Towards a greater understanding of the psychosocial impact of the symptoms of pituitary conditions

Management of pituitary conditions can be problematic with many patients experiencing long-term psychological and social difficulties that impact on their quality of life. This study aimed to identify psychosocial symptoms associated with pituitary conditions that lead to poor quality of life and identify differences in symptomatology between patient groups. A survey using measures of psychological and social symptoms was sent to 2000 members of the Pituitary Foundation in January 2016. The survey was completed by 1062 patients (683 female), aged under 18 to over 65 years, using categorical age ranges. Physical and psychosocial symptoms including appearance issues, fatigue, anxiety and depression were reported. Using correlational and regression analyses, significant variation in symptoms were identified across gender, age range and condition type that were impairing patients' long-term functioning and impacting quality of life. There is a need for greater patient information and advice surrounding psychosocial symptoms of pituitary conditions.

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Long-term Outcome After Survival of a Cardiac Arrest: A Prospective Longitudinal Cohort Study

Neurorehabilitation and Neural Repair ◽

10.1177/1545968317697032 ◽

2017 ◽

Vol 31 (6) ◽

pp. 530-539 ◽

Cited By ~ 20

Author(s):

Véronique R. M. Moulaert ◽

Caroline M. van Heugten ◽

Ton P. M. Gorgels ◽

Derick T. Wade ◽

Jeanine A. Verbunt

Keyword(s):

Quality Of Life ◽

Cardiac Arrest ◽

Cohort Study ◽

Anxiety And Depression ◽

Term Outcome ◽

Long Term Outcome ◽

Prospective Longitudinal ◽

Prospective Longitudinal Cohort

Background. A cardiac arrest can lead to hypoxic brain injury, which can affect all levels of functioning. Objective. To investigate 1-year outcome and the pattern of recovery after surviving a cardiac arrest. Methods. This was a multicenter, prospective longitudinal cohort study with 1 year of follow-up (measurements 2 weeks, 3 months, 1 year). On function level, physical/cardiac function (New York Heart Association Classification), cognition (Cognitive Log [Cog-log], Cognitive Failures Questionnaire), emotional functioning (Hospital Anxiety and Depression Scale, Impact of Event Scale), and fatigue (Fatigue Severity Scale) were assessed. In addition, level of activities (Frenchay Activities Index, FAI), participation (Community Integration Questionnaire [CIQ] and return to work), and quality of life (EuroQol 5D, EuroQol Visual Analogue Scale, SF-36, Quality of Life after Brain Injury) were measured. Results. In this cohort, 141 cardiac arrest survivors were included. At 1 year, 14 (13%) survivors scored below cutoff on the Cog-log. Both anxiety and depression were present in 16 (15%) survivors, 29 (28%) experienced posttraumatic stress symptoms and 55 (52%), severe fatigue. Scores on the FAI and the CIQ were, on average, respectively 96% and 92% of the prearrest scores. Of those previously working, 41 (72%) had returned to work. Most recovery of cognitive function and quality of life occurred within the first 3 months, with further improvement on some domains of quality of life up to 12 months. Conclusions. Overall, long-term outcome in terms of activities, participation, and quality of life after cardiac arrest is reassuring. Nevertheless, fatigue is common; problems with cognition and emotions occur; and return to work can be at risk.

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MNGI-27. THE LONG-TERM DISEASE BURDEN OF MENINGIOMA PATIENTS: RESULTS ON HEALTH-RELATED QUALITY OF LIFE, COGNITIVE FUNCTION, ANXIETY AND DEPRESSION

Neuro-Oncology ◽

10.1093/neuonc/noy148.643 ◽

2018 ◽

Vol 20 (suppl_6) ◽

pp. vi154-vi155

Author(s):

Amir Zamanipoor Najafabadi ◽

Pim van der Meer ◽

Florien Boele ◽

Rob Nabuurs ◽

Johan Koekkoek ◽

...

