Egg consumption and blood lipid parameters according to the presence of chronic metabolic disorders: The EVIDENT II Study

Abstract Context Egg consumption is one of the main dietary sources of cholesterol, but whether individuals who eat more eggs have a worse blood lipid profile remains controversial. Objective We examined the relationship between egg consumption and lipid parameters and explored whether this relationship changes according to the presence of chronic metabolic disorders. Methods A multicenter cross-sectional study was conducted with adult participants in the EVIDENT II trial. Adjusted linear regression models were stratified by the main chronic metabolic disorders. Results Among the 728 participants (61.9% women, mean age 52.1±11.9 years), the mean egg consumption was equivalent to 5-to-6 eggs per week for a 70 kg individual. In the fully-adjusted analysis, no association was found of egg consumption with total and HDL cholesterol, and triglyceride levels. Furthermore, compared to the first quartile of consumption, the fourth quartile was associated with lower LDL-c levels (coefficient: -7.01; 95%CI: -13.39, -0.62) and a lower LDL-c/HDL-c ratio (coefficient: -0.24, 95%CI: -0.41, -0.06). In the analyses stratified by chronic metabolic diseases, higher egg consumption was not associated with lipid profile in those with obesity, hypertension, type 2 diabetes, dyslipidemia, or treated with hypolipidemic drugs, and was associated with a better lipid profile in participants without these conditions. Conclusions Higher egg consumption was not associated with blood lipids in individuals with chronic metabolic disorders. In individuals without such conditions, the lipid profile was better among those who consumed more eggs. Our findings support current guidelines recommending eggs as part of a healthy diet.

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HUBUNGAN ASUPAN SERAT DENGAN STATUS GIZI DAN PROFIL LIPID DARAH PADA ORANG DEWASA DISLIPIDEMIA

Jurnal Gizi dan Pangan ◽

10.25182/jgp.2013.8.3.195-200 ◽

2014 ◽

Vol 8 (3) ◽

pp. 195

Author(s):

Lilik Kustiyah ◽

Maya Utami Widhianti ◽

Mira Dewi

Keyword(s):

Nutritional Status ◽

Lipid Profile ◽

Total Cholesterol ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Hdl Cholesterol ◽

Blood Lipid ◽

Cross Sectional Survey ◽

Blood Lipid Profile ◽

Cross Sectional

The objective of this study was to analyze the association of fiber consumption with nutritional status and blood lipid profile in dyslipidemic adults. The design study was cross sectional survey involving 79 subjects. The results showed that there were significant correlations between energy intake with High Density Lipoprotein (HDL) cholesterol and total cholesterol, fat intake with BMI (Body Mass Index), and BMI with Low Density Lipoprotein (LDL) cholesterol and total cholesterol (p<0.05). There was no significant correlation between consumption of fiber with nutritional status and blood lipid profile (p>0.05). In conclusion, most of the dyslipidemia subjects were obese. Dyslipidemia subjects should keep their intake of energy and fat in recommended ranges in order not to be obese and keep the BMI in normal range to avoid abnormalities of blood lipid profile.<br /><br />

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The responses of different dosages of egg consumption on blood lipid profile: An updated systematic review and meta‐analysis of randomized clinical trials

Journal of Food Biochemistry ◽

10.1111/jfbc.13263 ◽

2020 ◽

Vol 44 (8) ◽

Cited By ~ 1

Author(s):

Masoumeh Khalighi Sikaroudi ◽

Sepideh Soltani ◽

Roya Kolahdouz‐Mohammadi ◽

Zachary Stephen Clayton ◽

Maria Luz Fernandez ◽

...

