scholarly journals Periodontal Disease in Medically Compromised Patients and Its Relation with Covid-19

2021 ◽  
Vol 10 (20) ◽  
pp. 1558-1560
Author(s):  
Gowri Swaminatham Pendyala ◽  
Pradeep Kumar ◽  
Sourabh Ramesh Joshi ◽  
Sonia Godara ◽  
Shridhar Shetty
Keyword(s):  
Periodontal Disease ◽  
Alveolar Bone ◽  
Kidney Diseases ◽  
Periodontal Diseases ◽  
Respiratory Illness ◽  
Viral Disease ◽  
Oral Health Status ◽  
Comorbid Conditions ◽  
And Gender ◽  
Compromised Patients

Periodontal diseases can have systemic effects on our body. Diabetes, cardiovascular disease, hypertension etc., have a history of being associated with periodontal disease. Periodontal disease could indicate the severity of Covid-19. There has been no previous reporting of oral health status in Covid-19 patients. The knowledge of association of periodontal disease with severe Covid-19 could be an important contribution to slowing down the rate and spread of infection. Periodontal disease is an inflammatory disease which involves gingiva and the supporting tissues like cementum, alveolar bone and periodontal ligament. It has affected nearly about 10 - 12 % of the total population in the world. Periodontal disease is more prevalent in medically compromised patients with diseases like asthma, diabetes, hypertension, cardiovascular diseases, liver diseases, kidney diseases and rheumatoid arthritis. The other risk factors for the occurrence of periodontal disease are tobacco smoking, ageing, poor oral hygiene, obesity etc.1 Coronavirus (CoV) belongs to Coronaviridae family which are RNA viruses. Their size varies from 60 - 140 nanometre with spike-like projections on its surface. This strain of viruses is considered to be zoonotic in nature and cause respiratory illness in humans.1 This viral disease has affected lakhs of people in United States and had resulted in a high mortality rate. It was declared a pandemic by WHO on the 11th of March 2020. Comorbid conditions such as diabetes, hypertension, asthma, ageing, obesity and gender pose a greater risk for Covid-19. We wanted to evaluate as to whether periodontal disease along with comorbid conditions share a contributing risk factor for developing Covid-19.

scholarly journals Age and oral health: current considerations

2007 ◽  
Vol 21 (spe) ◽  
pp. 29-33 ◽  
Author(s):  
Andrew Tawse-Smith
Keyword(s):  
Risk Factors ◽  
Periodontal Disease ◽  
Dental Plaque ◽  
Alveolar Bone ◽  
Periodontal Diseases ◽  
The Elderly ◽  
Preventive Program ◽  
Age Related ◽  
The Individual ◽  
Complex Scenario

Dental plaque is still considered the main etiological factor for periodontal diseases. Our understanding of periodontal disease has advanced from the previous concepts where gingivitis slowly progressed to periodontitis to a more complex scenario that correlates several risk factors in the pathogenesis of periodontal disease. Among these factors, age has been associated with increased rates of periodontal disease as the population gets older. Although the loss of alveolar bone and periodontal attachment is common in the elderly population, and there is evident age-related changes in the periodontium, severe periodontitis is not a natural consequence of ageing. The importance of identifying the risk factors that participate in the pathogenesis of periodontal disease at an early phase, both of the individual and the disease, as well as evaluating the capacity of the individual to control dental plaque will enable the implementation of an adequate preventive program, where the needs and limitations of the individual are considered to specifically tailor the oral hygiene procedures and the mouthwashes to be used.

scholarly journals A Diet Rich in Saturated Fat and Cholesterol Aggravates the Effect of Bacterial Lipopolysaccharide on Alveolar Bone Loss in a Rabbit Model of Periodontal Disease

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1405
Author(s):  
Alfonso Varela-López ◽  
Pedro Bullón ◽  
César L. Ramírez-Tortosa ◽  
María D. Navarro-Hortal ◽  
María Robles-Almazán ◽  
...  
Keyword(s):  
Bone Loss ◽  
Periodontal Disease ◽  
Dietary Habits ◽  
Alveolar Bone ◽  
Periodontal Diseases ◽  
Rabbit Model ◽  
Saturated Fat ◽  
Alveolar Bone Loss ◽  
Standard Diet ◽  
Alcoholic Fatty Liver

