The Relationship Between Birthweight Discordance and Perinatal Mortality of One of the Twins in a Twin Pair

2006 ◽  
Vol 9 (2) ◽  
pp. 292-297 ◽  
Author(s):  
Noriko Kato ◽  
Tomohiro Matsuda
Keyword(s):  
Birth Weight ◽  
Perinatal Mortality ◽  
Low Birthweight ◽  
Twin Pair ◽  
Population Based ◽  
Cumulative Frequency ◽  
Live Births ◽  
Using Data ◽  
Lower Birthweight ◽  
The Relationship

AbstractThis study aimed to evaluate the prevalence of birth-weight discordance among twins, to determine the risk cut-off point for birthweight discordance, and to clarify whether perinatal deaths are aggravated by birthweight discordance or by low birthweight itself. A population-based analysis of all twins born between 1995 and 1999 in Japan was conducted using data collected from national birth, death and stillbirth certificates. Birthweight discordance was determined as: higher birthweight minus lower birthweight divided by higher birthweight multiplied by 100. Among twins with a birthweight discordance of more than 15%, the fetal and perinatal mortality rate was higher than that of twins with a discordance of less than 15%. Ninety per cent of the relative cumulative frequency of twin live-births were within 25% of the birthweight discordance. Logistic regression analysis showed that the stillbirth of at least one of the twins is associated with the birthweight of the larger twin and birthweight discordance. It also showed that the stillbirth of both twins in the twin pair is associated with the birth-weight of larger twins and the gestational weeks. It was clarified that birthweight discordance was associated with the stillbirth of only one twin in the twin pair, and the stillbirth of both twins in the twin pair was associated with low birthweight itself.

scholarly journals Biodemographic Analysis of Factors Related to Perinatal Mortality in Portugal (1988–2011)

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Vicente Fuster
Keyword(s):  
Birth Weight ◽  
Neonatal Mortality ◽  
Perinatal Mortality ◽  
Minimum Duration ◽  
Mortality Risks ◽  
Live Births ◽  
Early Neonatal Mortality ◽  
Logistic Regressions ◽  
The Relationship ◽  
Duration Of Gestation

Background. The purpose of this paper is to determine the relative mortality risks at delivery and during the first week of life with regard to maternal and foetal characteristics.Methods. Yearly individual digital records on live births and early neonatal mortality were used to infer the possible factors involved in perinatal deaths.Results. The results show that the number of births per year declined with time throughout the period studied. At the same time, rates decreased in 66.4% for stillbirths and in 70.2% for early neonatal mortality. Logistic regressions modelled the interaction of the two mortality indicators and covariables such as birth weight and the duration of gestation.Conclusions. This research provides a first biodemographic approach to the knowledge of factors influencing perinatal mortality in Portugal based on a set of foetal and maternal variables. Although the magnitude of the different perinatal mortality rates may be affected by the criteria used for selecting cases (multiple-singletons; minimum birth weight or minimum duration of gestation), one of the conclusions of the present analysis is that the relationship among the maternal and foetal variables that determine the relative risk remains unaltered. Certain resemblance with the factors determining negative birth outcomes in Spain is appreciated.

Birthweight and Adult Health in a Population-Based Sample of Norwegian Twins

2005 ◽  
Vol 8 (2) ◽  
pp. 148-155 ◽  
Author(s):  
Andrej M. Grjibovski ◽  
Jennifer R. Harris ◽  
Per Magnus
Keyword(s):  
Health Outcomes ◽  
Population Based ◽  
Adult Health ◽  
Brain Disorder ◽  
Full Sample ◽  
Intraclass Correlations ◽  
Opposite Sex ◽  
Lower Birthweight ◽  
The Relationship ◽  
Pair Analysis