Keyword(s):

Quality Of Life ◽

Cognitive Function ◽

Disease Burden ◽

Anxiety And Depression ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Low cognitive reserve is associated with chronic migraine with medication overuse and poor quality of life

Cephalalgia ◽

10.1177/0333102414553822 ◽

2014 ◽

Vol 35 (8) ◽

pp. 683-691 ◽

Cited By ~ 9

Author(s):

Marian Gómez-Beldarrain ◽

Ane Anton-Ladislao ◽

Urko Aguirre-Larracoechea ◽

Isabel Oroz ◽

Juan Carlos García-Moncó

Keyword(s):

Quality Of Life ◽

Chronic Migraine ◽

Cognitive Reserve ◽

Medication Overuse ◽

Univariate Analysis ◽

Poor Quality ◽

Anxiety And Depression ◽

Cross Sectional ◽

Sf 36

Objective The objective of this article is to test the hypothesis that cognitive reserve (CR) is related to migraine chronification, medication overuse and poor quality of life in migraineurs. Design/methods A cross-sectional study on patients with chronic migraine with medication overuse (CM-MOH), episodic migraine (EM), and controls, matched by sex, age and education, was carried out. CR was assessed by a specific questionnaire, and quality of life was measured by general and specific questionnaires (SF-36 and MSQoL). Migraine Disability Assessment Scale and Beck questionnaires for depression and anxiety were used. Medication dependence was evaluated by the medication-dependence questionnaire in headache (MDQ-H). Results Fifty-five individuals were enrolled: 18 CM-MOH patients (32.73%), 22 EM patients (40%) and 15 controls (27.27%). Fifty (90.91%) of them were females and aged 43.53 (7.54) years. Univariate analysis showed a significant association between the study group and CR, and all items of the SF-36, anxiety and depression questionnaires, MSQoL and MDQ-H. The lower CR and CM-MOH group were related to a worse quality of life, more anxiety and depression and the highest medication dependence scores. Multivariate analysis showed that higher CR scores were related to higher quality of life as measured by the physical and mental composite scores of the SF-36, and to lower anxiety (beta = −1.08, p = 0.001) and depression (beta = −0.56, p = 0.03) levels. Focusing on MSQoL, the increase in CR was predictive of a better quality of life (beta = 1.88, p < 0.0001). By all the models, the explained variance of the sample ranged from 39% (mental composite score) to 58% (MSQoL). Conclusions Low CR appears to be an independent factor associated with the deterioration of quality of life, the presence of anxiety and depression, and drug dependence and medication overuse in CM-MOH.

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The Impact of Schizotypy on Quality of Life Among Adults with Autism Spectrum Disorder

10.21203/rs.3.rs-659129/v1 ◽

2021 ◽

Author(s):

Albin Klang ◽

Britta Westerberg ◽

Mats B. Humble ◽

Susanne Bejerot

Keyword(s):

Quality Of Life ◽

Autism Spectrum Disorder ◽

Autistic Traits ◽

Poor Quality ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Anxiety And Depression ◽

Schizotypal Personality ◽

The Impact

Abstract Background: Autism spectrum disorder (ASD) and schizotypal personality disorder can be difficult to distinguish. Deficits in social relationships and social interaction, present in both conditions, are known to impair quality of life. The aim of the present study was to investigate if schizotypal symptoms affect quality of life among adults diagnosed with autism spectrum disorder and to study the association between schizotypy and autistic traits among them. Methods: Participants diagnosed with autism spectrum disorder (n=110) completed questionnaires exploring schizotypy (Schizotypal Personality Questionnaire – Brief Revised (SPQ-BR)), autistic traits (The Ritvo Autism, Asperger Diagnostic Scale-Revised Screen 14 items), anxiety and depression (The Hospital Anxiety and Depression scale) and quality of life (Brunnsviken Brief Quality of Life Scale and the European quality of life index version 5D). Results: Schizotypy was found to be associated with anxiety, depressive and autistic symptoms, and poor quality of life. Although schizotypy was a predictor for impaired quality of life, this relationship was mediated by symptoms of anxiety and depression, plausibly inherent to autism. Autistic traits were positively associated with all higher order constructs of the SPQ-BR, i.e. positive and negative schizotypy, disorganization and social anxiety, as well as with poor quality of life. Conclusions: There is considerable overlap between schizotypy and autism that needs to be considered in research. Prominent schizotypal traits in people with ASD may constitute an endophenotype coinciding with a particularly poor quality of life.