Increasing evidence connects periodontitis with a variety of systemic diseases, including metabolic syndrome, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD). The proposal of this study was to evaluate the role of diets rich in saturated fat and cholesterol in some aspects of periodontal diseases in a lipopolysaccharide (LPS)-induced model of periodontal disease in rabbits and to assess the influence of a periodontal intervention on hyperlipidemia, atherosclerosis, and NAFLD progression to non-alcoholic steatohepatitis. Male rabbits were maintained on a commercial standard diet or a diet rich in saturated fat (3% lard w/w) and cholesterol (1.3% w/w) (HFD) for 40 days. Half of the rabbits on each diet were treated 2 days per week with intragingival injections of LPS from Porphyromonas gingivalis. Morphometric analyses revealed that LPS induced higher alveolar bone loss (ABL) around the first premolar in animals receiving standard diets, which was exacerbated by the HFD diet. A higher score of acinar inflammation in the liver and higher blood levels of triglycerides and phospholipids were found in HFD-fed rabbits receiving LPS. These results suggest that certain dietary habits can exacerbate some aspects of periodontitis and that bad periodontal health can contribute to dyslipidemia and promote NAFLD progression, but only under certain conditions.

scholarly journals Periodontal and chronic kidney diseases: A modifiable association

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Foujan Jabbarzadehkhoei ◽  
Soheila Bakhshandeh ◽  
Mahshid Namdari ◽  
Mina Pakkhesal ◽  
Mohammad Hossein Khoshnevisan
Keyword(s):  
Health Status ◽  
Oral Health ◽  
Kidney Diseases ◽  
Periodontal Diseases ◽  
Treatment Protocol ◽  
Oral Health Status ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Cross Sectional ◽  
Periodontal Index

Objectives: The purpose of this study was to assess the relationship between periodontal diseases and CKD duration. Methods: This descriptive cross-sectional study was conducted on referral CKD patients to a teaching hospital in 2017. Two instruments were used for data collection. The first one was a self-reported questionnaire regarding oral health status and patients’ behaviors. The second questionnaire was used for the clinical assessment of oral health status. Results: Out of 192 patients, 46.9% were male and 53.1% female with a mean (SD) age of 51.9 (±15.1) years. The mean duration of CKD was 7.70 (±7.34) years. About 67.7% of patients experienced toothache in the past year. Also, 67.7% had gingival bleeding (BOP), 34.4% had Clinical Attachment Loss (CAL) > 4 mm, and over 50% of patients had a pocket depth (PD) > 4 mm. By controlling the patient’s age, a direct correlation was detected between the duration of CKD and DMFT index (r=0.64, P<0.001). Moreover, the prolongation of the disease period was detected in patients with CAL>4 mm (P=0.02). Likewise, a direct correlation was detected between the duration of CKD and the periodontal index (r=0.48, P<0.001). Conclusion: Given the direct correlation between the periodontal conditions and duration of CKD, regular biannual dental visits are essential for CKD patients. All physicians are encouraged to include regular oral health checkups in the treatment protocol for CKD patients.

scholarly journals Features of substitution of defects of tooth rows in persons with periodontal tissue diseases of different severity

2021 ◽  
Vol 105 (1) ◽  
pp. 82-87
Author(s):  
O. Doroshenko ◽  
◽  
O. Bida ◽  
Keyword(s):  
Periodontal Disease ◽  
Bone Tissue ◽  
Dental Implants ◽  
Alveolar Bone ◽  
Periodontal Diseases ◽  
Pathological Process ◽  
Periodontal Tissue ◽  
Dental Implantation ◽  
Orthopedic Rehabilitation ◽  
Abutment Teeth

