scholarly journals The Indifference of Daily Wearing of Corrective Linen in Relation to Platelet Activity in Women of Second Adulthood with First Degree Hypoid Obesity

2018 ◽  
Vol 11 (4) ◽  
pp. 1975-1981
Author(s):  
A.A. Bikbulatova ◽  
I.N. Medvedev
Keyword(s):  
Platelet Aggregation ◽  
Developed Countries ◽  
Modern Medicine ◽  
Common Condition ◽  
Platelet Activity ◽  
Dietary Restrictions ◽  
Working Age ◽  
The Given ◽  
Mechanical Influence ◽  
Visual Correction

Despite the long and systematic efforts of modern medicine, obesity in women in developed countries is still a fairly common condition. Particular attention to this problem is caused by an increase in recent years in the number of cases of this pathology among women of working age who do not have the opportunity to regularly visit fitness halls and comply with various dietary restrictions. In this connection, the problem arises of cosmetic correction of their figures with minimal costs and efforts on the part of women. An exit from the given situation can be wearing corrective clothes, capable to lower volumetric sizes of a body by mechanical influence on it in problem sites. In the work, an evaluation was made of the safety of prolonged wearing of the author's version of the trousers, taking into account hematological and haemostasiological indices. It was found that in women with obesity of grade 2, who received this correction, there was a persistent retention of the measured values ​​within the limits of the norm. The use of the author's version of corrective clothing in women with obesity was accompanied by a visual decrease in the size of their body at the place of wearing the used product. At the same time they had a stably normal level of platelet aggregation, corresponding to the values ​​of control. The obtained results allow to consider the author's corrective clothing as a full and safe component of visual correction of obesity manifestations in women.

scholarly journals Russian mortality trends in the early XXI century: official statistics data

2011 ◽  
Vol 10 (6) ◽  
pp. 5-10 ◽  
Author(s):  
S. A. Shalnova ◽  
A. D. Deev
Keyword(s):  
Marked Decrease ◽  
Developed Countries ◽  
Absolute Number ◽  
Modern Medicine ◽  
Mortality Trends ◽  
Positive Tendency ◽  
National Mortality ◽  
All Cause Mortality ◽  
Working Age ◽  
Cvd Mortality

From the second half of the XX century, cardiovascular disease (CVD) remains one of the main problems of the modern medicine. Over the last two decades, developed countries demonstrated a marked decrease in all-cause mortality and CVD mortality, in particular. InRussia, since the mid-1960s, all-cause mortality gradually increased, with the proportion of CVD deaths being over 50 %, which led to unparalleled high levels of national mortality. In 2009, the absolute number of CVD deaths was 1136661, or 1 case out of 1,8. In other words, 3114 Russian people die from CVD every day. From 2004, all-cause mortality, including CVD mortality, started to decline, and this tendency has continued until at least 2009, as demonstrated by the mortality rate of 801 per 100,000. However, the mortality levels are still higher than in the late 1980s. The authors analysed the CVD dynamics between 2003 (the highest levels) and 2009 inclusive, using the official national statistics data. The last few years demonstrated a positive tendency of declining mortality. In particular, the all-cause mortality (deaths per 100,000) decreased from1644,2 in2003 to1416,8 in2009 (by 13,8 %). CVD mortality decreased by 13,6 %, and more markedly mostly in working-age people (by 18,9 %). Therefore, in 2009, the number of lives saved due to the decreasing CVD mortality was 260741. Further studies will explain the recent mortality trends inRussia.

scholarly journals Maintaining a Normal Level of Plasma Bioregulators on the Background of Daily Wearing Corrective Underwear in Women with Developing Gynoid Obesity

2019 ◽  
Vol 12 (2) ◽  
pp. 689-695
Author(s):  
Albina Ahatovna Bikbulatova
Keyword(s):  
Plasma Level ◽  
Modern Society ◽  
Developed Countries ◽  
The Body ◽  
Normal Range ◽  
Current Increase ◽  
Dietary Restrictions ◽  
Body Sizes ◽  
Minimal Effort ◽  
Visual Correction

