scholarly journals SUN-LB6 Characterization of PCOS Among Flo App Users Around the World

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Isabel Galic ◽  
Dannielle Brown ◽  
Olivia Ruth Negris ◽  
Liudmila Zhaunova ◽  
Anna Klepchukova ◽  
...  

Abstract Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disorder associated with menstrual irregularity and androgen excess. The worldwide prevalence of PCOS among women of reproductive age ranges from 5-20%. Mobile menstrual cycle apps, such as Flo, provide an opportunity to gather data on the characteristics of PCOS in a globally representative and medically unbiased population. The objective of this study was to report PCOS symptomatology relative to country in order to better characterize PCOS and its differing phenotypes among users around the world. A questionnaire on PCOS related symptoms and previous PCOS diagnosis was available to Flo users during one month (2019). The geographical location of the user was estimated based on the IP address. Study inclusion criteria included women aged 18-44 years seeking to track their cycle or to conceive, who were not pregnant, on active contraception, or in stabilization mode after pregnancy and had Flo app running in English. All users in the study had agreed to the use of their de-identified and aggregated data for research purposes.The highest number of Flo app users who completed the PCOS questionnaire were coming from the following top 5 countries: United States (US) (n=240,732), United Kingdom (UK) (n=67,696), India (n=40,171), the Philippines (n=35,097), and Australia (n=28,946). The percentage of self-reported PCOS in these countries was 14.4% with higher percentages in India, the Philippines, and Australia (22.6%, 20.0%, 15.9, respectively) and lower in the US and UK (12.2% and 13.71%, respectively). In the US, UK, and Australia, the most common self-reported symptoms of PCOS positive women were bloating, hirsutism, and irregular cycles. In India and the Philippines, the most common symptoms of women with PCOS were bloating, baldness, and irregular cycles. Hirsutism, high glucose and high levels of both cholesterol and glucose are the three top symptoms increasing the probability of PCOS in all studied countries. The percentage of self-reported PCOS increases 3.04 times among users that reported hirsutism compared to all users that positively responded to the PCOS self-assessment question. Probability of PCOS among users that report hirsutism increases 3.85 times for Australia and 4.24 times for India. Australia and India had higher percentages of self-reported PCOS among those who reported experiencing nearly all PCOS related symptoms. Using Flo’s software, we are able to determine that geographic location has an effect on the phenotypic presentation of PCOS. Understanding the distribution of PCOS symptomology around the world will help to better characterize PCOS and improve diagnosis and treatment on both an individual and global scale.

Author(s):  
Ivan I. Antonovich

The article analyses the main directions and paths of Chinese modernisation, the features of the US’ opposition to it, it is concluded that the success of socialism with Chinese characteristics creates a new world situation in which new socio-economic civilisational foundations can create a society of socialist orientation. It is noted that Deng Xiaoping, without holding any government posts, being only the chairman of the CPC Central Committee’s Defense Committee, led the process of Chinese modernisation, which brought China to the forefront of scientific, technological and social progress in the world. The author argues that the basis of Chinese success is the Leninist formula of the NEP – the use of private entrepreneurship under the control of a socialist state in order to develop at an accelerated rate of social wealth in the amount necessary to meet the basic life needs of its citizens. The path of China was fraught with many unsuccessful and tragic experiments, therefore the current socio-economic leap forward in civilisation is an unprecedented event in world history. The implementation of goals and objectives of such a global scale will make serious changes in the world order, and require a new political philosophy. The success of socialism with Chinese characteristics within the country, as well as in programs to support the progressive development of countries and peoples of the world ready for cooperation, allows us to give a cautious optimistic assessment of the future Chinese perspective. And this, according to the author, is today a clear threat to the tasks and goals of American domination in the world.


2017 ◽  
Vol 2 (2) ◽  
pp. 133
Author(s):  
Anna Rhodora Solar ◽  
John Matthew Poblete

The Philippines had its own share of colonial past. Just as other Asian and African countries which were under the Western colonizers, the Philippines partook of the momentous event that proposed an alternative to the world order dominated by superpowers—the Bandung Conference. The principles collectively known as Bandung Spirit were embraced by the Philippines and had a clear understanding of its symbolic significance. Yet such understanding of these principles was coupled with compromises on the Philippines relations with the United States. Over the decades, the Philippines had to do a balancing act between its being sovereign, independent state and its recognition of the relevance of its past colonial master—the US. Hence, this raises the question of whether the Philippines is living or leaving the Bandung Spirit. Specifically, this paper assesses whether the Philippines still upholds the same Bandung Spirit in its traditional form or has it given a contemporary understanding of it. The paper argues that the Philippine-US relations remain to be an evident display of US presence in Southeast Asia albeit redefined to blend with the Bandung Spirit.