AbstractPopulation-based twin data were used to test (a) whether lower birthweight confers a greater risk of adult health disorders, and (b) whether within-pair birthweight differences in twins explain discordance for health outcomes. The sample consisted of 1201 monozygotic (MZ) male twins, 1048 dizygotic (DZ) male twins, 1679 MZ female twins, 1489 DZ female twins, and 2423 opposite-sex DZ twins, born in Norway between 1967 and 1979. The relationship between birthweight and self-reported health outcomes were studied using multivariable logistic regression. In the full sample (n= 7840), birthweight was negatively associated with risk for nearsightedness (odds ratio OR = 0.76, 95% CI: 0.65 – 0.92) and minimal brain disorder (OR = 0.27, 95% CI: 0.16–0.44) when adjusted for gestational age, sex, zygosity, age, education and body mass index after correction for intraclass correlations and multiple comparisons. Within-pair analysis of 159 MZ and 224 DZ pairs revealed that myopic twins were on average 2 g (p= .966) and 64 g (p= .040) lighter than nonmyopic twins in MZ and DZ pairs respectively, suggesting that genetic factors may play an important role in the associations between birthweight and nearsightedness. Within-pair analysis of twins discordant for a minimal brain disorder indicated that affected twins were 80 g (p= .655) and 85 g (p= .655) lighter than their healthy co-twins in MZ and DZ pairs respectively, although there were only 2 MZ and 2 DZ discordant pairs.

Analysis of selected perinatological indicators in the Slovak Republic in the years 2007–2018

2021 ◽  
Vol 86 (2) ◽  
pp. 102-109
Author(s):  
Miroslav Korbeľ ◽  
◽  
Pavel Kaščák ◽  
zuzana Nižňanská
Keyword(s):  
Birth Weight ◽  
Mortality Rate ◽  
Low Birth Weight ◽  
Perinatal Mortality ◽  
Total Fertility Rate ◽  
Very Low Birth Weight ◽  
Slovak Republic ◽  
In Utero ◽  
Fertility Rate ◽  
Live Births

Overview Objective: Analysis of perinatal mortality in the Slovak Republic during the years 2007–2018. Methods: Analysis of prospectively collected selected perinatal data in the years 2007–2018. Results: In the year 2007, there were 63 obstetrics units, 51,146 deliveries and that of live births 51,650 in the Slovak Republic. The number of obstetrics units decreased to 51 in the years 2018, the total number of deliveries increased to 57,085 and that of live births increased to 57,773. The total fertility rate in the years 2007–2018 increased from 1.27 to 1.54. The preterm deliveries rate increased from 7.3% in the year 2007 to 8.5% in the year 2010 and decreased to 7% in the year 2018. The perinatal mortality rate decreased from 6.2 in the year 2007 to 4.4 in the year 2017, increased again in the years 2018 to 5.0 and according to the criteria of WHO (World Health Organization) to 6.6 per 1,000 still- and live-births. During the years 2007–2018 at perinatal mortality stillbirth participate with 65%, low birth weight with 63% and severe congenital anomalies with 19%. Transport in utero to perinatological centers in the years 2007–2018 has decreased from 57 to 56% for infants 1,000–1,499 g and from 75 to 73% for infants below 1,000 g. Conclusion: In the year 2017, perinatology in the Slovak Republic reached the best result in the perinatal mortality rate – 4.4‰ (0.44%), but has increased to over 5‰ next year. To further reduce perinatal mortality in the Slovak Republic, it is necessary to improve the prenatal dia­gnosis of severe congenital abnormalities, transport in utero of very low birth weight fetuses, centralization of high-risk pregnancies, obstetric personnel and material-technical equipment of obstetricians and neonatal intensive care units. Keywords: perinatal mortality – preterm delivery – multiple pregnancy – low birth weight – very low birth weight – total fertility rate

Socioeconomic Status and Orofacial Clefts in Scotland, 1989 to 1998

2003 ◽  
Vol 40 (5) ◽  
pp. 481-485 ◽  
Author(s):  
J. D. Clark ◽  
P. A. Mossey ◽  
L. Sharp ◽  
J. Little
Keyword(s):  
Risk Factors ◽  
Socioeconomic Status ◽  
Cleft Lip ◽  
Population Based ◽  
Orofacial Clefts ◽  
Smoking During Pregnancy ◽  
Live Births ◽  
Strong Positive Relationship ◽  
The Relationship ◽  
Deprived Areas