In modern society, obesity in women in developed countries retains its widespread prevalence. Much attention to this problem is caused by the current increase in the number of cases of obesity among middle-aged women who are not able to regularly experience muscular loads in the form of exercises and comply with various dietary restrictions. In this regard, there is a need for cosmetic correction of their figure in the presence of minimal effort on the part of women with signs of obesity. The solution to this problem may be the wearing of corrective clothing, which is able to effectively reduce the volume dimensions of the body through a soft mechanical impact on it in problem areas. In the work carried out, the safety assessment of the long wearing of the author's version of the trousers was carried out taking into account the dynamics of the plasma level of functionally significant hemostasis biregulators for half a year. It was found that women with obesity 1 degree, wearing corrective clothing, there was a persistent preservation of the indicators taken into account within the normal range. The great advantage of using the author's version of corrective clothing for women with obesity was the upcoming visual reduction of their body sizes in the area of ​​application of the product. At the same time, all women under observation maintained a consistently normal plasma level of hemostasis regulators corresponding to the control values. The results obtained allow us to consider the author's corrective clothing as a complete and safe component of the visual correction of the manifestations of developing obesity in women.

Population Policies in Turkey and Demographic Changes on a Social Map

2016 ◽  
Vol 6 (2) ◽  
pp. 240-266 ◽  
Author(s):  
Mustafa Murat Yucesahin ◽  
Tuğba Adalı ◽  
A Sinan Türkyılmaz
Keyword(s):  
Population Policy ◽  
Developed Countries ◽  
Ageing Population ◽  
Demographic Changes ◽  
Demographic Transitions ◽  
Population Policies ◽  
Demographic Indicators ◽  
The Social ◽  
Working Age ◽  
Low Levels

Compared to its past structure, Turkey is now a country with low levels of fertility and mortality. This junction that Turkey now has reached is associated with a number of risks, such as an ageing population, and a decreasing working-age population. The antinatalist policy era of Turkey was followed by a period of maintenance, yet the recent demographic changes formed the basis of a pronatalist population policy from the government’s view. This study discusses the link between demographic change and population policies in Turkey. It further aims to position Turkey spatially in relation to selected countries that are in various stages of their demographic transitions with different population policies, using a multidimensional scaling approach with data on 25 selected countries from the UN. The analysis is based on a 34-year period, 1975-2009, so as to better demonstrate Turkey’s international position on a social map, past and present. Our findings suggest that Turkey’s position on the social map shifted towards developed countries over time in terms of demographic indicators and population policies. 

Ayurvedic Management of Dry Eye Sydrome - A Case Study

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Hemalatha S. ◽  
Rati S.
Keyword(s):  
Dry Eye ◽  
Treatment Modality ◽  
Similar Condition ◽  
Symptomatic Relief ◽  
Tear Film ◽  
Modern Medicine ◽  
Common Condition ◽  
Dry Out ◽  
Tear Substitute

Dry eye syndrome is a common condition that results from reduced tear production or excessive tear evaporation or an abnormality in the production of mucus or lipids normally found in the tear layer or combination of these. If blinking is decreased or if the eyelids cannot be closed, they may dry out leading to dry eye. It is accompanied by increased osmolarity of the tear film and inflammation on the surface of the eye may occur of left untreated leading to pain, ulcers or scars on the cornea and loss of vision. Prevalence of dry eye range from 5% to 35% worldwide while in India it is 29.25%. Tear substitute are the only treatment modality with modern medicine, only providing symptomatic relief. Ayurveda describes similar condition called Sushkakshi Paka and this patient was treated with Tarpana and Nasya with Jeevantyadi Ghrita.

scholarly journals ROLE OF NITRIC OXIDE (NO) IN CAPSAICIN MEDIATED ANTI-PLATELET ACTIVITY IN IN VITRO, IN VIVO, EX-VIVO MODEL OF PLATELET AGGREGATION ASSAY AND ARTERIAL THROMBOSIS IN RAT: POTENTIAL THERAPEUTIC TARGET?

2018 ◽  
Vol 10 (4) ◽  
pp. 44
Author(s):  
Mihir K Patel ◽  
Kiranj K. Chaudagar ◽  
Anita A. Mehta
Keyword(s):  
Platelet Aggregation ◽  
Arterial Thrombosis ◽  
Ex Vivo ◽  
Platelet Activity ◽  
Aggregation Assay ◽  
Thrombosis Model ◽  
Platelet Aggregation Assay