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Long-term change in health-related quality of life in patients with asthma

Russian Pulmonology ◽

10.18093/0869-0189-2018-28-6-708-714 ◽

2019 ◽

Vol 28 (6) ◽

pp. 708-714

Author(s):

N. L. Perel’man ◽

V. P. Kolosov

Keyword(s):

Quality Of Life ◽

Emotional Disorders ◽

Asthma Control ◽

Social Activity ◽

Anxiety And Depression ◽

Cold Air ◽

The Social ◽

Activity Domain

The aim of this study was to investigate long-term change in health-related quality of life (HRQL) in patients with asthma in real clinical practice and in relation to emotional disorders, cooperativeness (cooperation between the patient and the physician, and adherence to treatment), and cold air-provoked bronchial hyperresponsiveness (BHR).Methods. This observational study involved 32 patients with mild to moderate asthma. The study duration was 7.5 to 10 years. HRQL was assessed using SF-36 questionnaire and Asthma Quality of Life Questionnaire (AQLQ); emotional disorders were diagnosed using Hospital Anxiety and Depression Scale (HADS). Patients’ cooperativeness assessment was based on number of a patient’s scheduled visits to a physician during the study. The asthma control level was evaluated using the Asthma Control Test (ACT).Results. A significant worsening was found in the social activity domain of HRQL in the total group of the patients. According to AQLQ, a significant improvement was seen in the activity and symptoms domains and in the total score of quality of life (QoL). Long-term pharmacological treatment of asthma decreased anxiety and depression levels. The asthma control (ACT score) increased from 13.2 ± 1.0 to 19.7 ± 1.1 (р = 0.00003). Anxiety and depression decreased in patients with high cooperativeness during the long-term follow-up, while the total QoL and the specific QoL were unchanged excluding the social activity domain. A significant worsening in the activity scale and in the emotional scale of specific QoL together with growing depression and decreasing control of asthma were found in patients with lower cooperativeness. The cold air-provoked BNR slowed down the long-term improvement in the social activity domain. The cold air-provoked BNR also decreased patient-reported evaluation of daily activity.Conclusion. The long-term basic therapy of asthma provides a positive trend in HRQL in the real clinical practice independently on worsening of the disease. Lower cooperativeness of a patient could decrease specific QoL, which, in turn, worsens the control of asthma and contributes to negative emotional background and destructive behavior.

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Anxiety, depression and quality of life in mothers of intellectually disabled children

Journal of Psychiatrists Association of Nepal ◽

10.3126/jpan.v6i2.21757 ◽

2018 ◽

Vol 6 (2) ◽

pp. 28-35

Author(s):

N Sapkota ◽

A K Pandey ◽

BK Deo ◽

MK Shrivastava

Keyword(s):