Keyword(s):

Systematic Review ◽

Clinical Trials ◽

Lipid Profile ◽

Randomized Clinical Trials ◽

Meta Analysis ◽

Blood Lipid ◽

Blood Lipid Profile ◽

Egg Consumption

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Blood lipid profile changes in type 2 diabetic rats after tail suspension and reloading

Lipids in Health and Disease ◽

10.1186/s12944-021-01511-y ◽

2021 ◽

Vol 20 (1) ◽

Author(s):

Shoji Tanaka ◽

Sachiko Madokoro ◽

Pleiades Tiharu Inaoka ◽

Toshiaki Yamazaki

Keyword(s):

Lipid Profile ◽

Hdl Cholesterol ◽

Blood Lipid ◽

Tail Suspension ◽

Blood Lipid Profile ◽

Cholesterol Levels ◽

Intramuscular Lipid ◽

Muscle Catabolism ◽

Activity Dependent

Abstract Purpose The effects of the tail suspension and reloading on the protein and lipid metabolism in muscle and blood in type 2 diabetes mellitus (T2DM) are unclear. This study evaluated the hypothesis that skeletal muscle catabolism is greater in T2DM than in non-diabetes mellitus (non-DM) rats and that the activity-dependent changes in the intramuscular lipid accumulation and blood lipid profile are poorer in T2DM than in non-DM rats. Methods T2DM and non-DM rats were suspended for two weeks followed by reloading for two weeks. The muscle and blood were then examined. Results In contrast to our hypothesis, there was no marked difference between the T2DM and non-DM groups in terms of the skeletal muscle catabolism and activity-dependent changes in intramuscular lipid accumulation. However, the blood lipid profile increased in the T2DM group compared to the non-DM group. One interesting finding in this study was the decrease in non-high-density lipoprotein (non-HDL) cholesterol levels after one week of reloading followed by a significant increase in the non-HDL cholesterol levels after two weeks of reloading in the T2DM group. Conclusion These results suggest that a dramatic increase in activity after a period of inactivity may rapidly improve the blood lipid profile in T2DM rats.

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LONG-TERM TRENDS OF THE MAIN BLOOD LIPID PARAMETERS IN SIBERIAN POPULATION

CARDIOVASCULAR THERAPY AND PREVENTION ◽

10.15829/1728-8800-2014-3-32-35 ◽

2014 ◽

Vol 13 (3) ◽

pp. 32-35

Author(s):

Yu. P. Nikitin ◽

S. K. Malyutina ◽

K. V. Makarenkova

Keyword(s):

Lipid Profile ◽

Population Analysis ◽

Blood Lipid ◽

Siberian Population ◽

Blood Lipid Profile ◽

Long Term Trends ◽

The Absolute ◽

Lipid Parameters ◽

Representative Samples

Aim. To carry out the population analysis of blood lipid profile trends during the period from 1985 to 2005 in Novosibirsk population.Material and methods. The study was carried out based on the databases of two large international epidemiological projects done in Novosibirsk, WHO “MONIСA” and “HAPIEЕ”. The representative samples from nonorganized population of Novosibirsk were tested in compliance with protocol of the projects. The analysis included data of 10272 people aged from 45 to 64 years; among them 4783 were men and 5489 — women.Results. Blood TC, non-HDL–C and LDL–С levels from the citizens of Novosibirsk aged 45–64 were significantly lower in the year 1995: 5,50±0,03 mM/l, 4,07±0,03 and 3,48±0,03 mM/l, respectively. By 2005 these values increased significantly and became higher than those initial in 1985. For women 20-year changes in TC, non-HDL–C and LDL–С levels are more prominent than for men. Trends of blood triglyceride levels are analogous to the changes of the indexes described above: average levels were the lowest in 1995 and the highest — in 2005. During a twenty years period the gradual statistically significant increase of blood HDL–C concentrations was noted: in 1985 its concentration was 1,29±0,01 mM/l, in 1995–1,42±0,01 mM/l (p<0,001), in 2005–1,53±0,004 mM/l (p<0,001). HDL–C level for the first decade (1985–1995) increased at average by 10% for the all tenyear period, and for the twenty-year period — by 18,6%, at that for men the increase was more significant (20,2%) than for women (16,4%). By 1995 the absolute values of atherogenicity coefficient decreased significantly; for women in a greater degree. By 2005 the correlation of pro-atherogenic factor to atherogenic one has slightly increased however stayed lower in relation to 1985.Conclusion. In the year 1995 in Siberian population blood TC, non-HDL–C, LDL–С and TG levels appeared to be lower than in 1985 and 2005. Blood HDL–C content was increasing with each decade. Atherogenicity coefficient decreased during the first decade (by 1995), and during the subsequent years slightly increased for women, but did not change significantly for men.