Objective: Although recent advances in the treatment of congestive heart disease, mortality among patients’ remains a questionable remark. Therefore, we evaluated the role of capsaicin on in vitro and ex vivo platelet aggregation induced by Adenosine Di-Phosphate (ADP) as well as in in vivo thrombosis models and role of NO, KATP was also identified in the capsaicin-induced anti-platelet animal model as well as in vivo model of arterial thrombosis.Methods: According to body weight wistar rats were divided into five groups. Group I and Group II was treated with saline and capsaicin (3 mg/kg, i. v), while animals from Group III were treated with N(ω)-nitro-L-arginine methyl ester (L-NAME) (30 mg/kg, i. v) 30 min before administration of capsaicin (3 mg/kg, i. v). Group IV animals were treated with glibenclamide (10 mg/kg,i. v) 30 min before administration of capsaicin (3 mg/kg, i. v). Group V was considered as a positive control and administered clopidogrel (30 mg/kg, p. o). Animals were subjected for in vitro, ex-vivo platelet aggregation assay. ADP (30µM) was utilized as an aggregating agent in these experiments. After these assays; animals of each group were subjected for subaqueous tail bleeding time in a rat model and FeCl3-induced arterial thrombosis model in rats.Results: In ADP-induced in vitro platelet aggregation, a significant reduction in % platelet aggregation was observed at 50µM (64.35±4.641) and 100µM (52.72±4.192) concentration of capsaicin as compared to vehicle control (85.82±3.716). Capsaicin (3 mg/kg, i. v) also showed a significant reduction (49.53±4.075) in ex-vivo ADP-induced platelet aggregation as compared to vehicle control (89.38±2.057). In FeCl3 induced arterial thrombosis model, Capsaicin (3 mg/kg, i. v) exhibited an increase in time to occlusion in this rodent model and presence of the L-NAME and glibenclamide had inhibited the activity of capsaicin.Conclusion: In our study, capsaicin (50 µM, 100µM) exhibited potent anti-platelet activity in ADP-induced platelet aggregation, similarly capsaicin exhibited significant anti-platelet action in the ex-vivo study. Moreover, the presence of L-NAME and glibenclamide inhibited the anti-thrombotic and anti-platelet action of capsaicin. Therefore, it was concluded that NO and KATP may be involved in the anti-thrombotic action of capsaicin.

scholarly journals Osteopathic correction in the treatment of pain in the lower back

2020 ◽  
pp. 140-146
Author(s):  
V. O. Belash ◽  
Yu. O. Novikov
Keyword(s):  
Back Pain ◽  
Developed Countries ◽  
Economic Problem ◽  
World Health ◽  
Randomized Controlled ◽  
Lower Back ◽  
The World ◽  
Working Age ◽  
Acute Back Pain ◽  
Health Organization

According to experts of the World Health Organization the lower back pain (LBP) prevalence in developed countries reaches the pandemic size, and it is a serious medical and socio-economic problem. Acute back pain is transformed into chronic in 10–20 % of working age patients′ cases; this causes serious psychological disorders appearing, forms painful behavior and persists even when the initial pain trigger is eliminated. Data from metaanalyses of randomized controlled trials indicate the effectiveness of the osteopathic approach in the treatment of LBP patients. At the same time the osteopathic correction is effective not only for acute pain, but also for chronic pain. A case from clinical practice is described demonstrating the possibility of osteopathic correction of a LBP patient.

scholarly journals The Peculiarities of Civil-Legal Regulation of Transplantation in Ukraine and Europe

2018 ◽  
Vol 8 (1) ◽  
pp. 33-48
Author(s):  
Alla Herts
Keyword(s):  
Treatment Process ◽  
Developed Countries ◽  
Legal Regulation ◽  
Modern Medicine ◽  
The Body ◽  
Accessibility Of Health Services ◽  
Surgical Field ◽  
Processed Form ◽  
The Cost ◽  
Cadaveric Transplantation

Abstract In modern realities the issue of the quality and accessibility of health services, the cost of medicines, examinations and treatment in general is being increasingly frequently discussed. The attention is focused on such a narrow surgical field as transplantation, because in Ukraine thousands of patients are waiting in line for organ transplantation and very few operations are performed. The main, most secure and common type of transplantation is the transplantation of organs and tissues from a deceased person, the dead body. Cadaveric transplantation, which is used in most developed countries, is hardly carried out in Ukraine. This is due to the fact that the current regulatory base of Ukraine in the field of transplantation does not fully meet the needs of modern medicine and has many gaps. The aim of donation is a future transplantation (including and in cases of blood transfusion and reproductive cells use). The parts (tissues, organs, their parts, individual cells) extracted (separated) from the body in the process of donation can be used generally in the treatment process in a processed form (blood plasma) or in the original state (fertilized reproductive cells). The detailed analysis of the provisions of the national legal system makes it possible to conclude that, despite the absence of direct regulation of relations concerning organ donation and transplantation as material relations, the legal regulations provide the fundamental provisions, which determine their material nature, and therefore offer opportunities for agreementbased regulation. In our opinion, one of the essential legal means of ensuring the rights of participants in the relations of donation and transplantation can be their agreement-based regulation. The peculiarities of civil-legal regulation of transplantation in Ukraine and Europe are simultaneously analysed; and the grounds of its legitimacy are defined.