2021 ◽  
Author(s):  
Yi-Ying Chen ◽  
Yibeltal Assefa

Abstract Background: COVID-19 has quickly spread to all corners of the world since its emergence in Wuhan, China in December of 2019. The disease burden has been heterogeneous across regions of the world, with Americas leading in cumulative cases and deaths, followed by Europe, Southeast Asia, Eastern Mediterranean, Africa and Western Pacific. Initial responses to COVID-19 also varied between governments, ranging from proactive containment to delayed intervention. Understanding these variabilities allow high burden countries to learn from low burden countries on ways to create more sustainable response plans in the future.Methods: This study used a mixed-method approach to perform cross-country comparisons of pandemic responses. The chosen countries for this study were the US, Brazil, Germany, Australia, South Korea and Thailand; they were selected based on their income level, relative COVID-19 burden and geographic location. To rationalize the clinical variability between these six countries, a list of 14 indicators was established to systematically assess the countries’ preparedness, actual response, and overall socioeconomic and demographic profile in the context of COVID-19.Results: As of December 1st , 2020, the US had the highest cases per million, followed by Brazil, Germany, Australia, South Korea and Thailand. The same ranking was observed for the countries’ deaths per million statistics. Cross-national comparison suggests that there were nine indicators to explain epidemiological differences between the countries, and they were 1) leadership, governance and coordination of response, 2) communication, 3) community engagement, 4) multisectoral actions, 5) public health capacity, 6) universal health coverage, 7) medical services and hospital capacity, 8) demography and 9) burden of non-communicable diseases.Conclusion: The COVID-19 pandemic manifests varied outcomes due to differences in countries’ vulnerability, preparedness and response. Our study rationalizes why South Korea, Thailand, Australia and Germany performed better than the US and Brazil. By identifying the strengths of low burden countries and weaknesses of hotspot countries, we elucidate specific factors constituting an effective pandemic response that can be adopted by leaders in preparation for re-emerging public health threats.


2019 ◽  
Vol 64 (2) ◽  
pp. 309-323
Author(s):  
Pim de Zwart

Inequality has increased in most Western countries since the early 1980s. In a recent report, the international non-governmental organization Oxfam noted that the twenty-six richest people in the world own as much wealth as the poorest fifty per cent of the world's population. Discontent with the growing disparities in wealth and income has soared in recent years, especially in the wake of the 2007/2008 financial crisis and the “Great Recession” that followed. The Occupy movement protested against the greed of the “one per cent”, referring to the highly skewed income distribution in the US. Former US president Barack Obama proclaimed the growth of within-country economic inequality as “the defining challenge of our time”. Yet, he enacted few policies that reduced inequality during his two terms in office; the Gini coefficient in the US actually increased slightly between 2007 and 2016. His successor, whose election has often been explained as a consequence of these high levels of inequality, has slashed taxes for the wealthy, probably causing further rises in inequality in the future. In this essay, I will review two recent economic history books that examine the historical roots of within-country inequality on a global scale: Branko Milanovic's Global Inequality (2016) and Walter Scheidel's The Great Leveler (2017). Formerly a lead economist at the World Bank, Milanovic is a well-known scholar working in the field of economic inequality, while Scheidel has a background as a specialist in the economic, social, and demographic history of antiquity.


Defendologija ◽  
2020 ◽  
Vol 4 (39-40) ◽  
Author(s):  
Stanislav Stojanović ◽  
Žikica Bardžić

The paper deals with the Asia-Pacifi c region, which is, with its geopolitical andgeostrategic characteristics, one of the most important areas of the modern world, andthe dynamics and character of processes that take place in it have huge implications oninternational politics. The underlying hypothesis of this work is that powerful potentialsof the Asia Pacifi c open up the possibility that it will becomes a true leader of the overallprogress in the world, but the confl icts that exist in that area, of which the most destructiveterritorial disputes are, also have the potential for global scale confrontation.The geostrategic signifi cance, transport corridors, huge reserves of oil and gas,the highest concentration of human resources, as well as high technological achievementsmake the Asia Pacifi c region one of the most powerful drivers of the developmentand progress of the modern world. Such a unique position of the Asian Pacifi c contributesto a strong concentration of the interests of international politics in the region. Of course,the Asia Pacifi c is a place where the most important geopolitical and geo-strategic interestsof the most important actors of contemporary international politics are in confl ict.These circumstances make the region one of the most vulnerable areas of the modernworld in the security sense. Primary causes of the confl ict are economic as well as geostrategiccharacteristics of the area. On the top of the numerous and complex Asian issues,are confl icts between China and the US, which primarily determine the character ofrelations in the region.Authors conclude that US-Chinese rivalry and competition with a progressivetendency are unstoppable and with their complexity are hardly controlled, so there is areal danger of radicalization of their relations, with simultaneous radicalization of relationsacross the region. All these contribute to the fact that relations in the Asia Pacifi cregion are very complicated, often vague and unbalanced and potentially explosive,pushing a region of enormous strategic importance into the labyrinth of multiple instabilitywhose implications would have a powerful refl ection on security in the world. Thearrival of the new US administration announces the toughening of the US bidding withChina as its main competitor, which is causing uncertainty about future security trends inthe Asia Pacifi c region.


