Role of sclerotherapy in vascular malformations

Phlebologie ◽  
2017 ◽  
Vol 46 (02) ◽  
pp. 87-91
Author(s):  
R. Mattassi
Keyword(s):  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Complete Information ◽  
Great Variability ◽  
The Body ◽  
Diagnostic Process ◽  
Lymphatic Malformations ◽  
Sclerosing Agent ◽  
Selection Of

SummaryCongenital vascular malformations (CVM) are a heterogeneous group of vessels defects that include venous, lymphatic, arteriovenous and combined anomalies. CVM may be located in every part of the body with great variability. A precise diagnostic process is required to get complete information about the anomaly prior to decide treatment between different options: surgery, sclerotherapy, embolization and laser. Sclerotherapy has a role in each type of CVM. However, correct indication, selection of the best sclerosing agent, and knowledge of technical skills in CVM are required for a good result. In venous malformations, ethanol is the most effective sclerosing agent but experience in management is required. Lymphatic malformations, mainly in the macrocystic form, can be treated easily with different substances. The nidus of arteriovenous malformations can be occluded by alcohol sclerosis. However, because of the high hemodynamic of AVM, treatment may be difficult; a good sclerosing technique is necessary to avoid complications and to get good results, which are always possible.

The Bodily Self

2018 ◽  
Author(s):  
José Luis Bermúdez
Keyword(s):  
Sense Of Self ◽  
The Body ◽  
The Self ◽  
Behavioral Sciences ◽  
Significant Contributor ◽  
Wide Range ◽  
Physical Objects ◽  
Selection Of

How can we be aware of ourselves both as physical objects and as thinking, experiencing subjects? What role does the experience of the body play in generating our sense of self? What is the role of action and agency in the construction of the bodily self? These questions have been a rich subject of interdisciplinary debate among philosophers, neuroscientists, experimental psychologists, and cognitive scientists for several decades. José Luis Bermúdez been a significant contributor to these debates since the 1990’s, when he authored The Paradox of Self-Consciousness (MIT Press, 1998) and co-edited The Body and the Self (MIT Press, 1995) with Anthony Marcel and Naomi Eilan. The Bodily Self is a selection of essays all focused on different aspects of the role of the body in self-consciousness, prefaced by a substantial introduction outlining common themes across the essays. The essays have been published in a wide range of journals and edited volumes. Putting them together brings out a wide-ranging, thematically consistent perspective on a set of topics and problems that remain firmly of interest across the cognitive and behavioral sciences.

The role of the main ingredients of chocolate in the formation of its beneficial properties for the consumer

2021 ◽  
pp. 582-587
Author(s):  
I.V. Goloviznin ◽  
A.V. Ryzhakova
Keyword(s):  
Human Health ◽  
Complete Information ◽  
The Body ◽  
Specific Product ◽  
Regular Process ◽  
The World ◽  
The Impact ◽  
Confectionery Product

Chocolate is the most staple and consumed confectionery product in Russia and the world. The determination of the beneficial properties of such a product as chocolate is an important and regular process of food institutions in every country, since new lines of already well-known manufacturers and new manufacturers with an innovative assortment are added to the retail assortment. Today, it is very relevant and important to understand the impact of new products on human health. In this regard, in order to provide complete information on a specific product, it is necessary to know its composition, ingredients and their effect on the body separately and within the framework of a specific product. Along with its beneficial properties, chocolate can also affect health negatively. It is necessary to understand the mechanism of the effect of chocolate on human health when consumed and to assess the risks that may arise subsequently after its active consumption.

Management of Metastatic Sarcoma

2017 ◽  
Author(s):  
Ayana Allard-Picou ◽  
Steven C Katz
Keyword(s):  
Soft Tissue ◽  
Individual Characteristics ◽  
The Body ◽  
Low Grade ◽  
Term Survival ◽  
Histologic Subtype ◽  
Metastatic Sarcoma ◽  
Selection Of Patients ◽  
Selection Of

Approximately 12,310 soft tissue sarcomas (STSs) were diagnosed in 2016. These tumors originate from mesenchymal cells throughout the body and account for less than 1% of all newly diagnosed cancers in adults. STSs comprise a heterogeneous group of tumors, with over 50 different histologic subtypes categorized based on the presumptive tissue of origin, each with varying individual characteristics and varying patterns of behavior. Most commonly, they originate in the extremity followed by the trunk as the second most common site of primary lesions. The likelihood of metastatic spread is highly variable among histologic subtype and primary disease site. Distant hematogenous metastases occur in up to 50% of patients with high-grade sarcomas but in only 5% of patients with low-grade sarcomas. Most metastases occur within 2 years following initial diagnosis. The risk of metastasis is dependent on several prognostic factors, including tumor depth, tumor size, and mitotic rate. The role of surgery in the management of metastatic disease is governed by careful patient selection in the context of a multidisciplinary plan including systemic treatment. Selection of patients for resection of sarcoma metastases is most appropriately based on consideration of factors associated with long-term survival. We review the role of surgery in the management of STS metastases, rational selection of patients for resection, and strategies for integrating surgery into multidisciplinary treatment planning for patients with metastatic STS.  This review contains 3 figures, 3 tables and 60 references Key words: gastrointestinal stromal tumor, hepatic sarcoma metastases, metastatic sarcoma, pulmonary sarcoma metastases, retroperitoneal sarcoma, sarcoma, soft tissue sarcoma, surgical resection of sarcoma metastases  