scholarly journals Antithrombotic Effect of the Ethanol Extract of Angelica gigas Nakai (AGE 232)

Life ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 939
Author(s):  
Pia Loreto Werlinger Bravo ◽  
Hui Jin ◽  
Hyunwoo Park ◽  
Min Sang Kim ◽  
Hirofumi Matsui ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Thrombus Formation ◽  
Umbilical Vein ◽  
Ethanol Extract ◽  
Developed Countries ◽  
Severe Bleeding ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
Angelica Gigas ◽  
Angelica Gigas Nakai

Cardiovascular diseases, such as stroke, are the most common causes of death in developed countries. Ischemic stroke accounts for 85% of the total cases and is caused by abnormal thrombus formation in the vessels, causing deficient blood and oxygen supply to the brain. Prophylactic treatments include the prevention of thrombus formation, of which the most used is acetylsalicylic acid (ASA); however, it is associated with a high incidence of side effects. Angelica gigas Nakai (AG) is a natural herb used to improve blood circulation via anti-platelet aggregation, one of the key processes involved in thrombus formation. We examined the antithrombotic effects of AGE 232, the ethanol extract of A. gigas Nakai. AGE 232 showed a significant reduction in death or paralysis in mice caused by collagen/epinephrine-induced thromboembolism in a dose-dependent manner and inhibition of collagen-induced human platelet aggregation in a concentration-dependent manner. Additionally, AGE 232-treated mice did not show severe bleeding in the gut compared to ASA-treated mice. AGE 232 resulted in a decrease in the number of neutrophils attached to the human umbilical vein endothelial cells (HUVECs) and lower inhibition of COX-1 in response to bleeding and damage to blood vessels, a major side effect of ASA. Therefore, AGE 232 can prevent thrombus formation and stroke.

scholarly journals Current multimodal diagnostic tools for diabetic macular edema to select a management strategy

2021 ◽  
Vol 21 (4) ◽  
pp. 210-214
Author(s):  
M.V. Pshenichnov ◽  
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Management Strategy ◽  
Low Vision ◽  
Management Strategies ◽  
Developed Countries ◽  
Diagnostic Tools ◽  
Published Data ◽  
Working Age ◽  
Diagnostic Approaches

Diabetes is a severe chronic disease that significantly affects the quality of life of individuals, their families, and society worldwide. Diabetic retinopathy, particularly diabetic macular edema (DME), is the leading cause of blindness and low vision among adults of working age in developed countries and Russia. A recent multimodal approach to diagnose DME resulted in new classifications of this disorder and slightly modified earlier views. The analysis of DME biomarkers allows for selecting management strategies for each patient, prescribing adequate medical treatment, and predicting potential treatment response. This paper aimed to analyze published data and up-to-date diagnostic approaches to DME. These tools provide a correct therapeutic strategy based on the DME pattern. Keywords: diabetic macular edema, optical coherence tomography, anti-VEGF treatment. For citation: Pshenichnov M.V. Current multimodal diagnostic tools for diabetic macular edema to select a management strategy. Russian Journal of Clinical Ophthalmology. 2021;21(4):210–214 (in Russ.). DOI: 10.32364/2311-7729-2021-21-4-210-214.

scholarly journals National Service Framework for Mental Health

2000 ◽  
Vol 24 (6) ◽  
pp. 203-206 ◽  
Author(s):  
Graham Thornicroft
Keyword(s):  
Mental Health ◽  
National Service ◽  
Department Of Health ◽  
National Service Framework ◽  
Local Flexibility ◽  
Working Age ◽  
And Performance ◽  
The Given ◽  
Clear Statement ◽  
Service Framework

The National Service Framework for Mental Health (NSF–MH) is a strategic blueprint for services for adults of working age for the next 10 years. It is both mandatory, in being a clear statement of what services must seek to achieve in relation to the given standards and performance indicators, and permissive, in that it allows considerable local flexibility to customise the services which need to be provided to fit the framework. This paper summarises the process by which the NSF was created, and its content, which became clear when it was published on 30 September 1999 (Department of Health, 1999).

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