Resume. The high prevalence of periodontal disease causes the urgency of finding ways to improve methods of diagnosis, treatment and prevention of complications of this disease. The complex clinical picture requires a differentiated approach to the choice of orthopedic rehabilitation of such patients taking into account the patient's age, degree of pathological changes and activity of the pathological process with mandatory immobilization of movable teeth by different types of splints and splint dentures. Depending on the degree of pathological changes in periodontal tissues, the size and topography of dentition defects and the severity of destructive-resorptive processes in the alveolar bone, the replacement of dentition defects should be planned using dental implants and splinttype dentures. The aim of the study. Improving the effectiveness of orthopedic treatment of periodontal diseases, burdened by defects of the dentition through the differentiated use of dental implants and splinting structures. Materials and methods. A comprehensive clinical and laboratory examination of 237 patients with clinically diagnosed periodontitis I–III degree, burdened by partial loss of teeth. From the specified contingent of persons we carried out orthopedic treatment of 98 patients aged from 30 to 69 years with periodontal diseases of various severity, aggravated by defects of dentitions of various size and localization. Cone-beam computed tomography was used for objective quantitative and qualitative assessment of periodontal tissue and bone tissue of the edentulous jaw in individuals with various clinical forms of periodontal disease, to determine the relative densitometric density of bone tissue, when planning dental implantation and for control its results. The localization of supracontacts was determined by occlusion. Diagnosis and elimination of traumatic occlusion were performed according to Jenkelson and Schuller [3]. Evaluation of the stability of dental implants was performed by frequency – resonance analysis of the stability of dental implants using the Osstell ISQ device. Results. According to the results of examination of 237 people and the division of patients into three age groups, the clinical features of the pathological process in the age aspect were established. The results of computed tomography of the dental apparatus of the subjects showed that periodontal disease in the age aspect in the dynamics is accompanied by the severity of destructive-resorptive processes in the alveolar bone, which are manifested in a decrease in the relative densitometric density of bone marrow and bone loss. Orthopedic rehabilitation of this contingent of persons was performed with the use of biologically indifferent structural materials and splinting orthopedic structures, including splinting of abutment teeth, removable prosthetics and dental implantation, as well as accompanying physiotherapy of prostheses. In the case of periodontitis of I–II degree with sufficient volume and density of bone tissue in the area of the dentition defect, high clinical efficacy was shown by the use of dental implantation in the case of gradual loading of the dental implant using a superstructure of own development. In the presence of medium and large defects of the dentition on the background of periodontitis II–III severity in the presence of significant pathological mobility of abutment teeth and insufficient volume and density of bone tissue in the area of the defect sufficient clinical effectiveness showed the use of removable dentures own design. Conclusions. Periodontal diseases in the age aspect in the dynamics are accompanied by pronounced destructive-resorptive processes in the alveolar bone, which are manifested by a decrease in the relative densitometric density of bone tissue and progressive loss of height of the alveolar process. Timely application of dental implantation due to the dosed gradual occlusal load on the alveolar bone helps to preserve the structure of the alveolar bone and the height of the alveolar process. In the presence of medium and large defects of the dentition on the background of periodontitis II–III severity in the presence of significant pathological mobility of abutment teeth and insufficient volume and density of bone tissue in the area of the dentition defect, the use of removable dentures of splinttype design is shown. To prevent complications of prosthetics and prolong the use of orthopedic structures, it is advisable to use photodynamic maintenance therapy. Key words: periodontal tissue disease, dentition defect, dental implantation, splint-type denture.

scholarly journals Association between Periodontal Disease and Comorbidities in Saudi’s Eastern Province

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Marwa Madi ◽  
Hatem M. Abuohashish ◽  
Dina Attia ◽  
Norah AlQahtani ◽  
Nabras Alrayes ◽  
...  
Keyword(s):  
Bone Loss ◽  
Periodontal Disease ◽  
Alveolar Bone ◽  
Periodontal Diseases ◽  
Demographic Data ◽  
Alveolar Bone Loss ◽  
Haemoglobin A1c ◽  
Eastern Province ◽  
Pocket Depth ◽  
Multivariable Regression Models