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Community Based Assessment of Biochemical Risk Factors for Cardiovascular Diseases in Rural and Tribal Area of Himalayan Region, India

Biochemistry Research International ◽

10.1155/2013/696845 ◽

2013 ◽

Vol 2013 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Ashok Kumar Bhardwaj ◽

Dinesh Kumar ◽

Sunil Kumar Raina ◽

Pradeep Bansal ◽

Satya Bhushan ◽

...

Keyword(s):

Lipid Profile ◽

Rural Areas ◽

Linear Regression Analysis ◽

Blood Lipid ◽

Multiple Linear Regression Analysis ◽

Cross Sectional Study ◽

Risk Level ◽

Blood Lipid Profile ◽

Cross Sectional ◽

Tribal Area

Context. Evident change in nutrition and lifestyle among individuals of urban and rural areas raises suspicion for similar change in tribal area population of India.Aim. To study the biochemical risk factor for CVDs in rural and tribal population of Sub-Himalayan state of India.Settings and Design. Cross-sectional study in rural (low altitude) and tribal (high altitude) area of Himachal Pradesh, India.Methodology. Blood lipid profile using standard laboratory methods.Statistical Analysis. Chi-square test and multiple linear regression analysis.Results. Total of 900 individuals were studied in both areas. As per Asian criteria, obesity (BMI 27.5–30.0 kg/m2) was observed to be significantly high (P=0.00) as 13.7% in tribal area as compared to 5.5% in rural area. Normal level of TC (<200 mg/dL) and LDL (<130 mg/dL) was observed in the majority of the population of both areas, whereas, at risk level of HDL (<40 mg/dL) was present in half of the population of both rural and tribal areas. The prevalence of borderline to high level of TGs was observed to be 60.2% and 55.2% in rural and tribal (P=0.10) area, respectively.Conclusion. Prevalent abnormal lipid profile in tribal area demands establishment of an effective surveillance system for development of chronic diseases.

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GAMBARAN PROFIL LIPID PADA SISWA OBESE DI SMP NEGERI 1 MANADO

Jurnal e-Biomedik ◽

10.35790/ebm.3.1.2015.6609 ◽

2015 ◽

Vol 3 (1) ◽

Author(s):

Astrid Noviera Iksan ◽

Aaltje Manampiring ◽

Fatimawali .

Keyword(s):