scholarly journals Role of Acupuncturists in Acupuncture Treatment

2007 ◽  
Vol 4 (1) ◽  
pp. 3-6 ◽  
Author(s):  
Tao Liu
Keyword(s):  
Clinical Practice ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Acupuncture Treatment ◽  
Pharmacological Therapy ◽  
The Body ◽  
Diagnostic Process ◽  
Treatment Delivery ◽  
Tcm Theory

Traditional Chinese medicine (TCM) is based on a paradigm of the body different to that of modern biomedicine. Inherent characteristics of TCM necessitate an active and central role of acupuncturists in acupuncture treatment. The author looks at acupuncture in the practical context and analyzes the role of acupuncturists in diagnostic process and treatment delivery. Acupuncture as a complex non-pharmacological therapy depends solely on the acupuncturists' skills, competence and understanding of TCM theory to work. More attention should be given to this important role of acupuncturists in either clinical practice or research on acupuncture.

scholarly journals Histamine and Antihistamines / Histamin i antihistamini

2015 ◽  
Vol 32 (1) ◽  
pp. 7-22
Author(s):  
Nikola Stojković ◽  
Snežana Cekić ◽  
Milica Ristov ◽  
Marko Ristić ◽  
Davor Đukić ◽  
...  
Keyword(s):  
Immune Response ◽  
Immune Cells ◽  
Allergic Diseases ◽  
The Body ◽  
Steady Increase ◽  
Cellular Events ◽  
Th1 And Th2 ◽  
Natural Component ◽  
Selection Of

Summary In recent years, there has been a steady increase in the prevalence of allergic diseases. Allergic immune response represents a complex network of cellular events involving numerous immune cells and mediators. It represents the interaction of innate and acquired immune response. The key role in the immune cascade is taken by histamine, a natural component of the body, which in the allergic inflammatory response is releasesd by the mast cells and basophils. The aim of this study was to highlight the role of histamine in allergic immunological events, their effect on Th1 and Th2 subpopulation of lymphocytes and the production of the corresponding cytokines, as well as the role of histamine blockers in the treatment of these conditions. Histamine achieves its effect by binding to the four types of its receptors, which are widely distributed in the body. Histamine blockers block a numerous effects of histamine by binding to these receptors. As a highly selective second-generation antihistamine, cetirizine not only achieves its effects by binding to H1 receptors, but also attenuates numerous events during the inflammatory process. Knowledge of the effects of histamine blockers, including cetirizine, may lead to the selection of proper therapy for the treatment of allegic diseases.

scholarly journals The Role of Interventional Radiologists in the Treatment of Congenital Lymphatic Malformations

2020 ◽  
Vol 37 (03) ◽  
pp. 285-294
Author(s):  
Julie Cronan ◽  
Anne E. Gill ◽  
Jay H. Shah ◽  
C. Matthew Hawkins
Keyword(s):  
Vascular Malformations ◽  
Pediatric Population ◽  
Mammalian Target Of Rapamycin ◽  
Disease Process ◽  
Low Flow ◽  
Complication Rates ◽  
Management Options ◽  
Lymphatic Malformations ◽  
Percutaneous Sclerotherapy

AbstractLymphatic malformations are low-flow vascular malformations that are typically apparent in the pediatric population and can cause significant functional limitations and effects on quality of life. While surgical resection has historically been the mainstay of therapy, percutaneous sclerotherapy has garnered increasing popularity due to its efficacy and low complication rates. The role of interventional radiology in the multidisciplinary management of these often complex malformations requires thorough understanding of the disease process. This article will review the pathophysiology, clinical presentation, imaging workup, and management options of lymphatic malformations. Special attention will be devoted to available sclerosants, the mammalian target of rapamycin inhibitor sirolimus, and complex lymphatic anomalies.

