The incidence of prostate cancer in patients under the age of 60 from an urban setting

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 14622-14622
Author(s):  
M. Shum ◽  
E. Bodofsky ◽  
Z. Skaff ◽  
M. El-Khoury ◽  
S. Kankipati ◽  
...  

14622 Background: Although the risk for developing prostate cancer increases with age, few studies have reported the incidence of prostate cancer in men younger than 60 from an urban setting. Methods: All patients diagnosed and treated for prostate cancer at The Cancer Institute of New Jersey at Cooper University Hospital in Camden County, New Jersey from January 1, 2004 to December 31, 2004 were retrospectively identified from our tumor registry. Age comparison at diagnosis was made utilizing the Cooper registry and the National Cancer Database (NCDB), 2001. Results: A total of 141 men (88 Caucasians, 37 African Americans, 14 Hispanic, and 6 unknown) with a median age of 64 years (range, 44–88 years) were diagnosed with prostate cancer in 2004. Staging revealed Stage II (118), Stage III (3), Stage IV (4), Stage unknown (16) cases. Median Gleason score was 6. 74 patients underwent radical prostatectomy, 50 had radiation, 30 received hormone therapy and 2 received chemotherapy. At diagnosis, 19.95% of the men were under 50 and 41.84% were under 60 years of age. Our dataset from these two age groups compared to NJ and US figures are noted below. Conclusions: When comparing the respective data sets from CINJ at Cooper to NJ and US utilizing the NCDB, there are striking differences with a higher incidence of prostate cancer in younger men. These incidences parallel those seen in other urban university teaching hospitals from the Healthcare Utilization Project (2005), where more patients under the age of 60 are being diagnosed with prostate cancer when compared to community centers. Subset analysis shows that our institution had a disproportionately larger number of African American men with prostate cancer which may relate to our culturally directed screening program, accounting for the higher incidence. These data support that hospital characteristics may impact age at diagnosis of prostate cancer, and further investigation is warranted. [Table: see text] No significant financial relationships to disclose.

2021 ◽  
Vol 45 ◽  
pp. 1
Author(s):  
Cédric Contaret ◽  
Raymond Cesaire ◽  
Jacqueline Deloumeaux ◽  
Rémi Neviere ◽  
Dabor Resiere ◽  
...  

Objective. To analyze, describe, and quantify the collaborations and scientific output of the two university teaching hospitals of Martinique and Guadeloupe, at the regional, national, and international level. Methods. A bibliometrics analysis was performed from the international databases Web of Science and PubMed, for the period from 1989 to 2018, inclusive (30 years). Three types of bibliometric indicators were used, namely quantitative indicators, performance indicators, and organization-specific indicators. Affiliations of the first and last authors were identified from PubMed. Results. Between 1989 and 2018, a total of 1 522 indexed articles were published with at least one author affiliated to either the University Hospital of Martinique (n = 827) or the University Hospital of Guadeloupe (n = 685). The majority of articles were in category Q1 (35.8% for Martinique and 35.2% for Guadeloupe). In Martinique, over the last 30 years, the three main research areas have been clinical neurology, ophthalmology, and surgery, together representing 28.7% of all research areas, with the highest number of articles published in the field of clinical neurology (n = 81). In the University Hospital of Guadeloupe, the area of hematology was largely represented, with 79 articles published. For both hospitals, the first and last authors of the article published were mainly from mainland France Conclusions. This quantitative analysis shows the development of medical and scientific research in Martinique and Guadeloupe over the last three decades, as well as the extent of their collaborative partnerships at the national and international levels.


2021 ◽  
Vol 3 (1) ◽  
pp. 79-84
Author(s):  
Panji Nkhoma ◽  
◽  
Patrick Loti ◽  
Musalula Sinkala ◽  
Hamakwa Mantina ◽  
...  