Waist Circumference ◽

Lipid Profile ◽

Total Cholesterol Level ◽

International Diabetes Federation ◽

Blood Lipid ◽

Cross Sectional Study ◽

Observational Method ◽

Blood Lipid Profile ◽

Cross Sectional ◽

Laboratory Results

Abstract: Obesity is an abnormal condition of fat accumulation that can disrupt our health. Obesity problem experienced by some groups of people, one of them is teenager. Blood lipid profile level in obesity children is similar to lipid profile in cardiovascular disease and obesity children also had higher risk of hypertension. Lipid profile is a condition of blood lipid observed by cholesterol total such as LDL, HDL and triglyceride. According to International Diabetes Federation (IDF) criteria, obesity categorized if waist circumference ≥90 cm for male and ≥80 for female. The objective is to determine overview of lipid profile in obese student of SMP Negeri 1 Manado. The research used observational method with cross sectional study, which obesity measured by waist circumference and laboratory results of blood lipid profile level.Based on the waist circumference in 371 populations, there were 97 students included to obesity category and by 97 students, only 13 obesity students took part in the research. There were 2 (15,3%) students had total cholesterol level above normal, 3 (23,1%) students had LDL level above normal, 1 (7,7%) student had HDL level below normal and 2 (15,4%) students hadtriglyceride level above normal.Keywords: obesity, student, adolescents, lipid profile, SMP Negeri 1 ManadoAbstrak: Obesitas merupakan keadaan abnormal penumpukan lemak yang dapat mengganggu kesehatan. Masalah obesitas banyak dialami oleh beberapa golongan masyarakat salah satunya remaja. Kadar profil lipid darah pada anak obesitas menyerupai profil lipid pada penyakit kardiovaskular dan anak yang obesitas mempunyai risiko hipertensi lebih besar. Profil lipid adalah keadaan lemak darah yang ditinjau dari kandungan total kolestrol dalam darah, LDL, HDL dan Trigliserida. Sesuai kriteria International Diabetes federation (IDF) dikategorikan obesitas jika nilai lingkar pinggang ≥90 cm untuk laki-laki dan ≥80 cm pada perempuan. Penelitian ini bertujuan untuk mengetahui gambaran profil lipid pada siswa obesitas di SMP Negeri 1 Manado.Penelitian dilakukan menggunakan metode observasional dengan desain crosssectional study, dimana obesitas diukur berdasarkan lingkar pinggang dan kadar profil lipid di periksa di laboratorium. Berdasarkan hasil pemeriksaan lingkar pinggang pada 371 populasi didapatkan 97 siswa termasuk dalam kategori obesitas dan dari 97 siswa tersebut hanya 13 siswa yang bersedia untuk melakukan pemeriksaan profil lipid. Dari hasil pemeriksaan tersebut didapatkan 2 (15.3%) siswa obesitas memiliki kadar kolestrol total diatas normal, 3 (23.1%) siswa obesitas memiliki kadar LDL diatas normal, 1 (7.7%) siswa obesitas memiliki kadar HDL dibawah normal, dan 2 (15.4%) siswa obesitas memiliki kadar Trigliserida diatas normal. KataKunci : obesitas, siswa, remaja, profil lipid, SMP Negeri 1 Manado

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Content of n-3 LC-PUFA in Breast Milk Four Months Postpartum is Associated with Infancy Blood Pressure in Boys and Infancy Blood Lipid Profile in Girls

Nutrients ◽

10.3390/nu11020235 ◽

2019 ◽

Vol 11 (2) ◽

pp. 235 ◽

Cited By ~ 3

Author(s):

Signe Bruun ◽

Lenie van Rossem ◽

Lotte Lauritzen ◽

Steffen Husby ◽

Lotte Neergaard Jacobsen ◽

...

Keyword(s):

Blood Pressure ◽

Breast Milk ◽

Lipid Profile ◽

Hdl Cholesterol ◽

Blood Lipid ◽

Blood Lipid Profile ◽

Long Term Effect ◽

Maternal Educational Level ◽

Changes Over Time

Blood pressure (BP) and blood lipid profile (BLP) have been shown to track from childhood into adulthood, and n-3 long-chain polyunsaturated fatty acids (LC-PUFAs) in breast milk have been suggested as mediators of the beneficial long-term effect of breastfeeding on BP and BLP. We aimed to investigate associations between n-3 LC-PUFA content in breast milk at 4 months postpartum and offspring BP and BLP in early life. BP and BLP were measured at 4, 18, and 36 months. Statistical analyses were sex-stratified and adjusted for gestational age, maternal pre-pregnancy body mass index (BMI), and maternal educational level. Based on 336 mother-child dyads, high n-3 LC-PUFA in breast milk was inversely associated with systolic and diastolic BP in boys at 4 months (β = −20.0 (95% CI = −33.4, −6.7), p = 0.004 and β = −10.2 (95% CI = −19.8, −0.5), p = 0.039, respectively); inversely associated with HDL cholesterol, and directly associated with triglyceride in girls at 4 months (β = −0.7 (95% CI = −1.1, −0.3), p = 0.001 and β = 3.1 (95% CI = 1.0, 5.2), p = 0.005, respectively). Associations observed at the later time points were non-significant. Furthermore, we observed sex-specific changes over time in both size and direction of the associations. Our results indicate that early intake of n-3 LC-PUFA can affect early development in cardiometabolic factors such as BP and BLP in a sex-specific manner. Follow-up and further investigation in later childhood is planned.