Objective The purpose of this study was to investigate the association between socioeconomic status and orofacial clefts (OFC) in Scotland. Design Study of prevalence at birth over a 10-year period using an area-based measure of material deprivation. Setting Population-based study throughout Scotland. Participants Eight hundred thirty-four live births with OFC born between January 1, 1989, and December 31, 1998, ascertained from the nationwide register of the Cleft Service in Scotland, compared with the total 603,825 live births in Scotland in this period. Results There was a strong positive relationship whereby the prevalence of OFC at birth increased with increasing deprivation. This trend was statistically significant for cleft lip and/or palate (CL[P]: p = .016) but not for cleft palate (CP; p = .078). For each type of cleft, the relative risk among those resident in the most deprived areas, compared with those resident in the least deprived areas, was 2.33. Conclusions The association between OFC and socioeconomic status is consistent with a report for an earlier period in a smaller part of Scotland. Unlike the earlier study, this pattern appears to be stronger for CL(P) than for CP. These observations do not appear to be an artifact of recording. It is possible that they reflect the association between deprivation and risk factors for OFC, most likely tobacco smoking during pregnancy. Because the relationship between OFC and socioeconomic status appears to have been virtually unstudied in other populations, it would be valuable to investigate this relationship elsewhere and determine whether known risk factors account for the relationship.

scholarly journals Comparing regional neonatal mortality rates: the influence of registration of births as live born for birth weight <500 g in Taiwan

2019 ◽  
Vol 3 (1) ◽  
pp. e000526
Author(s):  
Liang-Yi Wang ◽  
Yu-Shan Chang ◽  
Fu-Wen Liang ◽  
Yung-Chieh Lin ◽  
Yuh-Jyh Lin ◽  
...  
Keyword(s):  
Birth Weight ◽  
Neonatal Mortality ◽  
Ecological Study ◽  
Population Based ◽  
Cross Sectional ◽  
Neonatal Deaths ◽  
Live Births ◽  
Taipei City ◽  
The Impact ◽  
The City

ObjectiveTo investigate regional variation in the registration of births (still+live) as live born for birth weight <500 g and the impact on the city/county ranking of neonatal mortality rate (NMR) in Taiwan.DesignPopulation-based cross-sectional ecological study.Setting20 cities/counties in Taiwan.ParticipantsRegistered births for birth weight <500 g and neonatal deaths in 2015–2016.Main outcome measuresCity/county percentage of births <500 g registered as live born and ranking of city/county NMR (deaths per 1000 live births) including and excluding live births <500 g.ResultsThe percentage of births <500 g registered as live born ranged from 0% in Keelung City (0/26) and Penghu County (0/4) to 20% in Taipei City (112/558), 24% in Hsinchu County (5/21) and 28% in Hualien County (9/32). The change in city/county ranking of NMR from including to excluding live births <500 g was most prominent in Taipei City (from the 15th to the 1st) followed by Kaohsiung City (from the 18th to the 14th).ConclusionsThe city/county NMR in Taiwan is influenced by variation in the registration of live born for births with uncertain viability. We recommend presenting city/county NMR using both criteria (with or without minimum threshold of gestation period or birth weight) for better interpretation of the findings of comparisons of city/county NMR.

scholarly journals Neonatal and perinatal mortality trend among 23,000 babies delivered during three years at an urban university teaching hospital of Nepal

2019 ◽  
Vol 6 (2) ◽  
pp. 90-95
Author(s):  
Rateena Rajbhandari ◽  
Puja Amatya ◽  
Shova Shrestha
Keyword(s):  
Birth Weight ◽  
Mortality Rate ◽  
Perinatal Mortality ◽  
Mode Of Delivery ◽  
Final Outcome ◽  
University Teaching ◽  
Microsoft Excel ◽  
Live Births ◽  
Perinatal Audit ◽  
Urban University