Quality Of Life ◽

Intellectual Disability ◽

Poor Quality ◽

Anxiety And Depression ◽

Disabled Children ◽

Intellectually Disabled ◽

Icd 10 ◽

Anxiety Depression ◽

The Relationship

Introduction: Studies have shown that there is an association between Anxiety, Depression in mothers of children having Intellectual disability with poor quality of life (QOL) in mothers of such children. This study was carried with the objectives to describe the clinico-socio-demographic profile of mothers of intellectually disabled children and to investigate the relationship among anxiety and depression with quality of life in mothers with intellectually disabled children.Material And Method: Mothers (N=31), whose children's IQ score was below 70, were enrolled in to the study with their informed consent. Depression and Anxiety disorders were diagnosed as per ICD 10. Severity of depression was measured with BDI and Anxiety symptoms with STAI. WHOQOL-BREF was used to assess Quality of life. The relationship among anxiety, depression and QOL were analysed using diagonal matrix, ANOVA and Pearson correlation test.Results: The mean age of participants was 50.23 (S.D= 6.11), BDI score was 13.65(S.D= 11.301), STAI score was 53.90 (SD= 15.821), WHOQOL- BREF in all four domains was 290.90 (S.D=49.42). There was significant correlation between BDI and STAI (P=0.01, r:0.651 ) and the three domains of WHOQOL- BREF(P=0.01, r:0.821, 0.843, 0.635 respectively) scale except Environment domain. Among the participants, 48.4% (ICD 10) had depression of varying degree along with 54.8% depression as per BDI cut off score. Anxiety disorder was seen in 22.6% as per ICD 10 but as per STAI it was 53.90(SD=15.821) which was statistically significant (p:0.01, r: -0.507). Depression when compared with no diagnosis persons has poor quality of life in WHOQOL-BREF physical domain (p:0.002) but with compared to Anxiety or both it was not statistically significant.Conclusion: The findings of this study revealed that mothers of children having Intellectual disability have high level of Anxiety and Depression which indeed had impact in quality of life. J Psychiatrists’ Association of Nepal Vol. 6, No. 2, 2017 Page: 28-35

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Predictors of quality of life, symptoms of anxiety, and depression in Latino patients with cervical cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.34_suppl.171 ◽

2018 ◽

Vol 36 (34_suppl) ◽

pp. 171-171

Author(s):

Oscar Galindo Vazquez ◽

Mayra CU Menes ◽

David Ortiz ◽

Abelardo Meneses-Garcia ◽

Jose Luis Aguilar ◽

...

Keyword(s):

Quality Of Life ◽

Cervical Cancer ◽

Depression Scale ◽

Psychosocial Care ◽

Poor Quality ◽

Anxiety And Depression ◽

Chi Square ◽

European Organization ◽

Exact Test

171 Background: Cervical cancer is considered one of the most frequent cancers among women and with the greatest causes of death in the world. In Mexico it is considered the second cause of death. Objective: The identify predictors of quality-of-life, symptomatology of anxiety and depression in patients with cervical cancer. Methods: 192 patients with cervical cancer aged between 44 and 60 years were included, through interview and consultation of the clinical file, information on sociodemographic and clinical variables were obtained. Instrument: European Organization Scale for Cancer Research and Treatment and Quality of Life (EORTC QLC-C30) and Hospital Anxiety and Depression Scale (HADS). Statistical analysis: Chi square or Fisher´s exact test. The association of the variables was evaluated by logistic regression analysis. Results: 48% had poor quality of life, 24% with depression, and 29% with anxiety.The predictors of a low quality of life are: presenting one or more comorbidities, family history with cancer, presenting anxious, and depressive symptoms Conclusions: Psychological assumptions are predictors of variables such as quality of life, in a population with cervical cancer, in Mexico this group of patients have low educational and economic levels. Psychosocial care programs are required in this group of Latina women.

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PROFIL KUALITAS HIDUP DAN TEKANAN DARAH PASIEN HIPERTENSI RAWAT JALAN DI RSUD ULIN BANJARMASIN

Jurnal Ilmiah Manuntung ◽

10.51352/jim.v4i2.189 ◽

2018 ◽

Vol 4 (2) ◽

pp. 106

Author(s):

Riza Alfian ◽

Nani Lisdawati ◽

Aditya Maulana Perdana Putra ◽

Ratih Pratiwi Sari ◽

Fahma Lailani

Keyword(s):