The incidence of periodontal diseases is associated with multiple comorbidities that influence a patient’s treatment planning. This study evaluates the relation between periodontal disease and multiple comorbidities reported in the Saudi population from the Eastern province. This study was conducted on 190 patients, who visited the periodontology clinics at Imam Abdulrahman Bin Faisal University, Saudi Arabia. Demographic data, smoking habits, past medical and dental histories, blood pressure, random blood glucose, and recent haemoglobin A1c were recorded. A comprehensive periodontal examination included the number of missing teeth, pocket depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), and mobility of all teeth except third molars. Radiographic bone loss was measured on standardized full-mouth periapical radiographs. Multivariable regression models were calculated aiming to see the association between different comorbidities and alveolar bone loss with confounders controlled. Out of 190 periodontitis patients, 56 (29.5%) were males and 134 (70.5%) were females. More than half of the patients (60%) were between 26 and 50 years, 30% of them had diabetes, and 18% were smokers. The risk of alveolar bone loss was higher in persons who had diabetes and those who had both diabetes and coronary heart disease than those who did not, although the association was not statistically significant ( B = 1.26 , 95 % CI = − 0.30 , 2.82, and B = 2.86 , 95 % CI = − 1.25 , 6.96, respectively). The risk of alveolar bone loss was significantly higher among persons with diabetes and hypertension ( B = 2.82 and 95 % CI = 0.89 , 4.75). Collectively, the risk of alveolar bone loss in periodontitis patients increases with diabetes in the presence of other comorbidities regardless of smoking or gender.

scholarly journals Localised Aggressive Periodontitis – A Review

2021 ◽  
pp. 166-172
Author(s):  
Milind Wasnik ◽  
Suryakant Kumar ◽  
Arun Sajjanar ◽  
Niharika Gahlod ◽  
Sneha Khekade ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Alveolar Bone ◽  
Periodontal Diseases ◽  
Systemic Disease ◽  
Aggressive Periodontitis ◽  
Permanent Teeth ◽  
Periodontal Health ◽  
Attachment Loss ◽  
Localized Aggressive Periodontitis ◽  
Google Search

The term “periodontal diseases” includes any inherited or acquired disorders of the tissues that are supporting the teeth i. e Gingiva, Cementum, PDL, and Alveolar bone. The periodontal disease can be either localized or generalized. Localized aggressive periodontitis (LAgP) patients have interproximal attachment loss on at least two permanent first molars and incisors, with attachment loss on no more than two teeth other than first molars and incisors. In children and adolescents LAgP occurs without clinical evidence of systemic disease and it is characterized by the severe loss of alveolar bone around permanent teeth [10]. Most commonly the disease is localized to the permanent first molars and incisors. Aim: The aim of this review article is explain in details about aggressive periodontitis including different management aspect of the same. Methods: This paper presents a review of the aggressive periodontitis in children. An electronic search was conducted using Pub Med®/MEDLINE, and Google search using the terms: Periodontium, Localized Aggressive Periodontitis, Children and periodontal health, periodontal health in adolescents, gingival disease in children, periodontal disease in children,  gingivitis, periodontitis, gingival disease and its prevalence, periodontal disease and its prevalence.

A STUDY ON ASSOCIATION 0F TOOTH LOSS & PERIODONTAL DISEASE IN PATIENTS SUFFERING FROM DIABETES FROM BIHAR REGION

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Kumar Manish ◽  
Nikita Raman ◽  
Abhishek Gautam ◽  
Samir Jain ◽  
Prakash Chandra Jha ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Tooth Loss ◽  
Alveolar Bone ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Control Group ◽  
Diabetic Patients ◽  
Diabetes Group ◽  
The Individual ◽  
Tissue Attachment

Diabetes is one of the common diseases of modern times and one of the most common systemic disorder that is connected to periodontal disease. Periodontal diseases are bacterially induced chronic inflammatory diseases affecting the tissues surrounding and supporting the teeth. The lesion begins as gingivitis, an inflammation of the gingival tissues only, and may progress to periodontitis, where destruction of connective tissue attachment and alveolar bone can eventually lead to tooth loss. Hence based on above reported findings the present study was planned for study of prevalence of tooth Loss in Patients Suffering from Diabetes from Bihar Region. The present study was planned in Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar. Total 100 cases were enrolled in the present study. In the enrolled patients 50 cases were Diabetic and 50 were non-diabetic cases. The data generated from the present study concludes that periodontal disease increases in diabetes group than in control group. Thus, a diabetic patient should always see that he/she maintains his/her oral hygiene by following proper tooth brushing habits. Diabetics should take care to see that they get their teeth restored as early as possible, if decayed. They should follow the instructions given by the physician or the dietician for the intake of non-cariogenic diet. The prevention of periodontal breakdown in diabetic patients is mostly based on the education of the individual. Thus, patients should be informed about the importance of oral health for diabetics, and they should be taught that the main symptom of periodontal disease is gingival bleeding. Keywords: Tooth Loss, Diabetes, periodontal disease, bihar, etc

scholarly journals Oral Health Status and Gender-wise Prevalence of Periodontal disease among Cancer Survivors in Pakistan

