scholarly journals Susceptibility/manifestations of different age groups with various comorbidities to COVID-19 infection

2020 ◽  
Vol 8 (35) ◽  
pp. 7-16 ◽  
Author(s):  
Albin John ◽  
Freedom Ha ◽  
Mimi Zumwalt

The COVID-19 pandemic has taken a great toll on many families. From its rapid spread to debilitating outcomes, the virus has wreaked havoc on healthcare systems around the world. As researchers study this novel virus, the public continues to seek more information on who is the most susceptible and which population will be affected by the more severe manifestations of the disease. As a result, scientists have started analyzing the variable effects of COVID-19 infection in different age groups. While the information is still nascent, these studies demonstrate that no one is immune, that all are susceptible to infection by this virus, and that certain demographics of the general population have more severe disease than others. This literature review examines how COVID-19 has affected different age groups, from neonates to older adults, by exploring statistics, mechanisms, and possible risk factors. This article will also investigate the role of comorbidities in increasing the severity of this viral infection. Key words: COVID-19, SARS-CoV-2, coronavirus, age, neonates, pregnancy, older adults, mechanism, comorbidities, angiotensin converting enzyme 2

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Rashi Sandooja ◽  
Naga Venkata Rama Krishna Vura ◽  
Michael Morocco

Coronavirus disease-19 (COVID-19) can manifest as fever, cough, and shortness of breath and is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Occasionally, these patients may present with diabetic ketoacidosis (DKA). Patients with comorbidities such as diabetes mellitus and hypertension, as well as older age groups, are known to have a more severe disease progression and poor prognosis. In this review article, we attempt to better understand the disease process in diabetics and also discuss potential mechanisms by which diabetes may play a role in disease severity. This includes the effect of diabetes on the immune response and immune dysregulation. The role of diabetes mellitus in molecular processes including augmenting Angiotensin-Converting Enzyme 2 (ACE 2) levels is also discussed as potential mechanisms to explain the grave prognosis seen in these patients.


2019 ◽  
Vol 47 (3) ◽  
pp. 80-91
Author(s):  
V. G. Neiman

The main content of the work consists of certain systematization and addition of longexisting, but eventually deformed and partly lost qualitative ideas about the role of thermal and wind factors that determine the physical mechanism of the World Ocean’s General Circulation System (OGCS). It is noted that the conceptual foundations of the theory of the OGCS in one form or another are contained in the works of many well-known hydrophysicists of the last century, but the aggregate, logically coherent description of the key factors determining the physical model of the OGCS in the public literature is not so easy to find. An attempt is made to clarify and concretize some general ideas about the two key blocks that form the basis of an adequate physical model of the system of oceanic water masses motion in a climatic scale. Attention is drawn to the fact that when analyzing the OGCS it is necessary to take into account not only immediate but also indirect effects of thermal and wind factors on the ocean surface. In conclusion, it is noted that, in the end, by the uneven flow of heat to the surface of the ocean can be explained the nature of both external and almost all internal factors, in one way or another contributing to the excitation of the general, or climatic, ocean circulation.


2011 ◽  
Vol 46 (3) ◽  
pp. 671-685 ◽  
Author(s):  
Richard Drayton

The contemporary historian, as she or he speaks to the public about the origins and meanings of the present, has important ethical responsibilities. ‘Imperial’ historians, in particular, shape how politicians and the public imagine the future of the world. This article examines how British imperial history, as it emerged as an academic subject since about 1900, often lent ideological support to imperialism, while more generally it suppressed or avoided the role of violence and terror in the making and keeping of the Empire. It suggests that after 2001, and during the Iraq War, in particular, a new Whig historiography sought to retail a flattering narrative of the British Empire’s past, and concludes with a call for a post-patriotic imperial history which is sceptical of power and speaks for those on the underside of global processes.


Author(s):  
Milad Zandi ◽  
Saber Soltani ◽  
Mona Fani ◽  
Haniye Shafipour ◽  
Samaneh Abbasi

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relationship between age, severity, and COVID-19 transmission is compared to determine whether there is any reasonable relationship between age and COVID-19. It should be mentioned that some risk factors may increase the probability of developing severe COVID-19 by advancing age, such as pathophysiological changes in the respiratory system, angiotensin-converting enzyme 2 expression in the nasopharynx, and smoking. Susceptibility to SARS-CoV-2 infection is independent of age, but the mortality rate of COVID-19 depends on age.


Educação ◽  
2017 ◽  
Vol 40 (1) ◽  
pp. 73
Author(s):  
Evandro Coggo Cristofoletti ◽  
Milena Pavan Serafim

The economic and political changes in the world, from the 1970s, changed the political education of the Public Institutions of Higher Education in the world. The direction of these changes was clear: the university approachedthe market and the company and created interaction mechanisms that did not exist. The article therefore reviews the academic literature that interprets the relationship between university and market/company from two perspectives: approaches that positively position of interactions, exposing their motivations, interests and forms of interaction, especially the notions on Knowledge Economy and Entrepreneurial University; approaches that observe this interaction critically and reflectively, exposing the problems of interaction, its negative aspects and the reflection of the true role of the public university from the perspective of Academic Capitalism.


