scholarly journals Multi-membrane search algorithm

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260512
Author(s):  
Qi Song ◽  
Yourui Huang ◽  
Wenhao Lai ◽  
Tao Han ◽  
Shanyong XU ◽  
...  
Keyword(s):  
Pressure Vessel ◽  
High Performance ◽  
Search Algorithm ◽  
Biological Behavior ◽  
Cell Secretion ◽  
Population Number ◽  
Beam Design ◽  
Statistical Experiments ◽  
Comparison Algorithms ◽  
Better Than

This research proposes a new multi-membrane search algorithm (MSA) based on cell biological behavior. Cell secretion protein behavior and cell division and fusion strategy are the main inspirations for the algorithm. In order to verify the performance of the algorithm, we used 19 benchmark functions to compare the MSA test results with MVO, GWO, MFO and ALO. The number of iterations of each algorithm on each benchmark function is 100, the population number is 10, and the running is repeated 50 times, and the average and standard deviation of the results are recorded. Tests show that the MSA is competitive in unimodal benchmark functions and multi-modal benchmark functions, and the results in composite benchmark functions are all superior to MVO, MFO, ALO, and GWO algorithms. This paper also uses MSA to solve two classic engineering problems: welded beam design and pressure vessel design. The result of welded beam design is 1.7252, and the result of pressure vessel design is 5887.7052, which is better than other comparison algorithms. Statistical experiments show that MSA is a high-performance algorithm that is competitive in unimodal and multimodal functions, and its performance in compound functions is significantly better than MVO, MFO, ALO, and GWO algorithms.

scholarly journals Optimal Solution of Structural Engineering Design Problems using Crow Search Algorithm

2019 ◽  
Vol 4 (4) ◽  
pp. 968-981
Author(s):  
Madhur Agarwal
Keyword(s):  
Engineering Design ◽  
Design Problem ◽  
Structural Engineering ◽  
Search Algorithm ◽  
Optimal Solution ◽  
Worst Case ◽  
Design Problems ◽  
Beam Design ◽  
Engineering Design Problems ◽  
Better Than

In real world, the structural engineering design problems are large scale non-linear constrained problems. In the present study, crow search algorithm (CSA) is applied to find the optimal solution of structural engineering design problems such as pressure vessel design problem, welded beam design problem and tension/ compression string design problem. The numerical results are compared with the existing results reported in the literature including metaheuristic algorithms and it is found that the results obtained by the crow search algorithm are better than other existing algorithms. Further, the effectiveness of the algorithm is verified to be better than the existing algorithms by statistical analysis using mean, median, best case, and worst case scenarios. The present study confirms that the crow search algorithm may be easily and effectively applied to various structural design problems.

Advances in imaging SIMS studies of stained and BrdU-labelled human metaphase chromosomes

1995 ◽  
Vol 53 ◽  
pp. 932-933
Author(s):  
R. Levi-Setti ◽  
J. M. Chabala ◽  
R. Espinosa ◽  
M. M. Le Beau
Keyword(s):  
High Performance ◽  
Secondary Ion Mass Spectrometry ◽  
Analytical Sensitivity ◽  
Metaphase Chromosomes ◽  
Banding Patterns ◽  
Sector Mass Spectrometer ◽  
Staining Methods ◽  
The University ◽  
Secondary Ion ◽  
Better Than

We have shown previously that isotope-labelled nucleotides in human metaphase chromosomes can be detected and mapped by imaging secondary ion mass spectrometry (SIMS), using the University of Chicago high resolution scanning ion microprobe (UC SIM). These early studies, conducted with BrdU- and 14C-thymidine-labelled chromosomes via detection of the Br and 28CN- (14C14N-> labelcarrying signals, provided some evidence for the condensation of the label into banding patterns along the chromatids (SIMS bands) reminiscent of the well known Q- and G-bands obtained by conventional staining methods for optical microscopy. The potential of this technique has been greatly enhanced by the recent upgrade of the UC SIM, now coupled to a high performance magnetic sector mass spectrometer in lieu of the previous RF quadrupole mass filter. The high transmission of the new spectrometer improves the SIMS analytical sensitivity of the microprobe better than a hundredfold, overcoming most of the previous imaging limitations resulting from low count statistics.