2020 ◽  
Vol 5 (7) ◽  
pp. 324-326
Author(s):  
Hafiza Armish Siraj ◽  
Umair Hussain ◽  
Shanza Rehman ◽  
Bushra Tariq ◽  
Amina Tariq
Keyword(s):  
Health Status ◽  
Oral Health ◽  
Periodontal Disease ◽  
Cancer Survivors ◽  
Oral Health Status ◽  
And Gender

scholarly journals Current Status of Proteomic Technologies for Discovering and Identifying Gingival Crevicular Fluid Biomarkers for Periodontal Disease

2018 ◽  
Vol 20 (1) ◽  
pp. 86 ◽  
Author(s):  
Sachio Tsuchida ◽  
Mamoru Satoh ◽  
Masaki Takiwaki ◽  
Fumio Nomura
Keyword(s):  
Periodontal Disease ◽  
Alveolar Bone ◽  
Gingival Crevicular Fluid ◽  
Periodontal Diseases ◽  
Protein Composition ◽  
Current Status ◽  
Promising Tool ◽  
Proteomic Approach ◽  
Advanced Stages ◽  
Crevicular Fluid

Periodontal disease is caused by bacteria in dental biofilms. To eliminate the bacteria, immune system cells release substances that inflame and damage the gums, periodontal ligament, or alveolar bone, leading to swollen bleeding gums, which is a sign of gingivitis. Damage from periodontal disease can cause teeth to loosen also. Studies have demonstrated the proteomic approach to be a promising tool for the discovery and identification of biochemical markers of periodontal diseases. Recently, many studies have applied expression proteomics to identify proteins whose expression levels are altered by disease. As a fluid lying in close proximity to the periodontal tissue, the gingival crevicular fluid (GCF) is the principal target in the search for periodontal disease biomarkers because its protein composition may reflect the disease pathophysiology. Biochemical marker analysis of GCF is effective for objective diagnosis in the early and advanced stages of periodontal disease. Periodontal diseases are also promising targets for proteomics, and several groups, including ours, have applied proteomics in the search for GCF biomarkers of periodontal diseases. This search is of continuing interest in the field of experimental and clinical periodontal disease research. In this article, we summarize the current situation of proteomic technologies to discover and identify GCF biomarkers for periodontal diseases.

scholarly journals Animal Models for Periodontal Disease

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Helieh S. Oz ◽  
David A. Puleo
Keyword(s):  
Animal Models ◽  
Periodontal Disease ◽  
Alveolar Bone ◽  
Cultured Cells ◽  
Periodontal Diseases ◽  
Oral Bacteria ◽  
Host Responses ◽  
Advantages And Disadvantages ◽  
Wide Range

Animal models and cell cultures have contributed new knowledge in biological sciences, including periodontology. Although cultured cells can be used to study physiological processes that occur during the pathogenesis of periodontitis, the complex host response fundamentally responsible for this disease cannot be reproducedin vitro. Among the animal kingdom, rodents, rabbits, pigs, dogs, and nonhuman primates have been used to model human periodontitis, each with advantages and disadvantages. Periodontitis commonly has been induced by placing a bacterial plaque retentive ligature in the gingival sulcus around the molar teeth. In addition, alveolar bone loss has been induced by inoculation or injection of human oral bacteria (e.g.,Porphyromonas gingivalis) in different animal models. While animal models have provided a wide range of important data, it is sometimes difficult to determine whether the findings are applicable to humans. In addition, variability in host responses to bacterial infection among individuals contributes significantly to the expression of periodontal diseases. A practical and highly reproducible model that truly mimics the natural pathogenesis of human periodontal disease has yet to be developed.

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