Anaemia is a condition in which either the number of red blood cells or their oxygen-carrying capacity is insufficient to meet physiologic needs, which vary by age, sex, altitude, smoking and pregnancy status. The global estimate of childhood anaemia indicates that 293.1 million children are anaemic, and 28.5% of these children reside in sub-Sahara Africa. Also,anaemia is a significant public health problem with a high age-standardised death rate of 11.18 per 100,000 in Zambia. We conducted a cross-sectional study involving 392 anaemic children aged one year to 14 years. The study was conducted at the Children Hospital, University Teaching Hospitals, which is a third-level referral Hospital in Lusaka, Zambia. The aim was to determine the most common type of anaemia, it’s severity, and the most affected age groups among children aged 1–14 years.Out of392 participants, 219 (56%) were female. Maximum haemoglobinrecorded was 10.9g/dl, a minimum of 2.0 g/dl, a mean of 7.8g/dl and a standard deviation of 1.86g/dl. 200 (51%) participants had severe anaemia, and 192 (49%) had moderate anaemia with none having mild anaemia. Microcytic hypochromic anaemia was the commonest (60%), followed by normochromic normocytic anaemia (26%) and the least was macrocytic anaemia in 14% of the participants. An analysis of variance showed that the difference in mean haemoglobin concentration between age groups was not significant, F (7.94) = 0.83, p > 0.57. A Chi-squared test was used to determine the relationship between anaemia types (microcytic, hypochromic) and age groups.The interaction was not significant (Chi-Square (1) = 1.28, p-value = 0.73. Microcytic hypochromic anaemia was the most prevalent and all age groups were equally affected.We recommend the country’s National Food and Nutrition Commission to revisit the Zambian National Strategy and Plan of Action for the Prevention and Control of Vitamin A Deficiency and Anaemia of1999 to 2004 and implement the measures stated in the strategic plan


Author(s):  
Mampionona Ranaivomanana ◽  
Tojo Rafaralahivoavy ◽  
Joelle Razafimahefa ◽  
Anicet M. Rakotovao ◽  
Rivo A. Rakotoarivelo ◽  
...  

Background: Gastrointestinal cancers are among the top 10 cancers and causes of cancer death worldwide. Given the absence of cancer registry in Madagascar and absence of epidemiological study of gastrointestinal cancer in the province of Fianarantsoa, our aim was to describe the epidemiological aspect of gastrointestinal cancers at the University Hospital of Tambohobe Fianarantsoa.Methods: Authors have conducted a descriptive retrospective study over a three-year period from January 1, 2015 to December 31, 2017 at the University Hospital of Tambohobe Fianarantsoa (in oncology, internal medicine and visceral surgery departments). The variables analyzed were age, gender, tumor location.Results: Authors have collected 74 cases of gastrointestinal cancers. There were 46 males 62.16% and 28 females 37.84%. The mean age was 56.30±12.10 years old. The predominant age groups were 45-55 years. Authors found colorectal cancer in 43%, followed by liver carcinoma in 19%, then pancreatic cancer 14%, esophageal cancer 13%, gastric cancer 8%, duodenum cancer 3%.Conclusions: Gastrointestinal cancers at the hospital of Tambohobe Fianarantsoa affect young people, especially the male gender with a predominance of colorectal and liver cancer.So, it is important to continue the vaccination against hepatitis viral B infection and to implement a colorectal cancer screening program.


2015 ◽  
Vol 12 (1) ◽  
pp. 32-37
Author(s):  
B Ghimire ◽  
YP Singh ◽  
S Timalsina