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Comparative Studies of the Effects of Egg Yolk, Oats, Apple, and Wheat Bran on Serum Lipid Profile of Wistar Rats

ISRN Nutrition ◽

10.5402/2013/730479 ◽

2013 ◽

Vol 2013 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

J. O. Omole ◽

O. M. Ighodaro

Keyword(s):

Lipid Profile ◽

Total Cholesterol ◽

Wheat Bran ◽

Serum Lipid ◽

Wistar Rats ◽

Ldl Cholesterol ◽

Hdl Cholesterol ◽

Blood Lipid ◽

Egg Yolk ◽

Blood Lipid Profile

Excess consumption of egg especially its yolk has been implicated in hyperlipidaemia (high level of cholesterol and triglyceride in the blood). Conversely, soluble dietary fibers, probably due to their ability to bind free lipid molecules, appear to play an important role in protecting against hyperlipidaemia. This study sought to evaluate the comparative effects of selected sources of fibers: apple, oats, and wheat bran, on serum lipid profile in physiologically normal Wistar rats. Twenty rats were used for the study and were randomized into four groups, with each containing five animals (). A group which serves as control was fed with egg yolk while the other three groups were fed with apple, oats, and wheat bran, respectively. After two weeks of feeding, the animals were fasted overnight and blood samples from the retro-orbital sinus of the eye were collected for analyses of lipid profile. The results obtained showed that the group fed with oats had the lowest level of total cholesterol ( mg), low density lipoprotein (LDL) cholesterol ( mg), and triglycerides (TG) ( mg), as well as the highest level of HDL cholesterol ( mg). On the contrary, the group fed with egg yolk showed the highest level of total cholesterol ( mg), LDL cholesterol ( mg), and triacylglyceride ( mg), as well as the lowest level of HDL cholesterol ( mg). There was no significant difference () between oats and apple in their effects on blood lipid profile of Wistar rats. Wheat bran, being an insoluble dietary fibre, had less significant () effect on the blood lipid profile when compared to oats and apple. Findings from this study may assist physicians and dieticians in recommending appropriate diet for individuals desiring to normalize their blood lipids levels.

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Two Blends of Refined Rice Bran, Flaxseed, and Sesame Seed Oils Affect the Blood Lipid Profile of Chinese Adults with Borderline Hypercholesterolemia to a Similar Extent as Refined Olive Oil

Journal of Nutrition ◽

10.1093/jn/nxaa274 ◽

2020 ◽

Vol 150 (12) ◽

pp. 3141-3151

Author(s):

Sumanto Haldar ◽

Long Hui Wong ◽

Shia Lyn Tay ◽

Jörg J Jacoby ◽

Pengfei He ◽

...

Keyword(s):