2021 ◽  
Author(s):  
Yan Luo

BACKGROUND The depression level among US adults significantly increased during the Coronavirus Disease 2019 (COVID-19) pandemic and age disparity in depression during the pandemic were reported in recent studies. Delay or avoidance of medical care is one of the collateral damages caused by the COVID-19 pandemic and it can lead to increased morbidity and mortality. OBJECTIVE The present study aims to assess the prevalence of depression and delay of care among US middle-aged adults and older adults during the pandemic, as well as investigate the role of delay of care in depression among those two age groups. METHODS This cross-sectional study used the 2020 Health and Retirement Study (HRS) COVID-19 Project (Early, Version 1.0) data. Univariate analyses, bivariate analyses, and binary logistic regression were applied. US adults older than 46 years old were included. Depression was measured by Composite International Diagnostic Interview Short Form (CIDI-SF). Delay of care were measured by four items: delay of surgery, delay of seeing a doctor, delay of dental care, and delay of other care. Univariate analyses, bivariate analyses, and binary logistic regression were conducted. RESULTS More than half of participants were older than 65 years old (58.23%) and 274 participants (8.75%) had depression during the pandemic. Delay of dental care was positively associated with depression among both middle-aged adults (OR=2.05, 95%CI=1.04-4.03, P<0.05) and older adults (OR=3.08, 95%CI=1.07-8.87, P<0.05). Delay of surgery was positively associated with depression among older adults (OR=3.69, 95%CI=1.06-12.90, P<0.05). Self-reported pain was positively related to depression among both age groups. Middle-aged adults who reported higher education level (some college of above) or worse self-reported health had higher likelihood to have depression. While perceived more loneliness was positively associated with depression among older adults, financial difficulty was positively associated with depression among middle-aged adults. CONCLUSIONS This study found that depression among middle-aged and older adults during the pandemic was also prevalent. The study highlighted the collateral damage of the COVID-19 pandemic by identifying the effect of delay of surgery and dental care on depression during the pandemic. Although surgery and dental care cannot be delivered by telehealth, telehealth services can still be provided to address patients’ concern on delay of surgery and dental care. Moreover, the implementation of tele-mental health services is also needed to address mental health symptoms among US middle-aged and older adults during the pandemic. Future research that uses more comprehensive CLINICALTRIAL N/A


Author(s):  
Marina Kameneva ◽  
Elena Paymakova

The article notes that the theme of culture and cultural policy for modern Iran is not a marginal issue. Culture is seen by the country’s leadership as an important component of its state political and ideological doctrine. There is analyzed the role of the Islamic factor and cultural heritage in the cultural policy of the Islamic Republic of Iran over four decades of its existence. Particular attention is paid to the role of the theory of the dialogue of civilizations proposed by M. Khatami as well as to the changing attitude towards it in the public consciousness of Iranian society. It is emphasized that the theme of “Iran and the West” is becoming particularly acute in the country today, contributing to its politicization. An attempt is being made to show that Iranian culture is increasingly becoming an important factor in the foreign policy activities of the leadership of the Islamic Republic of Iran, contributing to the strengthening of the country’s position in the world arena as a whole and the country’s leading role in the region, the realization of the idea of exporting the Islamic Revolution and implementing Iranian cultural expansion outside the country.


Author(s):  
Leti Volpp

The line dividing citizens and those excluded from its promise was long shaped by the public/private dichotomy, consigning women to the private, while reserving citizenship’s sphere of the public domain for men. Feminist theorists, in criticizing this dichotomy, have examined the relationships between citizenship, dependency, and reproduction. While those considered sexually deviant have suffered exclusions from citizenship, gay and lesbian subjects in some sites currently enjoy a role as model citizens. This shift has accompanied a transition in the role of the citizen from producer of work to consumer: the privatized, self-governing, and sexually free individual is today’s prototypical citizen. This new sexual citizen is contrasted with illiberal others, who are cast outside as unfit candidates for citizenship. Queer citizenship does not provide a more encompassing vision; citizenship is not available to be queered, given how it inevitably splits the world into those who belong and those left outside.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S305-S305
Author(s):  
Jenessa C Steele ◽  
Amanda Chappell ◽  
Rachel Scott

Abstract Emotional responses to disrespect tend to be negative (Hawkins, 2015). Little is known about how responses to disrespect vary across age groups and relationship closeness. It is unknown whether older adults have more emotional protection against disrespectful experiences, or are more deeply affected due to relationship closeness. Overall, we might expect that older adults react less negatively to disrespect compared to young adults, as they are more-skilled emotion regulators (Carstensen, 1991; English & Carstensen, 2014). We aimed to explore if, and under which circumstances, older adults are more or less sensitive to disrespect compared to younger adults. Three hundred participants responded to six scenarios illustrating ignored disrespect. Participants were randomly assigned to close or distant relationship disrespect scenarios. Relationship closeness was first determined by requesting participants identify a person in each layer of Kahn and Antonucci’s (1980) Social Convoy Model. Identified names were then automatically inserted into the six scenarios. Emotional responses and sensitivity to each scenario were recorded. Participants in the close condition reported more sensitivity to disrespect and negative emotions than participants in the distant condition. Females reported more sensitivity to disrespect and negative emotions than males. We did not find overwhelming support for age differences in responses to disrespect. A single scenario indicated younger participants more sensitive to disrespect than older participants. Findings suggest it is more hurtful to be disrespected by someone close to you and females may be more sensitive to disrespect than males. More research investigating the role of age in disrespect is needed.


2019 ◽  
Vol 72 ◽  
pp. 03009
Author(s):  
Saassylana Sivtseva ◽  
Olga Parfenova

The historical and cultural heritage, expressed in monuments, architectural structures, dedicated to the Great Patriotic War, today is significant. The purpose of the article is to determine the role of society in perpetuating the memory of the Great Patriotic War. The authors conclude that the events of World War II find a lively response from the public. At the same time, new tendencies in commemorative practices are traced - tragic pages of history that until recently were “uncomfortable” (and in Soviet times banned for research), such as human losses, extremely high mortality of the civilian population from hunger, forcibly transferred to special settlements, - began to be reflected in the construction of monuments, memorable places. The location of these monuments is specific - they were erected at a certain distance from public places, at the territories of churches (victims of famine, victims of political repressions), which is associated with the predicted ambiguity of their perception.


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