Jurai Sembah ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 35-45
Author(s):  
Joelle Florence Patrice Jacinto

Anna Pavlova was the first ballerina to tour the world, effectively globalizing ballet and transforming it from a European/Russian art form into a universal one. The places that she performed in, exotic, war-torn or on the brink of a civil revolt, with either unbearably hot or achingly cold climates, all received her differently, according to the local culture, affecting the ballerina as much as she had an effect on the people who came to see her dance. In most places, such as Cuba, Argentina, the US, Australia, and the Philippines, Pavlova had inspired the localization of ballet in their respective cultures, where appropriation had turned into tradition. This paper looks at how Anna Pavlova accomplished the globalization of ballet as a universal art form, and how it had successfully embedded itself as a local tradition in several countries, specifically in the Philippines, where there exist three professional ballet companies that are still currently active. This paper analyzes Pavlova’s contribution using the concepts of globalization, culture contact, and localization or indigenization.


2021 ◽  
Vol 4 (4) ◽  
pp. 589-604
Author(s):  
Kimberly Woods ◽  
Jillian L. Wendt ◽  
Amy Barrios ◽  
Rebecca Lunde

The current study uses a correlation design and multiple linear regression to determine whether generation, gender, and subject area predict teachers’ technology efficacy as measured by the Technology Proficiency Self-Assessment for 21st Century Leaning (TPSA C-21). An online survey was provided to all participants. The survey consisted of demographic questions and a technology self-efficacy instrument. Results demonstrate that gender and generation are statistically significant predictors of technology efficacy, namely on the Total, WWW, Integrated Applications, and Emerging Technologies Skills subscales of the TPSA C-21. The subject area variable, however, did not demonstrate a statistically significant ability to predict teacher technology efficacy scores on any subscale of the TPSA C-21. The findings of the current study add to the existing body of literature by enhancing understanding of the teachers’ perceptions of technology efficacy in one geographic location in the US. These findings are timely, especially given the largely technology dependent nature of education—whether in physical classrooms or in virtual settings and the increasing necessity of using technological tools in education settings.  Implications are discussed, including suggestions for future research. 


2015 ◽  
Vol 16 (3) ◽  
pp. 563-578 ◽  
Author(s):  
Jadwiga R. Ziolkowska

Since the world's first land-based desalination plant was established in Australia in 1903, brackish groundwater and seawater desalination became a common water supply technology in many countries around the world. Desalination has proven as a reliable technology in times of drought and/or water scarcity, while in some countries it is an indispensable water supply source on a regular basis. This paper compares and evaluates major desalination leaders in the world (USA, Saudi Arabia, Israel, Australia, and China) with the aim of pointing out similarities and differences that made each of them successful. It also depicts a comprehensive picture of developments, trends and experiences in desalination at the global scale. Establishing desalination plants and ensuring their successful operation is a complex and multifaceted process dependent on capital and operational costs, production capacity, water salinity, geographical location, socio-economic and environmental conditions, and many other factors. The country specific comparison presented in this paper emphasizes the importance of regional planning for successful and sustainable desalination processes in the long term.


Asian Survey ◽  
2017 ◽  
Vol 57 (1) ◽  
pp. 135-141 ◽  
Author(s):  
Carolina G. Hernandez

This article explains why the Philippines, a small country and a long-time US ally, shook the world in 2016 by democratically electing a president who has defied conventional expectations, touched the lives of ordinary Filipinos, been accused of human rights violations in his war on drugs, and could affect the geostrategic rivalry between the US and China.


2014 ◽  
Vol 17 (1) ◽  
pp. 78-88
Author(s):  
Luc Tien Nguyen

Recently, China has shown her strong expansionism in East Sea while The US also expresses her determination of implementing the “coming back to Asia” policy. In that context, Japan openly expresses the concerns and actively establishes its role in solving the issues of East Sea. The recent move of Japan is not a single move but in a series of strategic policies of Japan in order to ensure maritime security of Japan as well as restrain the expansionism of China. ASEAN countries such as Vietnam and the Philippines give a cheerful reception toward this move of Japan and hope that Japan can play an active role and more effective in resolving the issue of East Sea dispute. This paper will clarify the following issues: 1. The concern of Japan toward the East Sea Dispute and the move of Japan in the issue. 2. Expectation of ASEAN countries and the world about the role of Japan in resolving the East Sea dispute. 3. From Japan’s perspective of its maritime policy and international relationship strategy, particularly the relationship with the US, China, and ASEAN, the paper will examine whether Japan can meet the expectations of ASEAN countries and the world in resolving the issue of East Sea Dispute.


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