Evaluation of New 99mTc(CO)3 + Radiolabeled Glycylglycine In Vivo

2019 ◽  
Vol 19 (11) ◽  
pp. 1382-1387
Author(s):  
Ahmet M. Şenışık ◽  
Çiğdem İçhedef ◽  
Ayfer Y. Kılçar ◽  
Eser Uçar ◽  
Kadir Arı ◽  
...  
Keyword(s):  
High Performance ◽  
The Body ◽  
Biological Behavior ◽  
In Vivo Evaluation ◽  
Radiolabeled Peptides ◽  
Tumor Bearing ◽  
Biodistribution Data ◽  
Good Accordance ◽  
Rapid Clearance

Background: Peptide-based agents are used in molecular imaging due to their unique properties, such as rapid clearance from the circulation, high affinity and target selectivity. Many of the radiolabeled peptides have been clinically experienced with diagnostic accuracy. The aim of this study was to investigate in vivo biological behavior of [99mTc(CO)3(H2O)3]+ radiolabeled glycylglycine (GlyGly). Methods: Glycylglycine was radiolabeled with a high radiolabeling yield of 94.69±2%, and quality control of the radiolabeling process was performed by thin layer radiochromatography (TLRC) and High-Performance Liquid Radiochromatography (HPLRC). Lipophilicity study for radiolabeled complex (99mTc(CO)3-Gly-Gly) was carried out using solvent extraction. The in vivo evaluation was performed by both biodistribution and SPECT imaging. Results: The high radiolabelling yield of 99mTc(CO)3-GlyGly was obtained and verified by TLRC and HPLRC as well. According to the in vivo results, SPECT images and biodistribution data are in good accordance. The excretion route from the body was both hepatobiliary and renal. Conclusion: This study shows that 99mTc(CO)3-GlyGly has the potential to be used as a peptide-based imaging agent. Further studies, 99mTc(CO)3-GlyGly can be performed on tumor-bearing animals.

scholarly journals Binary Spring Search Algorithm for Solving Various Optimization Problems

2021 ◽  
Vol 11 (3) ◽  
pp. 1286 ◽  
Author(s):  
Mohammad Dehghani ◽  
Zeinab Montazeri ◽  
Ali Dehghani ◽  
Om P. Malik ◽  
Ruben Morales-Menendez ◽  
...  
Keyword(s):  
Optimization Algorithm ◽  
High Performance ◽  
Optimization Problems ◽  
Search Algorithm ◽  
Gravitational Search Algorithm ◽  
Bat Algorithm ◽  
Search Space ◽  
Binary Particle Swarm Optimization ◽  
Dragonfly Algorithm ◽  
Grasshopper Optimization Algorithm

One of the most powerful tools for solving optimization problems is optimization algorithms (inspired by nature) based on populations. These algorithms provide a solution to a problem by randomly searching in the search space. The design’s central idea is derived from various natural phenomena, the behavior and living conditions of living organisms, laws of physics, etc. A new population-based optimization algorithm called the Binary Spring Search Algorithm (BSSA) is introduced to solve optimization problems. BSSA is an algorithm based on a simulation of the famous Hooke’s law (physics) for the traditional weights and springs system. In this proposal, the population comprises weights that are connected by unique springs. The mathematical modeling of the proposed algorithm is presented to be used to achieve solutions to optimization problems. The results were thoroughly validated in different unimodal and multimodal functions; additionally, the BSSA was compared with high-performance algorithms: binary grasshopper optimization algorithm, binary dragonfly algorithm, binary bat algorithm, binary gravitational search algorithm, binary particle swarm optimization, and binary genetic algorithm. The results show the superiority of the BSSA. The results of the Friedman test corroborate that the BSSA is more competitive.

scholarly journals Performance of Seven Consumer Sleep-Tracking Devices Compared with Polysomnography

SLEEP ◽  
2020 ◽  
Author(s):  
Evan D Chinoy ◽  
Joseph A Cuellar ◽  
Kirbie E Huwa ◽  
Jason T Jameson ◽  
Catherine H Watson ◽  
...  
Keyword(s):  
Performance Measures ◽  
Gold Standard ◽  
High Performance ◽  
Sleep Stage ◽  
Sleep Laboratory ◽  
Sleep Assessment ◽  
Sleep Condition ◽  
Different Populations ◽  
Tracking Devices ◽  
Better Than