Background Gastric cancer is the second commonest cause of cancer related mortality worldwide. Though its incidence is more in Eastern Asia, it is increasing in the South Asian subcontinent. The diagnosis of early gastric cancer (EGC) confined to the mucosa or submucosa, is an important concern due to a better outcome at this stage where five year survival rates could increase by 90 percent. Though mass screening is done in few countries, it has not been applied in developing countries like Nepal. Preoperative diagnosis of EGC is rare in Nepal. The aim of this study is to analyze the clinico-pathological features of postoperative cases of gastric cancer managed in a tertiary care university hospital of Nepal.Methods All patients with histological diagnosis of gastric cancer admitted in the Department of Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal during the three year period (September 2010 to August 2013) were analyzed retrospectively.Results Ninety two patients with endoscopic diagnosis of gastric cancers were admitted during the past three years. The mean age was 60 years ranging from 28 years to 85 years with the male to female ratio of 2.8:1. Five patients were younger than 40 years and all were in advanced stage. Thirty five percent of the patients belonged to Janajatis (Hill) community though they comprise only 23% of the population and about 65% of them belonged to an area involving 25% of the country.Seventy six cases were operated. Out of 92 patients, 4 patients were diagnosed as early gastric cancer postoperatively. All patients with early gastric cancer were above 50 years with CT Scan abdomen revealing focal thickening without lymphadenopathy.Conclusion Over the years, the incidence of gastric cancer is increasing in Nepal. Though 92% are advance gastric cancers, few have been diagnosed and treated early. A screening program in a country like Nepal with diverse ethnicity and difficult terrain might be helpful if it targets high risk people in high risk areas.Kathmandu University Medical Journal Vol.12(1) 2014: 32-37


2020 ◽  
Author(s):  
Panji Nkhoma ◽  
Patrick Loti ◽  
Musalula Sinkala ◽  
Hamakwa Mantina ◽  
Florence Mwaba ◽  
...  

Anaemia is a condition in which either the number of red blood cells or their oxygen-carrying capacity is insufficient to meet physiologic needs, which vary by age, sex, altitude, smoking and pregnancy status. The global estimate of childhood anaemia indicates that 293.1 million children are anaemic, and 28.5% of these children reside in sub-Sahara Africa. Also, anaemia is a significant public health problem with a high age standardised death rate of 11.18 per 100,000 in Zambia. We conducted a cross-sectional study involving 392 anaemic children aged one year to 14 years. The study was conducted at the Childrens Hospital, University Teaching Hospitals, which is a third-level referral Hospital in Lusaka, Zambia. The aim was to determine the most common type of anaemia, its severity, and the most affected age groups among children aged 1-14 years. Out of 392 participants, 219 (56%) were female. Maximum haemoglobin recorded was 10.9g/dl, a minimum of 2.0 g/dl, a mean of 7.8g/dl and a standard deviation of 1.86g/dl. 200 (51%) participants had severe anaemia, and 192 (49%) had moderate anaemia with none having mild anaemia. Microcytic hypochromic anaemia was the commonest (60%), followed by normochromic normocytic anaemia (26%) and the least was macrocytic anaemia in 14% of the participants. An analysis of variance (ANOVA) showed that the difference in mean haemoglobin concentration between age groups was not significant, F (7.94) = 0.83, p > 0.57. A Chi-squared test was used to determine the relationship between anaemia types (microcytic, hypochromic) and age groups. The interaction was not significant (Chi-Square (1) = 1.28, p-value = 0.73. Microcytic hypochromic anaemia was the most prevalent and all age groups were equally affected. We recommend the countrys National Food and Nutrition Commission to revisit the Zambian National Strategy and Plan of Action for the Prevention and Control of Vitamin A Deficiency and Anaemia of 1999 to 2004 and implement the measures stated in the strategic plan.


2019 ◽  
Author(s):  
CEDRIC CONTARET ◽  
Raymond CESAIRE ◽  
Jacqueline DELOUMEAUX ◽  
Rémi NEVIERE ◽  
Dabor RESIERE ◽  
...  