Introductions: Perinatal mortality rate (PMR) of Nepal is 31 deaths per 1000 pregnancies and neonatal mortality rate (NMR) is 21 deaths per 1000 live births according to Nepal Demographic and Health Survey (NDHS) 2016. This study aims to analyse the trend of PMR and NMR of babies delivered at Patan hospital, Nepal. Methods: This was a retrospective study done in the department of Pediatrics to analyse the trend of neonatal and perinatal outcome of babies delivered during three years from April 2016 to March 2019 at Patan Hospital, Patan Academy of Health Sciences, Nepal. Data was collected from hospital records and perinatal audit. The mode of delivery (vaginal, instrumental, caesarian), birth status (sex, premature, still, live, APGAR, birth weight) and final outcome (neonatal and perinatal mortalities) were analyzed descriptively using Microsoft Excel 2010. Results: The final outcome of total 22937 deliveries during three years were PMR 4.34, corrected PMR 10.85 per 1000 total births and NMR 3.62 per 1000 live births. There were 22913 (99%) live births, 3090 (13.3%) had low birth weight, 11898 (52%) spontaneous vaginal delivery, 10700 (47%) cesarean and 339 (1.5%) instrumental deliveries. Conclusions: The overall PMR was 4.34 per 1000 total births and NMR was 3.62 per 1000 live births at Patan Hospital.

Both low birthweight and high birthweight are associated with cognitive impairment in persons with schizophrenia and their first-degree relatives

2013 ◽  
Vol 43 (11) ◽  
pp. 2361-2367 ◽  
Author(s):  
M. Torniainen ◽  
A. Wegelius ◽  
A. Tuulio-Henriksson ◽  
J. Lönnqvist ◽  
J. Suvisaari
Keyword(s):  
Low Birthweight ◽  
Neuropsychological Test ◽  
Estimating Equation ◽  
Population Based ◽  
Continuous Variable ◽  
First Degree Relatives ◽  
Increased Risk ◽  
Axis I ◽  
Persons With Schizophrenia ◽  
The Relationship

BackgroundBoth low birthweight and high birthweight have been associated with an increased risk for schizophrenia and cognitive impairments in the general population. We assessed the association between birthweight and cognitive performance in persons with schizophrenia and their unaffected first-degree relatives.MethodWe investigated a population-based family sample comprising persons with schizophrenia (n = 142) and their unaffected first-degree relatives (n = 277). Both patients and relatives were interviewed with the Structured Clinical Interview for DSM-IV Axis I Disorders, Clinician Version (SCID-CV) and a comprehensive neuropsychological test battery was administered. Information on birthweight was obtained from obstetric records. We used generalized estimating equation (GEE) models to investigate the effect of birthweight, as a continuous variable, on cognitive functioning, adjusting for within-family correlation and relevant covariates.ResultsBoth low birthweight and high birthweight were associated with lower performance in visuospatial reasoning, processing speed, set-shifting and verbal and visual working memory among persons with schizophrenia and their unaffected first-degree relatives compared to individuals with birthweight in the intermediate range. The group × birthweight interactions were non-significant.ConclusionsBoth low birthweight and high birthweight are associated with deficits in cognition later in life. Schizophrenia does not seem to modify the relationship between birthweight and cognition in families with schizophrenia.

scholarly journals Fatores associados ao baixo peso ao nascer em crianças do Rio Grande do Sul

2020 ◽  
Vol 42 ◽  
pp. e43
Author(s):  
Angelica Peripolli ◽  
Anaelena Bragança de Moraes ◽  
Luciane Flores Jacobi ◽  
Roselaine Ruviaro Zanini
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Strong Association ◽  
Significant Risk ◽  
Rio Grande ◽  
Vulnerable Groups ◽  
Protective Effects ◽  
Rio Grande Do Sul ◽  
Live Births ◽  
Using Data

In this study were identified and quantified the risk factors associated to live births with low birth weight in Rio Grande do Sul, in 2011 using data from the Information System on Live Births. The prevalence of low birth weight (LBW) was 8.1%. By adjusting logistic regression, two models were proposed. For the first one, the predictors significant risk variables at 5% were: mothers aged 35 or more; nulliparous; with elementary school II or high school; legally separated or divorced; mothers who did not receive prenatal care; birth that occurred outside the hospital; prematurity; female and who had congenital anomaly. The protective effects variables were teenage mothers and who did not work outside the home. The type of delivery was included in the second model proposed, which was more appropriate to estimate the probability of a live birth born underweight. It was possible to conclude that it is important to consider effective actions to vulnerable groups aiming to reduce LBW rates, examining the strong association with infant mortality rates.