Quality Of Life ◽

Blood Pressure ◽

Poor Quality ◽

Term Treatment ◽

Survey Method ◽

Inclusion Criteria ◽

Long Term Treatment ◽

Blood Pressure Data

Hypertension is one of the main factors of coronary heart disease and stroke. The prevalence of hypertension in South Kalimantan Province occupied a second prevalence of 30,8%. Hypertension is a chronic disease that requires long-term treatment. Furthermore, long-term treatment of anti-hypertension patients also have the possibility of side effects that also affect the quality of life of patients. Uncontrolled blood pressure can aggravate the incidence of hypertension and develop into a more dangerous disease that affects the quality of life of patients. The purpose of this study was to determine the description of blood pressure and quality of life of outpatient hypertensive patients at RSUD Ulin Banjarmasin. This research was conducted by using survey method. Sampling was done by consecutive sampling method. Samples meeting the inclusion criteria were 61 patients. The sample inclusion criteria were outpatients ages 18-65 with hypertension diagnoses, and were willing to follow the study. Exclusion criteria were patients with uncooperative, illiterate and deaf conditions. Data collection was done by interviewing and filling out the EQ-5D questionnaire. Blood pressure data were taken from medical records. The data of the research are presented in descriptive form. Based on this research can be concluded that the value of systolic blood pressure and diastolic mean of research sample is 153,82 ± 17,62 and 86,16 ± 10,52 mmHg. The study sample was dominated by patients with level II hypertension (52,5%). Furthermore the quality of life of the average sample was dominated by the category of poor quality of life (73,8%).

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P05.65 The caregiver burden in meningioma: long-term results and its effects on caregiver’s health-related quality of life, anxiety and depression

Neuro-Oncology ◽

10.1093/neuonc/noy139.391 ◽

2018 ◽

Vol 20 (suppl_3) ◽

pp. iii318-iii318

Author(s):

A H Zamanipoor Najafabadi ◽

P B van der Meer ◽

F W Boele ◽

J C Reijneveld ◽

M J B Taphoorn ◽

...

Keyword(s):

Quality Of Life ◽

Caregiver Burden ◽

Long Term Results ◽

Anxiety And Depression ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Patient-reported outcomes are independent predictors of one-year mortality and cardiac events across cardiac diagnoses: Findings from the national DenHeart survey

European Journal of Preventive Cardiology ◽

10.1177/2047487318769766 ◽

2018 ◽

Vol 26 (6) ◽

pp. 624-637 ◽

Cited By ~ 16

Author(s):

Selina K Berg ◽

Charlotte B Thorup ◽

Britt Borregaard ◽

Anne V Christensen ◽

Lars Thrysoee ◽

...

Keyword(s):

Quality Of Life ◽

Hospital Discharge ◽

Patient Reported Outcomes ◽

Severe Symptom ◽

Poor Quality ◽

Anxiety And Depression ◽

Cardiac Events ◽

Patient Reported ◽

One Year

Aims Patient-reported quality of life and anxiety/depression scores provide important prognostic information independently of traditional clinical data. The aims of this study were to describe: (a) mortality and cardiac events one year after hospital discharge across cardiac diagnoses; (b) patient-reported outcomes at hospital discharge as a predictor of mortality and cardiac events. Design A cross-sectional survey with register follow-up. Methods Participants: All patients discharged from April 2013 to April 2014 from five national heart centres in Denmark. Main outcomes Patient-reported outcomes: anxiety and depression (Hospital Anxiety and Depression Scale); perceived health (Short Form-12); quality of life (HeartQoL and EQ-5D); symptom burden (Edmonton Symptom Assessment Scale). Register data: mortality and cardiac events within one year following discharge. Results There were 471 deaths among the 16,689 respondents in the first year after discharge. Across diagnostic groups, patients reporting symptoms of anxiety had a two-fold greater mortality risk when adjusted for age, sex, marital status, educational level, comorbidity, smoking, body mass index and alcohol intake (hazard ratio (HR) 1.92, 95% confidence interval (CI) 1.52–2.42). Similar increased mortality risks were found for patients reporting symptoms of depression (HR 2.29, 95% CI 1.81–2.90), poor quality of life (HR 0.46, 95% CI 0.39–0.54) and severe symptom distress (HR 2.47, 95% CI 1.92–3.19). Cardiac events were predicted by poor quality of life (HR 0.71, 95% CI 0.65–0.77) and severe symptom distress (HR 1.58, 95% CI 1.35–1.85). Conclusions Patient-reported mental and physical health outcomes are independent predictors of one-year mortality and cardiac events across cardiac diagnoses.

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