Delayed Presentation of Lymphatic Malformation of the Cervicofacial Region: Role of Trauma

2002 ◽  
Vol 111 (9) ◽  
pp. 828-831 ◽  
Author(s):  
Reza Rahbar ◽  
Helena Rowley ◽  
Trevor J. McGill ◽  
Antonio R. Perez-Atayde ◽  
Gerald B. Healy
Keyword(s):  
Treatment Options ◽  
Neck Region ◽  
The Body ◽  
Delayed Presentation ◽  
Common Site ◽  
Lymphatic Malformations ◽  
Head And Neck Region ◽  
Airway Compression ◽  
Congenital Lesions

Lymphatic malformations (LMs) are uncommon congenital lesions that may occur throughout the body, although the head and neck region is the most common site. Most LMs are seen at birth. However, they may present in adolescence or adulthood, mainly as a result of trauma or infection. We report the case of a 7-year-old boy who presented with an LM of the cervicofacial region causing airway compression. We discuss the causes of delayed presentation of these congenital lesions. An overview of the causation, natural history, diagnosis, and treatment options is presented.

Genetic tests in lymphatic vascular malformations and lymphedema

2018 ◽  
Vol 55 (4) ◽  
pp. 222-232 ◽  
Author(s):  
Sandro Michelini ◽  
Stefano Paolacci ◽  
Elena Manara ◽  
Costantino Eretta ◽  
Raul Mattassi ◽  
...  
Keyword(s):  
Molecular Diagnosis ◽  
Vascular Malformations ◽  
Phenotypic Variability ◽  
Targeted Sequencing ◽  
Diagnostic Process ◽  
Success Rates ◽  
Clinical Genetic ◽  
Genetic Tests ◽  
Lymphatic Malformations ◽  
Disease Associated Genes

Syndromes with lymphatic malformations show phenotypic variability within the same entity, clinical features that overlap between different conditions and allelic as well as locus heterogeneity. The aim of this review is to provide a comprehensive clinical genetic description of lymphatic malformations and the techniques used for their diagnosis, and to propose a flowchart for genetic testing. Literature and database searches were performed to find conditions characterised by lymphatic malformations or the predisposition to lymphedema after surgery, to identify the associated genes and to find the guidelines and genetic tests currently used for the molecular diagnosis of these disorders. This search allowed us to identify several syndromes with lymphatic malformations that are characterised by a great heterogeneity of phenotypes, alleles and loci, and a high frequency of sporadic cases, which may be associated with somatic mutations. For these disorders, we found many diagnostic tests, an absence of harmonic guidelines for molecular diagnosis and well-established clinical guidelines. Targeted sequencing is the preferred method for the molecular diagnosis of lymphatic malformations. These techniques are easy to implement and have a good diagnostic success rates. In addition, they are relatively inexpensive and permit parallel analysis of all known disease-associated genes. The targeted sequencing approach has improved the diagnostic process, giving patients access to better treatment and, potentially, to therapy personalised to their genetic profiles. These new techniques will also facilitate the prenatal and early postnatal diagnosis of congenital lymphatic conditions and the possibility of early intervention.

Management of Metastatic Sarcoma

2017 ◽  
Author(s):  
Ayana Allard-Picou ◽  
Steven C Katz
Keyword(s):  
Soft Tissue ◽  
Individual Characteristics ◽  
The Body ◽  
Low Grade ◽  
Term Survival ◽  
Histologic Subtype ◽  
Metastatic Sarcoma ◽  
Selection Of Patients ◽  
Selection Of

Approximately 12,310 soft tissue sarcomas (STSs) were diagnosed in 2016. These tumors originate from mesenchymal cells throughout the body and account for less than 1% of all newly diagnosed cancers in adults. STSs comprise a heterogeneous group of tumors, with over 50 different histologic subtypes categorized based on the presumptive tissue of origin, each with varying individual characteristics and varying patterns of behavior. Most commonly, they originate in the extremity followed by the trunk as the second most common site of primary lesions. The likelihood of metastatic spread is highly variable among histologic subtype and primary disease site. Distant hematogenous metastases occur in up to 50% of patients with high-grade sarcomas but in only 5% of patients with low-grade sarcomas. Most metastases occur within 2 years following initial diagnosis. The risk of metastasis is dependent on several prognostic factors, including tumor depth, tumor size, and mitotic rate. The role of surgery in the management of metastatic disease is governed by careful patient selection in the context of a multidisciplinary plan including systemic treatment. Selection of patients for resection of sarcoma metastases is most appropriately based on consideration of factors associated with long-term survival. We review the role of surgery in the management of STS metastases, rational selection of patients for resection, and strategies for integrating surgery into multidisciplinary treatment planning for patients with metastatic STS.  This review contains 3 figures, 3 tables and 60 references Key words: gastrointestinal stromal tumor, hepatic sarcoma metastases, metastatic sarcoma, pulmonary sarcoma metastases, retroperitoneal sarcoma, sarcoma, soft tissue sarcoma, surgical resection of sarcoma metastases  

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