scholarly journals Prematurity and Body Fat at 6, 18, and 30 Years of Age: Pelotas (Brazil) 2004, 1993, and 1982 Birth Cohorts

2020 ◽  
Author(s):  
Caroline Cardozo Bortolotto ◽  
Iná Santos ◽  
Juliana dos Santos Vaz ◽  
Alicia Matijasevich ◽  
Aluísio J.D. B ◽  
...  
Keyword(s):  
Body Fat ◽  
Fat Mass ◽  
Population Based ◽  
Z Score ◽  
Birth Cohorts ◽  
Air Displacement Plethysmography ◽  
Live Births ◽  
Using Data ◽  
The City ◽  
Prevention Of Prematurity

Abstract Background: Our aim was to investigate the association between preterm birth and body fat at 6, 18, and 30 years of age using data from three population-based birth cohort studies. Methods: Information on gestational age (GA) gathered in the hospital of birth in the first 24-hours after the delivery was obtained for all live births occurring in the city of Pelotas, Brazil, in the years 2004, 1993 and 1982. GA was defined by the date of last menstrual period and was later categorized in ≤33, 34-36 and ≥37 weeks. Body fat was assessed by air-displacement plethysmography. Outcomes included fat mass (FM, kg), percent fat mass (%FM), fat mass index (FMI, kg/m2), and body mass index (BMI, kg/m2 at 18 years in the 1993 cohort and at 30 years in the 1982 cohort; and BMI Z-score, at 6 years in the 2004 cohort). Crude and adjusted linear regression provided beta coefficients with 95% confidence intervals (95%CI).Results: A total of 3036, 3027, and 2417 participants, respectively, from the 2004, 1993, and 1982 cohorts were analyzed. At 6 years, boys born at 34-36 weeks GA presented lower adjusted mean %FM (β: -2.91%; -4.45--1.36), FMI (β: -0.70 kg/m2 ; -1.13--0.28) and BMI Z-score (β: -0.48 kg/m2; -0.79--0.16), when compared to boys born at term (≥37). At 30 years, FM (15.6kg; 0.40-30.90), %FM (13.65%; 1.38-25.92) and FMI (5.3kg/m2; 0.30-10.37) were higher among males born at ≤33 weeks, with no statistical difference as compared to those born at term. No association was found between GA and body fat at the 1993 cohort (18 years) for both sexes. Conclusions: Given the large number of preterm infants born each year, prevention of prematurity is essential as there are possible links between body composition and diseases later in life.

scholarly journals 1014Maternal educational qualification and child’s birth weight: Findings from Office for National Statistics Longitudinal Study

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Jitka Pikhartova ◽  
Rachel Stuchbury ◽  
Nicola Shelton
Keyword(s):  
Longitudinal Study ◽  
Birth Weight ◽  
Maternal Education ◽  
Low Birthweight ◽  
Later Life ◽  
National Statistics ◽  
Partnership Status ◽  
Education Degree ◽  
Low Levels ◽  
Lower Birthweight

Abstract Background Lower maternal education was found to be associated with lower child’s birthweight which in turn was a possible risk factor for later poor health. Presented research aims to assess the association between maternal education and singleton’s birthweight in large UK data, accounting for characteristics such child’s gender, parity, maternal age, partnership status, ethnicity, and household socioeconomic characteristics. Methods Using England and Wales Office for National Statistics Longitudinal Study (ONS-LS), data from over 240,000 children born since 1981 to ONS-LS sample mothers were used. Maternal education was derived into 3 categories (below secondary, complete secondary education, degree and higher). Results Crude analysis confirmed significant association between the level of education and birthweight in each Census cohort (p &lt; 0.001). In adjusted models, the education gradient was partly explained but remained strongly significant, and substantially increased over the years: for example, the birthweight difference between those with below secondary educated mothers and those with degree increased from 29 to 92 grams (p for change&lt;0.001). Conclusions Our findings support previous evidence using different, usually smaller, population samples. Children of mothers with no or low qualification are more prone to be born with lower birthweight leading potentially into health disadvantages in their later life. Our results suggest that the inequalities in birth weight increased over the last 35 years. Key messages Low levels of maternal education predicts low birthweight in children.

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