neuroprotective health product.

Sign in / Sign up

Export Citation Format

Share Document