Lipid Profile ◽

Olive Oil ◽

Hdl Cholesterol ◽

Blood Lipid ◽

Chinese Adults ◽

Similar Extent ◽

Blood Lipid Profile ◽

Refined Olive Oil ◽

Oil Blends ◽

Time Treatment

ABSTRACT Background Individual vegetable oils have a characteristic fatty acids (FA) composition and unique phytonutrient profiles, enabling formulation of oil blends that may have health-promoting effects. Objective The primary objective of this study was to investigate effects of 2 oil blends made with refined rice bran, flaxseed, and sesame oils, with distinct monounsaturated to saturated FA, polyunsaturated to saturated FA, and omega-3 (n–3) to omega-6 FA ratios and different phytonutrient concentrations on blood lipid profile, compared with refined olive oil as a control. The secondary outcomes were other markers of cardiometabolic health. Methods A parallel-design, randomized controlled trial compared consumption of 30 g of allocated intervention oil per day for a period of 8 wk. The study recruited 143 borderline hypercholesterolemic (LDL cholesterol: 3.06–4.51 mmol/L) Chinese volunteers between 50 and 70 y old and with a BMI (kg/m2) ≤27.5. All outcomes were measured every 2 wk, and the time × treatment interactions and the main effects of treatment and time were analyzed using an intention-to-treat approach. Results Compared with baseline (week 0), there were significant reductions during the post-intervention time points in serum total cholesterol (−3.47%; P < 0.0001), LDL cholesterol (−4.16%; P < 0.0001), triglycerides (−10.3%; P < 0.0001), apoB (−3.93%; P < 0.0001), total to HDL-cholesterol (−3.44%; P < 0.0001) and apoB to apoA1 (−3.99%; P < 0.0001) ratios, systolic and diastolic blood pressures (−3.32% and −3.16%, respectively; both P < 0.0001), and serum glucose (−1.51%; P < 0.05) and a small but significant increase in body weight (+0.7%; P < 0.001) for all 3 intervention oils but no effects of intervention on HDL-cholesterol or apoA1 concentration. No significant effects of treatment or time × treatment interactions were found. Conclusions Using blended vegetable oils that are extensively consumed in Asia, this study found that specific oil blends can improve blood lipid profile and other cardiometabolic parameters, to a similar extent as refined olive oil, in Chinese adults with borderline hypercholesterolemia. This trial is registered at www.clinicaltrials.gov as NCT03964857.

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Anthocyanin Intake and Physical Activity: Associations with the Lipid Profile of a US Working Population

Molecules ◽

10.3390/molecules25194398 ◽

2020 ◽

Vol 25 (19) ◽

pp. 4398 ◽

Cited By ~ 1

Author(s):

Maria S. Hershey ◽

Mercedes Sotos-Prieto ◽

Miguel Ruiz-Canela ◽

Miguel Angel Martinez-Gonzalez ◽

Aedin Cassidy ◽

...

Keyword(s):

Physical Activity ◽

Lipid Profile ◽

Linear Models ◽

Density Lipoprotein ◽

Hdl Cholesterol ◽

Activity Level ◽

Linear Regression Models ◽

Cvd Risk ◽

Cross Sectional ◽

Validated Questionnaire

While growing evidence exists on the independent associations between anthocyanins and physical activity on cardiovascular disease (CVD) risk determinants, the possible interaction between these exposures has not yet been studied. We aimed to study the potential synergism between anthocyanin intake and physical activity on lipid profile measures. This cross-sectional study was conducted among 249 US career firefighters participating in the Feeding America’s Bravest trial. Anthocyanin intake was calculated using a validated food frequency questionnaire (FFQ) and physical activity level by a validated questionnaire. Multivariable linear regression models determined the extent to which anthocyanin intake and physical activity predicted lipid parameters. Generalized linear models were used for joint effect and interaction analyses on the multiplicative and additive scales. Both anthocyanins and physical activity were independently inversely associated with total cholesterol:high density lipoprotein (HDL) cholesterol. Only physical activity was inversely associated with triglycerides, low density lipoprotein (LDL) cholesterol:HDL, and triglycerides (TG):HDL. Although the combined exposure of low anthocyanin intake and low physical activity was associated with lower (RR = 2.83; 95% CI: 1.42 to 5.67) HDL cholesterol <40 mg/dL, neither multiplicative (p = 0.72) nor additive interactions were detected (relative excess risk due to interaction (RERI): 0.02; 95% CI: −1.63 to 1.66; p = 0.98). Our findings provide insight on the potential synergism between anthocyanin intake and physical activity on the lipid profile.

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