Abstract Study Objectives Consumer sleep-tracking devices are widely used and becoming more technologically advanced, creating strong interest from researchers and clinicians for their possible use as alternatives to standard actigraphy. We therefore tested the performance of many of the latest consumer sleep-tracking devices, alongside actigraphy, versus the gold-standard sleep assessment technique, polysomnography (PSG). Methods In total, 34 healthy young adults (22 women; 28.1 ± 3.9 years, mean ± SD) were tested on three consecutive nights (including a disrupted sleep condition) in a sleep laboratory with PSG, along with actigraphy (Philips Respironics Actiwatch 2) and a subset of consumer sleep-tracking devices. Altogether, four wearable (Fatigue Science Readiband, Fitbit Alta HR, Garmin Fenix 5S, Garmin Vivosmart 3) and three non-wearable (EarlySense Live, ResMed S+, SleepScore Max) devices were tested. Sleep/wake summary and epoch-by-epoch agreement measures were compared with PSG. Results Most devices (Fatigue Science Readiband, Fitbit Alta HR, EarlySense Live, ResMed S+, SleepScore Max) performed as well as or better than actigraphy on sleep/wake performance measures, while the Garmin devices performed worse. Overall, epoch-by-epoch sensitivity was high (all ≥0.93), specificity was low-to-medium (0.18-0.54), sleep stage comparisons were mixed, and devices tended to perform worse on nights with poorer/disrupted sleep. Conclusions Consumer sleep-tracking devices exhibited high performance in detecting sleep, and most performed equivalent to (or better than) actigraphy in detecting wake. Device sleep stage assessments were inconsistent. Findings indicate that many newer sleep-tracking devices demonstrate promising performance for tracking sleep and wake. Devices should be tested in different populations and settings to further examine their wider validity and utility.

scholarly journals A high-fidelity realization of the Euclid code comparison N-body simulation with Abacus

2019 ◽  
Vol 485 (3) ◽  
pp. 3370-3377 ◽  
Author(s):  
Lehman H Garrison ◽  
Daniel J Eisenstein ◽  
Philip A Pinto
Keyword(s):  
Power Spectrum ◽  
High Performance ◽  
High Fidelity ◽  
Step Size ◽  
Time Step ◽  
Code Comparison ◽  
Force Accuracy ◽  
Integration Errors ◽  
Better Than ◽  
Good Agreement

Abstract We present a high-fidelity realization of the cosmological N-body simulation from the Schneider et al. code comparison project. The simulation was performed with our AbacusN-body code, which offers high-force accuracy, high performance, and minimal particle integration errors. The simulation consists of 20483 particles in a $500\ h^{-1}\, \mathrm{Mpc}$ box for a particle mass of $1.2\times 10^9\ h^{-1}\, \mathrm{M}_\odot$ with $10\ h^{-1}\, \mathrm{kpc}$ spline softening. Abacus executed 1052 global time-steps to z = 0 in 107 h on one dual-Xeon, dual-GPU node, for a mean rate of 23 million particles per second per step. We find Abacus is in good agreement with Ramses and Pkdgrav3 and less so with Gadget3. We validate our choice of time-step by halving the step size and find sub-percent differences in the power spectrum and 2PCF at nearly all measured scales, with ${\lt }0.3{{\ \rm per\ cent}}$ errors at $k\lt 10\ \mathrm{Mpc}^{-1}\, h$. On large scales, Abacus reproduces linear theory better than 0.01 per cent. Simulation snapshots are available at http://nbody.rc.fas.harvard.edu/public/S2016.