Abstract BackgroundBibliometrics are mathematical methods used in various scientific domains to measure scientific output based on the number of publications, the prestige of the journal, and the number of citations of the research after its publication. To the best of our knowledge, only a few bibliometric studies have been performed in the Caribbean or the French West Indies. The aim of this study was to quantify the collaborations and scientific output between the two university teaching hospitals of Martinique and Guadeloupe, at the regional, national and international level.MethodA bibliometrics analysis was performed from the international databases Web of Science and PubMed, for the period from 1989 to 2018 inclusive (30 years). Three types of bibliometric indicators were used, namely quantitative indicators, performance indicators, and organisation-specific indicators. Affiliations of the first and last authors were identified from PubMed. Between 2014 and 2018, we recorded the affiliations of all authors (from the first to the last author) who collaborated on an article with the University Hospital of either Martinique of GuadeloupeResultsBetween 1989 and 2018, a total of 1,522 indexed articles were published with at least one author affiliated to either the University Hospital of Martinique (N=827) or the University Hospital of Guadeloupe (N=685). The majority of articles for both hospitals were in category Q1 (35.8% for Martinique, and 35.2% for Guadeloupe). In Martinique, over the last 30 years, the 3 main research areas have been clinical neurology, ophthalmology and surgery, together representing 28.7% of all research areas, with the highest number of articles published in the field of clinical neurology (n=81). In the University Hospital of Guadeloupe, the area of hematology was largely represented, with 79 articles published. For both hospitals, the first and last authors of the articles published were mainly from mainland France, and from either Martinique or Guadeloupe university hospitalConclusionThis quantitative and qualitative analysis shows the development of medical and scientific research in Martinique and Guadeloupe over the last three decades, as well as the extent of their collaborative partnerships at national and international level.


Author(s):  
Jeffrey D. Forman ◽  
Jonathan Ruby ◽  
Jeanne Parzuchowski ◽  
Peter Littrup ◽  
Arthur T. Porter ◽  
...  

Author(s):  
Takanori Sohda ◽  
Hiroshi Saito ◽  
Goro Asano ◽  
Katsunari Fukushi ◽  
Katsuya Suzuki ◽  
...  

Recently, the functional aspect as well as morphological aspect of the reserve cells in the cervix uteri drew much attention in view of the carcinogenesis in squamocolumunar junction. In this communication, the authors elucidate the ultrastructural features of the reserve cells in patients of various age groups visiting our university hospital and affiliated hospital.From conventional light microscopic point of view, the reserve cells tend to be pronounced in various pathological conditions, such as the persisting inflammation, proliferative disorders and irritation of hormones. The morphological patterns of the reserve cells from various stage and degree of irritation were observed.


2014 ◽  
pp. 47-50
Author(s):  
Duy Binh Ho ◽  
Nghi Thanh Nhan Le ◽  
Maasalu Katre ◽  
Koks Sulev ◽  
Märtson Aare

Aim: This study aimed to review the clinical findings and surgical intervention of the hip fracture at the Hue University Hospital in Vietnam. Methods:The data of proximal femoral fractures was collected retrospectively. All patients, in a period of 5 years, from Jan 2008 to December 2012, suffered either from intertrochanteric or femoral neck fractures. The numbers of patients were gathered separately for each year, by age groups (under 40, 40-49, 50-59, 60-69, 70-79, older) and by sex. We analyzed what kind of treatment options were used for the hip fracture. Results:Of 224 patients (93 men and 131 women) studied, 71% patients are over 70 years old, 103 women and 56 men (p<0.05). For patients under 40 years, there were 1 woman and 11 men (p<0.05). There were 88 intertrochanteric and 136 femoral neck fractures. There was no significant difference in the two fractures between men and women. The numbers of hip fracture increased by each year, 29/224 cases in 2010, 63/224 cases in 2011, 76/224 cases in 2012. Treatment of 88 intertrochanteric fractures: 49 cases (55.7%) of dynamic hip screw (DHS), 14 cases of hemiarthroplasty (15.9%), 2 cases of total hip replacement (2.3%). Treatment of 136 femoral neck fractures: 48 cases of total replacement (35.3%), 43 cases of hemiarthroplasty (31.6%), 15 cases of screwing (11%). In cases of 40 patients (17.9%) hip fracture was managed conservatively, 23 were femoral neck fractures and 17 were intertrochanteric fractures. Conclusions: Hip fracture is growing challenge in Hue medical university hospital. The conservative approach is still high in people who could not be operable due to severe medical conditions as well as for patients with economic difficulties. Over 70% of the hip fractures in people 70+ are caused by osteoporosis. The number of hip fracture is increasing in the following years, most likely due to the increase in the prevalence of osteoporosis. Early detection and prevention of osteoporosis should be addressed, particularly in high risk population. More aggressive surgical approach should be implemented in order to improve the quality of life in patients with hip fractures. Key words:Hip fracture.


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