Copper Ulsi Interconnect Technology

1998 ◽  
Vol 514 ◽  
Author(s):  
D. Edelstein
Keyword(s):  
High Performance ◽  
Stress Testing ◽  
Cmos Technology ◽  
Functional Verification ◽  
Functional Modules ◽  
Mos Devices ◽  
Potential Problems ◽  
Cu Contamination ◽  
Interconnect Technology ◽  
Better Than

ABSTRACTRecently IBM announced the first implementation of full copper ULSI wiring in a CMOS technology, to be manufactured on its high-performance 0.22 um CMOS products this year. Features of this technology will be presented, as well as functional verification on CMOS chips. To reach this level, extensive yield, reliability, and stress testing had to be done on test and product-like chips, including those packaged into product modules. Data will be presented fom all aspects of this testing, ranging from experiments designed to promote Cu contamination of the MOS devices, to temperature/humidity/bias stressing of assembled functional modules. The results in all areas are shown to be equal to or better than standards set by our current AI(Cu)/Wstud technology. This demonstrates that the potential problems associated with copper wiring that have long been discussed can be overcome.

scholarly journals PHEMTO: the polarimetric high energy modular telescope observatory

2021 ◽  
Author(s):  
P. Laurent ◽  
F. Acero ◽  
V. Beckmann ◽  
S. Brandt ◽  
F. Cangemi ◽  
...  
Keyword(s):  
Black Holes ◽  
Energy Range ◽  
High Performance ◽  
Angular Resolution ◽  
High Energy ◽  
Thermal Processes ◽  
Scientific Performance ◽  
X Ray ◽  
Measurement Capability ◽  
Better Than

AbstractBased upon dual focusing techniques, the Polarimetric High-Energy Modular Telescope Observatory (PHEMTO) is designed to have performance several orders of magnitude better than the present hard X-ray instruments, in the 1–600 keV energy range. This, together with its angular resolution of around one arcsecond, and its sensitive polarimetry measurement capability, will give PHEMTO the improvements in scientific performance needed for a mission in the 2050 era in order to study AGN, galactic black holes, neutrons stars, and supernovae. In addition, its high performance will enable the study of the non-thermal processes in galaxy clusters with an unprecedented accuracy.

Process optimization of chili flavor beef tallow and analysis of its volatile compounds by GC-IMS

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hang Li ◽  
Jiamin Liu ◽  
Zhanzhong Wang ◽  
Xiaodong Liu ◽  
Xichun Yan ◽  
...  
Keyword(s):  
Volatile Compounds ◽  
Ion Mobility ◽  
Beef Tallow ◽  
High Performance ◽  
Raw Materials ◽  
Chromatic Aberration ◽  
Frying Temperature ◽  
Frying Time ◽  
Solid Liquid ◽  
Better Than

Abstract With chili and liquid beef tallow as the main raw materials, the processing conditions of chili flavor beef tallow were explored. Gas chromatograpy-ion mobility spectrometry (GC-IMS) was used to determine the volatile compounds in chili flavor beef tallow. The capsaicin and dihydrocapsaicin in chili flavor beef tallow were determined by high performance liquid chromatography (HPLC). The optimum technological conditions were determined, and the index of chromatic aberration, cholesterol was also determined. Based on GC-IMS analysis, 102 kinds of volatile compounds were detected, and the sample III (the ratio of solid–liquid was 1:5, the frying temperature was 120 °C, and the frying time was 15 min) performed better than other samples. The preparation of chili beef tallow improves its antioxidant activity and makes its aroma more intense and more in line with the taste of Chinese people, which provides a theoretical and practical basis for the development of spice beef tallow in the future.

How significant are the known collision and element distinctness quantum algorithms?

2004 ◽  
Vol 4 (3) ◽  
pp. 201-206
Author(s):  
L. Grover ◽  
T. Rudolph
Keyword(s):  
Search Algorithm ◽  
Quantum Algorithms ◽  
Search Space ◽  
Space Complexity ◽  
Quantum Search ◽  
Quantum Search Algorithm ◽  
Time Space ◽  
Simple Quantum ◽  
Structured Problems ◽  
Better Than

Quantum search is a technique for searching $N$ possibilities for a desired target in $O(\sqrt{N})$ steps. It has been applied in the design of quantum algorithms for several structured problems. Many of these algorithms require significant amount of quantum hardware. In this paper we propose the criterion that an algorithm which requires $O(S)$ hardware should be considered significant if it produces a speedup of better than $O\left(\sqrt{S}\right)$ over a simple quantum search algorithm. This is because a speedup of $O\left(\sqrt{S}\right)$ can be trivially obtained by dividing the search space into $S$ separate parts and handing the problem to $S$ independent processors that do a quantum search (in this paper we drop all logarithmic factors when discussing time/space complexity). Known algorithms for collision and element distinctness exactly saturate the criterion.

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